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70 Companies |
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97 Products |
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97 Products |
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124 Mechanisms of Action |
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1 Trial |
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1962 News |
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- Enrollment change: The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD (clinicaltrials.gov) - Dec 12, 2012
P2, N=58, Completed, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
N=120 --> 58
- | memantine / Generic mfg.
Enrollment change: NAMHS: Memantine as a Supplement to Naltrexone in Treating Heroin Dependence (clinicaltrials.gov) - Dec 12, 2012
P2/3, N=82, Completed, Sponsor: New York State Psychiatric Institute
N=120 --> 58 N=200 --> 82
- Enrollment closed: Adolescent Involvement in Parental Substance Abuse Treatment (clinicaltrials.gov) - Dec 12, 2012
P1/2, N=183, Active, not recruiting, Sponsor: Ohio State University
N=200 --> 82 Recruiting --> Active, not recruiting
- | Enrollment closed: Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults (clinicaltrials.gov) - Dec 12, 2012
P3, N=75, Active, not recruiting, Sponsor: New York State Psychiatric Institute
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- mirtazapine / Generic mfg.
Enrollment change: Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression (clinicaltrials.gov) - Dec 10, 2012
P2, N=107, Completed, Sponsor: New York State Psychiatric Institute
Recruiting --> Active, not recruiting N=260 --> 107
- Sativex (nabiximols) / Jazz
New P2 trial: Sativex and Behavioral-relapse Prevention Strategy in Cannabis Dependence (clinicaltrials.gov) - Dec 10, 2012
P2, N=45, Recruiting, Sponsor: Centre for Addiction and Mental Health
- mirtazapine / Generic mfg.
Trial completion: Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression (clinicaltrials.gov) - Dec 10, 2012
P2, N=107, Completed, Sponsor: New York State Psychiatric Institute
N=260 --> 107 Recruiting --> Completed
- Trial completion: RIHTA: Adipose Tissue Involvement in Alcohol-induced Liver Inflammation in Human (clinicaltrials.gov) - Dec 9, 2012
P=N/A, N=47, Completed, Sponsor: Assistance Publique - H
Recruiting --> Completed Recruiting --> Completed
- baclofen / Generic mfg.
New P1 trial: Oral and IV Baclofen in Adult Volunteers (clinicaltrials.gov) - Dec 3, 2012
P1, N=12, Not yet recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
- Trial completion: Prevention of Weight Gain in Early Psychoses (clinicaltrials.gov) - Dec 3, 2012
P=N/A, N=70, Completed, Sponsor: Centre for Addiction and Mental Health
Recruiting --> Completed Recruiting --> Completed
- Trial completion: GET UP: Partner-Specific HIV Risk Reduction Intervention for Drug-Using Adolescents (clinicaltrials.gov) - Dec 2, 2012
P=N/A, N=59, Completed, Sponsor: Women and Infants Hospital of Rhode Island
Recruiting --> Completed Active, not recruiting --> Completed
- modafinil / Generic mfg.
Enrollment change: A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence (clinicaltrials.gov) - Nov 29, 2012
P2, N=15, Completed, Sponsor: Research Foundation for Mental Hygiene, Inc.
Active, not recruiting --> Completed N=30 --> 15
- modafinil / Generic mfg.
Trial completion: A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence (clinicaltrials.gov) - Nov 29, 2012
P2, N=15, Completed, Sponsor: Research Foundation for Mental Hygiene, Inc.
N=30 --> 15 Recruiting --> Completed
- |||||||||| baclofen / Generic mfg.
New P3 trial: ALPADIR: Efficacy and Safety of Baclofen for Maintenance of Abstinence in Alcohol Dependent Patients (clinicaltrials.gov) - Nov 28, 2012
P3, N=316, Active, not recruiting, Sponsor: Ethypharm
- ||||| Sublocade (buprenorphine once-monthly depot) / Indivior
New P2 trial: Multiple Dose Pharmacokinetics Depot Buprenorphine in Opioid-Dependent Subjects (clinicaltrials.gov) - Nov 28, 2012
P2, N=90, Recruiting, Sponsor: Reckitt Benckiser Pharmaceuticals Inc.
- | GSK1521498 / GSK
New P1 trial: To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK1521498 and Naltrexone on Physiological and Behavioural Markers of Brain Function in Healthy Social Drinkers (clinicaltrials.gov) - Nov 28, 2012
P1, N=48, Recruiting, Sponsor: GlaxoSmithKline
- Trial completion: Assessment of Cannabis Craving in Schizophrenia Using Virtual Reality (clinicaltrials.gov) - Nov 26, 2012
P=N/A, N=25, Completed, Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting --> Completed Recruiting --> Completed
- disulfiram / Generic mfg.
