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70 Companies |
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97 Products |
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97 Products |
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124 Mechanisms of Action |
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1 Trial |
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1962 News |
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- Enrollment change, Trial termination, Head-to-Head: FoBeMA: Internet-Based Relapse Prevention vs Face to Face Therapy at an Employee Assistance Program (clinicaltrials.gov) - Mar 15, 2016
P=N/A, N=1, Terminated, Sponsor: Karolinska Institutet
N=90 --> 1 | Recruiting --> Terminated; Only 1 participant recruited to study. Qs addressed in other ongoing studies.
- Enrollment closed, Trial primary completion date: Supportive Text Messages to Reduce Mood Symptoms and Problem Drinking- Randomised Controlled Pilot Trials (clinicaltrials.gov) - Mar 15, 2016
P=N/A, N=131, Active, not recruiting, Sponsor: University of Alberta
Qs addressed in other ongoing studies. Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016
- prazosin / Generic mfg.
Enrollment change, Trial termination: Prazosin for ETOH or Cocaine Craving (clinicaltrials.gov) - Mar 14, 2016
P=N/A, N=8, Terminated, Sponsor: VA Office of Research and Development
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Aug 2016 N=32 --> 8 | Completed --> Terminated; Experimental procedure did not induce sufficient craving to determine any possible effect of medication.
- gemfibrozil / Generic mfg.
Trial completion, Enrollment change: Initial Screening of Gemfibrozil as a Novel Treatment for Tobacco Addiction (clinicaltrials.gov) - Mar 11, 2016
P2, N=27, Completed, Sponsor: Centre for Addiction and Mental Health
N=32 --> 8 | Completed --> Terminated; Experimental procedure did not induce sufficient craving to determine any possible effect of medication. Recruiting --> Completed | N=40 --> 27
- Trial primary completion date: SF-FASD: Parenting Training for Children With FASD (clinicaltrials.gov) - Mar 9, 2016
P=N/A, N=200, Recruiting, Sponsor: IWK Health Centre
Recruiting --> Completed | N=40 --> 27 Trial primary completion date: Jan 2016 --> Jul 2016
- | buprenorphine/naloxone sublingual film / Generic mfg.
Enrollment closed, Enrollment change, Trial primary completion date: NTX-SBX: Naltrexone vs Buprenorphine-Naloxone for Opioid Dependence in Norway (clinicaltrials.gov) - Mar 9, 2016
P3, N=166, Active, not recruiting, Sponsor: University of Oslo
Trial primary completion date: Jan 2016 --> Jul 2016 Recruiting --> Active, not recruiting | N=220 --> 166 | Trial primary completion date: Sep 2015 --> May 2016
- Trial completion: Understanding Drug Abuse Treatment Outcomes (clinicaltrials.gov) - Mar 9, 2016
P=N/A, N=18, Completed, Sponsor: National Institute on Drug Abuse (NIDA)
Recruiting --> Active, not recruiting | N=220 --> 166 | Trial primary completion date: Sep 2015 --> May 2016 Recruiting --> Completed
- Vivitrol (naltrexone extended-release injectable suspension) / Alkermes
Trial completion, Enrollment change, Trial primary completion date: INSPIRE: Alcohol Pharmacotherapy for HIV+ Prisoners (clinicaltrials.gov) - Mar 8, 2016
P=N/A, N=100, Completed, Sponsor: Yale University
Recruiting --> Completed Active, not recruiting --> Completed | N=125 --> 100 | Trial primary completion date: Aug 2016 --> Aug 2015
- Trial completion: Transforming Opioid Prescribing in Primary Care (clinicaltrials.gov) - Mar 4, 2016
P=N/A, N=53, Completed, Sponsor: Boston Medical Center
Active, not recruiting --> Completed | N=125 --> 100 | Trial primary completion date: Aug 2016 --> Aug 2015 Active, not recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: Enhancing Early-Phase Care for Primary Care Patients With Unhealthy Substance Use (clinicaltrials.gov) - Mar 4, 2016
P=N/A, N=13, Completed, Sponsor: Brandeis University
Active, not recruiting --> Completed Recruiting --> Completed | N=120 --> 13 | Trial primary completion date: Jul 2014 --> Dec 2015
- midazolam hydrochloride / Generic mfg.
