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74 Companies |
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57 Products |
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57 Products |
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42 Mechanisms of Action |
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2 Trials |
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680 News |
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- Trial completion, Trial primary completion date, IO biomarker: A Study to Explore Association of Treatment Regimens for Visceral Leishmaniasis, Host Immunological, Genetical and Nutrition Factors With Post-kala-azar Dermal Leishmaniasis (PKDL) (clinicaltrials.gov) - Nov 5, 2014
P4, N=36, Completed, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
Active, not recruiting --> Completed | Trial primary completion date: Dec 2013 --> Sep 2014
- Remicade (infliximab) / Merck (MSD), Mitsubishi Tanabe, J&J
Enrollment open: Topical Infliximab in Autoimmune Eyes With Keratoprosthesis (clinicaltrials.gov) - Nov 4, 2014
P1/2, N=4, Enrolling by invitation, Sponsor: James Chodosh, MD, MPH
Active, not recruiting --> Completed | Trial primary completion date: Dec 2013 --> Sep 2014 Not yet recruiting --> Enrolling by invitation
- Tembexa (brincidofovir oral) / SymBio Pharma
Trial initiation date: A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease) (clinicaltrials.gov) - Oct 30, 2014
P1/2, N=32, Not yet recruiting, Sponsor: University of Alabama at Birmingham
Not yet recruiting --> Enrolling by invitation Initiation date: Jul 2013 --> Dec 2014
- Trial primary completion date: Protocol TARC-ABPA (clinicaltrials.gov) - Oct 22, 2014
P=N/A, N=30, Recruiting, Sponsor: Nantes University Hospital
Initiation date: Jul 2013 --> Dec 2014 Trial primary completion date: Nov 2016 --> May 2017
- Clinical: Evaluation of an Oligonucleotide Array for Rapid Identification of Dermatophytes in Clinical Specimens (clinicaltrials.gov) - Oct 22, 2014
P=N/A, N=32, Completed, Sponsor: National Cheng-Kung University Hospital
- ||| Clinical: Evaluation of the HSV 1 & 2 Assay in Specimens From Symptomatic Subjects (clinicaltrials.gov) - Oct 22, 2014
P=N/A, N=1900, Not yet recruiting, Sponsor: Hologic, Inc.
- ||| Enrollment open: A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease (clinicaltrials.gov) - Oct 22, 2014
P=N/A, N=89, Recruiting, Sponsor: St. Jude Children's Research Hospital
Trial primary completion date: Nov 2016 --> May 2017 Not yet recruiting --> Recruiting
- azithromycin / Generic mfg.
Enrollment change, Trial termination: PCL01: Safety and Efficacy of Azithromycin to Treat Cutaneous Leishmaniasis (clinicaltrials.gov) - Oct 17, 2014
P2/3, N=48, Terminated, Sponsor: Ana Rabello
Not yet recruiting --> Recruiting N=620 --> 48 | Recruiting --> Terminated; Efficacy issues on test arm
- |||| luliconazole 10% solution (SKX-16) / Sato Pharma, Bausch Health
Trial completion: Safety and Efficacy of Luliconazole Solution, 10% in Subjects With Mild to Moderate Onychomycosis (clinicaltrials.gov) - Oct 11, 2014
P2b, N=334, Completed, Sponsor: Topica Pharmaceuticals
N=620 --> 48 | Recruiting --> Terminated; Efficacy issues on test arm Active, not recruiting --> Completed
- | valacyclovir / Generic mfg.
Enrollment change, Trial primary completion date: Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals? (clinicaltrials.gov) - Oct 10, 2014
P3, N=230, Recruiting, Sponsor: University Health Network, Toronto
Active, not recruiting --> Completed N=480 --> 230 | Trial primary completion date: Feb 2015 --> Feb 2016
- ||| AMG 108 / AstraZeneca
Enrollment change: Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa (clinicaltrials.gov) - Oct 2, 2014
P2a, N=100, Active, not recruiting, Sponsor: AstraZeneca
N=480 --> 230 | Trial primary completion date: Feb 2015 --> Feb 2016 N=224 --> 100
- | amphotericin b liposome / Generic mfg.
