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93 Companies |
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118 Products |
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118 Products |
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88 Mechanisms of Action |
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3 Trials |
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1622 News |
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- Enrollment open: Alternative Approaches for Nausea Control (clinicaltrials.gov) - Apr 17, 2013
P2, N=216, Recruiting, Sponsor: University of Rochester
Not yet recruiting --> Recruiting
- ||||| alfuzosin hydrochloride / Generic mfg.
New P2 trial: Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions (clinicaltrials.gov) - Apr 16, 2013
P2, N=72, Recruiting, Sponsor: Mayo Clinic
- |||| alfuzosin hydrochloride / Generic mfg.
Enrollment open: Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions (clinicaltrials.gov) - Apr 16, 2013
P2, N=72, Recruiting, Sponsor: Mayo Clinic
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- fosaprepitant / Generic mfg.
Trial termination, Metastases: Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy (clinicaltrials.gov) - Apr 16, 2013
P2, N=6, Terminated, Sponsor: University of Washington
Not yet recruiting --> Recruiting Completed --> Terminated; Study stopped due to lack of efficacy in first 6 patients
- fosaprepitant / Generic mfg.
Enrollment change, Metastases: Fosaprepitant Dimeglumine, Palonosetron Hydrochloride, and Dexamethasone in Preventing Nausea and Vomiting Caused by Cisplatin in Patients With Stage III or Stage IV Head and Neck Cancer Undergoing Chemotherapy and Radiation Therapy (clinicaltrials.gov) - Apr 16, 2013
P2, N=6, Terminated, Sponsor: University of Washington
Completed --> Terminated; Study stopped due to lack of efficacy in first 6 patients N=45 --> 6
- |||| Symproic (naldemedine) / Shionogi, Collegium Pharma
Trial completion: A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy (clinicaltrials.gov) - Apr 15, 2013
P2, N=244, Completed, Sponsor: Shionogi
N=45 --> 6 Active, not recruiting --> Completed
- ||| elobixibat (A3309) / Albireo, Ajinomoto, Ferring
New P3 trial: Efficacy and Safety Trial of Elobixibat in Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) - Apr 14, 2013
P3, N=840, Suspended, Sponsor: Ferring Pharmaceuticals
- |||||| Enrollment open: Effect of Probiotic Formula on Reducing the Risk for Antibiotic-associated Diarrhoea (clinicaltrials.gov) - Apr 9, 2013
P2/3, N=400, Recruiting, Sponsor: Danisco
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ||| elobixibat (A3309) / Albireo, Ajinomoto, Ferring
New P3 trial: 26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) - Apr 7, 2013
P3, N=840, Suspended, Sponsor: Ferring Pharmaceuticals
- Emestop (ramosetron hydrochloride) / Samyang Group
Surgery: Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery (clinicaltrials.gov) - Apr 4, 2013
P=N/A, N=196, Completed, Sponsor: Yonsei University
- | Trial completion: Micronutrient Sprinkles in a Daycare Center (clinicaltrials.gov) - Apr 4, 2013
P3, N=143, Completed, Sponsor: Emory University
Not yet recruiting --> Recruiting Recruiting --> Completed
- ||||||| palonosetron intravenous / Generic mfg.
Trial completion, CINV: Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients (clinicaltrials.gov) - Apr 4, 2013
P3, N=494, Completed, Sponsor: Helsinn Healthcare SA
Recruiting --> Completed Active, not recruiting --> Completed
- |||| Trial completion: Exploratory Clinical Study to Evaluate the Optimal Dosage of Mosapride and Probiotics in Irritable Bowel Syndrome Without Predominant Diarrhea (clinicaltrials.gov) - Apr 3, 2013
P2, N=280, Completed, Sponsor: Hanmi Pharmaceutical Company Limited
Active, not recruiting --> Completed Recruiting --> Completed
- |||||||||| New P2/3 trial: Influence of Protein Supplements on Serum Insulin-like Growth Factor-I Levels in Women With Anorexia Nervosa (clinicaltrials.gov) - Apr 2, 2013
P2/3, N=62, Completed, Sponsor: University Hospital, Geneva
- New P1/2 trial: PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera (clinicaltrials.gov) - Apr 2, 2013
P1/2, N=26, Completed, Sponsor: PATH
- | miglustat / Generic mfg.
New P1 trial: Two Period / Two Treatment Cross-over to Assess the Effect of Florastor (clinicaltrials.gov) - Mar 31, 2013
P1, N=42, Active, not recruiting, Sponsor: Actelion
- | New P2 trial: Modified ORS Solution for Severely Malnourished Children (clinicaltrials.gov) - Mar 28, 2013
P2, N=189, Completed, Sponsor: International Centre for Diarrhoeal Disease Research, Bangladesh
- megestrol / Generic mfg.
