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13 Companies |
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19 Products |
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19 Products |
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12 Mechanisms of Action |
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0 Trials |
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229 News |
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- Enrollment open, Trial initiation date, Trial primary completion date: The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device (clinicaltrials.gov) - Nov 23, 2014
P4, N=66, Recruiting, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting | Initiation date: Mar 2014 --> Jun 2014 | Trial primary completion date: Aug 2014 --> May 2015
- Enrollment open, Trial primary completion date, Surgery: SYNECHIAE: Rates of Middle Meatal Synechia Formation Following Functional Endoscopic Sinus Surgery (clinicaltrials.gov) - Nov 23, 2014
P=N/A, N=96, Recruiting, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting | Initiation date: Mar 2014 --> Jun 2014 | Trial primary completion date: Aug 2014 --> May 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Apr 2015
- Enrollment closed, Trial primary completion date, Surgery: Hot Saline Irrigation Study (clinicaltrials.gov) - Nov 23, 2014
P=N/A, N=60, Active, not recruiting, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting | Trial primary completion date: Sep 2014 --> Apr 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2014 --> Mar 2015
- | New P4 trial: CESAR: Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis (clinicaltrials.gov) - Nov 20, 2014
P4, N=290, Not yet recruiting, Sponsor: Hevert-Arzneimittel GmbH & Co. KG
- Nasonex (mometasone furoate nasal spray) / Merck (MSD)
Clinical: RESOLVEII: S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps (clinicaltrials.gov) - Nov 14, 2014
P=N/A, N=0, Withheld, Sponsor: [Redacted]
- Pulmozyme (dornase alfa) / Roche
Trial completion, Enrollment change: Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis (clinicaltrials.gov) - Nov 14, 2014
P2, N=16, Completed, Sponsor: University of Vermont
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2014 --> Mar 2015 Active, not recruiting --> Completed | N=20 --> 16
- Clinical: Sinus Balloon Dilation in Pediatric Patients (clinicaltrials.gov) - Oct 30, 2014
P=N/A, N=50, Recruiting, Sponsor: Entellus Medical, Inc.
- Phase classification, Surgery: Safety and Performance of the Steroid-Releasing S8 Sinus Implant (clinicaltrials.gov) - Oct 17, 2014
P2, N=5, Completed, Sponsor: Intersect ENT
Active, not recruiting --> Completed | N=20 --> 16 Phase classification: P3 --> P2
- ||||| New P4 trial: Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal Sinus (clinicaltrials.gov) - Oct 17, 2014
P4, N=80, Recruiting, Sponsor: Intersect ENT
- Trial primary completion date: Reversal of Tobacco-Related Sinusitis (clinicaltrials.gov) - Oct 11, 2014
P=N/A, N=150, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Phase classification: P3 --> P2 Trial primary completion date: Jul 2014 --> Dec 2014
- | Trial completion, Enrollment change, Surgery: PerClot to Control Bleeding in Endoscopic Sinus Surgery (clinicaltrials.gov) - Oct 4, 2014
P=N/A, N=12, Completed, Sponsor: CryoLife Europa
Trial primary completion date: Jul 2014 --> Dec 2014 Recruiting --> Completed | N=10 --> 12
- Clinical: Primary Care Clinician Commitments to Choosing Wisely® (clinicaltrials.gov) - Sep 28, 2014
P=N/A, N=60, Enrolling by invitation, Sponsor: University of Michigan
- | Trial completion: Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium (clinicaltrials.gov) - Sep 28, 2014
P1, N=36, Completed, Sponsor: SinuSys Corporation
Recruiting --> Completed | N=10 --> 12 Active, not recruiting --> Completed
- || Trial primary completion date: ORIOS 2: Optimization and Refinement of Technique in In-Office Sinus Dilation 2 (clinicaltrials.gov) - Sep 19, 2014
P=N/A, N=203, Completed, Sponsor: Acclarent
Active, not recruiting --> Completed Trial primary completion date: Aug 2012 --> Jan 2012
- azithromycin / Generic mfg.
