Spinal Cord Injuries News - LARVOL Sigma

Spinal Cord Injuries

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37 Mechanisms of Action

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|||||||||| Trial completion: Multifaceted Treatment of Catheter-related Urinary Tract Infection (clinicaltrials.gov) - Apr 14, 2013
P2, N=75, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed

|||||||||| Trial completion, HEOR, Cost effectiveness, Metastases: MESCC: Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression (clinicaltrials.gov) - Apr 10, 2013
P4, N=432, Completed, Sponsor: AO Clinical Investigation and Documentation
Recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Effects of Vaporized Marijuana on Neuropathic Pain (clinicaltrials.gov) - Apr 4, 2013
P1/2, N=44, Completed, Sponsor: University of California, Davis
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: Comparative Study of the Efficacy and Safety of Muscarinic M3 Receptors Antagonists in the Treatment of Neurogenic Detrusor Overactivity (clinicaltrials.gov) - Apr 3, 2013
P4, N=23, Completed, Sponsor: Toronto Rehabilitation Institute
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  midodrine hydrochloride / Generic mfg.
New P4 trial:  Body Temperature in Persons With Tetraplegia When Exposed to Cold (clinicaltrials.gov) -  Mar 31, 2013
P4, N=30, Recruiting,  Sponsor: James J. Peters Veterans Affairs Medical Center

|||||||||| Clinical: Follow up Study of Diaphragm Pacing for Patients With High Tetraplegia (clinicaltrials.gov) - Mar 19, 2013
P=N/A, N=60, Recruiting, Sponsor: Craig Hospital

|||||||||| Trial completion: Diaphragmatic Pacemaker in Tetraplegic Patients With Spinal Cord Injuries (clinicaltrials.gov) - Mar 17, 2013
P=N/A, N=5, Completed, Sponsor: University of Sao Paulo
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Minocycline and Perfusion Pressure Augmentation in Acute Spinal Cord Injury (clinicaltrials.gov) - Mar 14, 2013
P1/2, N=52, Completed, Sponsor: University of Calgary
Recruiting --> Completed Recruiting --> Completed

||||||||||  V158866 / Neuritek Therap
Enrollment open:  A Safety, Tolerability and Efficacy Study of V158866 in Central Neuropathic Pain Following Spinal Cord Injury (clinicaltrials.gov) -  Mar 7, 2013
P2a, N=36, Recruiting,  Sponsor: Brigham and Women's Hospital
Recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| Trial completion: TDS-1: Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis (clinicaltrials.gov) - Mar 6, 2013
P1, N=61, Completed, Sponsor: Georgia Institute of Technology
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| HEOR, Cost effectiveness: ESCALE: Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients (clinicaltrials.gov) - Feb 28, 2013
P=N/A, N=742, Recruiting, Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

||||||||||  zoledronic acid / Generic mfg.
New P3 trial:  Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol) (clinicaltrials.gov) -  Feb 27, 2013
P3, N=100, Recruiting,  Sponsor: Nantes University Hospital

||||||||||  testosterone gel / Generic mfg.
Trial completion:  Testosterone Replacement Therapy in Chronic Spinal Cord Injury (clinicaltrials.gov) -  Feb 26, 2013
P2/3, N=31, Completed,  Sponsor: Department of Veterans Affairs
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Clinical: Power Over Pain (POP) Study (clinicaltrials.gov) - Feb 25, 2013
P=N/A, N=144, Recruiting, Sponsor: University of Washington

|||||||||| Trial completion: Colonizing Neurogenic Bladders With Benign Flora (clinicaltrials.gov) - Feb 20, 2013
P1, N=20, Completed, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Aldurazyme (laronidase) / BioMarin, Sanofi
Enrollment change:  Intrathecal Enzyme Replacement Therapy for Spinal Cord Compression in Mucopolysaccharidosis (MPS) I (clinicaltrials.gov) -  Feb 19, 2013
P1, N=4, Terminated,  Sponsor: Patricia I. Dickson, M.D.
Recruiting --> Completed N=10 --> 4

||||||||||  Aldurazyme (laronidase) / BioMarin, Sanofi
Enrollment change:  Extension Study of Intrathecal Enzyme Replacement Therapy for MPS I (clinicaltrials.gov) -  Feb 18, 2013
P1, N=3, Terminated,  Sponsor: Patricia I. Dickson, M.D.
N=10 --> 4 N=10 --> 3

