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70 Companies |
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97 Products |
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97 Products |
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124 Mechanisms of Action |
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1 Trial |
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1962 News |
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- |||| Campral EC (acamprosate delayed release) / EMD Serono, Nippon Shinyaku
Trial completion: Acamprosate: Genes Associated With Response (clinicaltrials.gov) - Mar 19, 2013
P4, N=485, Completed, Sponsor: Mayo Clinic
Recruiting --> Completed
- | Trial completion: Adolescent Drug and HIV Prevention in South Africa (clinicaltrials.gov) - Mar 18, 2013
P2/3, N=7695, Completed, Sponsor: Penn State University
Recruiting --> Completed Active, not recruiting --> Completed
- || amphetamine/dextroamphetamine immediate release tablet / Generic mfg., topiramate / Generic mfg.
New P2/3 trial: TACT2: Multicenter Trial of Combined Pharmacotherapy to Treat Cocaine Dependence (clinicaltrials.gov) - Mar 13, 2013
P2/3, N=176, Recruiting, Sponsor: New York State Psychiatric Institute
- Zyflo (zileuton) / Chiesi
Trial completion: Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers (clinicaltrials.gov) - Mar 13, 2013
P1/2, N=80, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | ondansetron / Generic mfg., naltrexone / Generic mfg.
Trial completion: Combined Pharmacotherapies for Alcoholism (clinicaltrials.gov) - Mar 13, 2013
P3, N=300, Completed, Sponsor: Bankole Johnson
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial withdrawal: Treatment of Alcohol-Related Hepatitis With Arginine (clinicaltrials.gov) - Mar 10, 2013
P2, N=0, Withdrawn, Sponsor: National Center for Complementary and Alternative Medicine (NCCAM)
Active, not recruiting --> Completed Terminated --> Withdrawn
- Enrollment change, MRI: Neural Mechanisms Underlying Alcohol Induced Disinhibition (clinicaltrials.gov) - Mar 10, 2013
P=N/A, N=50, Completed, Sponsor: Technische Universit
Terminated --> Withdrawn N=40 --> 50
- Enrollment change: Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethanol (CASE) (clinicaltrials.gov) - Mar 10, 2013
P=N/A, N=96, Active, not recruiting, Sponsor: Technische Universit
N=40 --> 50 N=80 --> 96
- Enrollment closed: Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethanol (CASE) (clinicaltrials.gov) - Mar 10, 2013
P=N/A, N=96, Active, not recruiting, Sponsor: Technische Universit
N=80 --> 96 Enrolling by invitation --> Active, not recruiting
- Trial completion, MRI: Neural Mechanisms Underlying Alcohol Induced Disinhibition (clinicaltrials.gov) - Mar 10, 2013
P=N/A, N=50, Completed, Sponsor: Technische Universit
Enrolling by invitation --> Active, not recruiting Enrolling by invitation --> Completed
- |||| Enrollment open: ABT-436 for Alcohol Dependence (clinicaltrials.gov) - Mar 7, 2013
P2, N=148, Recruiting, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
- GSK1521498 / GSK
Enrollment open: To Evaluate the Influence of the A118G Polymorphism in the mu Opioid Receptor Gene (OPRM1) on Effects of GSK1521498 and Naltrexone on Physiological and Behavioural Markers of Brain Function in Healthy Social Drinkers (clinicaltrials.gov) - Mar 6, 2013
P1, N=48, Recruiting, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Enrollment change: Assessment and Treatment of Caffeine Dependence (clinicaltrials.gov) - Mar 5, 2013
P1, N=94, Completed, Sponsor: Johns Hopkins University
Not yet recruiting --> Recruiting N=220 --> 94
- Sativex (nabiximols) / Jazz
Enrollment open: Sativex and Behavioral-relapse Prevention Strategy in Cannabis Dependence (clinicaltrials.gov) - Mar 4, 2013
P2, N=45, Recruiting, Sponsor: Centre for Addiction and Mental Health
N=220 --> 94 Not yet recruiting --> Recruiting
- dronabinol oral / Generic mfg.
Trial completion: Ph1 Marinol Interaction Study - Part 2 - 1 (clinicaltrials.gov) - Mar 4, 2013
P1, N=12, Completed, Sponsor: National Institute on Drug Abuse (NIDA)
Not yet recruiting --> Recruiting Recruiting --> Completed
- morphine sulphate / Generic mfg., methadone / Generic mfg.
