Spinal Cord Injuries News - LARVOL Sigma

Spinal Cord Injuries

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37 Mechanisms of Action

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|||||||||| Trial initiation date: Comparing Surgical Decompression Versus Conservative Treatment in Incomplete Spinal Cord Injury (clinicaltrials.gov) - Nov 17, 2013
P=N/A, N=72, Recruiting, Sponsor: Radboud University
Initiation date: Jan 2012 --> Oct 2013

|||||||||| Enrollment open: Comparing Surgical Decompression Versus Conservative Treatment in Incomplete Spinal Cord Injury (clinicaltrials.gov) - Nov 17, 2013
P=N/A, N=72, Recruiting, Sponsor: Radboud University
Initiation date: Jan 2012 --> Oct 2013 Not yet recruiting --> Recruiting

|||||||||| Trial completion: Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading. (clinicaltrials.gov) - Oct 30, 2013
P=N/A, N=50, Completed, Sponsor: National Taiwan University Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Completed

|||||||||| Enrollment change: Improving Hand and Arm Function After Spinal Cord Injury (SCI) (clinicaltrials.gov) - Oct 8, 2013
P=N/A, N=48, Completed, Sponsor: University of Miami
Not yet recruiting --> Completed N=72 --> 48

|||||||||| Enrollment open: Skilled Motor Training and tDCS to Improve Leg Function After Spinal Cord Injury (clinicaltrials.gov) - Oct 8, 2013
P=N/A, N=28, Recruiting, Sponsor: University of Miami
N=72 --> 48 Not yet recruiting --> Recruiting

|||||||||| Trial completion: Improving Hand and Arm Function After Spinal Cord Injury (SCI) (clinicaltrials.gov) - Oct 8, 2013
P=N/A, N=48, Completed, Sponsor: University of Miami
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| Enrollment change: Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation (clinicaltrials.gov) - Sep 25, 2013
P2, N=67, Completed, Sponsor: NovaBay Pharmaceuticals, Inc.
Recruiting --> Completed N=90 --> 67

|||||||||| Trial completion: Study to Evaluate NVC-422 for Urinary Catheter Blockage and Encrustation (clinicaltrials.gov) - Sep 25, 2013
P2, N=67, Completed, Sponsor: NovaBay Pharmaceuticals, Inc.
N=90 --> 67 Recruiting --> Completed

|||||||||| Trial termination: Oxandrolone to Heal Pressure Ulcers (clinicaltrials.gov) - Sep 22, 2013
P3, N=212, Terminated, Sponsor: Department of Veterans Affairs
Recruiting --> Completed Completed --> Terminated; futility analysis showed low probability of detecting a significant difference

|||||||||| Trial withdrawal: BIONs, for Improved Tissue Health and Pressure Sore Prevention (clinicaltrials.gov) - Sep 15, 2013
P=N/A, N=0, Withdrawn, Sponsor: Department of Veterans Affairs
Completed --> Terminated; futility analysis showed low probability of detecting a significant difference Terminated --> Withdrawn

|||||||||| Trial completion: Low Friction Bed Sheet (clinicaltrials.gov) - Sep 12, 2013
P=N/A, N=20, Completed, Sponsor: Swiss Paraplegic Centre Nottwil
Terminated --> Withdrawn Not yet recruiting --> Completed

||||||||||  alendronate / Generic mfg.
Trial termination:  Pilot Study of Fosamax in Spinal Cord Injury (clinicaltrials.gov) -  Sep 11, 2013
P=N/A, N=1, Terminated,  Sponsor: University of Rochester
Not yet recruiting --> Completed Recruiting --> Terminated; Only 1 participant enrolled since the beginning of this study

||||||||||  alendronate / Generic mfg.
Enrollment change:  Pilot Study of Fosamax in Spinal Cord Injury (clinicaltrials.gov) -  Sep 11, 2013
P=N/A, N=1, Terminated,  Sponsor: University of Rochester
Recruiting --> Terminated; Only 1 participant enrolled since the beginning of this study N=10 --> 1

|||||||||| Enrollment closed: Effect of Teriparatide, Vibration and the Combination on Bone Mass and Bone Architecture in Chronic Spinal Cord Injury (clinicaltrials.gov) - Sep 4, 2013
P2, N=60, Active, not recruiting, Sponsor: Thomas J. Schnitzer
N=10 --> 1 Recruiting --> Active, not recruiting

|||||||||| Clinical: Clinical Evaluation of Instrumented Wheel as Biomedical Device Quantifying the Displacement Efficiency (clinicaltrials.gov) - Sep 3, 2013
P=N/A, N=62, Recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris

|||||||||| Enrollment open: DRTMS: Deep rTMS in Central Neuropathic Pain Syndromes (clinicaltrials.gov) - Aug 28, 2013
P=N/A, N=90, Recruiting, Sponsor: University of Sao Paulo
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting

