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93 Companies |
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118 Products |
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118 Products |
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88 Mechanisms of Action |
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3 Trials |
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1622 News |
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- tigecycline / Generic mfg.
Enrollment change: Pharmacokinetics and Safety of Tigecycline in the Treatment of Clostridium Difficile Associated Diarrhea (CDAD) (clinicaltrials.gov) - Jul 21, 2013
P=N/A, N=10, Completed, Sponsor: Gary E. Stein, Pharm.D.
N=20 --> 10
- tigecycline / Generic mfg.
Trial completion: Pharmacokinetics and Safety of Tigecycline in the Treatment of Clostridium Difficile Associated Diarrhea (CDAD) (clinicaltrials.gov) - Jul 21, 2013
P=N/A, N=10, Completed, Sponsor: Gary E. Stein, Pharm.D.
N=20 --> 10 Recruiting --> Completed
- morphine sulphate / Generic mfg.
Trial completion: Comparing the Analgesic Effect of Intravenous Acetaminophen and Morphine on Patients With Renal Colic Pain Reffering to the Emergency Department: A Randomized Controlled Trial (clinicaltrials.gov) - Jul 19, 2013
P2, N=124, Completed, Sponsor: Seyed Mehdi Pourafzali
Recruiting --> Completed Not yet recruiting --> Completed
- ||||| Resolor (prucalopride) / J&J, Takeda
New P4 trial, HEOR: An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation (clinicaltrials.gov) - Jul 16, 2013
P4, N=150, Completed, Sponsor: Janssen Korea, Ltd., Korea
- Enrollment open: Resistance of Helicobacter Pylori to Antibiotics in Children (clinicaltrials.gov) - Jul 15, 2013
P=N/A, N=100, Recruiting, Sponsor: HaEmek Medical Center, Israel
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
New P3 trial: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Jul 15, 2013
P3, N=44, Terminated, Sponsor: Cubist Pharmaceuticals
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
New P3 trial: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Jul 15, 2013
P3, N=49, Terminated, Sponsor: Cubist Pharmaceuticals
- || bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
New P3 trial: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Jul 15, 2013
P3, N=61, Terminated, Sponsor: Cubist Pharmaceuticals
- |||| Resolor (prucalopride) / J&J, Takeda
Trial completion, HEOR: An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation (clinicaltrials.gov) - Jul 14, 2013
P4, N=150, Completed, Sponsor: Janssen Korea, Ltd., Korea
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- ||||| Viberzi (eluxadoline) / AbbVie
Enrollment closed: Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) (clinicaltrials.gov) - Jul 14, 2013
P3, N=1125, Active, not recruiting, Sponsor: Furiex Pharmaceuticals, Inc
Not yet recruiting --> Completed Recruiting --> Active, not recruiting
- | Amitiza (lubiprostone) / Takeda, Mallinckrodt
Trial completion: Intestinal Microecology in Chronic Constipation (clinicaltrials.gov) - Jul 14, 2013
P1, N=21, Completed, Sponsor: Mayo Clinic
Recruiting --> Active, not recruiting Terminated --> Completed
- ||| Enrollment change: POCone-UBiT-IR300 Pediatric Comparison Study (clinicaltrials.gov) - Jul 12, 2013
P4, N=99, Completed, Sponsor: Otsuka America Pharmaceutical
Terminated --> Completed N=60 --> 99
- |||| Trial completion: POCone-UBiT-IR300 Pediatric Comparison Study (clinicaltrials.gov) - Jul 12, 2013
P4, N=99, Completed, Sponsor: Otsuka America Pharmaceutical
N=60 --> 99 Active, not recruiting --> Completed
- ondansetron / Generic mfg., doxylamine/pyridoxine / Generic mfg.
Trial initiation date: Ondansetron VS Doxylamine and Pyridoxine in Treating Nausea of Pregnancy (clinicaltrials.gov) - Jul 10, 2013
P=N/A, N=36, Completed, Sponsor: United States Naval Medical Center, San Diego
Active, not recruiting --> Completed Initiation date: Apr 2012 --> Oct 2012
- ondansetron / Generic mfg., doxylamine/pyridoxine / Generic mfg.
Trial completion: Ondansetron VS Doxylamine and Pyridoxine in Treating Nausea of Pregnancy (clinicaltrials.gov) - Jul 10, 2013
P=N/A, N=36, Completed, Sponsor: United States Naval Medical Center, San Diego
Initiation date: Apr 2012 --> Oct 2012 Recruiting --> Completed
- | ondansetron / Generic mfg.