|||||||||| Trial termination: Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury (clinicaltrials.gov) - Feb 11, 2013
P2, N=19, Terminated, Sponsor: Healthpoint
N=10 --> 3 Recruiting --> Terminated; Business decision

|||||||||| Enrollment change: Comparison of HP011-101 to Standard Care for Stage I-II Pressure Ulcers in Subjects With Spinal Cord Injury (clinicaltrials.gov) - Feb 11, 2013
P2, N=19, Terminated, Sponsor: Healthpoint
Recruiting --> Terminated; Business decision N=40 --> 19

|||||||||| Enrollment change: Role of Residual Urine and Asymptomatic Prostatitis in the Development of Urinary Tract Infections in Spinal Cord Injury (clinicaltrials.gov) - Feb 10, 2013
P=N/A, N=60, Completed, Sponsor: Swiss Paraplegic Centre Nottwil
N=40 --> 19 N=80 --> 60

|||||||||| Trial completion: Role of Residual Urine and Asymptomatic Prostatitis in the Development of Urinary Tract Infections in Spinal Cord Injury (clinicaltrials.gov) - Feb 10, 2013
P=N/A, N=60, Completed, Sponsor: Swiss Paraplegic Centre Nottwil
N=80 --> 60 Recruiting --> Completed

|||||||||| New P2 trial: The Effects of Transcranial Direct Current Stimulation on Central Pain in Patients With Spinal Cord Injury (clinicaltrials.gov) - Jan 29, 2013
P2, N=16, Completed, Sponsor: Seoul National University Bundang Hospital

|||||||||| Trial completion: Biomechanics of Wheelchair Transfers (clinicaltrials.gov) - Jan 27, 2013
P=N/A, N=5, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment open: Multimodal Exercises to Improve Leg Function After Spinal Cord Injury (clinicaltrials.gov) - Jan 22, 2013
P=N/A, N=75, Recruiting, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| New P1 trial: Safety Study of Human Spinal Cord-derived Neural Stem Cell Transplantation for the Treatment of Chronic SCI (clinicaltrials.gov) - Jan 17, 2013
P1, N=8, Not yet recruiting, Sponsor: Neuralstem Inc.

|||||||||| Trial completion: Measuring Signatures in the Fluid Surrounding the Spinal Cord in Patients Who Have Problems With Intrathecal Drug Delivery (clinicaltrials.gov) - Jan 16, 2013
P=N/A, N=47, Completed, Sponsor: MedtronicNeuro
Not yet recruiting --> Recruiting Active, not recruiting --> Completed

|||||||||| New P1 trial: Tissue Bonding Cystostomy(TBC) (clinicaltrials.gov) - Jan 16, 2013
P1, N=10, Not yet recruiting, Sponsor: Uro-Research, LLC

|||||||||| New P1/2 trial: Safety and Effect of Adipose Tissue Derived Mesenchymal Stem Cell Implantation in Patients With Spinal Cord Injury (clinicaltrials.gov) - Jan 15, 2013
P1/2, N=15, Recruiting, Sponsor: K-Stemcell Co Ltd

|||||||||| Metastases: Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction (clinicaltrials.gov) - Jan 14, 2013
P=N/A, N=96, Recruiting, Sponsor: University of Zurich

|||||||||| Enrollment change: Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury (clinicaltrials.gov) - Jan 13, 2013
P2, N=120, Completed, Sponsor: Kessler Foundation
Active, not recruiting --> Completed N=160 --> 120

|||||||||| Trial completion: Preventing Pneumonia and Other Respiratory Problems in Persons With Spinal Cord Injury (clinicaltrials.gov) - Jan 13, 2013
P2, N=120, Completed, Sponsor: Kessler Foundation
N=160 --> 120 Active, not recruiting --> Completed

|||||||||| Trial completion: Platelet-Rich Plasma Therapy for Shoulder Pain in Persons With Spinal Cord Injury (clinicaltrials.gov) - Jan 13, 2013
P1, N=6, Completed, Sponsor: Kessler Foundation
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: SCILink: Scheduled Telephone Intervention for Individuals With Spinal Cord Injury and Their Families (clinicaltrials.gov) - Jan 9, 2013
P=N/A, N=168, Completed, Sponsor: Jeanne Hoffman
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment change: Incidence of Urinary Tract Infection After Urodynamic Investigation (clinicaltrials.gov) - Jan 6, 2013
P=N/A, N=317, Completed, Sponsor: Balgrist University Hospital
Active, not recruiting --> Completed N=250 --> 317

