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67 Companies |
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95 Products |
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95 Products |
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124 Mechanisms of Action |
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1 Trial |
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1960 News |
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- | Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Trial completion, Trial primary completion date: CHOICES: Comparing Treatments for HIV-Infected Opioid and Alcohol Users in an Integrated Care Effectiveness Study (clinicaltrials.gov) - Apr 28, 2015
P3, N=51, Completed, Sponsor: Oregon Health and Science University
Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Mar 2015
- hydrocortisone / Generic mfg.
Trial primary completion date: Studies of Opioid Seeking Behavior: Yohimbine and Hydrocortisone Effects (clinicaltrials.gov) - Apr 23, 2015
P=N/A, N=16, Recruiting, Sponsor: Wayne State University
Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Mar 2015 Trial primary completion date: Jun 2015 --> Dec 2015
- acetylcysteine solution / Generic mfg.
Trial primary completion date: Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC) (clinicaltrials.gov) - Apr 23, 2015
P=N/A, N=15, Recruiting, Sponsor: Wayne State University
Trial primary completion date: Jun 2015 --> Dec 2015 Trial primary completion date: Jun 2015 --> Dec 2015
- ||| Enrollment open: Ambivalence Model of Craving: Re-examining the Drinking-craving Relationship (clinicaltrials.gov) - Apr 22, 2015
P=N/A, N=100, Recruiting, Sponsor: University of South Florida
Trial primary completion date: Jun 2015 --> Dec 2015 Not yet recruiting --> Recruiting
- Enrollment closed: AHCM: Addiction Housing Case Management for Homeless Veterans (clinicaltrials.gov) - Apr 22, 2015
P=N/A, N=400, Active, not recruiting, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- aspirin / Generic mfg.
Enrollment change: Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers (clinicaltrials.gov) - Apr 21, 2015
P2, N=56, Recruiting, Sponsor: National Cancer Institute (NCI)
Recruiting --> Active, not recruiting N=44 --> 56
- Enrollment change, Trial termination: CIRROX: Phlebotomy and Risk of Hepatocellular Carcinoma in Patients With Compensated Alcoholic Cirrhosis (clinicaltrials.gov) - Apr 21, 2015
P3, N=17, Terminated, Sponsor: Assistance Publique - H
N=44 --> 56 N=324 --> 17 | Suspended --> Terminated; delayed recruitment as compared to that expected
- naloxone injection / Generic mfg., remifentanil / Generic mfg.
Enrollment closed: Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (clinicaltrials.gov) - Apr 21, 2015
P1/2, N=12, Active, not recruiting, Sponsor: Norwegian University of Science and Technology
N=324 --> 17 | Suspended --> Terminated; delayed recruitment as compared to that expected Recruiting --> Active, not recruiting
- || Enrollment closed: SBIRT-PC: Screening, Brief Intervention, and Referral to Treatment in Primary Care (clinicaltrials.gov) - Apr 20, 2015
P=N/A, N=120, Active, not recruiting, Sponsor: Duke University
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- risperidone / Generic mfg., desipramine / Generic mfg.
