Signs and Symptoms, Digestive News - LARVOL Sigma

Signs and Symptoms, Digestive

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88 Mechanisms of Action

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|||||||||| Trial completion: Defining Central Circuits of Pain (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=60, Completed, Sponsor: Massachusetts General Hospital
Recruiting --> Completed

|||||||||| Trial completion: Comparing Two Group Therapy Treatments for Binge Eating Disorder (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=101, Completed, Sponsor: Stanford University
Recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Ginger Control of Chemotherapy Induced Nausea and Vomiting (clinicaltrials.gov) - Feb 22, 2014
P2, N=180, Completed, Sponsor: National Center for Complementary and Alternative Medicine (NCCAM)
No longer recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Written Self-disclosure for Youth Abdominal Pain (clinicaltrials.gov) - Feb 22, 2014
P2/3, N=160, Completed, Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: Cognitive Therapy for Binge-Eating Disorder (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=60, Completed, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Treatment of Binge Eating Disorder (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=200, Completed, Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
No longer recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Meditation-Based Treatment for Binge Eating Disorder (clinicaltrials.gov) - Feb 22, 2014
P2/3, N=160, Completed, Sponsor: National Center for Complementary and Alternative Medicine (NCCAM)
No longer recruiting --> Completed No longer recruiting --> Completed

|||||||||| Enrollment change: Correlation of Location of Abdominal Tenderness With Acute CT Abnormalities in Emergency Department Patients (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=102, Completed, Sponsor: Duke University
No longer recruiting --> Completed N=2400 --> 102

|||||||||| Trial completion: Correlation of Location of Abdominal Tenderness With Acute CT Abnormalities in Emergency Department Patients (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=102, Completed, Sponsor: Duke University
N=2400 --> 102 Active, not recruiting --> Completed

||||||||||  esomeprazole / Generic mfg.
Trial completion:  Proton Pump Inhibitor Treatment Stop (clinicaltrials.gov) -  Feb 22, 2014
P4, N=171, Completed,  Sponsor: Odense University Hospital
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  cefixime / Generic mfg., temozolomide / Generic mfg.
Trial completion:  N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma (clinicaltrials.gov) -  Feb 22, 2014
P1, N=30, Completed,  Sponsor: Children's Hospital Los Angeles
No longer recruiting --> Completed Active, not recruiting --> Completed

||||||||||  irinotecan / Generic mfg., celecoxib oral / Generic mfg.
Trial completion, Combination therapy, Metastases:  Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer (clinicaltrials.gov) -  Feb 22, 2014
P1, N=2, Completed,  Sponsor: Roswell Park Cancer Institute
Active, not recruiting --> Completed Recruiting --> Completed

||||||||||  Enbrel (etanercept) / Pfizer, Amgen
Trial completion, Metastases:  Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer (clinicaltrials.gov) -  Feb 22, 2014
P3, N=0, Completed,  Sponsor: Mayo Clinic
Recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: Acupressure in Treating Nausea in Women Receiving Combination Chemotherapy for Breast Cancer (clinicaltrials.gov) - Feb 22, 2014
P3, N=57, Completed, Sponsor: M.D. Anderson Cancer Center
Active, not recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=34, Completed, Sponsor: National Institutes of Health Clinical Center (CC)
No longer recruiting --> Completed No longer recruiting --> Completed

|||||||||| Trial completion: Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction (clinicaltrials.gov) - Feb 19, 2014
P1/2, N=0, Completed, Sponsor: Northwestern University
No longer recruiting --> Completed Active, not recruiting --> Completed

|||||||||| Trial completion: Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction (clinicaltrials.gov) - Feb 19, 2014
P1/2, N=0, Completed, Sponsor: Northwestern University
Active, not recruiting --> Completed Active, not recruiting --> Completed

||||||||||  megestrol / Generic mfg.
Trial completion:  The Safety and Effectiveness of Megace in HIV-Infected Women (clinicaltrials.gov) -  Feb 19, 2014
P4, N=40, Completed,  Sponsor: Bristol-Myers Squibb
Active, not recruiting --> Completed No longer recruiting --> Completed

||||||||||  megestrol / Generic mfg.
Trial completion:  A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition (clinicaltrials.gov) -  Feb 19, 2014
P2, N=0, Completed,  Sponsor: Bristol-Myers Squibb
No longer recruiting --> Completed No longer recruiting --> Completed

||||||||||  megestrol / Generic mfg.
Trial completion:  A Study Comparing Megestrol Acetate at 800 mg/Day, and Placebo in AIDS Patients With Anorexia and Cachexia (clinicaltrials.gov) -  Feb 19, 2014
P3, N=0, Completed,  Sponsor: Bristol-Myers Squibb
No longer recruiting --> Completed No longer recruiting --> Completed