Enrollment change, Trial withdrawal, Trial primary completion date: Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam (clinicaltrials.gov) - Mar 1, 2016
P4, N=0, Withdrawn, Sponsor: Virginia Commonwealth University
Recruiting --> Completed | N=120 --> 13 | Trial primary completion date: Jul 2014 --> Dec 2015 N=10 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jul 2012 --> Mar 2009
- | NN1213 / Novo Nordisk
Trial completion: Multimodal Treatment Study of Children With Attention Deficit and Hyperactivity Disorder (MTA) (clinicaltrials.gov) - Feb 27, 2016
P4, N=0, Completed, Sponsor: New York University School of Medicine
N=10 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jul 2012 --> Mar 2009 No longer recruiting --> Completed
- | NN1213 / Novo Nordisk
Enrollment change: Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women (clinicaltrials.gov) - Feb 27, 2016
P3, N=387, Completed, Sponsor: Johns Hopkins University
No longer recruiting --> Completed N=300 --> 387
- Enrollment change: VIGICANN: Study of the Relationship Between Dose-concentration-effect of Delta-9-tetrahydrocannabinol (THC) and the Ability to Drive in Chronic or Occasional Cannabis Users (clinicaltrials.gov) - Feb 24, 2016
P=N/A, N=37, Active, not recruiting, Sponsor: Assistance Publique - H
N=300 --> 387 N=30 --> 37
- Enrollment change: Helping Families Help Veterans With PTSD and Alcohol Abuse: An RCT of VA-CRAFT (clinicaltrials.gov) - Feb 24, 2016
P=N/A, N=66, Active, not recruiting, Sponsor: VA Office of Research and Development
N=30 --> 37 N=336 --> 66
- | Trial completion, Trial primary completion date: Vigabatrin for the Treatment of Cocaine Dependency (clinicaltrials.gov) - Feb 23, 2016
P2/3, N=207, Completed, Sponsor: Catalyst Pharmaceuticals, Inc.
N=336 --> 66 Active, not recruiting --> Completed | Trial primary completion date: Jul 2012 --> Oct 2012
- citalopram / Generic mfg.
Trial completion, Enrollment change: Brain Function and Structure in Cocaine Dependence (clinicaltrials.gov) - Feb 22, 2016
P2, N=28, Completed, Sponsor: Virginia Commonwealth University
Active, not recruiting --> Completed | Trial primary completion date: Jul 2012 --> Oct 2012 Recruiting --> Completed | N=56 --> 28
- Trial completion, Enrollment change: WAAICUP: Opioids Withdrawal Syndrome in Critically Ill Patients: a Multicenter Prospective Cohort Study (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=54, Completed, Sponsor: Hopital du Sacre-Coeur de Montreal
Recruiting --> Completed | N=56 --> 28 Not yet recruiting --> Completed | N=100 --> 54
- Trial completion: Preventing FAS/ARND in Russian Children (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=767, Completed, Sponsor: University of Oklahoma
Not yet recruiting --> Completed | N=100 --> 54 Active, not recruiting --> Completed
- topiramate / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Topiramate to Reduce Heavy Drinking in HIV-Positive Heavy Drinkers (clinicaltrials.gov) - Feb 17, 2016
P2, N=4, Terminated, Sponsor: University of Pennsylvania
Active, not recruiting --> Completed N=60 --> 4 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Jan 2014; We terminated the study due to problems recruiting alcoholic subjects with HIV.
- Enrollment closed, Enrollment change: Safety and Health Intervention Project (clinicaltrials.gov) - Feb 17, 2016
P=N/A, N=139, Active, not recruiting, Sponsor: University of Michigan
N=60 --> 4 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Jan 2014; We terminated the study due to problems recruiting alcoholic subjects with HIV. Recruiting --> Active, not recruiting | N=400 --> 139
- Ryzolt (abuse resistant formulation) / Endo
Enrollment closed, Trial primary completion date: Medications Development for Drug Abuse Disorders (clinicaltrials.gov) - Feb 17, 2016
P1/2, N=150, Active, not recruiting, Sponsor: Johns Hopkins University
Recruiting --> Active, not recruiting | N=400 --> 139 Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2015 --> Dec 2015
- |||| Selincro (nalmefene oral) / Lundbeck, Acorda
Trial completion, Enrollment change: Study of 18 mg Selincro (clinicaltrials.gov) - Feb 17, 2016
P4, N=378, Completed, Sponsor: H. Lundbeck A/S
Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2015 --> Dec 2015 Active, not recruiting --> Completed | N=635 --> 378
- Trial primary completion date: Effect of Anti-craving Medication on Cognitive Functions in Alcohol Dependence: an ERP Study (clinicaltrials.gov) - Feb 12, 2016
P=N/A, N=80, Recruiting, Sponsor: Brugmann University Hospital
Active, not recruiting --> Completed | N=635 --> 378 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial primary completion date: VIGICANN: Study of the Relationship Between Dose-concentration-effect of Delta-9-tetrahydrocannabinol (THC) and the Ability to Drive in Chronic or Occasional Cannabis Users (clinicaltrials.gov) - Feb 11, 2016
P=N/A, N=30, Active, not recruiting, Sponsor: Assistance Publique - H
Trial primary completion date: Dec 2015 --> Dec 2016 Trial primary completion date: Nov 2015 --> Jul 2015
- Trial completion, Enrollment change, Trial primary completion date: Long Term Effect of Aggressive Nutritional Management on Survival in Patients With Alcoholic Liver Disease (clinicaltrials.gov) - Feb 11, 2016
P=N/A, N=147, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Trial primary completion date: Nov 2015 --> Jul 2015 Recruiting --> Completed | N=856 --> 147 | Trial primary completion date: May 2016 --> Dec 2015
- ondansetron / Generic mfg., morphine sulphate / Generic mfg.