Trial completion, Enrollment change: RADIAUS: Risperidone and Desipramine in Alcohol Use and Schizophrenia (clinicaltrials.gov) - Apr 20, 2015
P2, N=12, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | N=40 --> 12
- ||| Trial completion: Extinction01: Extinction Based Treatment for Nicotine Dependence (clinicaltrials.gov) - Apr 20, 2015
P1, N=257, Completed, Sponsor: Duke University
Active, not recruiting --> Completed | N=40 --> 12 Active, not recruiting --> Completed
- Trial primary completion date: Eye Movement Desensitization and Reprocessing (EMDR) in Alcohol Dependent Patients (clinicaltrials.gov) - Apr 19, 2015
P=N/A, N=100, Recruiting, Sponsor: IrisZorg
Active, not recruiting --> Completed Trial primary completion date: Jun 2015 --> Mar 2016
- Enrollment change, Trial withdrawal, Trial primary completion date: Traits Associated With Early Life Stress Among Treatment-Seeking Alcoholics (clinicaltrials.gov) - Apr 19, 2015
P=N/A, N=0, Withdrawn, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Trial primary completion date: Jun 2015 --> Mar 2016 N=120 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: May 2016 --> Mar 2015
- Trial primary completion date: OPAL: "Opiates and PhArmacoLogy" (clinicaltrials.gov) - Apr 18, 2015
P=N/A, N=354, Recruiting, Sponsor: Nantes University Hospital
N=120 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: May 2016 --> Mar 2015 Trial primary completion date: Jan 2015 --> Jun 2015
- Trial primary completion date: Individual vs. Group Community Reinforcement Training to Help Parents of Substance-using Treatment-refusing Youth (clinicaltrials.gov) - Apr 18, 2015
P=N/A, N=60, Recruiting, Sponsor: Oregon Research Institute
Trial primary completion date: Jan 2015 --> Jun 2015 Trial primary completion date: Oct 2014 --> Aug 2015
- || Ryzolt (abuse resistant formulation) / Endo
Trial primary completion date: Medications Development for Drug Abuse Disorders (clinicaltrials.gov) - Apr 18, 2015
P1/2, N=150, Recruiting, Sponsor: Johns Hopkins University
Trial primary completion date: Oct 2014 --> Aug 2015 Trial primary completion date: Jan 2015 --> Jul 2015
- Trial withdrawal: Effects of GSK598809 on Brain Activation in Abstinent Alcoholics (clinicaltrials.gov) - Apr 18, 2015
P1, N=0, Withdrawn, Sponsor: GlaxoSmithKline
Trial primary completion date: Jan 2015 --> Jul 2015 Terminated --> Withdrawn
- |||| Trial completion: ABT-436 for Alcohol Dependence (clinicaltrials.gov) - Apr 16, 2015
P2, N=148, Completed, Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Terminated --> Withdrawn Active, not recruiting --> Completed
- Enrollment change, Compliance: MAPIT: Motivational Assessment Program to Initiate Treatment (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=400, Recruiting, Sponsor: University of North Texas Health Science Center
Active, not recruiting --> Completed N=600 --> 400
- Enrollment change: cSBI-M for Young Military Personnel (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=0, Withdrawn, Sponsor: Children's Hospital Boston
N=600 --> 400 N=2500 --> 0
- Enrollment change: DAART+: Directly Administered Antiretroviral Therapy (DAART) Among HIV-1infected Injecting Drug Users (IDUs) in Chennai, India (clinicaltrials.gov) - Apr 15, 2015
P2/3, N=0, Withdrawn, Sponsor: Johns Hopkins University
N=2500 --> 0 N=100 --> 0
- Trial primary completion date: Integrated CBT for Cannabis Dependence With Co-occurring Anxiety Disorders (clinicaltrials.gov) - Apr 14, 2015
P1, N=72, Recruiting, Sponsor: Louisiana State University and A&M College
N=100 --> 0 Trial primary completion date: Jul 2015 --> Jul 2016
- Trial primary completion date: Progesterone & Postpartum Relapse to Smoking (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=36, Recruiting, Sponsor: University of Minnesota - Clinical and Translational Science Institute
Trial primary completion date: Jul 2015 --> Jul 2016 Trial primary completion date: Jun 2014 --> Jun 2015
- methadone / Generic mfg.
Trial primary completion date: Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=200, Recruiting, Sponsor: Assistance Publique - H
Trial primary completion date: Jun 2014 --> Jun 2015 Trial primary completion date: Dec 2014 --> May 2016
- Zyflo (zileuton) / Chiesi
Trial primary completion date: Zileuton With or Without Celecoxib As Chemopreventive Agents in Smokers (clinicaltrials.gov) - Apr 14, 2015
P1/2, N=84, Completed, Sponsor: National Cancer Institute (NCI)
Trial primary completion date: Dec 2014 --> May 2016 Trial primary completion date: Sep 2011 --> Aug 2012
- || Trial primary completion date, Surgery: Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer (clinicaltrials.gov) - Apr 14, 2015
P2, N=90, Active, not recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Sep 2011 --> Aug 2012 Trial primary completion date: Sep 2014 --> Sep 2015
- Trial primary completion date: Cognitive Retraining and Brain Stimulation for Alcohol Use (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=96, Recruiting, Sponsor: The Mind Research Network
Trial primary completion date: Sep 2014 --> Sep 2015 Trial primary completion date: Jun 2015 --> Dec 2015
- oxytocin / Generic mfg.