Enrollment closed, Trial primary completion date: Efficacy of Azithromycin Prophylaxis in Preventing Recurrent Acute Sinusitis in Children (clinicaltrials.gov) - Sep 9, 2014
P=N/A, N=40, Active, not recruiting, Sponsor: Mahidol University
Trial primary completion date: Aug 2012 --> Jan 2012 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Dec 2015
- Trial completion, Trial primary completion date: Clinical Characteristic of Recurrent Acute Rhinosinusitis in Children (clinicaltrials.gov) - Sep 9, 2014
P=N/A, N=94, Completed, Sponsor: Mahidol University
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Dec 2015 Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Apr 2014
- Surgery: PerClot to Control Bleeding in Endoscopic Sinus Surgery (clinicaltrials.gov) - Aug 21, 2014
P=N/A, N=10, Recruiting, Sponsor: CryoLife Europa
- |||| Trial primary completion date: Study Evaluating the Safety of Intranasal Administration of 400 ?g of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps (clinicaltrials.gov) - Aug 15, 2014
P3, N=700, Recruiting, Sponsor: Optinose US Inc.
Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Apr 2014 Trial primary completion date: Sep 2014 --> Dec 2014
- ||| astegolimab (RG 6149) / Amgen, Roche
Enrollment open: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps (clinicaltrials.gov) - Aug 5, 2014
P1, N=84, Recruiting, Sponsor: Amgen
Trial primary completion date: Sep 2014 --> Dec 2014 Not yet recruiting --> Recruiting
- ||||||| Trial completion: beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study (clinicaltrials.gov) - Jul 24, 2014
P3, N=166, Completed, Sponsor: Chiesi Farmaceutici S.p.A.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- fluticasone / Generic mfg.
Surgery: Comparison of Nasal Steroids After FESS in CRSwNP (clinicaltrials.gov) - Jul 18, 2014
P=N/A, N=60, Not yet recruiting, Sponsor: Yale University
- Clinical: Effect of Squeezable Bottle Nasal Irrigation Device in Children With Sinusitis (clinicaltrials.gov) - Jul 15, 2014
P=N/A, N=80, Completed, Sponsor: Thammasat University
- clarithromycin / Generic mfg.
Surgery: Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery (clinicaltrials.gov) - Jul 8, 2014
P=N/A, N=100, Recruiting, Sponsor: Zheng Liu
- ||||||| Trial completion: Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic Rhinosinusitis (clinicaltrials.gov) - Jul 8, 2014
P3, N=927, Completed, Sponsor: Bionorica SE
Active, not recruiting --> Completed Recruiting --> Completed
- mometasone furoate nasal spray / Generic mfg.
Trial completion: STAN: Study of Asthma and Nasal Steroids (clinicaltrials.gov) - Jul 3, 2014
P4, N=388, Completed, Sponsor: American Lung Association Asthma Clinical Research Centers
Recruiting --> Completed Active, not recruiting --> Completed
- ||| Dupixent (dupilumab) / Sanofi, Regeneron
Enrollment closed: An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis (clinicaltrials.gov) - Jun 27, 2014
P2, N=56, Active, not recruiting, Sponsor: Sanofi
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||| astegolimab (RG 6149) / Amgen, Roche
New P1 trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps (clinicaltrials.gov) - Jun 24, 2014
P1, N=84, Not yet recruiting, Sponsor: Amgen
- ||||||| mometasone furoate nasal spray / Generic mfg.
Trial completion, Surgery: Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps (clinicaltrials.gov) - Jun 19, 2014
P3, N=100, Completed, Sponsor: Intersect ENT
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Trial completion date, HEOR: Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life (clinicaltrials.gov) - May 28, 2014
P4, N=100, Active, not recruiting, Sponsor: University of Chicago
Active, not recruiting --> Completed Trial completion date: Dec 2009 --> Dec 2014
- | Trial completion date: Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up (clinicaltrials.gov) - May 21, 2014
P=N/A, N=151, Completed, Sponsor: Entellus Medical, Inc.
Trial completion date: Dec 2009 --> Dec 2014 Trial completion date: Dec 2013 --> May 2014
- || Trial primary completion date: Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up (clinicaltrials.gov) - May 21, 2014
P=N/A, N=81, Completed, Sponsor: Entellus Medical, Inc.
Trial completion date: Dec 2013 --> May 2014 Trial primary completion date: Dec 2014 --> Dec 2013
- || Enrollment change: Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up (clinicaltrials.gov) - May 21, 2014
P=N/A, N=81, Completed, Sponsor: Entellus Medical, Inc.
