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13 Companies |
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19 Products |
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19 Products |
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12 Mechanisms of Action |
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0 Trials |
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229 News |
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- Trial completion, Surgery: Safety and Performance of the Steroid-Releasing S8 Sinus Implant (clinicaltrials.gov) - Oct 27, 2013
P3, N=5, Completed, Sponsor: Intersect ENT
Active, not recruiting --> Completed
- epinephrine / Generic mfg.
Enrollment open, Surgery: Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery (clinicaltrials.gov) - Oct 22, 2013
P4, N=45, Recruiting, Sponsor: Marc Tewfik
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- amoxycillin/clavulanate / Generic mfg.
Trial completion: Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis (clinicaltrials.gov) - Oct 5, 2013
P=N/A, N=50, Completed, Sponsor: Ohad Ronen
Not yet recruiting --> Recruiting Recruiting --> Completed
- || Enrollment change: Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose (clinicaltrials.gov) - Sep 26, 2013
P=N/A, N=96, Completed, Sponsor: Carestream Health, Inc.
Recruiting --> Completed N=175 --> 96
- ||| Trial completion: Cone Beam CT for Diagnosis of Select Otorhinolaryngology (ENT) Indications at Lower Dose (clinicaltrials.gov) - Sep 26, 2013
P=N/A, N=96, Completed, Sponsor: Carestream Health, Inc.
N=175 --> 96 Enrolling by invitation --> Completed
- |||||| Enrollment open: Study Evaluating the Safety of Intranasal Administration of 400 ?g of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps (clinicaltrials.gov) - Sep 18, 2013
P3, N=700, Recruiting, Sponsor: Optinose US Inc.
Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
- |||||| Xhance (fluticasone propionate intranasal spray) / OptiNose
Enrollment open: 12-Month OL Intranasal Fluticasone Propionate BID Using OptiNose Device (clinicaltrials.gov) - Sep 18, 2013
P3, N=200, Recruiting, Sponsor: Optinose US Inc.
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- prednisone / Generic mfg.
Trial completion: Effect of Prednisone onTregs and TH17 (clinicaltrials.gov) - Sep 3, 2013
P1, N=40, Completed, Sponsor: University of Chicago
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||| amoxycillin/clavulanate / Generic mfg.
New P3 trial: Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis (clinicaltrials.gov) - Sep 2, 2013
P3, N=27, Completed, Sponsor: GlaxoSmithKline
- |||| Dupixent (dupilumab) / Sanofi, Regeneron
Enrollment open: An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis (clinicaltrials.gov) - Aug 29, 2013
P2, N=56, Recruiting, Sponsor: Sanofi
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open, Surgery: Hot Saline Irrigation Study (clinicaltrials.gov) - Aug 27, 2013
P=N/A, N=60, Recruiting, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial completion, Surgery: 15-Degree Tilt, Head Up, Feet Down Body Position for Sinus Surgery Patients (clinicaltrials.gov) - Aug 27, 2013
P=N/A, N=64, Completed, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- ||||| Dupixent (dupilumab) / Sanofi, Regeneron
New P2 trial: An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis (clinicaltrials.gov) - Aug 8, 2013
P2, N=56, Recruiting, Sponsor: Sanofi
- | New P3 trial, Surgery: Safety and Performance of the Steroid-Releasing S8 Sinus Implant (clinicaltrials.gov) - Jul 8, 2013
P3, N=5, Completed, Sponsor: Intersect ENT
- Trial initiation date: VDinCRS: Vitamin D Supplementation in Chronic Rhinosinusitis With Nasal Polyps (clinicaltrials.gov) - May 19, 2013
P=N/A, N=30, Not yet recruiting, Sponsor: Medical University of South Carolina
Not yet recruiting --> Completed Initiation date: Oct 2010 --> Oct 2013
- Enrollment change: Non-Rhinologic Etiologies of Headaches and Facial Pain in Tertiary Care Setting (clinicaltrials.gov) - May 12, 2013
P=N/A, N=20, Completed, Sponsor: Penn State University
Initiation date: Oct 2010 --> Oct 2013 N=35 --> 20
- Trial completion: Non-Rhinologic Etiologies of Headaches and Facial Pain in Tertiary Care Setting (clinicaltrials.gov) - May 12, 2013