Enrollment closed, Enrollment change, Trial primary completion date: 5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence (clinicaltrials.gov) - Feb 10, 2016
P=N/A, N=76, Active, not recruiting, Sponsor: Stanford University
Recruiting --> Completed | N=856 --> 147 | Trial primary completion date: May 2016 --> Dec 2015 Recruiting --> Active, not recruiting | N=133 --> 76 | Trial primary completion date: Apr 2014 --> Apr 2015
- lorazepam / Generic mfg., dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD) (clinicaltrials.gov) - Feb 9, 2016
P4, N=49, Terminated, Sponsor: Denver Health and Hospital Authority
Recruiting --> Active, not recruiting | N=133 --> 76 | Trial primary completion date: Apr 2014 --> Apr 2015 N=150 --> 49 | Recruiting --> Terminated; DSMB recommendation for slow enrollment
- Buprenex (buprenorphine) / Reckitt Benckiser
Trial primary completion date: MOPPlus: Buprenorphine for Treatment of Neonatal Abstinence Syndrome in Infants With In Utero Exposure to Benzodiazepines (clinicaltrials.gov) - Feb 5, 2016
P1, N=40, Recruiting, Sponsor: Thomas Jefferson University
N=150 --> 49 | Recruiting --> Terminated; DSMB recommendation for slow enrollment Trial primary completion date: Dec 2015 --> Dec 2016
- Enrollment closed, Enrollment change: RAFIKI: A Stage 2 Cognitive-behavioral Trial: Reduce Alcohol First in Kenya Intervention (clinicaltrials.gov) - Feb 2, 2016
P1, N=614, Active, not recruiting, Sponsor: Brown University
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Active, not recruiting | N=336 --> 614
- Trial completion, Enrollment change: An Exercise App to Reduce Young Adults' MJ Use (clinicaltrials.gov) - Feb 2, 2016
P=N/A, N=36, Completed, Sponsor: State University of New York at Buffalo
Recruiting --> Active, not recruiting | N=336 --> 614 Recruiting --> Completed | N=52 --> 36
- Trial primary completion date: Indocyanine Green and Portal Pressure in Viral and Alcoholic Cirrhotic Patients With Hepatocarcinoma (clinicaltrials.gov) - Jan 28, 2016
P=N/A, N=60, Recruiting, Sponsor: University of Lausanne Hospitals
Recruiting --> Completed | N=52 --> 36 Trial primary completion date: Feb 2014 --> Jun 2016
- Trial completion, MRI: Endophenotyping With Functional Magnetic Resonance Imaging (fMRI) (clinicaltrials.gov) - Jan 28, 2016
P=N/A, N=480, Completed, Sponsor: Charite University, Berlin, Germany
Trial primary completion date: Feb 2014 --> Jun 2016 Recruiting --> Completed
- acetylcysteine solution / Generic mfg.
Trial primary completion date: Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC) (clinicaltrials.gov) - Jan 26, 2016
P=N/A, N=15, Recruiting, Sponsor: Wayne State University
Recruiting --> Completed Trial primary completion date: Dec 2015 --> Jul 2016
- Trial completion, Enrollment change, Trial primary completion date: Evaluating Three Methods for Helping Syringe Exchangers Begin Methadone Maintenance (clinicaltrials.gov) - Jan 25, 2016
P=N/A, N=223, Completed, Sponsor: Johns Hopkins University
Trial primary completion date: Dec 2015 --> Jul 2016 Active, not recruiting --> Completed | N=520 --> 223 | Trial primary completion date: Jan 2016 --> Oct 2015
- Enrollment change, Trial termination, Trial primary completion date: Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD (clinicaltrials.gov) - Jan 25, 2016
P=N/A, N=19, Terminated, Sponsor: VA Office of Research and Development
Active, not recruiting --> Completed | N=520 --> 223 | Trial primary completion date: Jan 2016 --> Oct 2015 N=150 --> 19 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Jan 2016; PI moving outside VA- grant not transferable
- Trial completion: Prospective Assessment of Adolescent Drinking Trajectories With Computer-Assisted Self-administration of Ethanol (CASE) (clinicaltrials.gov) - Jan 21, 2016
P=N/A, N=96, Completed, Sponsor: Technische Universit
N=150 --> 19 | Recruiting --> Terminated | Trial primary completion date: Mar 2018 --> Jan 2016; PI moving outside VA- grant not transferable Active, not recruiting --> Completed
- | Selincro (nalmefene oral) / Lundbeck, Acorda
Trial completion, Enrollment change: Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro (clinicaltrials.gov) - Jan 20, 2016
P4, N=45, Completed, Sponsor: H. Lundbeck A/S
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=60 --> 45
- |||||| Enrollment open, Trial primary completion date: Pro-Change Smoking Cessation Intervention (clinicaltrials.gov) - Jan 19, 2016
P2/3, N=438, Recruiting, Sponsor: VAL Health, LLC
Active, not recruiting --> Completed | N=60 --> 45 Not yet recruiting --> Recruiting | Trial primary completion date: Jul 2015 --> Aug 2016
- aspirin / Generic mfg.
