Soft Tissue Sarcoma MOAs

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Phase N/A 1 2 3 4 Products	0	5	10	15	20	25	30	35	40	45	50



VEGF-A inhib




IFNα stim




Alkylating agent




VEGF-A inhib




mTORC2 inhib




DNA inhib




HDAC2 inhib




PDGFR β inhib




CD20 inhib




c-KIT inhib




Microtubule inhib




FGFR1 inhib




IL-11 stim




TIE-2 inhib




EGFR inhib




Estrogen receptor mod




IFNα stim




mTOR inhib




IGF-1R inhib




AKT inhib




Apoptosis stim




PARP3 inhib




PIGF inhib




TNFα inhib




GM-CSF agon




Hedgehog cell-signalling pathway inhib




IL-6 inhib




Opioid receptor agon




PI3K inhib




Vascular disrupting agent




Bcl2 inhib




Bcl2 inhib




CCR5 receptor antag




Estrogen receptor mod




IL-1β inhib




SMO protein inhib




TRAIL R2 inhib




Aurora kinase A inhib




BRAF inhib




CD20 inhib




CDK6 inhib




CTLA4 inhib




Calcineurin inhib




DHODH inhib




DNA PK inhib




Factor X inhib




Gonadotropin inhib




HER2 inhib




HIF-1 inhib




HSP90 inhib



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