P=N/A, N=20, Completed, Sponsor: Penn State University
N=35 --> 20 Recruiting --> Completed
- Trial initiation date: Sinonasal Gas Exchange Dynamics (clinicaltrials.gov) - Apr 28, 2013
P=N/A, N=45, Recruiting, Sponsor: Louisiana State University Health Sciences Center Shreveport
Recruiting --> Completed Initiation date: Dec 2012 --> Aug 2013
- Enrollment change, Surgery: Surgery Checklist and Process Improvement Surrounding Endoscopic Sinus Surgery (clinicaltrials.gov) - Apr 22, 2013
P=N/A, N=100, Completed, Sponsor: Oregon Health and Science University
Initiation date: Dec 2012 --> Aug 2013 N=200 --> 100
- Enrollment change, Surgery: Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study (clinicaltrials.gov) - Apr 22, 2013
P=N/A, N=186, Completed, Sponsor: Oregon Health and Science University
N=200 --> 100 N=234 --> 186
- Trial completion, Surgery: Surgery Checklist and Process Improvement Surrounding Endoscopic Sinus Surgery (clinicaltrials.gov) - Apr 22, 2013
P=N/A, N=100, Completed, Sponsor: Oregon Health and Science University
N=234 --> 186 Recruiting --> Completed
- Trial completion, Surgery: Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study (clinicaltrials.gov) - Apr 22, 2013
P=N/A, N=186, Completed, Sponsor: Oregon Health and Science University
Recruiting --> Completed Active, not recruiting --> Completed
- gentamicin sulfate / Generic mfg.
Enrollment change: Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children (clinicaltrials.gov) - Apr 21, 2013
P=N/A, N=40, Completed, Sponsor: Julie Wei, MD
Active, not recruiting --> Completed N=50 --> 40
- gentamicin sulfate / Generic mfg.
Trial completion: Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children (clinicaltrials.gov) - Apr 21, 2013
P=N/A, N=40, Completed, Sponsor: Julie Wei, MD
N=50 --> 40 Active, not recruiting --> Completed
- | doxycycline / Generic mfg., azithromycin / Generic mfg.
New P4 trial: Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis (clinicaltrials.gov) - Apr 3, 2013
P4, N=100, Recruiting, Sponsor: University of North Carolina, Chapel Hill
- | budesonide inhalation suspension / Generic mfg.
New P2 trial, Surgery: Trial of Directed High-dose Nasal Steroids on Residual Smell Loss in Sinus Patients After Sinus Surgery (clinicaltrials.gov) - Mar 18, 2013
P2, N=70, Recruiting, Sponsor: University of North Carolina, Chapel Hill
- || Enrollment closed: Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up (clinicaltrials.gov) - Feb 11, 2013
P=N/A, N=120, Active, not recruiting, Sponsor: Entellus Medical, Inc.
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||||| Trial initiation date: beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study (clinicaltrials.gov) - Feb 4, 2013
P3, N=164, Active, not recruiting, Sponsor: Chiesi Farmaceutici S.p.A.
Recruiting --> Active, not recruiting Initiation date: Oct 2011 --> Jan 2013
- ||| Acetavance (acetaminophen) / Mallinckrodt
Enrollment open, Surgery: IVAPAP: Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery (clinicaltrials.gov) - Jan 17, 2013
P=N/A, N=60, Recruiting, Sponsor: The University of Texas Health Science Center, Houston
Initiation date: Oct 2011 --> Jan 2013 Not yet recruiting --> Recruiting
- simvastatin / Generic mfg.
New P2 trial: Efficacy Study of SIMVASTATIN to Treat Chronic Rhinosinusitis After Failure of Optimal Treatment (clinicaltrials.gov) - Jan 16, 2013
P2, N=20, Recruiting, Sponsor: Centre hospitalier de l'Universit
- Enrollment closed: Reversal of Tobacco-Related Sinusitis (clinicaltrials.gov) - Jan 15, 2013
P=N/A, N=150, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial termination: Surgical Reduction of the Inferior Turbinates for Nasal Obstruction (clinicaltrials.gov) - Jan 10, 2013
P4, N=30, Terminated, Sponsor: ArthroCare Corporation
Recruiting --> Active, not recruiting Completed --> Terminated
- | Pulmozyme (dornase alfa) / Roche
Trial initiation date: Pulmozyme in Cystic Fibrosis With Sinusitis (clinicaltrials.gov) - Nov 28, 2012
P3, N=12, Not yet recruiting, Sponsor: Penn State University
Completed --> Terminated Initiation date: Jul 2010 --> Jul 2013
- |||||||||| mometasone furoate nasal spray / Generic mfg.