New P4 trial: Comparison Between Methadone and Morphine for Neonatal Opiate Withdrawal (clinicaltrials.gov) - Mar 3, 2013
P4, N=31, Completed, Sponsor: Eastern Maine Medical Center
- Enrollment closed: BRAC: Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence (clinicaltrials.gov) - Mar 3, 2013
P2, N=60, Active, not recruiting, Sponsor: University of Cincinnati
Recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion: Smoking-induced Dopamine Release: a [11C]-(+)-PHNO PET Study in Humans (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=10, Completed, Sponsor: Centre for Addiction and Mental Health
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Sativex (nabiximols) / Jazz
Enrollment open: Fixed or Self-Titrated Dosages of Sativex on Cannabis Users (clinicaltrials.gov) - Feb 27, 2013
P=N/A, N=10, Recruiting, Sponsor: Centre for Addiction and Mental Health
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | ondansetron intravenous / Generic mfg.
New P1/2 trial: Zofran_PK: How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant Women (clinicaltrials.gov) - Feb 26, 2013
P1/2, N=100, Completed, Sponsor: Stanford University
- | memantine / Generic mfg.
Trial completion: MM opioid: Psychopharmacotherapy in Multiple Substances Abuse (clinicaltrials.gov) - Feb 26, 2013
P3, N=200, Completed, Sponsor: National Cheng-Kung University Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- Chantix (varenicline) / Pfizer
Enrollment change: A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=99, Completed, Sponsor: University of California, San Francisco
Recruiting --> Completed N=150 --> 99
- ||||| BTRX-246040 / Neumora Therap
New P2 trial: A Study of LY2940094 in Participants With Alcohol Dependency (clinicaltrials.gov) - Feb 21, 2013
P2, N=130, Active, not recruiting, Sponsor: Eli Lilly and Company
- New P1/2 trial: Pharmacokinetic and Pharmacodynamic Effects of Passive Cannabis Inhalation (clinicaltrials.gov) - Feb 21, 2013
P1/2, N=38, Completed, Sponsor: Ryan Vandrey
- Chantix (varenicline) / Pfizer
Trial completion: A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=99, Completed, Sponsor: University of California, San Francisco
N=150 --> 99 Active, not recruiting --> Completed
- Trial completion: Improving Hepatitis C Treatment in Injection Drug Users (clinicaltrials.gov) - Feb 21, 2013
P4, N=111, Completed, Sponsor: State University of New York - Upstate Medical University
Active, not recruiting --> Completed Active, not recruiting --> Completed
- modafinil / Generic mfg.
Enrollment change: Stress and Medication Effects on Cocaine Cue Reactivity (clinicaltrials.gov) - Feb 20, 2013
P2, N=109, Completed, Sponsor: Medical University of South Carolina
Active, not recruiting --> Completed N=150 --> 109
- modafinil / Generic mfg.
Trial completion: Stress and Medication Effects on Cocaine Cue Reactivity (clinicaltrials.gov) - Feb 20, 2013
P2, N=109, Completed, Sponsor: Medical University of South Carolina
N=150 --> 109 Recruiting --> Completed
- quetiapine / Generic mfg.
Trial termination, Combination therapy: Anxiety in Recovering Opiate Dependence (clinicaltrials.gov) - Feb 14, 2013
P4, N=14, Terminated, Sponsor: Beth Israel Medical Center
Recruiting --> Completed Suspended --> Terminated; The study was not completed, the funding sponsor lost interest.
- quetiapine / Generic mfg.
Enrollment change, Combination therapy: Anxiety in Recovering Opiate Dependence (clinicaltrials.gov) - Feb 14, 2013
P4, N=14, Terminated, Sponsor: Beth Israel Medical Center
Suspended --> Terminated; The study was not completed, the funding sponsor lost interest. N=40 --> 14
- Chantix (varenicline) / Pfizer
Trial completion: Distribution of Bupropion and Varenicline to Increase Smoking Cessation Attempts (clinicaltrials.gov) - Feb 13, 2013
P4, N=923, Completed, Sponsor: Centre for Addiction and Mental Health
N=40 --> 14 Active, not recruiting --> Completed
- ||||| Chantix (varenicline) / Pfizer
Enrollment closed: Inter-ACTIV: Efficacy and Safety of Varenicline Among HIV-infected Patients (clinicaltrials.gov) - Feb 11, 2013
P3, N=248, Active, not recruiting, Sponsor: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- | MK-8435 / Merck (MSD)
Trial termination: Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants With Alcohol Dependence (P05718) (clinicaltrials.gov) - Feb 5, 2013
P2, N=141, Terminated, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Active, not recruiting Completed --> Terminated; Based on the outcome of a planned interim analysis, the study was stopped early due to futility.
