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26 Companies |
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24 Products |
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24 Products |
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22 Mechanisms of Action |
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2 Trials |
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625 News |
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- ||||| Enrollment closed: Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2 (clinicaltrials.gov) - Nov 17, 2014
P3, N=250, Active, not recruiting, Sponsor: Healthpoint
Recruiting --> Active, not recruiting
- ||||| Invanz (ertapenem) / Merck (MSD)
Trial initiation date: Comparative Study of Ertapenem Versus Another Antibiotic in the Treatment of Diabetic Foot Infections in Adults (0826-034) (clinicaltrials.gov) - Nov 13, 2014
P3, N=400, Completed, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Active, not recruiting Initiation date: Mar 2002 --> Apr 2001
- Trial completion, Phase classification, Trial primary completion date: Intraarterial Infusion of Autologous Bone Marrow in Diabetic Patients With Chronic Ischemia of Lower Limbs (CLI) no Revascularization (clinicaltrials.gov) - Nov 13, 2014
P2, N=60, Completed, Sponsor: Iniciativa Andaluza en Terapias Avanzadas - Fundaci
Initiation date: Mar 2002 --> Apr 2001 Active, not recruiting --> Completed | Phase classification: P1/2 --> P2 | Trial primary completion date: Dec 2011 --> Mar 2013
- Locilex (pexiganan acetate) / PLx Pharma Inc
Trial primary completion date, Head-to-Head: OneStep-2: Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers (clinicaltrials.gov) - Nov 6, 2014
P3, N=180, Recruiting, Sponsor: Dipexium Pharmaceuticals, Inc.
Active, not recruiting --> Completed | Phase classification: P1/2 --> P2 | Trial primary completion date: Dec 2011 --> Mar 2013 Trial primary completion date: Oct 2014 --> Mar 2015
- Locilex (pexiganan acetate) / PLx Pharma Inc
Trial primary completion date, Head-to-Head: OneStep-1: Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers (clinicaltrials.gov) - Nov 6, 2014
P3, N=180, Recruiting, Sponsor: Dipexium Pharmaceuticals, Inc.
Trial primary completion date: Oct 2014 --> Mar 2015 Trial primary completion date: Oct 2014 --> Mar 2015
- Trial primary completion date: Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (clinicaltrials.gov) - Nov 5, 2014
P=N/A, N=76, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
Trial primary completion date: Oct 2014 --> Mar 2015 Trial primary completion date: May 2015 --> May 2016
- Trial primary completion date: A Pilot Study of the Provant Therapy System in Subjects With Diabetic Foot Ulcers (clinicaltrials.gov) - Nov 5, 2014
P=N/A, N=30, Terminated, Sponsor: Regenesis Biomedical, Inc.
Trial primary completion date: May 2015 --> May 2016 Trial primary completion date: Jan 2013 --> Mar 2011
- | doxycycline / Generic mfg.
