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93 Companies |
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118 Products |
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118 Products |
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88 Mechanisms of Action |
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3 Trials |
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1622 News |
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- | Amitiza (lubiprostone) / Takeda, Mallinckrodt
Enrollment change: Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) - Feb 23, 2012
P4, N=19, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
N=24 --> 19
- | Amitiza (lubiprostone) / Takeda, Mallinckrodt
Trial completion: Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) - Feb 23, 2012
P4, N=19, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
N=24 --> 19 Recruiting --> Completed
- HEOR: Pakistan Flocculent Health Outcome Study (clinicaltrials.gov) - Feb 20, 2012
P=N/A, N=8949, Completed, Sponsor: Centers for Disease Control and Prevention
- | Trial completion: Naloxone SR Capsules in Patients With Opioid Induced Constipation (clinicaltrials.gov) - Feb 15, 2012
P2, N=40, Completed, Sponsor: S.L.A. Pharma AG
Recruiting --> Completed Active, not recruiting --> Completed
- ||||| Trial initiation date: HMX3501: Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain (clinicaltrials.gov) - Feb 13, 2012
P2/3, N=600, Completed, Sponsor: Mundipharma Research GmbH & Co KG
Active, not recruiting --> Completed Initiation date: Oct 2009 --> Jan 2010
- ||||||| Trial completion: HMX3501: Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain (clinicaltrials.gov) - Feb 13, 2012
P2/3, N=600, Completed, Sponsor: Mundipharma Research GmbH & Co KG
Initiation date: Oct 2009 --> Jan 2010 Recruiting --> Completed
- Trial completion: Decreasing the Incidence of Post-Operative Nausea and Vomiting (PONV) in Bariatric Patients (clinicaltrials.gov) - Feb 13, 2012
P=N/A, N=125, Completed, Sponsor: University of Pennsylvania
Recruiting --> Completed Recruiting --> Completed
- | Movantik (naloxegol) / AstraZeneca, RedHill, Kyowa Kirin
New P1 trial: Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118 (clinicaltrials.gov) - Feb 13, 2012
P1, N=22, Completed, Sponsor: AstraZeneca
- | Movantik (naloxegol) / AstraZeneca, RedHill, Kyowa Kirin
New P1 trial: Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118 (clinicaltrials.gov) - Feb 13, 2012
P1, N=46, Completed, Sponsor: AstraZeneca
- || azithromycin / Generic mfg.
New P3 trial: Concisus2012: Trial Of Azithromycin In Campylobacter Concisus Patients With Diarrhea (clinicaltrials.gov) - Feb 8, 2012
P3, N=100, Recruiting, Sponsor: University of Aarhus
- dronabinol oral / Generic mfg.
Trial initiation date: Delta-pain: Efficacy Study of Δ9-THC to Treat Chronic Abdominal Pain (clinicaltrials.gov) - Feb 6, 2012
P2, N=24, Completed, Sponsor: Radboud University
Recruiting --> Completed Initiation date: May 2011 --> Oct 2011
- ||||| Enrollment change: Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC). (clinicaltrials.gov) - Feb 5, 2012
P3, N=117, Completed, Sponsor: Sanofi
Initiation date: May 2011 --> Oct 2011 N=96 --> 117
- Trial completion: The Effects of a Ficus Carica on Improvement in Bowl Movements in Female Volunteer With Functional Constipation (clinicaltrials.gov) - Feb 5, 2012
P=N/A, N=40, Completed, Sponsor: Chonbuk National University Hospital
N=96 --> 117 Enrolling by invitation --> Completed
- ||||||| Trial completion: Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC). (clinicaltrials.gov) - Feb 5, 2012
P3, N=117, Completed, Sponsor: Sanofi
Enrolling by invitation --> Completed Recruiting --> Completed
- ||||| relenopride (YKP-GI) / SK Bio
New P2 trial: A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation (clinicaltrials.gov) - Jan 30, 2012
P2, N=100, Active, not recruiting, Sponsor: SK Life Science
- | Trial completion: PND: L Reuteri for the Prevention of Nosocomial Diarrhea (clinicaltrials.gov) - Jan 26, 2012
P3, N=106, Completed, Sponsor: Medical University of Warsaw
Recruiting --> Completed Recruiting --> Completed
- ||||||| Linzess (linaclotide) / Astellas, Ironwood Pharma, AbbVie
Trial completion: An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation (clinicaltrials.gov) - Jan 26, 2012
P3, N=1557, Completed, Sponsor: Forest Laboratories
Recruiting --> Completed Active, not recruiting --> Completed
- esomeprazole / Generic mfg.