Trial termination: Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy (clinicaltrials.gov) - Mar 28, 2013
P2, N=1, Terminated, Sponsor: Mayo Clinic
Recruiting --> Completed Active, not recruiting --> Terminated; The study closed due to slow accrual.
- megestrol / Generic mfg.
Enrollment change: Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy (clinicaltrials.gov) - Mar 28, 2013
P2, N=1, Terminated, Sponsor: Mayo Clinic
Active, not recruiting --> Terminated; The study closed due to slow accrual. N=88 --> 1
- Enrollment change: Treatment for Young Adults With Anorexia Nervosa (clinicaltrials.gov) - Mar 25, 2013
P1/2, N=30, Recruiting, Sponsor: Temple University
N=88 --> 1 N=90 --> 30
- Enrollment change: Comparing the Effectiveness of Three Types of Therapy for the Treatment of Anorexia Nervosa in Adolescents (clinicaltrials.gov) - Mar 25, 2013
P2, N=121, Active, not recruiting, Sponsor: University of Chicago
N=90 --> 30 N=180 --> 121
- | Enrollment open: Acupuncture for Patients With Function Dyspepsia (clinicaltrials.gov) - Mar 25, 2013
P3, N=200, Recruiting, Sponsor: Chengdu University of Traditional Chinese Medicine
N=180 --> 121 Not yet recruiting --> Recruiting
- Trial termination: Study Comparing Early Laparoscopy With Active Observation in Acute Non-specific Abdominal Pain (clinicaltrials.gov) - Mar 23, 2013
P4, N=17, Terminated, Sponsor: Mid Western Regional Hospital, Ireland
Not yet recruiting --> Recruiting Recruiting --> Terminated; Difficulties with recruitment
- Enrollment change: Study Comparing Early Laparoscopy With Active Observation in Acute Non-specific Abdominal Pain (clinicaltrials.gov) - Mar 23, 2013
P4, N=17, Terminated, Sponsor: Mid Western Regional Hospital, Ireland
Recruiting --> Terminated; Difficulties with recruitment N=400 --> 17
- Trial termination: Description and Evaluation of Eating Disorders in Elite Athletes (TCA SHN) (clinicaltrials.gov) - Mar 21, 2013
P=N/A, N=386, Terminated, Sponsor: Nantes University Hospital
N=400 --> 17 Completed --> Terminated
- ||||| New P4 trial: A Study to Demonstrate the Efficacy and Safety of Motilitone® (clinicaltrials.gov) - Mar 21, 2013
P4, N=387, Recruiting, Sponsor: Dong-A Pharmaceutical Co., Ltd.
- Surgery: NeoNec: Neonates With Very Low Birth Weight and Surgery Therapy of Acute Abdomen (clinicaltrials.gov) - Mar 20, 2013
P=N/A, N=89, Completed, Sponsor: Charite University, Berlin, Germany
- | relamorelin (RM-131) / AbbVie
Enrollment open, P2 data: Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation (clinicaltrials.gov) - Mar 20, 2013
P2, N=48, Recruiting, Sponsor: Rhythm Pharmaceuticals, Inc.
Completed --> Terminated Not yet recruiting --> Recruiting
- | dexamethasone injection / Generic mfg.
New P4 trial: Dexamethasone for Post-cesarean Delivery Pain (clinicaltrials.gov) - Mar 13, 2013
P4, N=104, Recruiting, Sponsor: Duke University
- ||||| New P4 trial: A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation (clinicaltrials.gov) - Mar 11, 2013
P4, N=97, Completed, Sponsor: Bayer
- ||| New P3 trial: IQP-PO-101 for the Regulation of Bowel Movement Frequency (clinicaltrials.gov) - Mar 10, 2013
P3, N=50, Completed, Sponsor: InQpharm Group
- Enrollment open: Stress and Eating Study (clinicaltrials.gov) - Mar 6, 2013
P=N/A, N=154, Enrolling by invitation, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Not yet recruiting --> Enrolling by invitation
- | Trial completion: Safety and Efficacy of IQP-LH-101 in Postprandial Heartburn (clinicaltrials.gov) - Mar 6, 2013
P4, N=41, Completed, Sponsor: InQpharm Group
Not yet recruiting --> Enrolling by invitation Recruiting --> Completed
- | Emestop (ramosetron hydrochloride) / Samyang Group
New P2 trial: Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting (clinicaltrials.gov) - Mar 5, 2013
P2, N=96, Recruiting, Sponsor: Seoul National University Hospital
- ||||| Enrollment closed: B. Lactis HN019 for Functional Constipation (clinicaltrials.gov) - Mar 5, 2013
P3, N=228, Active, not recruiting, Sponsor: Fonterra Research Centre
Recruiting --> Completed Recruiting --> Active, not recruiting
- | Enrollment closed: A Study of Rabeprazole for Prevention of Non Steroidal Anti-inflammatory Drug -Associated Gastroduodenal Injury (clinicaltrials.gov) - Mar 3, 2013
P3, N=112, Active, not recruiting, Sponsor: Chinese University of Hong Kong
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- ondansetron / Generic mfg., tropisetron / Generic mfg.