New P3 trial, Surgery: Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps (clinicaltrials.gov) - Nov 22, 2012
P3, N=100, Active, not recruiting, Sponsor: Intersect ENT
- | Trial termination, HEOR, Surgery: CHEC: Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis (clinicaltrials.gov) - Nov 12, 2012
P4, N=200, Terminated, Sponsor: Johnson & Johnson Medical Companies
Initiation date: Jul 2010 --> Jul 2013 Recruiting --> Terminated
- Trial completion: FISHNET: Medicated Punctured-Glove-Finger Spacer Study (clinicaltrials.gov) - Oct 25, 2012
P4, N=50, Completed, Sponsor: St. Paul's Hospital, Canada
Recruiting --> Terminated Not yet recruiting --> Completed
- ||| Clinical: Comparison of Balloon Sinuplasty In-Office Versus Medical Management for Recurrent Acute Sinusitis Patients (CABERNET) (clinicaltrials.gov) - Oct 24, 2012
P=N/A, N=400, Recruiting, Sponsor: Acclarent
- epinephrine / Generic mfg.
New P4 trial, Surgery: Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery (clinicaltrials.gov) - Oct 11, 2012
P4, N=45, Recruiting, Sponsor: Marc Tewfik
- |||||||||| New P3 trial: Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic Rhinosinusitis (clinicaltrials.gov) - Oct 11, 2012
P3, N=885, Recruiting, Sponsor: Bionorica SE
- |||||||||| New P3 trial: beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study (clinicaltrials.gov) - Sep 23, 2012
P3, N=164, Active, not recruiting, Sponsor: Chiesi Farmaceutici S.p.A.
- ||| Clinical: SNS01: Application of Ectoin® Rhinitis Nasal Spray in Patients With Acute Rhinosinusitis (clinicaltrials.gov) - Sep 11, 2012
P=N/A, N=66, Completed, Sponsor: Bitop AG
- Trial completion: IRIS-ASMA: Rinitis y Sinusitis seg (clinicaltrials.gov) - Sep 6, 2012
P=N/A, N=450, Completed, Sponsor: Fundaci
Not yet recruiting --> Completed Recruiting --> Completed
- prednisone / Generic mfg.
Enrollment open: Corticosteroid Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (clinicaltrials.gov) - Sep 5, 2012
P4, N=40, Recruiting, Sponsor: Northwestern University
Recruiting --> Completed Not yet recruiting --> Recruiting
- ||||||| Kenalog-40 (triamcinolone acetonide injection suspension) / BMS
Trial completion: DELIVER: Clinical Study of Safety and Efficacy for the Relieva Stratus With Elution of Triamcinolone Acetonide (clinicaltrials.gov) - Sep 3, 2012
P3, N=63, Completed, Sponsor: Acclarent
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- || Enrollment change: ORIOS: Balloon Sinus Dilation In Office or OR (clinicaltrials.gov) - Aug 30, 2012
P=N/A, N=72, Completed, Sponsor: Acclarent
Active, not recruiting --> Completed N=100 --> 72
- ||| Trial completion: ORIOS: Balloon Sinus Dilation In Office or OR (clinicaltrials.gov) - Aug 30, 2012
P=N/A, N=72, Completed, Sponsor: Acclarent
N=100 --> 72 Active, not recruiting --> Completed
- prednisone / Generic mfg.
New P4 trial: Corticosteroid Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) (clinicaltrials.gov) - Aug 28, 2012
P4, N=40, Recruiting, Sponsor: Northwestern University
- Enrollment change: Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum (clinicaltrials.gov) - Aug 20, 2012
P=N/A, N=18, Completed, Sponsor: ENTrigue Surgical, Inc.
Active, not recruiting --> Completed N=30 --> 18
- mometasone furoate nasal spray / Generic mfg.
Enrollment closed: STAN: Study of Asthma and Nasal Steroids (clinicaltrials.gov) - Aug 20, 2012
P4, N=380, Active, not recruiting, Sponsor: American Lung Association Asthma Clinical Research Centers
N=30 --> 18 Recruiting --> Active, not recruiting
- | Trial completion: Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum (clinicaltrials.gov) - Aug 20, 2012
P=N/A, N=18, Completed, Sponsor: ENTrigue Surgical, Inc.
Recruiting --> Active, not recruiting Terminated --> Completed