Biomarker, Trial completion: Pharmacogenetics of Disulfiram for Cocaine (clinicaltrials.gov) - Nov 26, 2012
P2, N=93, Completed, Sponsor: Baylor College of Medicine
Recruiting --> Completed Active, not recruiting --> Completed
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Trial termination: Pilot Study of Depot NTX in Homeless Veterans (clinicaltrials.gov) - Nov 25, 2012
P4, N=7, Terminated, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Active, not recruiting --> Terminated; Poor enrollment
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Enrollment change: Pilot Study of Depot NTX in Homeless Veterans (clinicaltrials.gov) - Nov 25, 2012
P4, N=7, Terminated, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Terminated; Poor enrollment N=20 --> 7
- morphine sulphate / Generic mfg., clonidine / Generic mfg.
New P4 trial: NAS Treatment - Opiate Versus Non-Opiate (clinicaltrials.gov) - Nov 25, 2012
P4, N=34, Active, not recruiting, Sponsor: University of Kentucky
- Enrollment open: Evaluation of Impulsivity on Cocaine and Crack Addicts (clinicaltrials.gov) - Nov 22, 2012
P=N/A, N=60, Recruiting, Sponsor: Federal University of S
N=20 --> 7 Not yet recruiting --> Recruiting
- methamphetamine / Generic mfg.
Trial withdrawal: A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People Who Abuse Methamphetamine (clinicaltrials.gov) - Nov 19, 2012
P=N/A, N=0, Withdrawn, Sponsor: National Institute of Dental and Craniofacial Research (NIDCR)
Not yet recruiting --> Recruiting Recruiting --> Withdrawn
- nepicastat (APL-1401) / Asieris
Trial initiation date: A Multi-Center Trial of Nepicastat for Cocaine Dependence (clinicaltrials.gov) - Nov 19, 2012
P2, N=180, Recruiting, Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting --> Withdrawn Initiation date: Jan 2013 --> Apr 2013
- methamphetamine / Generic mfg.
Enrollment change: A Comparative Feasibility Study to Assess the Prevalence and Severity of Dental Caries in Incarcerated People Who Abuse Methamphetamine (clinicaltrials.gov) - Nov 19, 2012
P=N/A, N=0, Withdrawn, Sponsor: National Institute of Dental and Craniofacial Research (NIDCR)
Initiation date: Jan 2013 --> Apr 2013 N=180 --> 0
- amphetamine / Generic mfg.
Enrollment change: Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) (clinicaltrials.gov) - Nov 19, 2012
P=N/A, N=22, Completed, Sponsor: Wayne State University
N=180 --> 0 N=40 --> 22
- amphetamine / Generic mfg.
Trial completion: Treatment Study: Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine (ARC) (clinicaltrials.gov) - Nov 19, 2012
P=N/A, N=22, Completed, Sponsor: Wayne State University
N=40 --> 22 Recruiting --> Completed
- Trial suspension: CIRROX: Phlebotomy and Risk of Hepatocellular Carcinoma in Patients With Compensated Alcoholic Cirrhosis (clinicaltrials.gov) - Nov 18, 2012
P3, N=324, Suspended, Sponsor: Assistance Publique - H
Recruiting --> Completed Not yet recruiting --> Suspended
- naltrexone / Generic mfg.
Enrollment change: Will Having Alcohol Treatment Improve Functioning? (clinicaltrials.gov) - Nov 15, 2012
P2, N=19, Completed, Sponsor: University of Florida
Not yet recruiting --> Suspended N=90 --> 19
- naltrexone / Generic mfg.
Trial completion: Will Having Alcohol Treatment Improve Functioning? (clinicaltrials.gov) - Nov 15, 2012
P2, N=19, Completed, Sponsor: University of Florida
N=90 --> 19 Recruiting --> Completed
- dronabinol oral / Generic mfg.
Enrollment change: Dronabinol Interactions With Cognitive Enhancing Drug in Humans (clinicaltrials.gov) - Nov 14, 2012
P=N/A, N=53, Completed, Sponsor: Yale University
Recruiting --> Completed N=15 --> 53
- |||| Enrollment open: Helping Hospitalized Patients Quit Smoking (clinicaltrials.gov) - Nov 8, 2012
P4, N=600, Recruiting, Sponsor: Mayo Clinic
N=15 --> 53 Not yet recruiting --> Recruiting
- tolcapone / Generic mfg.
Trial completion: Neural Substrates in Nicotine Withdrawal (clinicaltrials.gov) - Nov 8, 2012
P2, N=28, Completed, Sponsor: University of Pennsylvania
Not yet recruiting --> Recruiting Recruiting --> Completed
- phenobarbital / Generic mfg., methadone / Generic mfg.
