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26 Companies |
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24 Products |
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24 Products |
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22 Mechanisms of Action |
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2 Trials |
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625 News |
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- | Phase classification: LeucoPatch (clinicaltrials.gov) - Apr 24, 2023
P=N/A, N=60, Completed, Sponsor: Reapplix
Phase classification: P4 --> P=N/A
- | Trial completion, Enrollment change: ANGIOCATH: To Assess Analgesia Provided by Continuous Sciatic Nerve Block in Patients With Hypertensive Leg Ulcer (clinicaltrials.gov) - Mar 5, 2019
P4, N=13, Completed, Sponsor: Nantes University Hospital
Phase classification: P4 --> P=N/A Recruiting --> Completed | N=30 --> 13
- | Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Potential Research Study Participant Registry (clinicaltrials.gov) - Feb 16, 2019
P=N/A, N=265, Completed, Sponsor: University of California, Davis
Recruiting --> Completed | N=30 --> 13 Recruiting --> Completed | N=200 --> 265 | Trial completion date: Jan 2025 --> Sep 2018 | Trial primary completion date: Jan 2025 --> Sep 2018
- | Enrollment change, Trial withdrawal: ADA NPWT: Negative Pressure Wound Therapy as a Drug Delivery System (ADANPWT) (clinicaltrials.gov) - Jan 22, 2019
P=N/A, N=0, Withdrawn, Sponsor: University of Texas Southwestern Medical Center
Recruiting --> Completed | N=200 --> 265 | Trial completion date: Jan 2025 --> Sep 2018 | Trial primary completion date: Jan 2025 --> Sep 2018 N=150 --> 0 | Recruiting --> Withdrawn
- | Trial completion, Trial completion date, Trial primary completion date, Biopsy: Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study (clinicaltrials.gov) - Jan 14, 2019
P=N/A, N=48, Completed, Sponsor: Southwest Regional Wound Care Center
N=150 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | Trial completion date: Mar 2020 --> Dec 2018 | Trial primary completion date: Mar 2020 --> Dec 2018
- | cefazolin / Generic mfg.
Phase classification: DAD: Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion (clinicaltrials.gov) - Oct 24, 2018
P=N/A, N=0, No Longer Available, Sponsor: Sonescence, Inc.
Recruiting --> Completed | Trial completion date: Mar 2020 --> Dec 2018 | Trial primary completion date: Mar 2020 --> Dec 2018 Phase classification: P1 --> P=N/A
- | Trial completion date: Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders (clinicaltrials.gov) - Oct 16, 2018
P1, N=28, Completed, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Phase classification: P1 --> P=N/A Trial completion date: Sep 2015 --> Oct 2018
- | Trial completion, Trial completion date, Trial primary completion date: Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers (clinicaltrials.gov) - Sep 24, 2018
P=N/A, N=132, Completed, Sponsor: MiMedx Group, Inc.
Trial completion date: Sep 2015 --> Oct 2018 Recruiting --> Completed | Trial completion date: Oct 2017 --> Jun 2018 | Trial primary completion date: May 2017 --> Jun 2018
- | Trial completion, Trial completion date, Trial primary completion date: Efficacy and Safety Study of EscharEx to Treat (Debride) Hard to Heal Wounds (clinicaltrials.gov) - Sep 1, 2018
P2, N=111, Completed, Sponsor: MediWound Ltd
Recruiting --> Completed | Trial completion date: Oct 2017 --> Jun 2018 | Trial primary completion date: May 2017 --> Jun 2018 Recruiting --> Completed | Trial completion date: Jun 2017 --> Jun 2018 | Trial primary completion date: Mar 2017 --> Dec 2017
- | Trial completion, Trial completion date: Use of dHACM in the Treatment of Venous Leg Ulcers (clinicaltrials.gov) - Aug 24, 2018
P=N/A, N=128, Completed, Sponsor: MiMedx Group, Inc.
