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93 Companies |
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118 Products |
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118 Products |
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88 Mechanisms of Action |
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3 Trials |
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1622 News |
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- |||| Resolor (prucalopride) / J&J, Takeda
Enrollment open, Combination therapy: Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation (clinicaltrials.gov) - Jan 22, 2015
P4, N=280, Recruiting, Sponsor: Xian-Janssen Pharmaceutical Ltd.
Not yet recruiting --> