Skin Neoplasms MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	3	6	9	12	15	18	21	24	27	30



Immunostimulant




EGFR inhib




Alkylating agent




BRAF V600E inhib




IFNα stim




EGFR mutation inhib




Immunosuppressant




PDGFR β inhib




VEGF inhib




c-KIT inhib




CD8 T-cell agon




DNA synthesis inhib




HIF-1 inhib




IGF-1R inhib




MEK2 inhib




MEK2 inhib




TNF inhib




Tubulin inhib




mTOR inhib




Acetylcholine inhib




BRAF V600E inhib




Bcl2 inhib




Bcl2 inhib




CTLA4 inhib




Calcineurin inhib




HER2 inhib




HIF-1 inhib




Histamine H1 receptor antag




IL-2 stim




IL-2 stim




IMPDH inhib




Protease inhib




Retinoic acid receptor agon




T-cell activation inhib




TLR8 agon




Tumor-associated antigen inhib




AKT inhib




Apoptosis stim




Bone morphogenetic protein receptor type II mod




COX2 inhib




DGAT inhib




Fatty acid inhib




Fyn inhib




GD3 ganglioside inhib




GM-CSF agon




GM-CSF agon




Glutamate receptor antag




GnRH agon




GnRH agon




Hedgehog cell-signalling pathway inhib



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