Recruiting --> Completed | Trial completion date: Jun 2017 --> Jun 2018 | Trial primary completion date: Mar 2017 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Jul 2017 --> Nov 2017
- | Enrollment change: Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity Ulcers (clinicaltrials.gov) - Aug 14, 2018
P=N/A, N=5, Terminated, Sponsor: De La Salle University Medical Center
Active, not recruiting --> Completed | Trial completion date: Jul 2017 --> Nov 2017 N=50 --> 5
- | Enrollment change: Wheels: Outcome Measures for Pediatric Wheelchairs in Low-resource Settings (clinicaltrials.gov) - Jul 19, 2018
P=N/A, N=100, Terminated, Sponsor: Bethany Relief and Rehabilitation International Inc.
N=50 --> 5 N=20 --> 100
- | Trial completion date, Trial primary completion date, Biopsy: Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study (clinicaltrials.gov) - Jun 29, 2018
P=N/A, N=5, Recruiting, Sponsor: Southwest Regional Wound Care Center
N=20 --> 100 Trial completion date: Mar 2019 --> Mar 2020 | Trial primary completion date: Mar 2019 --> Mar 2020
- | Enrollment change, Trial termination: SAS-FOOT: Impact of Sleep Apnea on Diabetic Foot Wound. (clinicaltrials.gov) - Jun 28, 2018
P=N/A, N=35, Terminated, Sponsor: AGIR à Dom
Trial completion date: Mar 2019 --> Mar 2020 | Trial primary completion date: Mar 2019 --> Mar 2020 N=60 --> 35 | Recruiting --> Terminated; Difficulty including subjects corresponding to the criteria.
- | Trial completion: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers (clinicaltrials.gov) - Jun 25, 2018
P4, N=269, Completed, Sponsor: Nottingham University Hospitals NHS Trust
N=60 --> 35 | Recruiting --> Terminated; Difficulty including subjects corresponding to the criteria. Active, not recruiting --> Completed
- | Enrollment change, Trial withdrawal, Trial primary completion date: A Randomized, Prospective Clinical Trial of Immediate Flap Closure Versus Wound Care for Management of Late-stage Pressure Ulcers (clinicaltrials.gov) - Jun 12, 2018
P=N/A, N=0, Withdrawn, Sponsor: Santa Barbara Cottage Hospital
Active, not recruiting --> Completed N=50 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Jun 2018
- | Trial completion, Enrollment change: Osteomyelitis: Procalcitonin to Diagnose and Monitor Osteomyelitis (clinicaltrials.gov) - Jun 8, 2018
P=N/A, N=36, Completed, Sponsor: University of Texas Southwestern Medical Center
N=50 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Jun 2018 Not yet recruiting --> Completed | N=80 --> 36
- | Trial completion, Enrollment change: AIRPEDIA: Medico-economical Assessment of Telemedicine During Chronic Diabetes-related Foot Wound Management (clinicaltrials.gov) - Jun 1, 2018
P2/3, N=14, Completed, Sponsor: University Hospital, Grenoble
Not yet recruiting --> Completed | N=80 --> 36 Active, not recruiting --> Completed | N=64 --> 14
- | Trial completion: The Pharmacokinetic Study of WH-1 Ointment in Subjects With Chronic Diabetic Foot Ulcers (clinicaltrials.gov) - Mar 30, 2018
P1, N=12, Completed, Sponsor: Oneness Biotech Co., Ltd.
Active, not recruiting --> Completed | N=64 --> 14 Recruiting --> Completed
- | Phase classification: DermACELL in Subjects With Chronic Wounds of the Lower Extremities (clinicaltrials.gov) - Mar 14, 2018
P=N/A, N=202, Completed, Sponsor: LifeNet Health
Recruiting --> Completed Phase classification: P4 --> P=N/A
- | Trial completion, Trial primary completion date: Evaluation of Fluorescence-image Guided Wound Assessment vs. Standard Practice (clinicaltrials.gov) - Feb 13, 2018
P=N/A, N=80, Completed, Sponsor: University Health Network, Toronto
Phase classification: P4 --> P=N/A Enrolling by invitation --> Completed | Trial primary completion date: Dec 2015 --> Jan 2017
- Trial termination, Trial primary completion date: CMS: Registry Trial of the Effectiveness of Platelet Rich Plasma for Chronic Non-Healing Wounds (clinicaltrials.gov) - Jan 16, 2018
P=N/A, N=1500, Terminated, Sponsor: Arteriocyte, Inc.