||||||||||  midodrine hydrochloride / Generic mfg.
Trial completion:  Safety and Efficacy of L-NAME and Midodrine to Increase MAP (clinicaltrials.gov) -  Aug 28, 2013
P2, N=34, Completed,  Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| Trial completion: Telephone Intervention for Pain Study (TIPS) (clinicaltrials.gov) - Aug 28, 2013
P=N/A, N=207, Completed, Sponsor: University of Washington
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Enrollment closed: A Colonic Tube to Improve Bowel Function in Spinal Cord Injury (clinicaltrials.gov) - Aug 26, 2013
P=N/A, N=25, Active, not recruiting, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Recruiting --> Active, not recruiting

|||||||||| Trial completion, Metastases: CRUK-SCORAD: Radiation Therapy in Treating Patients With Metastatic Spinal Cord Compression (clinicaltrials.gov) - Aug 22, 2013
P=N/A, N=100, Completed, Sponsor: Cancer Research UK
Recruiting --> Active, not recruiting Recruiting --> Completed

|||||||||| Enrollment change, Metastases: Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction (clinicaltrials.gov) - Aug 21, 2013
P=N/A, N=96, Recruiting, Sponsor: University of Zurich
Recruiting --> Completed N=77 --> 96

|||||||||| Trial completion: Spinal Cord Injury: Endurance, Strength and Cardiac Function Induced by Efficient Training Protocols (clinicaltrials.gov) - Aug 18, 2013
P0, N=12, Completed, Sponsor: Norwegian University of Science and Technology
N=77 --> 96 Active, not recruiting --> Completed

|||||||||| Clinical: Evaluation of a Bowel and Bladder Health Management Program for Individuals With Spinal Cord Injury (SCI) (clinicaltrials.gov) - Aug 7, 2013
P=N/A, N=50, Enrolling by invitation, Sponsor: University of Michigan

||||||||||  pregabalin / Generic mfg.
Trial termination:  Study of Pregabalin in the Prevention of Central Neuropathic Pain in Acute Spinal Cord Injury (clinicaltrials.gov) -  Jul 28, 2013
P3, N=5, Terminated,  Sponsor: Capital District Health Authority, Canada
Active, not recruiting --> Completed Enrolling by invitation --> Terminated; lack of funding and patients

||||||||||  pregabalin / Generic mfg.
Enrollment change:  Study of Pregabalin in the Prevention of Central Neuropathic Pain in Acute Spinal Cord Injury (clinicaltrials.gov) -  Jul 28, 2013
P3, N=5, Terminated,  Sponsor: Capital District Health Authority, Canada
Enrolling by invitation --> Terminated; lack of funding and patients N=30 --> 5

|||||||||| New P2 trial: Botulinum Toxin Type A for Treating Allodynic Pain in SCI and MS (clinicaltrials.gov) - Jul 28, 2013
P2, N=12, Recruiting, Sponsor: University of Manitoba

||||||||||  droxidopa / Generic mfg.
Trial completion:  A Dose Titration of Droxidopa in Patients With Spinal Cord Injury (clinicaltrials.gov) -  Jul 28, 2013
P1, N=11, Completed,  Sponsor: Bronx VA Medical Center
N=30 --> 5 Recruiting --> Completed

|||||||||| New P1 trial, Stroma: CME-LEM1: Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia (clinicaltrials.gov) - Jul 24, 2013
P1, N=12, Recruiting, Sponsor: Puerta de Hierro University Hospital

||||||||||  carbidopa/levodopa / Generic mfg.
Enrollment open:  Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury (clinicaltrials.gov) -  Jul 18, 2013
P1/2, N=51, Recruiting,  Sponsor: Nordic Life Science Pipeline Inc.
Recruiting --> Completed Not yet recruiting --> Recruiting

|||||||||| Enrollment open: AC105 in Patients With Acute Traumatic Spinal Cord Injury (clinicaltrials.gov) - Jul 16, 2013
P2, N=40, Enrolling by invitation, Sponsor: Acorda Therapeutics
Not yet recruiting --> Recruiting Not yet recruiting --> Enrolling by invitation

|||||||||| Enrollment change: The Effects of Transcranial Direct Current Stimulation on Central Pain in Patients With Spinal Cord Injury (clinicaltrials.gov) - Jul 11, 2013
P2, N=16, Completed, Sponsor: Seoul National University Bundang Hospital
Not yet recruiting --> Enrolling by invitation N=11 --> 16

|||||||||| New P4 trial: Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels (clinicaltrials.gov) - Jul 9, 2013
P4, N=30, Recruiting, Sponsor: University of Manitoba

|||||||||| Enrollment open: Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels (clinicaltrials.gov) - Jul 9, 2013
P4, N=30, Recruiting, Sponsor: University of Manitoba
N=11 --> 16 Not yet recruiting --> Recruiting