Enrollment open, Combination therapy, Monotherapy: Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. (clinicaltrials.gov) - Sep 29, 2014
P3, N=132, Recruiting, Sponsor: Drugs for Neglected Diseases
N=224 --> 100 Not yet recruiting --> Recruiting
- |||| Lenocta (sodium stibogluconate) / VioQuest
Trial completion: Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa (clinicaltrials.gov) - Sep 29, 2014
P2, N=183, Completed, Sponsor: Drugs for Neglected Diseases
Not yet recruiting --> Recruiting Recruiting --> Completed
- |||| Naftin (naftifine hydrochloride) / Merz Pharma
Enrollment open: Pediatric Subjects With Tinea Corporis (clinicaltrials.gov) - Sep 28, 2014
P4, N=318, Recruiting, Sponsor: Merz Pharmaceuticals, LLC
Recruiting --> Completed Not yet recruiting --> Recruiting
- ||| thimerosal (BTL-TML) / Beech Tree Labs
Enrollment closed: Evaluation of Cold Sore Treatments on Ultra Violet (UV) Induced Cold Sores (clinicaltrials.gov) - Sep 28, 2014
P2, N=250, Active, not recruiting, Sponsor: Beech Tree Labs, Inc.
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion, Trial primary completion date: An Open,Single-centre Pilot Study of Efficacy and Safety of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO) (clinicaltrials.gov) - Sep 22, 2014
P2, N=0, Completed, Sponsor: Moberg Derma AB
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | Trial primary completion date: Oct 2014 --> Jul 2014
- | acyclovir / Generic mfg.
Trial completion: Acyclovir in Preventing Herpes Simplex Virus Infection in Patients With Neutropenia (clinicaltrials.gov) - Sep 19, 2014
P3, N=112, Completed, Sponsor: Comprehensive Cancer Center of Wake Forest University
Active, not recruiting --> Completed | Trial primary completion date: Oct 2014 --> Jul 2014 Active, not recruiting --> Completed
- New P2 trial, Preclinical: KR: Evaluation of Preclinical Toxicity andTherapeutic Efficacy of Kandhaga Rasayanam in Padarthamarai (clinicaltrials.gov) - Sep 12, 2014
P2, N=50, Completed, Sponsor: National institute of Siddha
- Enrollment open: A Clinical Investigation to Evaluate the Safety and Performance of a Treatment Kit for Ingrowing Toenail (clinicaltrials.gov) - Sep 12, 2014
P=N/A, N=36, Recruiting, Sponsor: Reckitt Benckiser Healthcare (UK) Limited
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | tigecycline / Generic mfg.
Phase classification: TIGER: Tygacil Drug Use Investigation (clinicaltrials.gov) - Sep 11, 2014
P=N/A, N=100, Enrolling by invitation, Sponsor: Pfizer
Not yet recruiting --> Recruiting Phase classification: P4 --> P=N/A
- ||| Trial completion: Evaluation of CL Detect™ Rapid Test to Detect Cutaneous Leishmaniasis (clinicaltrials.gov) - Sep 8, 2014
P=N/A, N=150, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Phase classification: P4 --> P=N/A Active, not recruiting --> Completed
- ||| Trial completion, Trial primary completion date: CL Detect™: Evaluation of a Rapid Diagnostic Device, CL Detect, for the Diagnosis of Cutaneous Leishmaniasis in Tunisia (clinicaltrials.gov) - Sep 8, 2014
P=N/A, N=150, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Mar 2013 --> Aug 2013
- Clinical: Predictors of Oral Antibiotic Treatment Failure in Emergency Department Patients With Cellulitis (clinicaltrials.gov) - Sep 4, 2014
P=N/A, N=139, Not yet recruiting, Sponsor: Royal College of Surgeons, Ireland
- ||||| Naftin (naftifine hydrochloride) / Merz Pharma
New P4 trial: Pediatric Subjects With Tinea Corporis (clinicaltrials.gov) - Aug 29, 2014
P4, N=318, Not yet recruiting, Sponsor: Merz Pharmaceuticals, LLC
- ||| Enrollment closed: Efficacy and Safety Study of ME1111 in Patients With Onychomycosis (clinicaltrials.gov) - Aug 28, 2014
P2, N=300, Active, not recruiting, Sponsor: Meiji Seika Pharma Co., Ltd.
Recruiting --> Completed | Trial primary completion date: Mar 2013 --> Aug 2013 Recruiting --> Active, not recruiting
- gentamicin sulfate / Generic mfg.
