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26 Companies |
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24 Products |
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24 Products |
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22 Mechanisms of Action |
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2 Trials |
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625 News |
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- | Trial primary completion date: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers (clinicaltrials.gov) - Apr 19, 2017
P4, N=250, Recruiting, Sponsor: Nottingham University Hospitals NHS Trust
Trial primary completion date: Feb 2017 --> Nov 2017
- | Trial completion, Enrollment change, Trial primary completion date: Pilot Study on Auricular Vagus Nerve Stimulation Effects in Chronic Diabetic Wounds (clinicaltrials.gov) - Mar 31, 2017
P=N/A, N=24, Completed, Sponsor: Medical University of Vienna
Trial primary completion date: Feb 2017 --> Nov 2017 Active, not recruiting --> Completed | N=20 --> 24 | Trial primary completion date: Dec 2015 --> Apr 2015
- | Trial completion, Enrollment change: Non-Invasive Assessment of Wound Healing With Optical Methods (clinicaltrials.gov) - Mar 30, 2017
P=N/A, N=38, Completed, Sponsor: Drexel University College of Medicine
Active, not recruiting --> Completed | N=20 --> 24 | Trial primary completion date: Dec 2015 --> Apr 2015 Recruiting --> Completed | N=100 --> 38
- || Trial primary completion date: Use of dHACM in the Treatment of Venous Leg Ulcers (clinicaltrials.gov) - Mar 23, 2017
P=N/A, N=120, Active, not recruiting, Sponsor: MiMedx Group, Inc.
Recruiting --> Completed | N=100 --> 38 Trial primary completion date: Feb 2017 --> Jun 2017
- | doxycycline / Generic mfg.
Trial completion, Trial primary completion date: Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana (clinicaltrials.gov) - Mar 23, 2017
P2, N=200, Completed, Sponsor: Kwame Nkrumah University of Science and Technology
Trial primary completion date: Feb 2017 --> Jun 2017 Recruiting --> Completed | Trial primary completion date: Sep 2017 --> Mar 2017
- | Trial completion: Cell Therapy for Venous Leg Ulcers Pilot Study (clinicaltrials.gov) - Mar 6, 2017
P1, N=4, Completed, Sponsor: Hospital de Clínicas Dr. Manuel Quintela
Recruiting --> Completed | Trial primary completion date: Sep 2017 --> Mar 2017 Active, not recruiting --> Completed
- | Trial completion, Enrollment change, Trial primary completion date: Use of Fish Skin Extracellular Matrix (ECM) to Facilitate Chronic Wound Healing (clinicaltrials.gov) - Mar 3, 2017
P=N/A, N=37, Completed, Sponsor: Kerecis Ltd.
Active, not recruiting --> Completed Recruiting --> Completed | N=10 --> 37 | Trial primary completion date: Oct 2011 --> Dec 2012
- | cenplacel (PDA-002) / Celularity
Trial completion: Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU (clinicaltrials.gov) - Feb 24, 2017
P1, N=15, Completed, Sponsor: Celgene
Recruiting --> Completed | N=10 --> 37 | Trial primary completion date: Oct 2011 --> Dec 2012 Active, not recruiting --> Completed
- || Enrollment closed: Use of dHACM in the Treatment of Venous Leg Ulcers (clinicaltrials.gov) - Feb 23, 2017
P=N/A, N=120, Active, not recruiting, Sponsor: MiMedx Group, Inc.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- || Enrollment change, Trial primary completion date: A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen (CDO) Therapy to Standard Moist Wound Therapy (MWT) in the Treatment of Diabetic Foot Ulcers (clinicaltrials.gov) - Feb 12, 2017
P=N/A, N=146, Completed, Sponsor: Electrochemical Oxygen Concepts, Inc.
Recruiting --> Active, not recruiting N=110 --> 146 | Trial primary completion date: Dec 2014 --> Nov 2016
- Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Enrollment change, Trial withdrawal: Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas (clinicaltrials.gov) - Feb 11, 2017
P2, N=0, Withdrawn, Sponsor: Massachusetts Eye and Ear Infirmary
N=110 --> 146 | Trial primary completion date: Dec 2014 --> Nov 2016 N=15 --> 0 | Completed --> Withdrawn
- || Trial primary completion date: Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers (clinicaltrials.gov) - Jan 30, 2017
P=N/A, N=130, Recruiting, Sponsor: MiMedx Group, Inc.
N=15 --> 0 | Completed --> Withdrawn Trial primary completion date: Dec 2016 --> May 2017
- Trial primary completion date: The Pharmacokinetic Study of WH-1 Ointment in Subjects With Chronic Diabetic Foot Ulcers (clinicaltrials.gov) - Jan 26, 2017
P1, N=12, Recruiting, Sponsor: Oneness Biotech Co., Ltd.