||||||||||  riluzole / Generic mfg.
Trial completion:  Safety of Riluzole in Patients With Acute Spinal Cord Injury (clinicaltrials.gov) -  Jun 10, 2013
P=N/A, N=36, Completed,  Sponsor: The Methodist Hospital System
Not yet recruiting --> Recruiting Active, not recruiting --> Completed

|||||||||| Enrollment change: Functional and Physiological Responses to Lokomat Therapy (Pilot Study) (clinicaltrials.gov) - Jun 9, 2013
P=N/A, N=27, Completed, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed N=80 --> 27

|||||||||| New P2 trial: Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury (clinicaltrials.gov) - Jun 9, 2013
P2, N=10, Recruiting, Sponsor: University of British Columbia

|||||||||| New P3 trial: Different Efficacy Between Rehabilitation Therapy and Stem Cells Transplantation in Patients With SCI in China (clinicaltrials.gov) - Jun 6, 2013
P3, N=300, Recruiting, Sponsor: General Hospital of Chinese Armed Police Forces

|||||||||| Trial completion: Functional and Physiological Responses to Lokomat Therapy (Pilot Study) (clinicaltrials.gov) - May 30, 2013
P=N/A, N=27, Completed, Sponsor: Department of Veterans Affairs
N=80 --> 27 Active, not recruiting --> Completed

|||||||||| Enrollment change: Pilot Study: The Role of Macrophage Migration Inhibitory Factor (MIF) in Spinal Cord Injury (clinicaltrials.gov) - May 22, 2013
P=N/A, N=287, Recruiting, Sponsor: North Shore Long Island Jewish Health System
Active, not recruiting --> Completed N=75 --> 287

|||||||||| New P2 trial: Prognostic Value of Biochemical Markers in Cerebrospinal Fluid for Functional Outcome of Spinal Cord Injured Patients (clinicaltrials.gov) - May 22, 2013
P2, N=30, Recruiting, Sponsor: Azienda Usl di Bologna

|||||||||| Enrollment open: Cardiovascular Disease Study (clinicaltrials.gov) - May 22, 2013
P=N/A, N=200, Recruiting, Sponsor: Department of Veterans Affairs
N=75 --> 287 Active, not recruiting --> Recruiting

|||||||||| Trial completion: APSCI: Acupuncture Treatment to Reduce Burning Pain in Spinal Cord Injury (clinicaltrials.gov) - May 19, 2013
P=N/A, N=33, Completed, Sponsor: Toronto Rehabilitation Institute
Active, not recruiting --> Recruiting Recruiting --> Completed

|||||||||| Enrollment change: Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage (clinicaltrials.gov) - May 16, 2013
P4, N=110, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed N=52 --> 110

||||||||||  lithium carbonate ER / Generic mfg.
New P2 trial:  Study to Evaluate the Efficacy of Lithium Carbonate in Spinal Cord Injury Patients With Neuropathic Pain (clinicaltrials.gov) -  May 14, 2013
P2, N=60, Recruiting,  Sponsor: China Spinal Cord Injury Network

|||||||||| Trial completion: Efficacy and Safety of Standard Oral Colonoscopic Preparations With or Without Neostigmine Compared to Pulse-Irrigation Colonic Lavage (clinicaltrials.gov) - May 14, 2013
P4, N=110, Completed, Sponsor: Department of Veterans Affairs
N=52 --> 110 Recruiting --> Completed

|||||||||| Trial completion: BALNEORESPI: Effect of Immersion Level on Respiratory Function of Spinal Cord Injury Patients During Balneotherapy (clinicaltrials.gov) - May 2, 2013
P=N/A, N=15, Completed, Sponsor: Centre d'Investigation Clinique et Technologique 805
Recruiting --> Completed Recruiting --> Completed

|||||||||| Enrollment change: Effect of Vibration Therapy on Bone in Persons With Sub-acute Spinal Cord Injury (clinicaltrials.gov) - Apr 24, 2013
P=N/A, N=1, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Completed N=20 --> 1

|||||||||| Trial completion: Effect of Vibration Therapy on Bone in Persons With Sub-acute Spinal Cord Injury (clinicaltrials.gov) - Apr 24, 2013
P=N/A, N=1, Completed, Sponsor: Department of Veterans Affairs
N=20 --> 1 Recruiting --> Completed

|||||||||| Trial completion: Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients (clinicaltrials.gov) - Apr 22, 2013
P4, N=40, Completed, Sponsor: Catholic University of Korea Saint Paul's Hospital
Recruiting --> Completed Not yet recruiting --> Completed

|||||||||| Trial completion: Functional Electrical Stimulation (FES) Driven Stepping in Individuals With Spinal Cord Injury (clinicaltrials.gov) - Apr 16, 2013
P1/2, N=12, Completed, Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Not yet recruiting --> Completed Active, not recruiting --> Completed