New P2 trial: Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana (clinicaltrials.gov) - Nov 3, 2014
P2, N=200, Not yet recruiting, Sponsor: Kwame Nkrumah University of Science and Technology
- Real-world evidence, Real-world: A Real World, Observational Registry of Chronic Wounds and Ulcers (clinicaltrials.gov) - Oct 31, 2014
P=N/A, N=175000, Recruiting, Sponsor: U.S. Wound Registry
- Trial suspension, Trial primary completion date: Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers (clinicaltrials.gov) - Oct 30, 2014
P2, N=30, Suspended, Sponsor: Phoenix Eagle Company
Trial primary completion date: Jan 2013 --> Mar 2011 Active, not recruiting --> Suspended | Trial primary completion date: Dec 2012 --> Dec 2016
- Clinical: A Randomized, Prospective Clinical Trial of Immediate Flap Closure Versus Wound Care for Management of Late-stage Pressure Ulcers (clinicaltrials.gov) - Oct 23, 2014
P=N/A, N=50, Not yet recruiting, Sponsor: Santa Barbara Cottage Hospital
- ||| Trial completion, Enrollment change: Evaluation of an E-learning Program for Assessing Pressure Ulcer Risk and Pressure Ulcer Classification - a Pilot Study (clinicaltrials.gov) - Oct 23, 2014
P=N/A, N=68, Completed, Sponsor: Oslo University Hospital
Active, not recruiting --> Suspended | Trial primary completion date: Dec 2012 --> Dec 2016 Recruiting --> Completed | N=90 --> 68
- Clinical: The Effectiveness of a Pressure Ulcer Prevention Programme for Older People in For-profit Private Nursing Homes (clinicaltrials.gov) - Oct 22, 2014
P=N/A, N=1126, Not yet recruiting, Sponsor: The Hong Kong Polytechnic University
- | Januvia (sitagliptin) / Merck (MSD)
Phase classification: Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers (clinicaltrials.gov) - Oct 20, 2014
P4, N=250, Recruiting, Sponsor: Georgetown University
Recruiting --> Completed | N=90 --> 68 Phase classification: P2 --> P4
- Trial primary completion date: Testing Fish Oil Derivatives In Healing Of Chronic Venous Leg Ulcers (clinicaltrials.gov) - Oct 17, 2014
P=N/A, N=108, Recruiting, Sponsor: Ohio State University
Phase classification: P2 --> P4 Trial primary completion date: Jun 2014 --> Jun 2015
- Enrollment closed, Trial primary completion date: Proof-of-concept Study for Bioimpedance Based Monitoring of Venous Ulcers During Galvanic Stimulation (clinicaltrials.gov) - Oct 17, 2014
P=N/A, N=10, Active, not recruiting, Sponsor: Tampere University Hospital
Trial primary completion date: Jun 2014 --> Jun 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2014 --> Dec 2014
- Enrollment change: Self-Management to Prevent Ulcers in Veterans With SCI (Spinal Cord Injury) (clinicaltrials.gov) - Oct 15, 2014
P=N/A, N=144, Completed, Sponsor: Department of Veterans Affairs
Recruiting --> Active, not recruiting | Trial primary completion date: Jul 2014 --> Dec 2014 N=400 --> 144
- || Trial primary completion date: Efficacy Study of IZN-6D4 Gel for the Treatment of Diabetic Foot Ulcers (clinicaltrials.gov) - Oct 11, 2014
P2, N=80, Recruiting, Sponsor: Izun Pharma Ltd
N=400 --> 144 Trial primary completion date: Mar 2014 --> Jun 2015
- LeukoScan (sulesomab) / Gilead
Enrollment change, Trial termination, Trial primary completion date: ISEOD: PET/CT Scanning for the Follow-up of Antibiotic Treatment of Infectious Osteoarthritis in the Diabetic Foot (clinicaltrials.gov) - Oct 11, 2014
P=N/A, N=12, Terminated, Sponsor: Centre Hospitalier Universitaire de Nīmes
Trial primary completion date: Mar 2014 --> Jun 2015 N=109 --> 12 | Recruiting --> Terminated | Trial primary completion date: Oct 2015 --> Nov 2014; The study has proven to be infeasible.
- | Grafix (cryopreserved placental membrane) / Osiris
New P4 trial: GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds (clinicaltrials.gov) - Oct 10, 2014
P4, N=40, Recruiting, Sponsor: Osiris Therapeutics
- | Trial completion: Split Thickness Donor Site Healing With MIST Study (clinicaltrials.gov) - Oct 10, 2014
P=N/A, N=34, Completed, Sponsor: Celleration, Inc.