||||||||||  Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Enrollment closed:  TARGET3t: Irritable Bowel Syndrome With Diarrhea (IBS-D) Rifaximin Re-Treatment Study (clinicaltrials.gov) -  Feb 19, 2014
P3, N=800, Active, not recruiting,  Sponsor: Salix Pharmaceuticals
No longer recruiting --> Completed Recruiting --> Active, not recruiting

||||||||||  RotaTeq (Live attenuated pentavalent Rotavirus oral vaccine) / Merck (MSD)
Enrollment open:  An Alternate Dosing Schedule for Pentavalent Rotavirus Vaccine (RotaTeq) (clinicaltrials.gov) -  Feb 16, 2014
P4, N=60, Recruiting,  Sponsor: Emmanuel Walter
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting

|||||||||| Trial withdrawal: Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy (clinicaltrials.gov) - Feb 11, 2014
P2, N=0, Withdrawn, Sponsor: Stanford University
Not yet recruiting --> Recruiting Not yet recruiting --> Withdrawn

|||||||||| Enrollment change: Probiotic Supplementation in Preventing Treatment-Related Diarrhea in Patients With Cancer Undergoing Chemotherapy (clinicaltrials.gov) - Feb 11, 2014
P2, N=0, Withdrawn, Sponsor: Stanford University
Not yet recruiting --> Withdrawn N=30 --> 0

|||||||||| Trial termination: RESTORS: High Amylose Maize Starch for Treatment of Cholera (clinicaltrials.gov) - Feb 10, 2014
P=N/A, N=106, Terminated, Sponsor: PATH
N=30 --> 0 Recruiting --> Terminated; The study was closed early due to slow enrollment.

|||||||||| Enrollment change: RESTORS: High Amylose Maize Starch for Treatment of Cholera (clinicaltrials.gov) - Feb 10, 2014
P=N/A, N=106, Terminated, Sponsor: PATH
Recruiting --> Terminated; The study was closed early due to slow enrollment. N=150 --> 106

||||||||||  ondansetron / Generic mfg., dronabinol oral / Generic mfg.
Enrollment closed:  Prevention of Postoperative Nausea and Vomiting in Surgical Patients (clinicaltrials.gov) -  Feb 6, 2014
P=N/A, N=190, Active, not recruiting,  Sponsor: Department of Veterans Affairs
N=150 --> 106 Recruiting --> Active, not recruiting

|||||||||| Trial completion: A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia (clinicaltrials.gov) - Feb 6, 2014
P4, N=461, Completed, Sponsor: Johnson & Johnson Pte Ltd
Recruiting --> Active, not recruiting Recruiting --> Completed

|||||||||| Enrollment closed, Head-to-Head: Low Dose Versus Usual Dose Dexamethasone for Symptom Control in Children Undergoing Cranial or Craniospinal Radiation (clinicaltrials.gov) - Feb 4, 2014
P3, N=64, Active, not recruiting, Sponsor: The Hospital for Sick Children
Recruiting --> Completed Recruiting --> Active, not recruiting

||||||||||  piromelatine (Neu P11) / Neurim
Trial completion:  The Effect of Neu-P11 on Symptoms in Patients With D-IBS (clinicaltrials.gov) -  Feb 3, 2014
P=N/A, N=40, Completed,  Sponsor: Ludwig-Maximilians - University of Munich
Recruiting --> Active, not recruiting Enrolling by invitation --> Completed

||||||||||  Viberzi (eluxadoline) / AbbVie
Trial completion:  Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) (clinicaltrials.gov) -  Feb 3, 2014
P3, N=1150, Completed,  Sponsor: Furiex Pharmaceuticals, Inc
Enrolling by invitation --> Completed Active, not recruiting --> Completed

|||||||||| New P4 trial: Proton Pump Inhibitors and Gastrointestinal Symptoms (clinicaltrials.gov) - Feb 2, 2014
P4, N=100, Completed, Sponsor: Federico II University

||||||||||  Relistor (methylnaltrexone bromide) / Ono Pharma, Bausch Health
Enrollment change:  Methylnaltrexone for Opioid-induced Constipation in Cancer Patients (clinicaltrials.gov) -  Feb 1, 2014
P2, N=12, Completed,  Sponsor: University of Vermont
Active, not recruiting --> Completed N=17 --> 12

||||||||||  Relistor (methylnaltrexone bromide) / Ono Pharma, Bausch Health
Trial completion:  Methylnaltrexone for Opioid-induced Constipation in Cancer Patients (clinicaltrials.gov) -  Feb 1, 2014
P2, N=12, Completed,  Sponsor: University of Vermont
N=17 --> 12 Recruiting --> Completed