Enrolling by invitation --> Completed | Trial primary completion date: Dec 2015 --> Jan 2017 Recruiting --> Terminated | Trial primary completion date: Mar 2021 --> Jan 2018
- | Trial primary completion date, Biopsy: Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study (clinicaltrials.gov) - Jan 2, 2018
P=N/A, N=5, Recruiting, Sponsor: Southwest Regional Wound Care Center
Recruiting --> Terminated | Trial primary completion date: Mar 2021 --> Jan 2018 Trial primary completion date: Mar 2018 --> Mar 2019
- | Phase classification: Biatain Ag vs Biatain in the Treament of Leg Ulcers (clinicaltrials.gov) - Dec 20, 2017
P=N/A, N=182, Completed, Sponsor: Coloplast A/S
Trial primary completion date: Mar 2018 --> Mar 2019 Phase classification: P4 --> P=N/A
- | Enrollment change, Trial initiation date, Trial termination, Trial primary completion date: STRIDE 5: Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use (clinicaltrials.gov) - Dec 12, 2017
P3, N=261, Terminated, Sponsor: Integra LifeSciences Corporation
Phase classification: P4 --> P=N/A N=200 --> 261 | Initiation date: Jun 2013 --> Dec 2015 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2016 --> Dec 2015
- | Enrollment change, Trial termination, Trial primary completion date: STRIDE 1: Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers (clinicaltrials.gov) - Dec 12, 2017
P3, N=266, Terminated, Sponsor: Integra LifeSciences Corporation
N=200 --> 261 | Initiation date: Jun 2013 --> Dec 2015 | Active, not recruiting --> Terminated | Trial primary completion date: Jun 2016 --> Dec 2015 Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Dec 2015 | N=422 --> 266
- | Enrollment change, Trial termination, Trial primary completion date: STRIDE 2: Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers (clinicaltrials.gov) - Dec 12, 2017
P3, N=396, Terminated, Sponsor: Integra LifeSciences Corporation
Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Dec 2015 | N=422 --> 266 N=633 --> 396 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Dec 2015
- | Enrollment closed: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers (clinicaltrials.gov) - Dec 7, 2017
P4, N=269, Active, not recruiting, Sponsor: Nottingham University Hospitals NHS Trust
N=633 --> 396 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Dec 2015 Recruiting --> Active, not recruiting
- Phase classification: Phase IV Study to Evaluate the Efficacy of AMNIOEXCEL in Diabetic Foot Ulcers (clinicaltrials.gov) - Dec 2, 2017
P=N/A, N=29, Completed, Sponsor: Integra LifeSciences Corporation
Recruiting --> Active, not recruiting Phase classification: P4 --> P=N/A
- | Phase classification: Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS) (clinicaltrials.gov) - Nov 29, 2017
P=N/A, N=12, Completed, Sponsor: University of North Carolina, Chapel Hill
Phase classification: P4 --> P=N/A Phase classification: P2 --> P=N/A
- |||| Epicyn / Sonoma Pharma, Amneal
Trial completion: Pressure Ulcer Healing With Microcyn (clinicaltrials.gov) - Oct 9, 2017
P4, N=65, Completed, Sponsor: University of Alabama at Birmingham
Phase classification: P2 --> P=N/A Recruiting --> Completed