N=109 --> 12 | Recruiting --> Terminated | Trial primary completion date: Oct 2015 --> Nov 2014; The study has proven to be infeasible. Enrolling by invitation --> Completed
- Enrollment open: EZCast-DFU Study With Portal for Application of Topical Medications (clinicaltrials.gov) - Oct 10, 2014
P4, N=3, Recruiting, Sponsor: University of Miami
Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
- Enrollment open: Transcutaneous Raman Spectroscope (TRS) Analyses of Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 30, 2014
P=N/A, N=30, Recruiting, Sponsor: University of Michigan
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- |||| Trial completion: Study of Oasis Ultra in Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 29, 2014
P4, N=82, Completed, Sponsor: Healthpoint
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||||| New P4 trial: A Prospective, Randomized, Controlled, Multi-Center, Study Evaluating AutoloGel Therapy for Complete Closure of Wagner Grade 1-4 Diabetic Foot Ulcers, Venous Leg Ulcers and Stage II-IV Pressure Ulcers (clinicaltrials.gov) - Sep 28, 2014
P4, N=4140, Not yet recruiting, Sponsor: Cytomedix
- | Clinical protocol, Trial completion, Enrollment change: Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 28, 2014
P2, N=15, Completed, Sponsor: PluroGen Therapeutics, Inc
Active, not recruiting --> Completed Recruiting --> Completed | N=25 --> 15
- | Clinical protocol, Trial completion: Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 28, 2014
P2, N=42, Completed, Sponsor: PluroGen Therapeutics, Inc
Recruiting --> Completed | N=25 --> 15 Recruiting --> Completed
- Enrollment open: Post Market Clinical Follow-up Investigation to Evaluate Performance and Safety on Pressure Ulcers, PU, When Using Exufiber as Intended (clinicaltrials.gov) - Sep 22, 2014
P=N/A, N=20, Recruiting, Sponsor: Molnlycke Health Care AB
Recruiting --> Completed Not yet recruiting --> Recruiting
- | Trial completion: Prevention of Secondary Foot Ulcers in Patients With Diabetes Using Systematic Measuring of Skin Temperature. (clinicaltrials.gov) - Sep 22, 2014
P=N/A, N=41, Completed, Sponsor: Oslo University Hospital
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- || nitric oxide (EDX110) / Edixomed
Trial primary completion date: ProNOx1: Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 12, 2014
P1/2, N=140, Recruiting, Sponsor: Edixomed Ltd
Active, not recruiting --> Completed Trial primary completion date: Aug 2014 --> May 2015
- |||||||||| New P3 trial: A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer (clinicaltrials.gov) - Sep 11, 2014
P3, N=252, Not yet recruiting, Sponsor: Adocia
- Clinical: Combination of Taliderm® and Vacuum-assisted Closure (VAC) for Treatment of Pressure Ulcers (clinicaltrials.gov) - Sep 11, 2014
P0, N=24, Terminated, Sponsor: University Hospital, Basel, Switzerland
- || Enrollment closed, Trial primary completion date: Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 10, 2014
P=N/A, N=84, Active, not recruiting, Sponsor: MiMedx Group, Inc.
Trial primary completion date: Aug 2014 --> May 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Jul 2015
- Trial primary completion date: Comparison of Resin Salve and Octenidine in Patients With Neuropathic Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 9, 2014
P=N/A, N=40, Recruiting, Sponsor: Janne J. Jokinen
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Jul 2015 Trial primary completion date: Jul 2014 --> Nov 2014
- | Enrollment open: A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs (clinicaltrials.gov) - Aug 27, 2014
P4, N=20, Recruiting, Sponsor: Smith & Nephew Medical Ltd
Trial primary completion date: Jul 2014 --> Nov 2014 Not yet recruiting --> Recruiting
- ||| Trial completion: A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 26, 2014
P=N/A, N=307, Completed, Sponsor: Integra LifeSciences Corporation
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Clinical: Post Market Clinical Follow-up Investigation to Evaluate Performance and Safety on Pressure Ulcers, PU, When Using Exufiber as Intended (clinicaltrials.gov) - Aug 25, 2014
P=N/A, N=20, Not yet recruiting, Sponsor: Molnlycke Health Care AB
- | New P4 trial: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 25, 2014
P4, N=250, Recruiting, Sponsor: Nottingham University Hospitals NHS Trust
- Enrollment open, Trial primary completion date: Askina Calgitrol Paste Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 22, 2014
P=N/A, N=35, Recruiting, Sponsor: BBraun Medical SAS
Active, not recruiting --> Completed Not yet recruiting --> Recruiting | Trial primary completion date: Nov 2013 --> Dec 2014
- pirfenidone / Generic mfg.