Trial primary completion date: Effect of Oxytocin on Craving and Therapy Response (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=40, Recruiting, Sponsor: Medical University of South Carolina
Trial primary completion date: Jun 2015 --> Dec 2015 Trial primary completion date: Dec 2014 --> Sep 2015
- Trial primary completion date: Efficacy of G-CSF in the Management of Steroid Non-responsive Severe Alcoholic Hepatitis (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=56, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Dec 2014 --> Sep 2015 Trial primary completion date: Mar 2015 --> Jun 2015
- |||| buprenorphine/naloxone sublingual film / Generic mfg.
Trial primary completion date: NTX-SBX: Naltrexone vs Buprenorphine-Naloxone for Opioid Dependence in Norway (clinicaltrials.gov) - Apr 14, 2015
P3, N=220, Recruiting, Sponsor: University of Oslo
Trial primary completion date: Mar 2015 --> Jun 2015 Trial primary completion date: Jan 2015 --> Sep 2015
- morphine sulphate / Generic mfg.
Trial primary completion date: Comparison of Buprenorphine to Morphine in Treatment of Neonatal Abstinence Syndrome (NAS) (clinicaltrials.gov) - Apr 14, 2015
P2, N=64, Enrolling by invitation, Sponsor: Mednax Center for Research, Education and Quality
Trial primary completion date: Jan 2015 --> Sep 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- naltrexone / Generic mfg.
Trial primary completion date: Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism (clinicaltrials.gov) - Apr 14, 2015
P4, N=160, Recruiting, Sponsor: Medical University of South Carolina
Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Jan 2015 --> Dec 2015
- isradipine / Generic mfg.
Trial primary completion date: Improving Buprenorphine Detoxification Outcomes With Isradipine (clinicaltrials.gov) - Apr 14, 2015
P1/2, N=60, Recruiting, Sponsor: University of Arkansas
Trial primary completion date: Jan 2015 --> Dec 2015 Trial primary completion date: Sep 2015 --> Dec 2015
- || Trial primary completion date: Study of Effectiveness of Adding the Health Promotion and Rehabilitation for Treatment for Alcohol and Drug Abusers (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=260, Active, not recruiting, Sponsor: Skane University Hospital
Trial primary completion date: Sep 2015 --> Dec 2015 Trial primary completion date: Mar 2015 --> Mar 2017
- | acetylcysteine solution / Generic mfg.
Enrollment closed, Trial primary completion date: ACCENT: Achieving Cannabis Cessation-Evaluating N-Acetylcysteine Treatment (clinicaltrials.gov) - Apr 13, 2015
P3, N=300, Active, not recruiting, Sponsor: Medical University of South Carolina
Trial primary completion date: Mar 2015 --> Mar 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jul 2015
- Enrollment closed, Trial primary completion date: Family-Based Treatment for Parental Substance Abuse and Child Maltreatment (clinicaltrials.gov) - Apr 13, 2015
P=N/A, N=240, Active, not recruiting, Sponsor: Medical University of South Carolina
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jul 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jan 2015 --> Apr 2016
- Trial completion, Trial primary completion date: Research on Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders (clinicaltrials.gov) - Apr 13, 2015
P2, N=140, Completed, Sponsor: Medical University of South Carolina
Recruiting --> Active, not recruiting | Trial primary completion date: Jan 2015 --> Apr 2016 Active, not recruiting --> Completed | Trial primary completion date: Jun 2013 --> Jun 2014
- Trial completion: Outpatient Adolescent Treatment for Comorbid Substance Use and Internalizing Disorders (clinicaltrials.gov) - Apr 13, 2015
P1, N=40, Completed, Sponsor: Medical University of South Carolina
Active, not recruiting --> Completed | Trial primary completion date: Jun 2013 --> Jun 2014 Active, not recruiting --> Completed
- | NN1213 / Novo Nordisk
Trial completion: Comparison of HIV Clinic-based Treatment With Buprenorphine Versus Referred Care in Heroin-dependent Participants (clinicaltrials.gov) - Apr 13, 2015
P2, N=120, Completed, Sponsor: Johns Hopkins University
Active, not recruiting --> Completed Active, not recruiting --> Completed
- || Biomarker: MAW Phase 2: Biomarker Feedback to Motivate Tobacco Cessation in Pregnant ALaska Native Women: Phase 2 (clinicaltrials.gov) - Apr 10, 2015
P=N/A, N=64, Active, not recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Dec 2015
- zonisamide / Generic mfg., levetiracetam / Generic mfg., topiramate / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism (clinicaltrials.gov) - Apr 7, 2015
P2, N=85, Terminated, Sponsor: Boston Medical Center
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Dec 2015 N=160 --> 85 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2014 --> Aug 2013; Recruitment goals could not be met before ending of funding for this project.