New P4 trial, Combination therapy: HOMENOW: Treatment of Neonatal Abstinence Syndrome (clinicaltrials.gov) - Nov 6, 2012
P4, N=40, Completed, Sponsor: Eastern Maine Medical Center
- methadone / Generic mfg.
New P1 trial: Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin (clinicaltrials.gov) - Nov 6, 2012
P1, N=40, Not yet recruiting, Sponsor: Johns Hopkins University
- Enrollment closed: Brief Intervention in Primary Care for Problem Drug Use and Abuse (clinicaltrials.gov) - Nov 5, 2012
P=N/A, N=1000, Active, not recruiting, Sponsor: University of Washington
Recruiting --> Completed Recruiting --> Active, not recruiting
- atomoxetine / Generic mfg.
Trial completion: Effectiveness of ATMX in Treating Adolescents With ADHD and SUD (clinicaltrials.gov) - Nov 5, 2012
P4, N=108, Completed, Sponsor: Massachusetts General Hospital
Recruiting --> Active, not recruiting Recruiting --> Completed
- atomoxetine / Generic mfg.
Trial withdrawal: Efficacy of Atomoxetine for ADHD in Adolescents and Young Adults With SUD (clinicaltrials.gov) - Nov 4, 2012
P4, N=0, Withdrawn, Sponsor: Massachusetts General Hospital
Recruiting --> Completed Terminated --> Withdrawn
- Enrollment change: GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence (clinicaltrials.gov) - Nov 1, 2012
P=N/A, N=2, Completed, Sponsor: Yale University
Terminated --> Withdrawn N=60 --> 2
- naltrexone / Generic mfg.
Enrollment change, Grant: Effectiveness of Naltrexone Versus Placebo to Reduce Craving for Alcohol With Evaluation of Genetic Variability. (clinicaltrials.gov) - Nov 1, 2012
P4, N=83, Completed, Sponsor: Medical University of South Carolina
N=60 --> 2 N=300 --> 83
- Trial completion: Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking (clinicaltrials.gov) - Nov 1, 2012
P=N/A, N=89, Completed, Sponsor: Research Foundation for Mental Hygiene, Inc.
N=300 --> 83 Active, not recruiting --> Completed
- Trial completion: GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence (clinicaltrials.gov) - Nov 1, 2012
P=N/A, N=2, Completed, Sponsor: Yale University
Active, not recruiting --> Completed Recruiting --> Completed
- | naltrexone / Generic mfg.
Trial completion: Medication and Counseling for Controlled Drinking (Project SMART) (clinicaltrials.gov) - Nov 1, 2012
P3, N=200, Completed, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruiting --> Completed Recruiting --> Completed
- Trial initiation date: Nicotine Replacement Therapy in the Intensive Care Unit (clinicaltrials.gov) - Oct 31, 2012
P4, N=100, Recruiting, Sponsor: Gelderse Vallei Hospital
Recruiting --> Completed Initiation date: Sep 2011 --> Jun 2012
- Enrollment open: Nicotine Replacement Therapy in the Intensive Care Unit (clinicaltrials.gov) - Oct 31, 2012
P4, N=100, Recruiting, Sponsor: Gelderse Vallei Hospital
Initiation date: Sep 2011 --> Jun 2012 Not yet recruiting --> Recruiting
- Enrollment change: BIRCWH: Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes (clinicaltrials.gov) - Oct 30, 2012
P=N/A, N=31, Completed, Sponsor: Medical University of South Carolina
Not yet recruiting --> Recruiting N=20 --> 31
- New P2 trial: Acute Effects of Cortisol on Heroin Craving in Opioid Dependence (Ghost-Basel) (clinicaltrials.gov) - Oct 30, 2012
P2, N=30, Completed, Sponsor: Prof. Dominique de Quervain, MD
- Trial completion: Attempts to Stop/Reduce Marijuana Among Dependent Users (clinicaltrials.gov) - Oct 30, 2012
P=N/A, N=234, Completed, Sponsor: University of Vermont
N=20 --> 31 Active, not recruiting --> Completed
- Trial completion: BIRCWH: Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes (clinicaltrials.gov) - Oct 30, 2012
P=N/A, N=31, Completed, Sponsor: Medical University of South Carolina
Active, not recruiting --> Completed Recruiting --> Completed
- Chantix (varenicline) / Pfizer
Trial completion, MRI: Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on Smokers (clinicaltrials.gov) - Oct 30, 2012
P=N/A, N=21, Completed, Sponsor: Medical University of South Carolina
Recruiting --> Completed Active, not recruiting --> Completed