Substance-Related Disorders
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 70 Companies   97 Products   97 Products   124 Mechanisms of Action   1 Trial   1962 News 


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  • ||||||||||  Enrollment open:  OTS ETOH-3: Oxytocin Treatment of Alcohol Dependence (clinicaltrials.gov) -  May 27, 2016   
    P2,  N=50, Recruiting, 
    Trial primary completion date: Oct 2015 --> Oct 2016 Not yet recruiting --> Recruiting
  • ||||||||||  Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
    Trial completion:  Study of Long-Acting Injectable Naltrexone to Treat Cannabis Dependence (clinicaltrials.gov) -  May 18, 2016   
    P1/2,  N=12, Completed, 
    Recruiting --> Active, not recruiting Recruiting --> Completed
  • ||||||||||  Trial primary completion date:  Adaptive Treatment for Adolescent Cannabis Use Disorders (clinicaltrials.gov) -  May 13, 2016   
    P=N/A,  N=172, Active, not recruiting, 
    Recruiting --> Completed Trial primary completion date: Feb 2016 --> Jul 2016
  • ||||||||||  Enrollment closed, Enrollment change:  Delivery of Anxiety Disorder Treatment in Addictions Centers (clinicaltrials.gov) -  May 13, 2016   
    P=N/A,  N=98, Active, not recruiting, 
    Terminated --> Withdrawn Recruiting --> Active, not recruiting | N=80 --> 98
  • ||||||||||  Enrollment closed, Enrollment change, Trial primary completion date:  Tailored Mobile Text Messaging to Reduce Problem Drinking (clinicaltrials.gov) -  May 12, 2016   
    P=N/A,  N=174, Active, not recruiting, 
    Active, not recruiting --> Completed Recruiting --> Active, not recruiting | N=300 --> 174 | Trial primary completion date: Jul 2015 --> Dec 2015
  • ||||||||||  Trial primary completion date:  Project Relay Model for Recruiting Alcohol Dependent Patients in General Hospitals (clinicaltrials.gov) -  May 11, 2016   
    P=N/A,  N=1000, Recruiting, 
    Recruiting --> Active, not recruiting | N=300 --> 174 | Trial primary completion date: Jul 2015 --> Dec 2015 Trial primary completion date: Feb 2016 --> Jun 2017
  • ||||||||||  Campral EC (acamprosate delayed release) / EMD Serono, Nippon Shinyaku
    Trial termination:  Study of Acamprosate to Prevent Alcohol Relapse in Criminal Justice Supervisees (clinicaltrials.gov) -  May 11, 2016   
    P4,  N=26, Terminated, 
    Trial primary completion date: Feb 2016 --> Jun 2017 Completed --> Terminated; Not enough sugjects enrolled before funding ran out
  • ||||||||||  Trial completion, Trial primary completion date:  Phendimetrazine and Cocaine (clinicaltrials.gov) -  May 11, 2016   
    P0,  N=10, Completed, 
    Completed --> Terminated; Not enough sugjects enrolled before funding ran out Recruiting --> Completed | Trial primary completion date: May 2016 --> Dec 2015
  • ||||||||||  Trial primary completion date:  Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress (clinicaltrials.gov) -  May 4, 2016   
    P1,  N=66, Recruiting, 
    Recruiting --> Completed | Trial primary completion date: May 2016 --> Dec 2015 Trial primary completion date: Jan 2016 --> Jan 2017
  • ||||||||||  Trial primary completion date, HEOR:  Medical Marijuana Use in HIV+ Patients Prospective Cohort Study (clinicaltrials.gov) -  Apr 27, 2016   
    P=N/A,  N=150, Active, not recruiting, 
    Active, not recruiting --> Completed Trial primary completion date: May 2016 --> Sep 2016
  • ||||||||||  Enrollment closed, Trial primary completion date:  Integrated Collaborative Care for Substance Use Disorders (clinicaltrials.gov) -  Apr 19, 2016   
    P=N/A,  N=397, Active, not recruiting, 
    Active, not recruiting --> Completed | N=1000 --> 1754 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Jul 2016
  • ||||||||||  Arcalyst (rilonacept) / Regeneron, Kiniksa
    Trial completion, Enrollment change, Trial primary completion date:  A Safety and Efficacy Study of Mycophenolate Mofetil and Rilonacept in Patients With Alcoholic Hepatitis (clinicaltrials.gov) -  Apr 19, 2016   
    P2,  N=5, Completed, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2017 --> Jul 2016 Not yet recruiting --> Completed | N=186 --> 5 | Trial primary completion date: Sep 2018 --> Apr 2016
  • ||||||||||  isradipine / Generic mfg.