New P4 trial: The Effect of Combining Aprepitant With Ondansetron in High-risk Patients for Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jul 9, 2013
P4, N=125, Completed, Sponsor: Yonsei University
- |||||||||| elobixibat (A3309) / Albireo, Ajinomoto, Ferring
New P3 trial: Safety and Tolerability Extension Trial for Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) - Jul 8, 2013
P3, N=900, Enrolling by invitation, Sponsor: Ferring Pharmaceuticals
- ondansetron / Generic mfg.
Trial completion: The Effect of Combining Aprepitant With Ondansetron in High-risk Patients for Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jul 7, 2013
P4, N=125, Completed, Sponsor: Yonsei University
Recruiting --> Completed Not yet recruiting --> Completed
- dronabinol oral / Generic mfg.
Trial completion: Delta-pain: Efficacy Study of Δ9-THC to Treat Chronic Abdominal Pain (clinicaltrials.gov) - Jul 7, 2013
P2, N=24, Completed, Sponsor: Radboud University
Not yet recruiting --> Completed Recruiting --> Completed
- Emestop (ramosetron hydrochloride) / Samyang Group
Enrollment open: Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jul 1, 2013
P2, N=96, Recruiting, Sponsor: Seoul National University Hospital
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Children Immune Functions (clinicaltrials.gov) - Jun 30, 2013
P=N/A, N=374, Completed, Sponsor: Nestlé
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | New P1/2 trial: Effect of TU-100 in Patients With Irritable Bowel Syndrome (IBS) (clinicaltrials.gov) - Jun 30, 2013
P1/2, N=40, Recruiting, Sponsor: Tsumura USA
- megestrol / Generic mfg., mirtazapine / Generic mfg.
Trial initiation date: Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite (clinicaltrials.gov) - Jun 27, 2013
P2, N=0, Withdrawn, Sponsor: Washington University School of Medicine
Active, not recruiting --> Completed Initiation date: Apr 2012 --> Sep 2013
- || oxycodone/naloxone ER / Generic mfg.
Trial initiation date, HEOR: Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives (clinicaltrials.gov) - Jun 26, 2013
P=N/A, N=200, Recruiting, Sponsor: Mundipharma AB
Initiation date: Apr 2012 --> Sep 2013 Initiation date: Mar 2013 --> Jun 2013
- |||| lansoprazole / Generic mfg.
Enrollment open: High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication (clinicaltrials.gov) - Jun 26, 2013
P4, N=118, Recruiting, Sponsor: Mahidol University
Initiation date: Mar 2013 --> Jun 2013 Not yet recruiting --> Recruiting
- ||| oxycodone/naloxone ER / Generic mfg.
Enrollment open, HEOR: Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives (clinicaltrials.gov) - Jun 26, 2013
P=N/A, N=200, Recruiting, Sponsor: Mundipharma AB
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial termination: Palonosetron for the Treatment of Nausea and Vomiting in Terminally Ill Patients (clinicaltrials.gov) - Jun 25, 2013
P2, N=3, Terminated, Sponsor: University of Michigan Cancer Center
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated; site terminated due to lack of enrollment
- Enrollment change: Palonosetron for the Treatment of Nausea and Vomiting in Terminally Ill Patients (clinicaltrials.gov) - Jun 25, 2013
P2, N=3, Terminated, Sponsor: University of Michigan Cancer Center
Active, not recruiting --> Terminated; site terminated due to lack of enrollment N=35 --> 3
- ||||| lansoprazole / Generic mfg.
New P4 trial: High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication (clinicaltrials.gov) - Jun 25, 2013
P4, N=118, Recruiting, Sponsor: Mahidol University
- ||| Clinical: Efficacy Study of Ginger (Zingiber Officinale) Extract "Ginpax" to Manage Nausea in Cancer Patients Receiving High Emetogenic Treatments and Standard Anti-emetogenic Therapy (clinicaltrials.gov) - Jun 24, 2013
P=N/A, N=250, Recruiting, Sponsor: Helsinn Healthcare SA
- Enrollment open: Perineal Self-Acupressure (clinicaltrials.gov) - Jun 23, 2013
P=N/A, N=100, Recruiting, Sponsor: University of California, Los Angeles
N=35 --> 3 Not yet recruiting --> Recruiting
- haloperidol / Generic mfg.