Trial termination: Nexium Study To Suppress Nausea During Chemotherapy (clinicaltrials.gov) - Jan 23, 2012
P3, N=43, Terminated, Sponsor: Baylor Breast Care Center
Active, not recruiting --> Completed Active, not recruiting --> Terminated; Accrual was not optimized
- Enrollment change: Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children (clinicaltrials.gov) - Jan 22, 2012
P1, N=845, Completed, Sponsor: Haramaya Unversity
Active, not recruiting --> Terminated; Accrual was not optimized N=576 --> 845
- Trial completion: Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children (clinicaltrials.gov) - Jan 22, 2012
P1, N=845, Completed, Sponsor: Haramaya Unversity
N=576 --> 845 Recruiting --> Completed
- | Trial termination: Probiotics and the Prevention of Traveler's Diarrhea (clinicaltrials.gov) - Jan 17, 2012
P4, N=420, Terminated, Sponsor: Lallemand SAS
Recruiting --> Completed Recruiting --> Terminated; because of low rate recruitment and the inability to reach the target expected
- olanzapine / Generic mfg., haloperidol / Generic mfg.
Trial termination, Metastases: Study Comparing Olanzapine With Haloperidol for the Relief of Nausea and Vomiting in Patients With Advanced Cancer (clinicaltrials.gov) - Jan 17, 2012
P3, N=80, Terminated, Sponsor: AHS Cancer Control Alberta
Recruiting --> Terminated; because of low rate recruitment and the inability to reach the target expected Suspended --> Terminated; Study suspended due to low enrollment
- | Trial completion: Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT) (clinicaltrials.gov) - Jan 17, 2012
P=N/A, N=30, Completed, Sponsor: Mayo Clinic
Suspended --> Terminated; Study suspended due to low enrollment Active, not recruiting --> Completed
- ||||||| esomeprazole / Generic mfg.
Trial completion: NEXT2: Efficacy of Esomeprazole in Patients With Frequent Heartburn (clinicaltrials.gov) - Jan 16, 2012
P3, N=341, Completed, Sponsor: AstraZeneca
Active, not recruiting --> Completed Recruiting --> Completed
- ||||||| esomeprazole / Generic mfg.
Trial completion: NEXT1: Efficacy of Esomeprazole in Patients With Frequent Heartburn (clinicaltrials.gov) - Jan 16, 2012
P3, N=340, Completed, Sponsor: AstraZeneca
Recruiting --> Completed Recruiting --> Completed
- | Ganaton (itopride) / Abbott
New P2 trial: Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective (clinicaltrials.gov) - Jan 15, 2012
P2, N=115, Completed, Sponsor: Shanghai Jiao Tong University School of Medicine
- ||||| Barhemsys (intravenous amisulpride) / Eagle Pharma
New P2 trial: Phase II Dose-ranging Study of APD421 in PONV (clinicaltrials.gov) - Jan 12, 2012
P2, N=215, Completed, Sponsor: Acacia Pharma Ltd
- ||| ondansetron intravenous / Generic mfg., moxifloxacin intravenous / Generic mfg.
Trial completion: To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects (clinicaltrials.gov) - Jan 12, 2012
P1, N=58, Completed, Sponsor: GlaxoSmithKline
Recruiting --> Completed Recruiting --> Completed
- ||| Barhemsys (intravenous amisulpride) / Eagle Pharma
Enrollment change: Phase II Proof-of-concept Study of APD421 (clinicaltrials.gov) - Jan 11, 2012
P2, N=51, Completed, Sponsor: Acacia Pharma Ltd
Recruiting --> Completed N=40 --> 51
- New P2 trial: Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial) (clinicaltrials.gov) - Jan 10, 2012
P2, N=50, Recruiting, Sponsor: Massachusetts General Hospital
- dexamethasone / Generic mfg., ketamine / Generic mfg.
Trial initiation date: Efficacy of Dexamethasone for Prevent Vomiting in Leukemic Children Who Receive Intrathecal Chemotherapy (clinicaltrials.gov) - Jan 9, 2012
P4, N=32, Completed, Sponsor: CHANCHAI TRAIVAREE
N=40 --> 51 Initiation date: Apr 2010 --> Apr 2011
- dexamethasone / Generic mfg., ketamine / Generic mfg.
Trial completion: Efficacy of Dexamethasone for Prevent Vomiting in Leukemic Children Who Receive Intrathecal Chemotherapy (clinicaltrials.gov) - Jan 9, 2012
P4, N=32, Completed, Sponsor: CHANCHAI TRAIVAREE
Initiation date: Apr 2010 --> Apr 2011 Recruiting --> Completed
- ||||| ondansetron intravenous / Generic mfg.