    Trial completion, Enrollment change:  Improving Buprenorphine Detoxification Outcomes With Isradipine (clinicaltrials.gov) -  Apr 19, 2016   
    P1/2,  N=28, Completed, 
    Not yet recruiting --> Completed | N=186 --> 5 | Trial primary completion date: Sep 2018 --> Apr 2016 Recruiting --> Completed | N=60 --> 28
  • ||||||||||  Trial completion, Compliance:  MAPIT: Motivational Assessment Program to Initiate Treatment (clinicaltrials.gov) -  Apr 14, 2016   
    P=N/A,  N=380, Completed, 
    Recruiting --> Active, not recruiting Active, not recruiting --> Completed
  • ||||||||||  Enrollment closed, Enrollment change, Trial primary completion date:  SBIRT Implementation for Adolescents in Urban Federally Qualified Health Centers (clinicaltrials.gov) -  Apr 8, 2016   
    P=N/A,  N=98, Active, not recruiting, 
    Active, not recruiting --> Completed | Phase classification: PN/A --> P2/3 Recruiting --> Active, not recruiting | N=2168 --> 98 | Trial primary completion date: Mar 2016 --> Jun 2016
  • ||||||||||  amphetamine/dextroamphetamine immediate release tablet / Generic mfg., topiramate / Generic mfg.
    Trial primary completion date:  TACT2: Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence (clinicaltrials.gov) -  Apr 7, 2016   
    P2/3,  N=176, Recruiting, 
    Recruiting --> Active, not recruiting | N=2168 --> 98 | Trial primary completion date: Mar 2016 --> Jun 2016 Trial primary completion date: Jun 2016 --> Feb 2017
  • ||||||||||  quetiapine / Generic mfg.
    Enrollment change:  Quetiapine for Bipolar Disorder and Alcohol Dependence (clinicaltrials.gov) -  Apr 7, 2016   
    P4,  N=90, Completed, 
    Trial primary completion date: Jun 2016 --> Feb 2017 N=120 --> 90
  • ||||||||||  morphine sulphate / Generic mfg.
    Trial primary completion date:  Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS) (clinicaltrials.gov) -  Mar 31, 2016   
    P2,  N=64, Enrolling by invitation, 
    Recruiting --> Active, not recruiting | N=100 --> 312 | Trial primary completion date: May 2016 --> Oct 2015 Trial primary completion date: Dec 2015 --> Jun 2017
  • ||||||||||  Chantix (varenicline) / Pfizer
    Trial completion, Trial primary completion date:  Treatment of Smoking Among Individuals With PTSD (clinicaltrials.gov) -  Mar 31, 2016   
    P2,  N=142, Completed, 
    Trial primary completion date: Dec 2015 --> Jun 2017 Active, not recruiting --> Completed | Trial primary completion date: Dec 2014 --> Dec 2015
  • ||||||||||  NN1213 / Novo Nordisk
    Trial completion:  Maintaining Abstinence in Chronic Cigarette Smokers - 1 (clinicaltrials.gov) -  Mar 30, 2016   
    P2,  N=407, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Dec 2014 --> Dec 2015 Active, not recruiting --> Completed
  • ||||||||||  Selincro (nalmefene oral) / Lundbeck, Acorda
    Trial termination:  Study of 18 mg Selincro (clinicaltrials.gov) -  Mar 30, 2016   
    P4,  N=378, Terminated, 
    Active, not recruiting --> Completed Completed --> Terminated; The study was terminated due to enrolment challenges
  • ||||||||||  Trial primary completion date:  OPAL: "Opiates and PhArmacoLogy" (clinicaltrials.gov) -  Mar 25, 2016   
    P=N/A,  N=354, Recruiting, 
    Trial primary completion date: Nov 2015 --> Nov 2016 Trial primary completion date: Aug 2015 --> Jun 2016
  • ||||||||||  baclofen / Generic mfg.
    Enrollment change, Trial termination, Trial primary completion date:  Preventing Alcohol Withdrawal With Oral Baclofen (clinicaltrials.gov) -  Mar 24, 2016   
    P2,  N=17, Terminated, 
    Trial primary completion date: Aug 2015 --> Jun 2016 N=212 --> 17 | Recruiting --> Terminated | Trial primary completion date: Apr 2016 --> Jun 2015; The enrollment in the study was too limited for meaningful data analysis.
  • ||||||||||  Enrollment open:  Automated Recovery Line for Medication Assisted Treatment (clinicaltrials.gov) -  Mar 22, 2016   
    P1/2,  N=60, Recruiting, 
    N=212 --> 17 | Recruiting --> Terminated | Trial primary completion date: Apr 2016 --> Jun 2015; The enrollment in the study was too limited for meaningful data analysis. Not yet recruiting --> Recruiting
  • ||||||||||  aripiprazole / Generic mfg.
    Trial completion:  Aripiprazole Effects on Alcohol Drinking and Craving (clinicaltrials.gov) -  Mar 18, 2016   
    P3,  N=99, Completed, 
    Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Mar 2016 Recruiting --> Completed