- Enrollment closed: Development and Testing of Adolescent Twelve-Step Facilitation (clinicaltrials.gov) - Apr 7, 2015
P=N/A, N=60, Active, not recruiting, Sponsor: Massachusetts General Hospital
N=160 --> 85 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2014 --> Aug 2013; Recruitment goals could not be met before ending of funding for this project. Recruiting --> Active, not recruiting
- | NN1213 / Novo Nordisk
Trial completion: Substance Abuse Self-Help Group Referral: Outcomes and Services Use (clinicaltrials.gov) - Apr 5, 2015
P=N/A, N=345, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Active, not recruiting No longer recruiting --> Completed
- ||| Enrollment closed, Enrollment change: ProjectSTART: Screening to Augment Referral to Treatment- Project START (clinicaltrials.gov) - Apr 3, 2015
P2, N=495, Active, not recruiting, Sponsor: Yale University
No longer recruiting --> Completed Recruiting --> Active, not recruiting | N=660 --> 495
- Enrollment change, Compliance: Compliance Monitoring in Real Time During Opioid Substitution Treatment (clinicaltrials.gov) - Apr 1, 2015
P=N/A, N=0, Withdrawn, Sponsor: Kuopio University Hospital
Recruiting --> Active, not recruiting | N=660 --> 495 N=15 --> 0
- || Enrollment closed, Trial primary completion date, Adherence: COPE: Contingency Outcomes in Prolonged Exposure (clinicaltrials.gov) - Apr 1, 2015
P=N/A, N=125, Active, not recruiting, Sponsor: Johns Hopkins University
N=15 --> 0 Enrolling by invitation --> Active, not recruiting | Trial primary completion date: Dec 2014 --> May 2015
- | Lucemyra (lofexidine) / US WorldMeds, Stada
Trial completion: D-LUCS: Combined Pharmacotherapy for Cannabis Dependency (clinicaltrials.gov) - Apr 1, 2015
P2/3, N=156, Completed, Sponsor: New York State Psychiatric Institute
Enrolling by invitation --> Active, not recruiting | Trial primary completion date: Dec 2014 --> May 2015 Recruiting --> Completed
- divalproex sodium XR / Generic mfg.
Enrollment change: Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence (clinicaltrials.gov) - Mar 31, 2015
P2, N=0, Withdrawn, Sponsor: The University of Texas, Galveston
Recruiting --> Completed N=30 --> 0
- Intuniv (guanfacine XR) / Shionogi, Takeda
Trial completion, Trial primary completion date: Open-Label Pilot Study of Guanfacine-Extended Release for the Treatment of Cannabis Dependence (clinicaltrials.gov) - Mar 31, 2015
P1, N=22, Completed, Sponsor: New York State Psychiatric Institute
N=30 --> 0 Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Mar 2015
- | NN1213 / Novo Nordisk
Trial completion: HIV Counseling Intervention for Methadone-Maintained Patients - 2 (clinicaltrials.gov) - Mar 30, 2015
P1, N=50, Completed, Sponsor: New York State Psychiatric Institute
Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Mar 2015 No longer recruiting --> Completed