- | Trial completion, Trial primary completion date: LASER-1: Laser Therapy for Onychomycosis in Patients Wih Diabetes at Risk for Diabetic Foot Complications (clinicaltrials.gov) - Sep 1, 2017
P=N/A, N=64, Completed, Sponsor: Medical Research Foundation, The Netherlands
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Jul 2017
- ||||||| Trial completion: ADHOC: The Sorbact® Antimicrobial Dressing in the Holistic Wound Management Of Diabetic Foot ulCers (Phase III Study) (clinicaltrials.gov) - Aug 31, 2017
P3, N=200, Completed, Sponsor: INRESA Pharma
Active, not recruiting --> Completed | Trial primary completion date: Mar 2017 --> Jul 2017 Active, not recruiting --> Completed
- | Enrollment change: CLUE Study: Connective Tissue Disease Leg Ulcer Etiology Study (clinicaltrials.gov) - Aug 30, 2017
P=N/A, N=40, Completed, Sponsor: George Washington University
Active, not recruiting --> Completed N=300 --> 40
- Trial termination: A Study With Primatrix Dermal Repair Scaffold For The Treatment Of Diabetic Foot Ulcers (clinicaltrials.gov) - Aug 10, 2017
P=N/A, N=30, Terminated, Sponsor: Integra LifeSciences Corporation
N=300 --> 40 Suspended --> Terminated; Business Decision
- Trial termination: A Multi-center, Prospective, Randomized Study With PriMatrix and PriMatrix Ag for the Treatment of Venous Leg Ulcers (clinicaltrials.gov) - Aug 8, 2017
P=N/A, N=31, Terminated, Sponsor: Integra LifeSciences Corporation
Suspended --> Terminated; Business Decision Suspended --> Terminated; Site selection
- ||||||| Trial completion, Enrollment change, Trial primary completion date: Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2 (clinicaltrials.gov) - Jul 26, 2017
P3, N=155, Completed, Sponsor: Healthpoint
Suspended --> Terminated; Site selection Active, not recruiting --> Completed | N=250 --> 155 | Trial primary completion date: Apr 2015 --> Nov 2015
- | Phase classification, Enrollment change, Trial primary completion date: Treatment of the Hypertensive Leg Ulcers by PRF Application (clinicaltrials.gov) - Jul 2, 2017
P4, N=10, Terminated, Sponsor: University Hospital, Strasbourg, France
Active, not recruiting --> Completed | N=250 --> 155 | Trial primary completion date: Apr 2015 --> Nov 2015 Phase classification: P2 --> P4 | N=18 --> 10 | Trial primary completion date: Jul 2015 --> Jul 2017
- ||||||| Trial completion, Trial primary completion date: A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer (clinicaltrials.gov) - Jun 29, 2017
P3, N=252, Completed, Sponsor: Adocia
Phase classification: P2 --> P4 | N=18 --> 10 | Trial primary completion date: Jul 2015 --> Jul 2017 Recruiting --> Completed | Trial primary completion date: Sep 2015 --> Aug 2016
- | aspirin / Generic mfg.
Trial termination: Aspirin for Venous Ulcers: Randomised Trial (AVURT) (clinicaltrials.gov) - Jun 27, 2017
P2, N=26, Terminated, Sponsor: St George's, University of London
Active, not recruiting --> Terminated; Recruitment halted following TSC meeting due to poor recruitment and study unlikely to complete. Funders withdrew continued support
- Enrollment change, Trial termination, Trial primary completion date: CONDUCT I: NEOX® CORD 1K vs Standard of Care in Non-healing Diabetic Foot Ulcers (clinicaltrials.gov) - Jun 27, 2017
P=N/A, N=18, Terminated, Sponsor: Amniox Medical, Inc.
