Small Non-cleaved Cell Lymphoma News

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|||||||||| Trial completion, IO biomarker: Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer (clinicaltrials.gov) - Feb 26, 2014
P2, N=53, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed

||||||||||  Neupogen (filgrastim) / Kyowa Kirin, Amgen, NN1213 / Novo Nordisk
Trial completion:  Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease (clinicaltrials.gov) -  Feb 22, 2014
P1/2, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  sorafenib / Generic mfg.
Trial completion, Metastases:  Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function (clinicaltrials.gov) -  Feb 22, 2014
P1, N=150, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Campath (alemtuzumab) / Sanofi
Trial completion, Combination therapy:  Campath-1H + FK506 and Methylprednisolone for GVHD (clinicaltrials.gov) -  Feb 22, 2014
P2, N=34, Completed,  Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  decitabine / Generic mfg.
Trial completion, Combination therapy:  Decitabine With or Without Valproic Acid in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P1, N=42, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  oxaliplatin / Generic mfg., irinotecan / Generic mfg.
Trial completion:  Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas (clinicaltrials.gov) -  Feb 22, 2014
P1, N=24, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  Jingzhuda (entinostat) / EOC Pharma, EddingPharm
Trial completion, Combination therapy, Epigenetic controller, Metastases:  MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas (clinicaltrials.gov) -  Feb 22, 2014
P1, N=24, Completed,  Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  mycophenolate mofetil / Generic mfg.
Trial completion, Metastases:  Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) -  Feb 22, 2014
P2, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion, Metastases: 17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas (clinicaltrials.gov) - Feb 22, 2014
P1, N=60, Completed, Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  sirolimus / Generic mfg.
Trial completion:  Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) -  Feb 22, 2014
P1/2, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion, Metastases:  17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in Treating Patients With an Advanced Solid Tumor or Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P1, N=40, Completed,  Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Study of the Emotional Needs of Caregivers of Stem Cell Transplantation Patients (clinicaltrials.gov) -  Feb 22, 2014
P=N/A, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Istodax (romidepsin) / Astellas, BMS
Trial completion, Epigenetic controller:  FR901228 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P2, N=35, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  Cilcane (cilengitide) / Iceni Pharma
Trial completion, Metastases:  Cilengitide (EMD 121974) in Treating Patients With Advanced Solid Tumors or Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P1, N=45, Completed,  Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Fodosine (forodesine) / Mundipharma, BioCryst
Trial completion:  BCX-1777 in Treating Patients With Refractory Cancer (clinicaltrials.gov) -  Feb 22, 2014
P1, N=0, Completed,  Sponsor: BioCryst Pharmaceuticals
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  voriconazole / Generic mfg.
Trial completion:  Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapy (clinicaltrials.gov) -  Feb 22, 2014
P2, N=0, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  megestrol / Generic mfg.
Trial completion:  Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment (clinicaltrials.gov) -  Feb 22, 2014
P2, N=70, Completed,  Sponsor: University of South Florida
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Rituxan (rituximab) / Roche
Trial completion:  Epirubicin and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia (clinicaltrials.gov) -  Feb 22, 2014
P2, N=5, Completed,  Sponsor: Fox Chase Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  cyclophosphamide / Generic mfg.
Trial completion:  Total-Body Irradiation, Cyclophosphamide, and Stem Cell Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) -  Feb 22, 2014
P1, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  Zevalin (ibritumomab tiuxetan) / Servier, Aurobindo
Trial completion:  Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P1, N=44, Completed,  Sponsor: Northwestern University
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Neupogen (filgrastim) / Kyowa Kirin, Amgen, NN1213 / Novo Nordisk
Trial completion:  Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders (clinicaltrials.gov) -  Feb 22, 2014
P2, N=0, Completed,  Sponsor: Roswell Park Cancer Institute
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Onrigin (laromustine) / Vion
Trial completion, Metastases:  VNP40101M in Treating Patients With Advanced or Metastatic Cancer (clinicaltrials.gov) -  Feb 22, 2014
P1, N=0, Completed,  Sponsor: Vion Pharmaceuticals
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Standard Follow-up Compared With Extended Follow-up in Treating Patients Who Have Undergone Stem Cell Transplantation for Cancer (clinicaltrials.gov) -  Feb 22, 2014
P=N/A, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Neupogen (filgrastim) / Kyowa Kirin, Amgen, NN1213 / Novo Nordisk, Matulane (procarbazine hydrochloride) / Leadiant Biosci
Trial completion:  Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P2, N=54, Completed,  Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  thalidomide / Generic mfg., docetaxel / Generic mfg.
Trial completion, Metastases:  Thalidomide and Docetaxel in Treating Patients With Advanced Cancer (clinicaltrials.gov) -  Feb 22, 2014
P1, N=26, Completed,  Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  mitoxantrone / Generic mfg., cytarabine / Generic mfg.
Trial completion:  Combination Chemotherapy in Treating Patients With Recurrent or Refractory Leukemia or Lymphoma (clinicaltrials.gov) -  Feb 22, 2014
P2, N=3, Completed,  Sponsor: Case Comprehensive Cancer Center
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  valacyclovir / Generic mfg.
Trial completion:  Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation (clinicaltrials.gov) -  Feb 22, 2014
P3, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  lenalidomide / Generic mfg., thalidomide / Generic mfg.
Trial completion, Metastases:  CC-5013 in Treating Patients With Cancer That Has Not Responded to Previous Therapy (clinicaltrials.gov) -  Feb 22, 2014
P1, N=0, Completed,  Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Zevalin (ibritumomab tiuxetan) / Servier, Aurobindo
Trial completion, Post-transplantation:  NCI-V02-1691: Monoclonal Antibody Therapy in Relapsed Non-Hodgkin's After Chemotherapy and Autologous Stem Cell Transplantation (clinicaltrials.gov) -  Feb 22, 2014
P1/2, N=26, Completed,  Sponsor: University of Nebraska
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma (clinicaltrials.gov) - Feb 22, 2014
P2, N=0, Completed, Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Campath (alemtuzumab) / Sanofi
Trial completion:  Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer (clinicaltrials.gov) -  Feb 22, 2014
P2, N=51, Completed,  Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  imatinib / Generic mfg.
Trial completion, Metastases:  Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction (clinicaltrials.gov) -  Feb 22, 2014
P1, N=60, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  busulfan / Generic mfg.
Trial initiation date:  Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant (clinicaltrials.gov) -  Feb 20, 2014
P0, N=30, Recruiting,  Sponsor: Case Comprehensive Cancer Center
No longer recruiting --> Completed Initiation date: Nov 2013 --> Mar 2014