|||||||||| Trial completion: Incidence of Urinary Tract Infection After Urodynamic Investigation (clinicaltrials.gov) - Jan 6, 2013
P=N/A, N=317, Completed, Sponsor: Balgrist University Hospital
N=250 --> 317 Recruiting --> Completed

|||||||||| Trial completion: Restoring Walking in Non-ambulatory Children With Severe Chronic Spinal Cord Injury (SCI) (Kids STEP Study) (clinicaltrials.gov) - Jan 6, 2013
P1, N=7, Completed, Sponsor: University of Florida
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  dalfampridine / Generic mfg.
Enrollment open, Combination therapy:  Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury (clinicaltrials.gov) -  Dec 26, 2012
P2, N=46, Recruiting,  Sponsor: Kessler Foundation
Active, not recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| New P2 trial: AC105 in Patients With Acute Traumatic Spinal Cord Injury (clinicaltrials.gov) - Dec 13, 2012
P2, N=40, Enrolling by invitation, Sponsor: Acorda Therapeutics

||||||||||  V158866 / Neuritek Therap
New P2a trial:  A Safety, Tolerability and Efficacy Study of V158866 in Central Neuropathic Pain Following Spinal Cord Injury (clinicaltrials.gov) -  Dec 10, 2012
P2a, N=36, Recruiting,  Sponsor: Brigham and Women's Hospital

|||||||||| Enrollment change: Effects of Exercise in People With Tetraplegia (clinicaltrials.gov) - Dec 9, 2012
P=N/A, N=18, Completed, Sponsor: University of Miami
Not yet recruiting --> Recruiting N=24 --> 18

|||||||||| Trial completion: Effects of Exercise in People With Tetraplegia (clinicaltrials.gov) - Dec 9, 2012
P=N/A, N=18, Completed, Sponsor: University of Miami
N=24 --> 18 Recruiting --> Completed

||||||||||  zolmitriptan / Generic mfg.
Trial completion:  Effects of Zolmitriptan on Sensory Transmission After Spinal Cord Injury (clinicaltrials.gov) -  Nov 29, 2012
P=N/A, N=13, Completed,  Sponsor: University of Alberta
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Clinical: Hypothermia Following Acute Spinal Cord Injury (clinicaltrials.gov) - Nov 28, 2012
P=N/A, N=100, Recruiting, Sponsor: University of Miami

|||||||||| New P1 trial: Safety of Autologous Human Schwann Cells (ahSC) in Subjects With Subacute SCI (clinicaltrials.gov) - Nov 28, 2012
P1, N=8, Recruiting, Sponsor: University of Miami

|||||||||| Enrollment open: Vaporized Cannabis and Spinal Cord Injury Pain (clinicaltrials.gov) - Nov 27, 2012
P2/3, N=52, Recruiting, Sponsor: Barth Wilsey
Active, not recruiting --> Completed Not yet recruiting --> Recruiting

||||||||||  venlafaxine extended release / Generic mfg.
Enrollment change:  PRISMS: Project to Improve Symptoms and Mood in People With Spinal Cord Injury (clinicaltrials.gov) -  Nov 26, 2012
P4, N=133, Completed,  Sponsor: University of Washington
Not yet recruiting --> Recruiting N=168 --> 133

||||||||||  venlafaxine extended release / Generic mfg.
Trial completion:  PRISMS: Project to Improve Symptoms and Mood in People With Spinal Cord Injury (clinicaltrials.gov) -  Nov 26, 2012
P4, N=133, Completed,  Sponsor: University of Washington
N=168 --> 133 Recruiting --> Completed

||||||||||  chlorpromazine / Generic mfg.
Trial completion:  Cyproheptadine and Chlorpromazine Effects on Spasticity (clinicaltrials.gov) -  Nov 15, 2012
P=N/A, N=20, Completed,  Sponsor: University of Alberta
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment change: Chronic Pain and Brain Activity in Spinal Cord Injury (clinicaltrials.gov) - Nov 13, 2012
P=N/A, N=36, Completed, Sponsor: University of Washington
Active, not recruiting --> Completed N=50 --> 36

|||||||||| Trial completion: Chronic Pain and Brain Activity in Spinal Cord Injury (clinicaltrials.gov) - Nov 13, 2012
P=N/A, N=36, Completed, Sponsor: University of Washington
N=50 --> 36 Active, not recruiting --> Completed