Trial primary completion date: Safety, Efficacy and Pharmacokinetics (PK) Study of WR 279,396 Versus Paromomycin for Treatment of Cutaneous Leishmaniasis (Peru-PK) (clinicaltrials.gov) - Aug 22, 2014
P2, N=30, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
Recruiting --> Active, not recruiting Trial primary completion date: Jul 2011 --> Mar 2011
- ||| brilacidin (PMX-30063) / Innovation Pharma
Enrollment closed: Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infections (clinicaltrials.gov) - Aug 22, 2014
P2, N=215, Active, not recruiting, Sponsor: Cellceutix Corporation
Trial primary completion date: Jul 2011 --> Mar 2011 Enrolling by invitation --> Active, not recruiting
- || thimerosal (BTL-TML) / Beech Tree Labs
Trial primary completion date: Evaluation of Cold Sore Treatments on Ultra Violet (UV) Induced Cold Sores (clinicaltrials.gov) - Aug 21, 2014
P2, N=250, Recruiting, Sponsor: Beech Tree Labs, Inc.
Enrolling by invitation --> Active, not recruiting Trial primary completion date: Jun 2014 --> Oct 2014
- Trial primary completion date: UARK 2009-99 A Non-interventional Observational Study of Infectious Complications in Cancer Patients (clinicaltrials.gov) - Aug 21, 2014
P=N/A, N=600, Recruiting, Sponsor: University of Arkansas
Trial primary completion date: Jun 2014 --> Oct 2014 Trial primary completion date: Nov 2014 --> Dec 2015
- Olorofim (orotomide) / F2G
Enrollment open: F901318 Single Ascending Dose Study in Healthy Male Volunteers (clinicaltrials.gov) - Aug 15, 2014
P1, N=40, Recruiting, Sponsor: F2G Ltd.
Trial primary completion date: Nov 2014 --> Dec 2015 Not yet recruiting --> Recruiting
- Altabax (retapamulin) / GSK, Almirall
Trial completion: Retapamulin Microdialysis Feasibility Study (clinicaltrials.gov) - Aug 15, 2014
P1, N=3, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | Enrollment change: Safety and Tolerability of a Novel Malathion Formulation in Children Age 6-24 Months With Head Lice (clinicaltrials.gov) - Aug 7, 2014
P2/3, N=12, Completed, Sponsor: Taro Pharmaceuticals USA
Active, not recruiting --> Completed N=30 --> 12
- ||| Trial completion, Trial primary completion date: Human Papillomavirus (HPV) Types Present in External Genital Warts (EGW) in the Argentinean Population (clinicaltrials.gov) - Aug 7, 2014
P=N/A, N=150, Completed, Sponsor: University of Buenos Aires
N=30 --> 12 Recruiting --> Completed | Trial primary completion date: Jun 2013 --> Aug 2014
- Trial primary completion date: Pulsed Dye Laser Treatment of Onychomycosis (clinicaltrials.gov) - Aug 6, 2014
P=N/A, N=10, Recruiting, Sponsor: Thomas Jefferson University
Recruiting --> Completed | Trial primary completion date: Jun 2013 --> Aug 2014 Trial primary completion date: May 2014 --> Dec 2014
- |||||||||| Amenalief (amenamevir) / Maruho
New P3 trial: Open-label Study of ASP2151 in Herpes Simplex Patients (clinicaltrials.gov) - Aug 5, 2014
P3, N=250, Recruiting, Sponsor: Maruho Co., Ltd.
- ||||| Enrollment change: Efficacy, Safety and Tolerability of a Novel Malathion Formulation in Patients 2 Years and Older With Head Lice (clinicaltrials.gov) - Aug 4, 2014
P3, N=254, Completed, Sponsor: Taro Pharmaceuticals USA
Trial primary completion date: May 2014 --> Dec 2014 N=95 --> 254
- | New P2 trial: A Double-Blind, Randomized, Placebo-Controlled Study of Topical VDO for the Treatment of Herpes Simplex Labialis (clinicaltrials.gov) - Aug 4, 2014
P2, N=40, Recruiting, Sponsor: Yung Shin Pharm. Ind. Co., Ltd.
- flucloxacillin sodium / Generic mfg.