New P2 trial: A Study of Vestipitant (GW597599) in the Treatment of Breakthrough Postoperative Nausea and Vomiting (PONV) (clinicaltrials.gov) - Jan 8, 2012
P2, N=131, Completed, Sponsor: Accenture
- ||||| New P2 trial: Exploratory Clinical Study to Evaluate the Optimal Dosage of Mosapride and Probiotics in Irritable Bowel Syndrome Without Predominant Diarrhea (clinicaltrials.gov) - Jan 5, 2012
P2, N=280, Completed, Sponsor: Hanmi Pharmaceutical Company Limited
- megestrol / Generic mfg., mirtazapine / Generic mfg.
New P2 trial: Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite (clinicaltrials.gov) - Dec 27, 2011
P2, N=0, Withdrawn, Sponsor: Washington University School of Medicine
- | montelukast / Generic mfg.
Trial completion: Montelukast in the Treatment of Duodenal Eosinophilia (clinicaltrials.gov) - Dec 27, 2011
P=N/A, N=24, Completed, Sponsor: Children's Mercy Hospital Kansas City
Recruiting --> Completed Recruiting --> Completed
- |||||||||| Varubi (rolapitant oral) / TerSera Therap, GSK
New P3 trial: Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy (clinicaltrials.gov) - Dec 26, 2011
P3, N=1369, Completed, Sponsor: Tesaro, Inc.
- |||||||||| Varubi (rolapitant oral) / TerSera Therap, GSK
New P3 trial, CINV: Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy (clinicaltrials.gov) - Dec 26, 2011
P3, N=555, Completed, Sponsor: Tesaro, Inc.
- |||||||||| Varubi (rolapitant oral) / TerSera Therap, GSK
New P3 trial, CINV: Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy (clinicaltrials.gov) - Dec 22, 2011
P3, N=530, Recruiting, Sponsor: Tesaro, Inc.
- ||| aprepitant oral / Generic mfg.
Trial completion: Re-examination Study of EMEND (Aprepitant) (MK-0869-184) (clinicaltrials.gov) - Dec 21, 2011
P=N/A, N=3546, Completed, Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed Active, not recruiting --> Completed
- |||| Trial completion: Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients (clinicaltrials.gov) - Dec 21, 2011
P1/2, N=52, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial initiation date: Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain (clinicaltrials.gov) - Dec 20, 2011
P=N/A, N=81, Active, not recruiting, Sponsor: Medical College of Wisconsin
Active, not recruiting --> Completed Initiation date: Apr 2006 --> Dec 2006
- ||||||| Movicol (polyethylene glycol/sodium bicarbonate/sodium chloride/potassium chloride) / Mochida, Eisai, Norgine
Trial completion: Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515) (clinicaltrials.gov) - Dec 20, 2011
P3, N=154, Completed, Sponsor: Merck Sharp & Dohme Corp.
Initiation date: Apr 2006 --> Dec 2006 Recruiting --> Completed
- Decadron (dexamethasone) / Merck (MSD)
Trial completion: Aprepitant in Preventing Nausea and Vomiting in Patients Who Are Undergoing a Stem Cell Transplant (clinicaltrials.gov) - Dec 19, 2011
P=N/A, N=40, Completed, Sponsor: OHSU Knight Cancer Institute
Recruiting --> Completed Active, not recruiting --> Completed
- | New P4 trial: Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood (clinicaltrials.gov) - Dec 18, 2011
P4, N=90, Completed, Sponsor: Medical University of Warsaw
- Trial initiation date: A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation (clinicaltrials.gov) - Dec 14, 2011
P2, N=97, Completed, Sponsor: Hong Kong Baptist University
Active, not recruiting --> Completed Initiation date: Mar 2006 --> Oct 2006
- ||| ifosfamide / Generic mfg., doxorubicin hydrochloride / Generic mfg.
Trial completion: Palonosetron in Sarcoma Patients Receiving Chemotherapy With Adriamycin and Ifosfamide (AI) (clinicaltrials.gov) - Dec 14, 2011
P=N/A, N=51, Completed, Sponsor: M.D. Anderson Cancer Center
Initiation date: Mar 2006 --> Oct 2006 Active, not recruiting --> Completed
- Enrollment change: Motivation to Exercise in People With Anorexia Nervosa (clinicaltrials.gov) - Dec 13, 2011
P=N/A, N=60, Completed, Sponsor: New York State Psychiatric Institute
Active, not recruiting --> Completed N=16 --> 60
- Enrollment change: Hormone Release and Stomach Disturbances in People With Binge Eating Disorder (clinicaltrials.gov) - Dec 13, 2011
P=N/A, N=24, Completed, Sponsor: New York State Psychiatric Institute
N=16 --> 60 N=32 --> 24
- Trial completion: Motivation to Exercise in People With Anorexia Nervosa (clinicaltrials.gov) - Dec 13, 2011
P=N/A, N=60, Completed, Sponsor: New York State Psychiatric Institute
N=32 --> 24 Recruiting --> Completed