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93 Companies |
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118 Products |
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118 Products |
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88 Mechanisms of Action |
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3 Trials |
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1622 News |
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- |||||||||| Sustol (granisetron ER) / Heron Therapeutics
New P3 trial: A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC (clinicaltrials.gov) - Apr 6, 2014
P3, N=1000, Recruiting, Sponsor: Heron Therapeutics
- |||||| Acofide (acotiamide) / Zeria, Astellas
Enrollment open, P3 data: Phase III, Long-term, Open-label Safety Study of Z-338 (clinicaltrials.gov) - Apr 3, 2014
P3, N=350, Recruiting, Sponsor: Zeria Pharmaceutical
Not yet recruiting --> Recruiting
- |||||| Ibodutant (MEN 15596) / Menarini
Enrollment open: IRIS-3: 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) (clinicaltrials.gov) - Apr 3, 2014
P3, N=500, Recruiting, Sponsor: Menarini Group
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Clinical: Edible Oils in the Treatment of Constipation of Hemodialysis Patients (clinicaltrials.gov) - Apr 2, 2014
P=N/A, N=50, Completed, Sponsor: Federal University of São Paulo
- |||||| Sustol (granisetron ER) / Heron Therapeutics
Enrollment open: A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC (clinicaltrials.gov) - Apr 2, 2014
P3, N=1000, Recruiting, Sponsor: Heron Therapeutics
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Enrollment closed: Characteristics and Importance of Physical Activity in Women With Anorexia Nervosa (clinicaltrials.gov) - Apr 1, 2014
P=N/A, N=80, Active, not recruiting, Sponsor: New York State Psychiatric Institute
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- ||||||| Amitiza (lubiprostone) / Takeda, Mallinckrodt
Trial completion: Evaluation of Clinical Equivalence Between Two Lubiprostone Products in the Treatment of Chronic Idiopathic Constipation (clinicaltrials.gov) - Apr 1, 2014
P3, N=909, Completed, Sponsor: Dr. Reddy's Laboratories Limited
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Enrollment change: Clinical Evaluation of Ultrasonic Hydration Monitor for Infants (clinicaltrials.gov) - Mar 27, 2014
P=N/A, N=42, Completed, Sponsor: Artann Laboratories
Active, not recruiting --> Completed N=400 --> 42
- |||| Enrollment open: Efficacy and Safety of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders. (clinicaltrials.gov) - Mar 26, 2014
P2, N=400, Recruiting, Sponsor: Probi AB
N=400 --> 42 Not yet recruiting --> Recruiting
- | Dificid (fidaxomicin) / Merck (MSD), Astellas
Trial completion: Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD) (clinicaltrials.gov) - Mar 26, 2014
P2a, N=32, Completed, Sponsor: Optimer Pharmaceuticals
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- | Trial completion: Clinical Evaluation of Ultrasonic Hydration Monitor for Infants (clinicaltrials.gov) - Mar 26, 2014
P=N/A, N=42, Completed, Sponsor: Artann Laboratories
Active, not recruiting --> Completed Active, not recruiting --> Completed
- olanzapine / Generic mfg.
New P2 trial: Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving Chemotherapy (clinicaltrials.gov) - Mar 25, 2014
P2, N=20, Recruiting, Sponsor: Indiana University
- Trial completion: LRFC: Lactobacillus Reuteri DSM 17938 in Functional Constipation (clinicaltrials.gov) - Mar 25, 2014
P4, N=72, Completed, Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Active, not recruiting --> Completed Enrolling by invitation --> Completed
- olanzapine / Generic mfg.
Enrollment open: Pilot Study of Olanzapine and Aprepitant to Prevent Nausea and Vomiting in Children Receiving Chemotherapy (clinicaltrials.gov) - Mar 23, 2014
P2, N=20, Recruiting, Sponsor: Indiana University
Enrolling by invitation --> Completed Not yet recruiting --> Recruiting
- ||||||| Varubi (rolapitant oral) / TerSera Therap, GSK
Trial completion: Ph 3 Safety/Efficacy Study of Rolapitant for Prevention of CINV in Subjects Receiving Moderately Emetogenic Chemotherapy (clinicaltrials.gov) - Mar 23, 2014
P3, N=1369, Completed, Sponsor: Tesaro, Inc.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Nepadutant (MEN 11420) / Menarini
Trial completion: no-cry: Preliminary Efficacy and Safety Study of Oral Nepadutant in Infant Colic (clinicaltrials.gov) - Mar 23, 2014
P2, N=115, Completed, Sponsor: Menarini Group
Active, not recruiting --> Completed Recruiting --> Completed
- dexamethasone / Generic mfg., tropisetron / Generic mfg.
Enrollment open, Combination therapy: TEASP6PPONV: Transcutaneous Electrical Acupoint Stimulation of P6 to Prevent Postoperation Nausea and Vomiting (clinicaltrials.gov) - Mar 23, 2014
P=N/A, N=130, Recruiting, Sponsor: Huashan Hospital
Recruiting --> Completed Not yet recruiting --> Recruiting
- ||||||| Varubi (rolapitant oral) / TerSera Therap, GSK
Trial completion, CINV: Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy (clinicaltrials.gov) - Mar 23, 2014
P3, N=555, Completed, Sponsor: Tesaro, Inc.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Surgery, Bariatric surgery: Bariatric Surgery and Guided Self-help for Binge Eating Disorder (clinicaltrials.gov) - Mar 19, 2014
P=N/A, N=150, Recruiting, Sponsor: Imperial College London
- Enrollment closed: Outpatient Treatment of Constipation in Children (clinicaltrials.gov) - Mar 18, 2014
P=N/A, N=225, Active, not recruiting, Sponsor: Line Modin
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- Movicol (polyethylene glycol/sodium bicarbonate/sodium chloride/potassium chloride) / Mochida, Eisai, Norgine
Enrollment open: Maintenance Treatment for Children With Constipation (clinicaltrials.gov) - Mar 18, 2014
P=N/A, N=125, Recruiting, Sponsor: Line Modin
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- New P1/2 trial: Consumption of Milk Drink and Constipation (clinicaltrials.gov) - Mar 17, 2014
P1/2, N=49, Completed, Sponsor: Centro Universitário Univates
- recanaclotide (IW-9179) / Ironwood Pharma
Trial termination: Phase 2a Study of IW-9179 to Treat Functional Dyspepsia (clinicaltrials.gov) - Mar 17, 2014
P2, N=10, Terminated, Sponsor: Ironwood Pharmaceuticals, Inc.
Not yet recruiting --> Recruiting Recruiting --> Terminated; Slow enrollment
- recanaclotide (IW-9179) / Ironwood Pharma
Enrollment change: Phase 2a Study of IW-9179 to Treat Functional Dyspepsia (clinicaltrials.gov) - Mar 17, 2014
P2, N=10, Terminated, Sponsor: Ironwood Pharmaceuticals, Inc.
Recruiting --> Terminated; Slow enrollment N=80 --> 10
- Trial termination: Prevention of Narcotic-Induced Nausea (clinicaltrials.gov) - Mar 11, 2014
P=N/A, N=25, Terminated, Sponsor: Christiana Care Health Services
N=80 --> 10 Completed --> Terminated; Terminated: recruiting or enrolling participants has halted prematurely and will not resume; participants are no longer being examined or treated
- Enrollment change: Prevention of Narcotic-Induced Nausea (clinicaltrials.gov) - Mar 11, 2014
P=N/A, N=25, Terminated, Sponsor: Christiana Care Health Services
Completed --> Terminated; Terminated: recruiting or enrolling participants has halted prematurely and will not resume; participants are no longer being examined or treated N=164 --> 25
- ||| Enrollment closed: Effect of a Lacidofil® STRONG in Healthy Adults Taking Antibiotic Treatment (clinicaltrials.gov) - Mar 10, 2014
P1/2, N=160, Active, not recruiting, Sponsor: KGK Synergize Inc.
N=164 --> 25 Recruiting --> Active, not recruiting
- ||| Trial completion: AMPED Outcomes Registry of Post-ED Pain Management (clinicaltrials.gov) - Mar 10, 2014
P=N/A, N=843, Completed, Sponsor: Radnor Registry Research, Inc
Recruiting --> Active, not recruiting Recruiting --> Completed
- ||||| relenopride (YKP-GI) / SK Bio
New P2 trial: Efficacy and Safety of YKP10811 in Subjects With Irritable Bowel Syndrome With Constipation (clinicaltrials.gov) - Mar 6, 2014
P2, N=276, Recruiting, Sponsor: SK Chemicals Co.,Ltd.
- Clinical: Evaluation of a Multiple Behaviour Programme for Diarrhoea Management (clinicaltrials.gov) - Mar 5, 2014
P=N/A, N=640, Active, not recruiting, Sponsor: London School of Hygiene and Tropical Medicine
- Clinical: FAKT: Treatment of Eating Disorders by Physical Activity and Nutrition Counseling (clinicaltrials.gov) - Mar 4, 2014
P=N/A, N=150, Recruiting, Sponsor: Norwegian School of Sport Sciences
- || New P3 trial: Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea (clinicaltrials.gov) - Mar 4, 2014
P3, N=150, Recruiting, Sponsor: Sinaloa Pediatric Hospital
- Linzess (linaclotide) / Astellas, Ironwood Pharma, AbbVie
Clinical: Investigation of Linaclotide's Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients (clinicaltrials.gov) - Mar 3, 2014
P=N/A, N=45, Recruiting, Sponsor: Georgia Regents University
- ketamine / Generic mfg.