New P3 trial: PirDFI: Effect of Topic Pirfenidone in Diabetic Ulcers (clinicaltrials.gov) - Aug 21, 2014
P3, N=50, Recruiting, Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Trial initiation date, Trial primary completion date: EZCast-DFU Study With Portal for Application of Topical Medications (clinicaltrials.gov) - Aug 21, 2014
P4, N=3, Not yet recruiting, Sponsor: University of Miami
Not yet recruiting --> Recruiting | Trial primary completion date: Nov 2013 --> Dec 2014 Initiation date: May 2014 --> Sep 2014 | Trial primary completion date: May 2015 --> Sep 2015
- Clinical: Safety Evaluation of the KLOX BioPhotonic System in Venous Leg Ulcers (clinicaltrials.gov) - Aug 21, 2014
P=N/A, N=10, Recruiting, Sponsor: KLOX Technologies Inc.
- Clinical: Safety Evaluation of the KLOX BioPhotonic System in Stage II and III Pressure Ulcers (clinicaltrials.gov) - Aug 21, 2014
P=N/A, N=5, Recruiting, Sponsor: KLOX Technologies Inc.
- Clinical: Safety Evaluation of the KLOX BioPhotonic System in Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 21, 2014
P=N/A, N=10, Recruiting, Sponsor: KLOX Technologies Inc.
- |||| Enrollment open: Efficacy of AutoloGel Therapy to Usual and Customary Care in Wagner gd 1 and 2 Diabetic Foot Ulcers. (clinicaltrials.gov) - Aug 19, 2014
P4, N=280, Recruiting, Sponsor: Cytomedix
Initiation date: May 2014 --> Sep 2014 | Trial primary completion date: May 2015 --> Sep 2015 Not yet recruiting --> Recruiting
- Enrollment change, Trial termination: Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia (clinicaltrials.gov) - Aug 11, 2014
P2, N=6, Terminated, Sponsor: Molnlycke Health Care AB
Not yet recruiting --> Recruiting N=36 --> 6 | Recruiting --> Terminated
- | Trial initiation date, Head-to-Head: Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers. (clinicaltrials.gov) - Aug 8, 2014
P3, N=92, Not yet recruiting, Sponsor: Cristália Produtos Químicos Farmacêuticos Ltda.
N=36 --> 6 | Recruiting --> Terminated Initiation date: Jun 2014 --> Jan 2015
- || Enrollment closed, Enrollment change: Effects of Non Contact Low Frequency Ultrasound in Healing Venous Leg Ulcers (clinicaltrials.gov) - Aug 7, 2014
P=N/A, N=156, Active, not recruiting, Sponsor: Celleration, Inc.
Initiation date: Jun 2014 --> Jan 2015 Recruiting --> Active, not recruiting | N=208 --> 156
- Enrollment open: CHEXU 01: Open, Non-comparative, Multi-centre Post Marketing Clinical Follow-up Investigation to Evaluate Performance and Safety on Diabetic Foot Ulcer, DFU When Using Fast Gelling Dressing as Intended. (clinicaltrials.gov) - Aug 6, 2014
P=N/A, N=25, Recruiting, Sponsor: Molnlycke Health Care AB
Recruiting --> Active, not recruiting | N=208 --> 156 Not yet recruiting --> Recruiting
- | New P4 trial: Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 5, 2014
P4, N=30, Recruiting, Sponsor: Derma Sciences, Inc.