Trial withdrawal: Evidence of Haloperidol Absorption After Topical Administration (clinicaltrials.gov) - Jun 23, 2013
P0, N=0, Withdrawn, Sponsor: Eric E. Prommer
Not yet recruiting --> Recruiting Recruiting --> Withdrawn
- ||| Enrollment open: Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children (clinicaltrials.gov) - Jun 21, 2013
P=N/A, N=106, Recruiting, Sponsor: Aghia Sophia Children's Hospital of Athens
Recruiting --> Withdrawn Not yet recruiting --> Recruiting
- erythromycin / Generic mfg.
Enrollment change: Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa (clinicaltrials.gov) - Jun 20, 2013
P2, N=29, Completed, Sponsor: New York State Psychiatric Institute
Not yet recruiting --> Recruiting N=65 --> 29
- | bisacodyl / Generic mfg.
New P2 trial: Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003) (clinicaltrials.gov) - Jun 20, 2013
P2, N=67, Completed, Sponsor: Merck
- Resolor (prucalopride) / J&J, Takeda
Trial withdrawal: A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation (clinicaltrials.gov) - Jun 17, 2013
P4, N=0, Withdrawn, Sponsor: Janssen Pharmaceutica
N=65 --> 29 Not yet recruiting --> Withdrawn
- Resolor (prucalopride) / J&J, Takeda
Enrollment change: A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation (clinicaltrials.gov) - Jun 17, 2013
P4, N=0, Withdrawn, Sponsor: Janssen Pharmaceutica
Not yet recruiting --> Withdrawn N=3000 --> 0
- |||||||||| Linzess (linaclotide) / Astellas, Ironwood Pharma, AbbVie
New P3 trial: A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) (clinicaltrials.gov) - Jun 17, 2013
P3, N=800, Recruiting, Sponsor: AstraZeneca
- ||||| New P4 trial: A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia (clinicaltrials.gov) - Jun 16, 2013
P4, N=461, Completed, Sponsor: Johnson & Johnson Pte Ltd
- bisacodyl / Generic mfg.
New P4 trial, Surgery: Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery (clinicaltrials.gov) - Jun 16, 2013
P4, N=45, Completed, Sponsor: Oslo University Hospital
- Trial completion: Milk Ingredients and Resistance Against E-coli-induced GastroEnteritis (MIRAGE) (clinicaltrials.gov) - Jun 12, 2013
P=N/A, N=60, Completed, Sponsor: NIZO Food Research
N=3000 --> 0 Active, not recruiting --> Completed
- |||||| Enrollment open: Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study (clinicaltrials.gov) - Jun 12, 2013
P3, N=1100, Recruiting, Sponsor: Reckitt Benckiser Healthcare (UK) Limited
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood (clinicaltrials.gov) - Jun 10, 2013
P4, N=90, Completed, Sponsor: Medical University of Warsaw
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial withdrawal: Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting (clinicaltrials.gov) - Jun 10, 2013
P=N/A, N=0, Withdrawn, Sponsor: Stanford University
Recruiting --> Completed Recruiting --> Withdrawn
- Enrollment change: Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and Vomiting (clinicaltrials.gov) - Jun 10, 2013
P=N/A, N=0, Withdrawn, Sponsor: Stanford University
Recruiting --> Withdrawn N=35 --> 0
- | dexamethasone / Generic mfg., ondansetron / Generic mfg.
New P4 trial, Surgery, Bariatric surgery: Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jun 10, 2013
P4, N=120, Recruiting, Sponsor: Hopital Foch
- dexamethasone / Generic mfg., ondansetron / Generic mfg.
Enrollment open, Surgery, Bariatric surgery: Dexamethasone and Ondansetron Versus Placebo for Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jun 8, 2013
P4, N=120, Recruiting, Sponsor: Hopital Foch
N=35 --> 0 Not yet recruiting --> Recruiting
- | Emend intravenous (fosaprepitant) / Merck (MSD), Ono Pharma
New P2b trial, Metastases: Fosaprepitant for N/V With High-dose Interleukin-2 for Metastatic Melanoma and Renal Cell Carcinoma (clinicaltrials.gov) - Jun 6, 2013
P2b, N=22, Recruiting, Sponsor: St. Louis University
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Enrollment change: C-IBS: Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Jun 6, 2013
P=N/A, N=37, Completed, Sponsor: Mark Pimentel, MD
Not yet recruiting --> Recruiting N=89 --> 37
- | Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Trial completion: C-IBS: Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome (clinicaltrials.gov) - Jun 6, 2013
P=N/A, N=37, Completed, Sponsor: Mark Pimentel, MD
N=89 --> 37 Active, not recruiting --> Completed