||||||||||  megestrol / Generic mfg., mirtazapine / Generic mfg.
Trial withdrawal:  Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite (clinicaltrials.gov) -  Jan 30, 2014
P2, N=0, Withdrawn,  Sponsor: Washington University School of Medicine
Recruiting --> Completed Not yet recruiting --> Withdrawn

||||||||||  megestrol / Generic mfg., mirtazapine / Generic mfg.
Enrollment change:  Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite (clinicaltrials.gov) -  Jan 30, 2014
P2, N=0, Withdrawn,  Sponsor: Washington University School of Medicine
Not yet recruiting --> Withdrawn N=106 --> 0

||||||||||  Emend intravenous (fosaprepitant) / Merck (MSD), Ono Pharma
Enrollment closed:  Fosaprepitant in Patients Receiving Ifosfamide-based Regimen (clinicaltrials.gov) -  Jan 30, 2014
P=N/A, N=40, Active, not recruiting,  Sponsor: M.D. Anderson Cancer Center
N=106 --> 0 Recruiting --> Active, not recruiting

|||||||||| New P2/3 trial: Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion (clinicaltrials.gov) - Jan 29, 2014
P2/3, N=24, Recruiting, Sponsor: Atlantia Food Clinical Trials

||||||||||  elobixibat (A3309) / Albireo, Ajinomoto, Ferring
Trial suspension:  Efficacy and Safety Trial of Elobixibat in Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) -  Jan 28, 2014
P3, N=840, Suspended,  Sponsor: Ferring Pharmaceuticals
Recruiting --> Active, not recruiting Recruiting --> Suspended

||||||||||  elobixibat (A3309) / Albireo, Ajinomoto, Ferring
Trial suspension:  26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation (clinicaltrials.gov) -  Jan 28, 2014
P3, N=840, Suspended,  Sponsor: Ferring Pharmaceuticals
Recruiting --> Suspended Recruiting --> Suspended

|||||||||| Enrollment open: Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome (clinicaltrials.gov) - Jan 26, 2014
P2, N=38, Recruiting, Sponsor: Ferring Pharmaceuticals
Recruiting --> Suspended Not yet recruiting --> Recruiting

|||||||||| Trial completion: Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy (clinicaltrials.gov) - Jan 26, 2014
P=N/A, N=393, Completed, Sponsor: Atlantic Health System
Not yet recruiting --> Recruiting Recruiting --> Completed

||||||||||  fosaprepitant / Generic mfg.
Trial completion:  Fosaprepitant (MK-0517, EMEND (clinicaltrials.gov) -  Jan 22, 2014
P2, N=111, Completed,  Sponsor: Merck Sharp & Dohme Corp.
Recruiting --> Completed Recruiting --> Completed

||||||||||  irinotecan / Generic mfg.
Enrollment change:  Prevention of Irinotecan Induced Diarrhea by Probiotics (clinicaltrials.gov) -  Jan 21, 2014
P3, N=46, Completed,  Sponsor: Monsea Ltd.
Recruiting --> Completed N=220 --> 46

||||||||||  ondansetron / Generic mfg.
Enrollment open:  Ondangapi: Efficacy of Ondansetron on Vomiting Due to Acute Gastroenteritis in Pediatric During Winter (clinicaltrials.gov) -  Jan 21, 2014
P3, N=500, Recruiting,  Sponsor: Assistance Publique - Hôpitaux de Paris
N=220 --> 46 Not yet recruiting --> Recruiting

||||||||||  irinotecan / Generic mfg.
Trial completion:  Prevention of Irinotecan Induced Diarrhea by Probiotics (clinicaltrials.gov) -  Jan 21, 2014
P3, N=46, Completed,  Sponsor: Monsea Ltd.
Not yet recruiting --> Recruiting Recruiting --> Completed

|||||||||| Enrollment change: A Closer Look at the Effect of Dextrose on Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jan 19, 2014
P=N/A, N=202, Completed, Sponsor: Loma Linda University
Recruiting --> Completed N=100 --> 202

|||||||||| Trial completion: A Closer Look at the Effect of Dextrose on Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jan 19, 2014
P=N/A, N=202, Completed, Sponsor: Loma Linda University
N=100 --> 202 Active, not recruiting --> Completed

|||||||||| Trial completion: Mesalazine for the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D) (clinicaltrials.gov) - Jan 15, 2014
P4, N=108, Completed, Sponsor: University of Nottingham
Active, not recruiting --> Completed Recruiting --> Completed

|||||||||| Trial completion: fMRI and Ghlrein in Obesity and Binge Eating Disorder (clinicaltrials.gov) - Jan 13, 2014
P=N/A, N=93, Completed, Sponsor: New York Obesity and Nutrition Research Center
Recruiting --> Completed Not yet recruiting --> Completed