Trial primary completion date: Dec 2016 --> May 2017 Trial primary completion date: Mar 2016 --> Jun 2018
- Trial completion, Enrollment change, Trial primary completion date: HADIF: HELP-Apheresis in Diabetic Ischemic Foot Treatment (H.A.D.I.F) (clinicaltrials.gov) - Jan 4, 2017
P=N/A, N=13, Completed, Sponsor: Universita di Verona
Trial primary completion date: Mar 2016 --> Jun 2018 Recruiting --> Completed | N=132 --> 13 | Trial primary completion date: Jan 2017 --> Sep 2015
- Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap
Trial completion, Enrollment change: Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas (clinicaltrials.gov) - Dec 21, 2016
P2, N=15, Completed, Sponsor: Massachusetts Eye and Ear Infirmary
Recruiting --> Completed | N=132 --> 13 | Trial primary completion date: Jan 2017 --> Sep 2015 Recruiting --> Completed | N=60 --> 15
- Trial primary completion date: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers (clinicaltrials.gov) - Nov 22, 2016
P4, N=250, Recruiting, Sponsor: Nottingham University Hospitals NHS Trust
Recruiting --> Completed | N=60 --> 15 Trial primary completion date: Aug 2016 --> Feb 2017
- | Trial completion: PUPS: Pressure Ulcer Prevention Study in SCI (clinicaltrials.gov) - Oct 27, 2016
P3, N=170, Completed, Sponsor: University of Southern California
Trial primary completion date: Aug 2016 --> Feb 2017 Active, not recruiting --> Completed
- Phase classification, Enrollment change, Trial termination: AutoloGel Therapy to Usual and Customary Care in Pressure Ulcers (clinicaltrials.gov) - Oct 21, 2016
P=N/A, N=2, Terminated, Sponsor: Cytomedix
Active, not recruiting --> Completed Phase classification: P4 --> P=N/A | N=400 --> 2 | Active, not recruiting --> Terminated; Protocol study design was re-worked in collaboration with CMS
- Phase classification, Enrollment change, Trial termination, Trial primary completion date: A Cohort Trial Comparing AutoloGel Therapy to Usual and Customary Care in Venous Leg Ulcers (clinicaltrials.gov) - Oct 21, 2016
P=N/A, N=2, Terminated, Sponsor: Cytomedix
Phase classification: P4 --> P=N/A | N=400 --> 2 | Active, not recruiting --> Terminated; Protocol study design was re-worked in collaboration with CMS Phase classification: P4 --> P=N/A | N=385 --> 2 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Jan 2015; Protocol study design was re-done in collaboration with CMS
- Phase classification, Enrollment change, Trial termination, Trial primary completion date: Efficacy of AutoloGel Therapy to Usual and Customary Care in Wagner gd 1 and 2 Diabetic Foot Ulcers. (clinicaltrials.gov) - Oct 21, 2016
P=N/A, N=4, Terminated, Sponsor: Cytomedix
Phase classification: P4 --> P=N/A | N=385 --> 2 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Jan 2015; Protocol study design was re-done in collaboration with CMS Phase classification: P4 --> P=N/A | N=280 --> 4 | Recruiting --> Terminated | Trial primary completion date: Jan 2015 --> Jul 2015; Low enrollment
- Phase classification, Enrollment change, Trial termination, Trial primary completion date: Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers (clinicaltrials.gov) - Oct 21, 2016
P=N/A, N=3, Terminated, Sponsor: Cytomedix
Phase classification: P4 --> P=N/A | N=280 --> 4 | Recruiting --> Terminated | Trial primary completion date: Jan 2015 --> Jul 2015; Low enrollment Phase classification: P4 --> P=N/A | N=380 --> 3 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Jan 2015; Protocol study design was re-done in collaboration with CMS
- Enrollment change, Trial withdrawal: A Prospective, Randomized, Controlled, Multi-Center, Study Evaluating AutoloGel Therapy for Complete Closure of Wagner Grade 1-4 Diabetic Foot Ulcers, Venous Leg Ulcers and Stage II-IV Pressure Ulcers (clinicaltrials.gov) - Oct 21, 2016
P4, N=0, Withdrawn, Sponsor: Cytomedix
Phase classification: P4 --> P=N/A | N=380 --> 3 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Jan 2015; Protocol study design was re-done in collaboration with CMS N=4140 --> 0 | Not yet recruiting --> Withdrawn
- Enrollment open: ADA NPWT: Negative Pressure Wound Therapy as a Drug Delivery System (ADANPWT) (clinicaltrials.gov) - Oct 21, 2016
P=N/A, N=150, Recruiting, Sponsor: University of Texas Southwestern Medical Center
N=4140 --> 0 | Not yet recruiting --> Withdrawn Not yet recruiting --> Recruiting
- Enrollment change, Trial termination, HEOR: Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix (clinicaltrials.gov) - Oct 18, 2016
P=N/A, N=92, Terminated, Sponsor: Integra LifeSciences Corporation
Not yet recruiting --> Recruiting N=224 --> 92 | Active, not recruiting --> Terminated
- Trial completion: Correlation Between Wound Volume and Depth of Decubitus Ulcers And Resting Energy Expenditure (clinicaltrials.gov) - Oct 13, 2016
P=N/A, N=25, Completed, Sponsor: Paul Edwards
N=224 --> 92 | Active, not recruiting --> Terminated Recruiting --> Completed
- ||||| Enrollment closed: ADHOC: The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) (clinicaltrials.gov) - Sep 29, 2016
P3, N=200, Active, not recruiting, Sponsor: INRESA Pharma
Recruiting --> Completed Recruiting --> Active, not recruiting
- Ilaris (canakinumab) / Novartis
Trial completion, Enrollment change, Trial primary completion date: Canakinumab for Pyoderma Gangrenosum (clinicaltrials.gov) - Sep 27, 2016
P2, N=5, Completed, Sponsor: University of Zurich
Recruiting --> Active, not recruiting Recruiting --> Completed | N=10 --> 5 | Trial primary completion date: Aug 2012 --> Aug 2014
- || Trial primary completion date: CMS: Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds (clinicaltrials.gov) - Sep 23, 2016
P=N/A, N=1500, Recruiting, Sponsor: Arteriocyte, Inc.