Trial completion: Acupressure and Acustimulation Wrist Bands for the Prevention of Nausea and Vomiting Caused by Chemotherapy (clinicaltrials.gov) - Mar 3, 2013
P2, N=700, Completed, Sponsor: Gary Morrow
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ondansetron / Generic mfg.
Trial completion: Patient Education in Preventing Nausea and Vomiting in Cancer Patients Receiving Chemotherapy (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=0, Completed, Sponsor: University of Rochester
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||||| esomeprazole / Generic mfg.
Enrollment change: NEXT2: Efficacy of Esomeprazole in Patients With Frequent Heartburn (clinicaltrials.gov) - Feb 28, 2013
P3, N=341, Completed, Sponsor: AstraZeneca
Active, not recruiting --> Completed N=526 --> 341
- aprepitant oral / Generic mfg.
Enrollment open: A Study to Evaluate Aprepitant for the Prevention of Post-Operative Nausea and Vomiting in Children (MK-0869-219) (clinicaltrials.gov) - Feb 28, 2013
P2b, N=260, Recruiting, Sponsor: Merck Sharp & Dohme Corp.
N=526 --> 341 Not yet recruiting --> Recruiting
- Relistor (methylnaltrexone bromide) / Ono Pharma, Bausch Health
Enrollment change: Methylnaltrexone Use for Opioid-induced Postoperative Constipation (clinicaltrials.gov) - Feb 27, 2013
P4, N=60, Recruiting, Sponsor: Shriners Hospitals for Children
Not yet recruiting --> Recruiting N=100 --> 60
- Trial termination: Randomized Trial of Mosapride Versus Placebo in the Treatment of Constipation-Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Feb 26, 2013
P3, N=41, Terminated, Sponsor: American University of Beirut Medical Center
N=100 --> 60 Completed --> Terminated; Poor recruitment, high drop out rate
- Enrollment change: Randomized Trial of Mosapride Versus Placebo in the Treatment of Constipation-Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Feb 26, 2013
P3, N=41, Terminated, Sponsor: American University of Beirut Medical Center
Completed --> Terminated; Poor recruitment, high drop out rate N=130 --> 41
- ||||| Enrollment change: Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment. (clinicaltrials.gov) - Feb 25, 2013
P3, N=96, Completed, Sponsor: Sanofi
N=130 --> 41 N=136 --> 96
- | pregabalin / Generic mfg.
Enrollment change: Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Feb 24, 2013
P4, N=18, Completed, Sponsor: Mayo Clinic
N=136 --> 96 N=40 --> 18
- | pregabalin / Generic mfg.
Trial completion: Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Feb 24, 2013
P4, N=18, Completed, Sponsor: Mayo Clinic
N=40 --> 18 Recruiting --> Completed
- | Acetavance (acetaminophen) / Mallinckrodt
New P4 trial: IV Acetaminophen for Postoperative Analgesia (clinicaltrials.gov) - Feb 21, 2013
P4, N=224, Recruiting, Sponsor: North Shore Long Island Jewish Health System
- Enrollment closed: Cluster Randomised Trial of Improved Sanitation in Rural Orissa, India (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=100, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
Recruiting --> Completed Recruiting --> Active, not recruiting
- Enrollment closed: Healing Touch or Guided Imagery In Treating Pain, Fatigue, Nausea, and Anxiety in Patients Undergoing Chemotherapy (clinicaltrials.gov) - Feb 21, 2013
P=N/A, N=300, Active, not recruiting, Sponsor: Comprehensive Cancer Center of Wake Forest University
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- bisacodyl / Generic mfg.
Trial completion: Bisacodyl Use in the Post-operative Care of Obstetrical/Gynecological (OB/GYN) Patients (clinicaltrials.gov) - Feb 17, 2013
P2, N=285, Completed, Sponsor: The Cooper Health System
Recruiting --> Active, not recruiting Recruiting --> Completed