||||||||||  Zolinza (vorinostat) / Merck (MSD)
Enrollment change, Metastases:  Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction (clinicaltrials.gov) -  Feb 20, 2014
P1, N=15, Completed,  Sponsor: National Cancer Institute (NCI)
Initiation date: Nov 2013 --> Mar 2014 N=118 --> 15

||||||||||  Zolinza (vorinostat) / Merck (MSD)
Enrollment change, Combination therapy, Metastases:  Vorinostat and Decitabine in Treating Patients With Advanced Solid Tumors or Relapsed or Refractory Non-Hodgkin's Lymphoma, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Chronic Myelogenous Leukemia (clinicaltrials.gov) -  Feb 20, 2014
P1, N=80, Active, not recruiting,  Sponsor: National Cancer Institute (NCI)
N=118 --> 15 N=61 --> 80

||||||||||  vincristine / Generic mfg.
Trial completion:  Bryostatin 1 Plus Vincristine in Treating Patients With Recurrent or Refractory HIV-Related Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P1, N=12, Completed,  Sponsor: National Cancer Institute (NCI)
N=61 --> 80 No longer recruiting --> Completed

||||||||||  Emcyt (estramustine) / Pfizer, Nippon Shinyaku
Trial completion:  Paclitaxel and Estramustine in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P2, N=25, Completed,  Sponsor: Fox Chase Cancer Center
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Jingzhuda (entinostat) / EOC Pharma, EddingPharm
Trial completion, Epigenetic controller, Metastases:  MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P1, N=75, Completed,  Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  paclitaxel / Generic mfg.
Trial completion, Metastases:  Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas (clinicaltrials.gov) -  Feb 19, 2014
P1, N=70, Completed,  Sponsor: National Institutes of Health Clinical Center (CC)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  Avastin (bevacizumab) / Roche
Trial completion:  S0108 Bevacizumab in Treating Patients With Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P2, N=60, Completed,  Sponsor: National Cancer Institute (NCI)
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Music Therapy to Ease Pain and Emotional Distress in Patients With Hematologic Cancer Who Are Undergoing High-Dose Therapy and Stem Cell Transplantation (clinicaltrials.gov) -  Feb 19, 2014
P=N/A, N=0, Completed,  Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Synagis (palivizumab) / AbbVie, AstraZeneca, SOBI
Trial completion:  Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation (clinicaltrials.gov) -  Feb 19, 2014
P3, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon (clinicaltrials.gov) -  Feb 19, 2014
P1/2, N=0, Completed,  Sponsor: Fred Hutchinson Cancer Research Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  amphotericin b liposome / Generic mfg.
Trial completion:  Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment (clinicaltrials.gov) -  Feb 19, 2014
P3, N=0, Completed,  Sponsor: Memorial Sloan-Kettering Cancer Center
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  oxaliplatin / Generic mfg.
Trial completion:  Oxaliplatin in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P2, N=72, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  bortezomib / Generic mfg.
Trial completion, Metastases:  PS-341 in Treating Patients With Advanced Cancer (clinicaltrials.gov) -  Feb 19, 2014
P1, N=0, Completed,  Sponsor: Mayo Clinic
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  Neupogen (filgrastim) / Kyowa Kirin, Amgen, NN1213 / Novo Nordisk
Trial completion:  Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer (clinicaltrials.gov) -  Feb 19, 2014
P1/2, N=0, Completed,  Sponsor: Northwestern University
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  NN1213 / Novo Nordisk
Trial completion:  Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma (clinicaltrials.gov) -  Feb 19, 2014
P2, N=200, Completed,  Sponsor: National Cancer Institute (NCI)
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  cyclophosphamide / Generic mfg.
Trial completion, Pre-transplantation:  Cyclophosphamide Plus Bone Marrow Transplantation in Treating Patients With Hematologic Cancer (clinicaltrials.gov) -  Feb 19, 2014
P1, N=0, Completed,  Sponsor: Sidney Kimmel Comprehensive Cancer Center
No longer recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion, Metastases: Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia (clinicaltrials.gov) - Feb 19, 2014
P3, N=83, Completed, Sponsor: Children's Oncology Group
Active, not recruiting --> Completed No longer recruiting --> Completed



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