- MK-8435 / Merck (MSD)
Enrollment change: Trial Investigating the Efficacy and Safety of SCH 900435 (Org 25935) in Relapse Prevention in Participants With Alcohol Dependence (P05718) (clinicaltrials.gov) - Feb 5, 2013
P2, N=141, Terminated, Sponsor: Merck Sharp & Dohme Corp.
Completed --> Terminated; Based on the outcome of a planned interim analysis, the study was stopped early due to futility. N=300 --> 141
- |||||| Enrollment open: Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure (clinicaltrials.gov) - Feb 5, 2013
P3, N=200, Recruiting, Sponsor: Vital Therapies, Inc.
N=300 --> 141 Not yet recruiting --> Recruiting
- citicoline / Generic mfg.
Trial initiation date: Citicoline and Omega-3 Fatty Acid Effects in Veterans With Traumatic Brain Injury (TBI) (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=100, Not yet recruiting, Sponsor: Deborah Yurgelun-Todd
Not yet recruiting --> Recruiting Initiation date: Jul 2012 --> Nov 2013
- New P1 trial: Trial of Computerized SBI to Reduce Teen Alcohol Use (clinicaltrials.gov) - Feb 4, 2013
P1, N=2500, Not yet recruiting, Sponsor: Children's Hospital Boston
- Trial completion: Antioxidant Replacement Therapy in Patients With Alcohol Abuse (clinicaltrials.gov) - Feb 4, 2013
P2, N=38, Completed, Sponsor: University of Colorado, Denver
Initiation date: Jul 2012 --> Nov 2013 Recruiting --> Completed
- Enrollment change: Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers (clinicaltrials.gov) - Feb 3, 2013
P2, N=26, Completed, Sponsor: New York State Psychiatric Institute
Recruiting --> Completed N=48 --> 26
- Lucemyra (lofexidine) / US WorldMeds, Stada
Enrollment change: Effect of Lofexidine and Oral THC on Marijuana Withdrawal and Relapse (clinicaltrials.gov) - Feb 3, 2013
P2, N=8, Completed, Sponsor: New York State Psychiatric Institute
N=48 --> 26 N=20 --> 8
- baclofen / Generic mfg.
Enrollment change: Effect of Baclofen on Marijuana Withdrawal and Relapse (clinicaltrials.gov) - Feb 3, 2013
P2, N=13, Completed, Sponsor: New York State Psychiatric Institute
N=20 --> 8 N=20 --> 13
- | New P4 trial: Helping Those With Mental Illness Quit Smoking (clinicaltrials.gov) - Feb 3, 2013
P4, N=272, Recruiting, Sponsor: University of Wisconsin, Madison
- Trial completion: Comparison of the Analgesic Effects of Dronabinol and Smoked Marijuana in Daily Marijuana Smokers (clinicaltrials.gov) - Feb 3, 2013
P2, N=26, Completed, Sponsor: New York State Psychiatric Institute
N=20 --> 13 Recruiting --> Completed
- | Trial completion: Prescription Opioid Addiction Treatment Study (POATS) (clinicaltrials.gov) - Jan 31, 2013
P3, N=653, Completed, Sponsor: Mclean Hospital
Recruiting --> Completed Active, not recruiting --> Completed
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Trial initiation date, Adverse events: XRNT: Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT (clinicaltrials.gov) - Jan 29, 2013
P4, N=40, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Active, not recruiting --> Completed Initiation date: Dec 2011 --> Jan 2013
- Enrollment change: Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits (clinicaltrials.gov) - Jan 29, 2013
P=N/A, N=40, Completed, Sponsor: New York University School of Medicine
Initiation date: Dec 2011 --> Jan 2013 N=90 --> 40
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Enrollment open, Adverse events: XRNT: Depot Naltrexone Mechanism of Action in Heroin Dependent Patients Using fMRI and SPECT (clinicaltrials.gov) - Jan 29, 2013
P4, N=40, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
N=90 --> 40 Not yet recruiting --> Recruiting
- Trial completion: Impact of Exercise and Affirmations (IntenSati) on Addiction-related Cognitive and Psychosocial Deficits (clinicaltrials.gov) - Jan 29, 2013
P=N/A, N=40, Completed, Sponsor: New York University School of Medicine
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment change: fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults (clinicaltrials.gov) - Jan 28, 2013
P=N/A, N=29, Completed, Sponsor: Inova Health Care Services
Active, not recruiting --> Completed N=50 --> 29
- Trial completion: fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults (clinicaltrials.gov) - Jan 28, 2013
P=N/A, N=29, Completed, Sponsor: Inova Health Care Services
N=50 --> 29 Recruiting --> Completed