Funders withdrew continued support N=30 --> 18 | Recruiting --> Terminated | Trial primary completion date: Jun 2016 --> Jun 2015; Sponsor decision
- | Phase classification: Observational Study Providing 12 Months of Safety Follow-Up From First Exposure to HP802-247 (clinicaltrials.gov) - Jun 22, 2017
P=N/A, N=221, Completed, Sponsor: Healthpoint
N=30 --> 18 | Recruiting --> Terminated | Trial primary completion date: Jun 2016 --> Jun 2015; Sponsor decision Phase classification: P3 --> P=N/A
- ||||||| Trial completion, Enrollment change, Trial primary completion date: Observational Study Providing 12 Months of Safety Follow-Up From First Exposure to HP802-247 (clinicaltrials.gov) - Jun 5, 2017
P3, N=221, Completed, Sponsor: Healthpoint
Phase classification: P3 --> P=N/A Active, not recruiting --> Completed | N=440 --> 221 | Trial primary completion date: Feb 2016 --> Nov 2015
- ||| Trial completion, Trial primary completion date: ORTHODIAB: Evaluation of a New Device "Orth (clinicaltrials.gov) - Jun 1, 2017
P=N/A, N=118, Completed, Sponsor: Proteor Group
Active, not recruiting --> Completed | N=440 --> 221 | Trial primary completion date: Feb 2016 --> Nov 2015 Recruiting --> Completed | Trial primary completion date: May 2016 --> Nov 2016
- Enrollment change, Trial initiation date, Trial withdrawal, Trial primary completion date: A Prospective Randomized, Double-Blind, Placebo-Controlled Trial Comparing VitroGro (clinicaltrials.gov) - May 30, 2017
P2/3, N=0, Withdrawn, Sponsor: Tissue Therapies Ltd.
Recruiting --> Completed | Trial primary completion date: May 2016 --> Nov 2016 N=250 --> 0 | Initiation date: Jan 2016 --> Jan 2017 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2017 --> Jun 2018
- | Trial completion, Trial initiation date, Trial primary completion date: The Effectiveness of a Pressure Ulcer Prevention Programme for Older People in For-profit Private Nursing Homes (clinicaltrials.gov) - May 24, 2017
P=N/A, N=1013, Completed, Sponsor: The Hong Kong Polytechnic University
N=250 --> 0 | Initiation date: Jan 2016 --> Jan 2017 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jun 2017 --> Jun 2018 Not yet recruiting --> Completed | Initiation date: Jan 2015 --> Nov 2015 | Trial primary completion date: Jan 2016 --> Sep 2016
- | Trial primary completion date, Biopsy: Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study (clinicaltrials.gov) - May 11, 2017
P=N/A, N=5, Recruiting, Sponsor: Southwest Regional Wound Care Center
Not yet recruiting --> Completed | Initiation date: Jan 2015 --> Nov 2015 | Trial primary completion date: Jan 2016 --> Sep 2016 Trial primary completion date: Mar 2017 --> Mar 2018
- | Trial completion: A Study Evaluating Topical Recombinant Human Vascular Endothelial Growth Factor (Telbermin) for Induction of Healing of Chronic, Diabetic Foot Ulcers (clinicaltrials.gov) - May 10, 2017
P1, N=50, Completed, Sponsor: Genentech, Inc.
Trial primary completion date: Mar 2017 --> Mar 2018 No longer recruiting --> Completed
- | aspirin / Generic mfg.
Trial completion, Enrollment change: Low Dose Aspirin for Venous Leg Ulcers (clinicaltrials.gov) - May 3, 2017
P3, N=251, Completed, Sponsor: University of Auckland, New Zealand
No longer recruiting --> Completed Recruiting --> Completed | N=354 --> 251
- | Enrollment change, Trial termination, Trial primary completion date: Transcutaneous Raman Spectroscope (TRS) Analyses of Diabetic Foot Ulcers (clinicaltrials.gov) - Apr 19, 2017
P=N/A, N=5, Terminated, Sponsor: University of Michigan
Recruiting --> Completed | N=354 --> 251 N=30 --> 5 | Suspended --> Terminated | Trial primary completion date: Aug 2017 --> Nov 2014; TRS probe performance does not meet primary outcome data requirements