Trial primary completion date: Dec 2014 --> Dec 2013 N=120 --> 81
- Trial primary completion date: Xylitol Versus Saline in Chronic Sinusitis (clinicaltrials.gov) - May 19, 2014
P=N/A, N=56, Recruiting, Sponsor: University of Iowa
N=120 --> 81 Trial primary completion date: Sep 2012 --> Sep 2012
- Trial completion date: Xylitol Versus Saline in Chronic Sinusitis (clinicaltrials.gov) - May 19, 2014
P=N/A, N=56, Recruiting, Sponsor: University of Iowa
Trial primary completion date: Sep 2012 --> Sep 2012 Trial completion date: Sep 2012 --> Sep 2012
- ||| Trial completion: Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up (clinicaltrials.gov) - May 19, 2014
P=N/A, N=81, Completed, Sponsor: Entellus Medical, Inc.
Trial completion date: Sep 2012 --> Sep 2012 Active, not recruiting --> Completed
- |||| Trial completion, Surgery: Saline Irrigation After Surgery in Patients With Chronic Sinusitis (clinicaltrials.gov) - Apr 21, 2014
P4, N=86, Completed, Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- || mitomycin / Generic mfg.
New P3 trial, HEOR, Surgery: Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis (clinicaltrials.gov) - Apr 6, 2014
P3, N=388, Not yet recruiting, Sponsor: Mahidol University
- Trial completion: ORIOS 2: Optimization and Refinement of Technique in In-Office Sinus Dilation 2 (clinicaltrials.gov) - Mar 18, 2014
P=N/A, N=203, Completed, Sponsor: Acclarent
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Budesonide Application Via Mucosal Atomization Device as a Treatment for Chronic Rhinosinusitis When Utilized as a Topical Nasal Steroid Spray (clinicaltrials.gov) - Mar 6, 2014
P1/2, N=20, Completed, Sponsor: St. Paul's Hospital, Canada
Active, not recruiting --> Completed N=30 --> 20
- Trial completion: Budesonide Application Via Mucosal Atomization Device as a Treatment for Chronic Rhinosinusitis When Utilized as a Topical Nasal Steroid Spray (clinicaltrials.gov) - Mar 6, 2014
P1/2, N=20, Completed, Sponsor: St. Paul's Hospital, Canada
N=30 --> 20 Recruiting --> Completed
- Enrollment closed: Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium (clinicaltrials.gov) - Mar 5, 2014
P1, N=40, Active, not recruiting, Sponsor: SinuSys Corporation
Recruiting --> Completed Recruiting --> Active, not recruiting
- | New P4 trial: The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device (clinicaltrials.gov) - Mar 4, 2014
P4, N=66, Not yet recruiting, Sponsor: St. Paul's Hospital, Canada
- dexmedetomidine / Generic mfg.
Surgery: Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery (clinicaltrials.gov) - Mar 3, 2014
P4, N=66, Completed, Sponsor: Yonsei University
Recruiting --> Active, not recruiting Recruiting --> Completed
- Surgery: SYNECHIAE: Rates of Middle Meatal Synechia Formation Following Functional Endoscopic Sinus Surgery (clinicaltrials.gov) - Mar 2, 2014
P=N/A, N=96, Not yet recruiting, Sponsor: St. Paul's Hospital, Canada
- ||||| Enrollment closed: beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study (clinicaltrials.gov) - Feb 13, 2014
P3, N=164, Active, not recruiting, Sponsor: Chiesi Farmaceutici S.p.A.
Recruiting --> Completed Recruiting --> Active, not recruiting
- Enrollment open: Sinonasal Gas Exchange Dynamics (clinicaltrials.gov) - Jan 9, 2014
P=N/A, N=45, Recruiting, Sponsor: Louisiana State University Health Sciences Center Shreveport
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Enrollment change, Surgery: Manuka Honey Irrigation After Sinus Surgery (clinicaltrials.gov) - Dec 1, 2013
P1/2, N=78, Completed, Sponsor: St. Paul's Hospital, Canada
Not yet recruiting --> Recruiting N=100 --> 78
- Trial completion, Surgery: Manuka Honey Irrigation After Sinus Surgery (clinicaltrials.gov) - Dec 1, 2013
P1/2, N=78, Completed, Sponsor: St. Paul's Hospital, Canada
N=100 --> 78 Recruiting --> Completed
- || amoxycillin/clavulanate / Generic mfg.
Trial completion: Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis (clinicaltrials.gov) - Nov 26, 2013
P3, N=27, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed Active, not recruiting --> Completed
- ||||| mometasone furoate nasal spray / Generic mfg.
Enrollment closed, Surgery: Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps (clinicaltrials.gov) - Nov 7, 2013
P3, N=100, Active, not recruiting, Sponsor: Intersect ENT
Active, not recruiting --> Completed Recruiting --> Active, not recruiting