Enrollment open, Trial initiation date: DANCE: Duration of ANtibiotic Therapy for CEllulitis (clinicaltrials.gov) - Aug 4, 2014
P4, N=396, Recruiting, Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
N=95 --> 254 Not yet recruiting --> Recruiting | Initiation date: Feb 2014 --> Aug 2014
- | CIGB-300 / Center for Genetic Engineering and Biotechnology
Trial termination: Recurrent and Nonrecurrent Condyloma Treatment (clinicaltrials.gov) - Aug 1, 2014
P2/3, N=132, Terminated, Sponsor: Laboratorio Elea S.A.C.I.F. y A.
Not yet recruiting --> Recruiting | Initiation date: Feb 2014 --> Aug 2014 Recruiting --> Terminated
- Cubicin (daptomycin) / Merck (MSD)
Trial completion, Trial primary completion date: Evaluation of Daptomycin for the Emergency Department Treatment of Complicated Skin and Skin Structure Infections (clinicaltrials.gov) - Aug 1, 2014
P4, N=104, Completed, Sponsor: University of Cincinnati
Recruiting --> Terminated Recruiting --> Completed | Trial primary completion date: Apr 2014 --> Jul 2013
- ||||||| aztreonam / Generic mfg., vancomycin / Generic mfg., ceftaroline fosamil / Generic mfg.
Trial completion: Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections (clinicaltrials.gov) - Jul 30, 2014
P3, N=801, Completed, Sponsor: AstraZeneca
Recruiting --> Completed | Trial primary completion date: Apr 2014 --> Jul 2013 Recruiting --> Completed
- |||||||||| aztreonam / Generic mfg., vancomycin / Generic mfg., ceftaroline fosamil / Generic mfg.
New P3 trial: Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections. (clinicaltrials.gov) - Jul 29, 2014
P3, N=60, Recruiting, Sponsor: AstraZeneca
- ||| AMG 108 / AstraZeneca
Enrollment change: Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa (clinicaltrials.gov) - Jul 23, 2014
P2a, N=224, Active, not recruiting, Sponsor: AstraZeneca
Recruiting --> Completed N=100 --> 224
- |||| HSV vaccine (GEN-003) / Genocea, Shionogi
Enrollment open: Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine (clinicaltrials.gov) - Jul 23, 2014
P2, N=315, Recruiting, Sponsor: Genocea Biosciences, Inc.
N=100 --> 224 Not yet recruiting --> Recruiting
- | acyclovir / Generic mfg.
Phase classification: An Exploratory Study to Investigate the Inflammatory Response During a Cold Sore Episode (clinicaltrials.gov) - Jul 16, 2014
P1, N=60, Completed, Sponsor: GlaxoSmithKline
Not yet recruiting --> Recruiting Phase classification: P2 --> P1
- ||||||| Baxdela (delafloxacin) / Menarini, Melinta Therap
Trial completion: Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections (clinicaltrials.gov) - Jul 15, 2014
P3, N=660, Completed, Sponsor: Melinta Therapeutics, Inc.
Phase classification: P2 --> P1 Recruiting --> Completed
- Trial primary completion date: Replacement of Insecticides to Control Visceral Leishmaniasis (VL) (clinicaltrials.gov) - Jul 12, 2014
P3, N=3600, Recruiting, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
Recruiting --> Completed Trial primary completion date: Dec 2013 --> Dec 2014
- Trial primary completion date: Registry for the Atopic Dermatitis Research Network (clinicaltrials.gov) - Jul 12, 2014
P=N/A, N=2600, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Trial primary completion date: Dec 2013 --> Dec 2014 Trial primary completion date: Jun 2014 --> Dec 2014
- | amphotericin b liposome / Generic mfg.
Trial initiation date, Trial primary completion date, Combination therapy, Monotherapy: Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. (clinicaltrials.gov) - Jul 12, 2014
P3, N=132, Not yet recruiting, Sponsor: Drugs for Neglected Diseases
Trial primary completion date: Jun 2014 --> Dec 2014 Initiation date: Dec 2013 --> Jul 2014 | Trial primary completion date: Jun 2015 --> Jan 2016
- Trial primary completion date: Evaluation of Exhaled Breath Condensate in the Diagnosis of Invasive Pulmonary Aspergillosis (clinicaltrials.gov) - Jul 8, 2014
P=N/A, N=24, Completed, Sponsor: Universitaire Ziekenhuizen Leuven
Initiation date: Dec 2013 --> Jul 2014 | Trial primary completion date: Jun 2015 --> Jan 2016 Trial primary completion date: Jun 2013 --> Jul 2014