Trial primary completion date: Intermittent or Continuous Acetylsalicylic Acid and Gene Expression in the Nasal Tissue of Current Smokers (clinicaltrials.gov) - Jan 17, 2016
P2, N=56, Recruiting, Sponsor: National Cancer Institute (NCI)
Not yet recruiting --> Recruiting | Trial primary completion date: Jul 2015 --> Aug 2016 Trial primary completion date: Jan 2016 --> Jul 2016
- Trial primary completion date, Surgery: Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer (clinicaltrials.gov) - Jan 17, 2016
P2, N=90, Active, not recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Jan 2016 --> Jul 2016 Trial primary completion date: Sep 2015 --> Sep 2016
- Biomarker: Biomarker Feedback to Motivate Tobacco Cessation in Pregnant Alaska Native Women (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=150, Active, not recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Sep 2015 --> Sep 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jun 2016
- | Biomarker, Trial completion: MAW Phase 2: Biomarker Feedback to Motivate Tobacco Cessation in Pregnant ALaska Native Women: Phase 2 (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=39, Completed, Sponsor: Mayo Clinic
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2015 --> Jun 2016 Active, not recruiting --> Completed | N=64 --> 39 | Trial primary completion date: Dec 2015 --> Aug 2015 | Active, not recruiting --> Completed
- Trial completion, Enrollment change: Expansion to Interdisciplinary HIV Prevention in Women (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=41, Completed, Sponsor: University of Oklahoma
Active, not recruiting --> Completed | N=64 --> 39 | Trial primary completion date: Dec 2015 --> Aug 2015 | Active, not recruiting --> Completed Active, not recruiting --> Completed | N=100 --> 41
- ||| diazepam / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Clinical Quality Improvement of Benzodiazepine-Resistant Alcohol Withdrawal Syndrome (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=792, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | N=100 --> 41 Active, not recruiting --> Completed | N=1000 --> 792 | Trial primary completion date: Jul 2014 --> Sep 2015
- Trial completion: Helping Hospitalized Patients Quit Smoking (clinicaltrials.gov) - Jan 11, 2016
P4, N=600, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed | N=1000 --> 792 | Trial primary completion date: Jul 2014 --> Sep 2015 Active, not recruiting --> Completed
- zonisamide / Generic mfg.
Enrollment change, Trial termination: Zonisamide for Heavy Drinkers With Bipolar Disorder (clinicaltrials.gov) - Jan 7, 2016
P2, N=3, Terminated, Sponsor: VA Connecticut Healthcare System
Active, not recruiting --> Completed N=40 --> 3 | Recruiting --> Terminated; recruitment infeasible
- | naltrexone / Generic mfg.
Trial completion: Adaptive Treatment for Alcohol and Cocaine Dependence (clinicaltrials.gov) - Jan 7, 2016
P2/3, N=300, Completed, Sponsor: University of Pennsylvania
N=40 --> 3 | Recruiting --> Terminated; recruitment infeasible Active, not recruiting --> Completed
- Enrollment closed: Component Analysis for Motivational Interviewing (clinicaltrials.gov) - Dec 31, 2015
P=N/A, N=210, Active, not recruiting, Sponsor: North Shore Long Island Jewish Health System
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ropinirole IR / Generic mfg.
Trial primary completion date: Cognitive Remediation for Cocaine Dependence (clinicaltrials.gov) - Dec 29, 2015
P2, N=200, Recruiting, Sponsor: The University of Texas Health Science Center, Houston
Recruiting --> Active, not recruiting Trial primary completion date: May 2015 --> Dec 2016