Trial completion, Surgery: Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery (clinicaltrials.gov) - Mar 3, 2014
P4, N=50, Completed, Sponsor: Yonsei University
Recruiting --> Completed Recruiting --> Completed
- Clinical: VEOLITH: Model-based Iterative Reconstruction (MB-IR VEOTM) in Ultra Low-dose Abdominal CT Versus Adaptative Statistical Iterative Reconstruction (ASIR): A Prospective Study for Acute Renal Colic (clinicaltrials.gov) - Mar 2, 2014
P=N/A, N=120, Completed, Sponsor: University Hospital, Clermont-Ferrand
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Trial termination: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=44, Terminated, Sponsor: Cubist Pharmaceuticals
Recruiting --> Completed Active, not recruiting --> Terminated; Due to difficulties with enrollment, the study was terminated early.
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Trial termination: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=49, Terminated, Sponsor: Cubist Pharmaceuticals
Active, not recruiting --> Terminated; Due to difficulties with enrollment, the study was terminated early. Active, not recruiting --> Terminated; Sponsor decision due to lack of enrollment.
- | bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Trial termination: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=61, Terminated, Sponsor: Cubist Pharmaceuticals
Active, not recruiting --> Terminated; Sponsor decision due to lack of enrollment. Active, not recruiting --> Terminated; Sponsor decision due to lack of enrollment.
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Enrollment change: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=44, Terminated, Sponsor: Cubist Pharmaceuticals
Active, not recruiting --> Terminated; Sponsor decision due to lack of enrollment. N=600 --> 44
- bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Enrollment change: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=49, Terminated, Sponsor: Cubist Pharmaceuticals
N=600 --> 44 N=600 --> 49
- | bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Enrollment change: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=61, Terminated, Sponsor: Cubist Pharmaceuticals
N=600 --> 49 N=600 --> 61
- ||||| bevenopran (CB-5945) / Eli Lilly, Merck (MSD)
Enrollment closed: Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation (clinicaltrials.gov) - Mar 2, 2014
P3, N=1400, Active, not recruiting, Sponsor: Cubist Pharmaceuticals
N=600 --> 61 Recruiting --> Active, not recruiting
- Clinical: Probiotics for Prevention of Antibiotic Associated Diarrhea and Clostridium Difficile Associated Disease (clinicaltrials.gov) - Feb 27, 2014
P=N/A, N=290, Recruiting, Sponsor: Rutgers, The State University of New Jersey
- Trial completion: An Efficacy Trial of a Gravity Fed Household Water Treatment Device as a Delivery System for Zinc (clinicaltrials.gov) - Feb 26, 2014
P=N/A, N=270, Completed, Sponsor: Wageningen University
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- |||| elsiglutide (ZP1846) / Zealand Pharma
Trial completion: Proof-of-Concept Study in Cancer Patients to Assess Efficacy of Elsiglutide in Preventing Chemotherapy-Induced Diarrhea (clinicaltrials.gov) - Feb 26, 2014
P2, N=138, Completed, Sponsor: Helsinn Healthcare SA
Active, not recruiting --> Completed Recruiting --> Completed
- |||||||||| New P2/3 trial: A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation (clinicaltrials.gov) - Feb 25, 2014
P2/3, N=70, Recruiting, Sponsor: Atlantia Food Clinical Trials
- dexamethasone / Generic mfg., ondansetron / Generic mfg.
Trial completion: Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children (clinicaltrials.gov) - Feb 25, 2014
P4, N=300, Completed, Sponsor: Centre Hospitalier Universitaire Vaudois
Recruiting --> Completed Recruiting --> Completed
- | diazepam / Generic mfg.
Trial completion: Biofeedback for Dyssynergic Constipation (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=117, Completed, Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting --> Completed No longer recruiting --> Completed
- | Trial completion: Effectiveness of Biofeedback-Assisted Relaxation Training in Children With Eosinophilic Duodenitis (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=20, Completed, Sponsor: Children's Mercy Hospital Kansas City
No longer recruiting --> Completed No longer recruiting --> Completed
- | venlafaxine / Generic mfg.
Trial completion: Serotonin Effect in Functional Dyspepsia (clinicaltrials.gov) - Feb 22, 2014
P=N/A, N=300, Completed, Sponsor: Radboud University
No longer recruiting --> Completed Recruiting --> Completed