Recruiting --> Completed | N=10 --> 5 | Trial primary completion date: Aug 2012 --> Aug 2014 Trial primary completion date: Mar 2017 --> Mar 2021
- |||| Trial completion: DermACELL in Subjects With Chronic Wounds of the Lower Extremities (clinicaltrials.gov) - Sep 7, 2016
P4, N=202, Completed, Sponsor: LifeNet Health
Trial primary completion date: Mar 2017 --> Mar 2021 Active, not recruiting --> Completed
- Trial completion: Safety Evaluation of the KLOX BioPhotonic System in Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 6, 2016
P=N/A, N=10, Completed, Sponsor: KLOX Technologies Inc.
Active, not recruiting --> Completed Active, not recruiting --> Completed
- chlorhexidine gluconate / Generic mfg.
Trial completion, Enrollment change: Diabetic Foot Ulcer. Effectiveness of Chlorhexidine Gluconate 0.125 % Compared With Sterile Deionized Water (clinicaltrials.gov) - Aug 19, 2016
P4, N=24, Completed, Sponsor: Universidad de Guanajuato
Active, not recruiting --> Completed Recruiting --> Completed | N=80 --> 24
- ||||||| Locilex (pexiganan acetate) / PLx Pharma Inc
Trial completion, Head-to-Head: OneStep-2: Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 10, 2016
P3, N=200, Completed, Sponsor: Dipexium Pharmaceuticals, Inc.
Recruiting --> Completed | N=80 --> 24 Recruiting --> Completed
- ||||||| Locilex (pexiganan acetate) / PLx Pharma Inc
Trial completion, Trial primary completion date, Head-to-Head: OneStep-1: Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 10, 2016
P3, N=189, Completed, Sponsor: Dipexium Pharmaceuticals, Inc.
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2016 --> Aug 2016
- |||| Enrollment open, Enrollment change, Trial primary completion date: Efficacy and Safety Study of EscharEx to Treat (Debride) Hard to Heal Wounds (clinicaltrials.gov) - Aug 4, 2016
P2, N=96, Recruiting, Sponsor: MediWound Ltd
Recruiting --> Completed | Trial primary completion date: May 2016 --> Aug 2016 Active, not recruiting --> Recruiting | N=72 --> 96 | Trial primary completion date: Mar 2016 --> Mar 2017
- cenplacel (PDA-002) / Celularity
Trial primary completion date: Study of Human Placenta-derived Cells (PDA002) to Evaluate the Safety and Effectiveness in Subjects With PAD and DFU (clinicaltrials.gov) - Jul 23, 2016
P1, N=15, Active, not recruiting, Sponsor: Celgene Corporation
Active, not recruiting --> Recruiting | N=72 --> 96 | Trial primary completion date: Mar 2016 --> Mar 2017 Trial primary completion date: Mar 2016 --> Sep 2016
- Trial completion: Becaplermin Use and Cancer Risk in a Patient Population of U.S. Veterans With Diabetes (clinicaltrials.gov) - Jul 19, 2016
P=N/A, N=0, Completed, Sponsor: Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Trial primary completion date: Mar 2016 --> Sep 2016 Active, not recruiting --> Completed
- || Enrollment change: Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers (clinicaltrials.gov) - Jul 11, 2016
P=N/A, N=130, Recruiting, Sponsor: MiMedx Group, Inc.
Active, not recruiting --> Completed N=84 --> 130
- Trial primary completion date, Biopsy: Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study (clinicaltrials.gov) - Jun 11, 2016
P=N/A, N=5, Recruiting, Sponsor: Southwest Regional Wound Care Center
N=84 --> 130 Trial primary completion date: Mar 2016 --> Mar 2017
- |||| Trial completion, Enrollment change: A Pilot Trial of the Use of ReCell® Autologous Cell Harvesting Device for Venous Leg Ulcers (clinicaltrials.gov) - Jun 10, 2016
P4, N=52, Completed, Sponsor: Avita Medical
Trial primary completion date: Mar 2016 --> Mar 2017 Recruiting --> Completed | N=65 --> 52
- Trial completion, Trial primary completion date: DFUPS: Diabetic Foot Ulcer Prevention System (clinicaltrials.gov) - Jun 10, 2016
P1, N=105, Completed, Sponsor: King's College Hospital NHS Trust
Recruiting --> Completed | N=65 --> 52 Recruiting --> Completed | Trial primary completion date: Apr 2016 --> Dec 2015
- Trial primary completion date, Real-world evidence, Real-world: A Real World, Observational Registry of Chronic Wounds and Ulcers (clinicaltrials.gov) - May 19, 2016
P=N/A, N=175000, Recruiting, Sponsor: U.S. Wound Registry
Recruiting --> Completed | Trial primary completion date: Apr 2016 --> Dec 2015 Trial primary completion date: Jan 2015 --> Jan 2025
- Trial primary completion date: ANGIOCATH: To Assess Analgesia Provided by Continuous Sciatic Nerve Block in Patients With Hypertensive Leg Ulcer (clinicaltrials.gov) - May 5, 2016
P4, N=30, Recruiting, Sponsor: Nantes University Hospital
Trial primary completion date: Jan 2015 --> Jan 2025 Trial primary completion date: Dec 2016 --> Mar 2018
- gevokizumab (S 78989) / Novartis
Enrollment change, Trial termination, Trial primary completion date: An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum (clinicaltrials.gov) - Apr 27, 2016
P3, N=9, Terminated, Sponsor: XOMA (US) LLC
Trial primary completion date: Dec 2016 --> Mar 2018 N=58 --> 9 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Mar 2016
- gevokizumab (S 78989) / Novartis
Enrollment change, Trial termination, Trial primary completion date: A 2-Year, Open-Label, Safety Extension Study of Gevokizumab in Subjects With Pyoderma Gangrenosum (clinicaltrials.gov) - Apr 27, 2016
P3, N=15, Terminated, Sponsor: XOMA (US) LLC
N=58 --> 9 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Mar 2016 N=100 --> 15 | Enrolling by invitation --> Terminated | Trial primary completion date: Oct 2018 --> Feb 2016
- gevokizumab (S 78989) / Novartis
Enrollment change, Trial termination, Trial primary completion date: An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum (clinicaltrials.gov) - Apr 27, 2016
P3, N=16, Terminated, Sponsor: XOMA (US) LLC
N=100 --> 15 | Enrolling by invitation --> Terminated | Trial primary completion date: Oct 2018 --> Feb 2016 N=58 --> 16 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Mar 2016
- Trial completion: Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (clinicaltrials.gov) - Apr 7, 2016
P=N/A, N=69, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
N=58 --> 16 | Recruiting --> Terminated | Trial primary completion date: Oct 2016 --> Mar 2016 Active, not recruiting --> Completed
- Trial completion: Cooling Lower Leg Skin to Prevent Venous Leg Ulcers in Patients With Poor Vein Circulation (clinicaltrials.gov) - Apr 7, 2016
P1/2, N=197, Completed, Sponsor: Medical University of South Carolina
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion: RGN107: Wound Powder for Pressure Ulcers at End-of-life (clinicaltrials.gov) - Apr 7, 2016
P=N/A, N=50, Completed, Sponsor: Medical University of South Carolina
Recruiting --> Completed Recruiting --> Completed
- aspirin / Generic mfg.
Enrollment closed, Enrollment change, Trial primary completion date: Aspirin for Venous Ulcers: Randomised Trial (AVURT) (clinicaltrials.gov) - Mar 31, 2016
P2, N=26, Active, not recruiting, Sponsor: St George's, University of London
Recruiting --> Completed Recruiting --> Active, not recruiting | N=100 --> 26 | Trial primary completion date: Mar 2016 --> Aug 2016
- Trial completion, Enrollment change: Shockwave Therapy of Chronic Diabetic Foot Ulcers (clinicaltrials.gov) - Mar 30, 2016
P=N/A, N=23, Completed, Sponsor: Odense University Hospital
Recruiting --> Active, not recruiting | N=100 --> 26 | Trial primary completion date: Mar 2016 --> Aug 2016 Recruiting --> Completed | N=30 --> 23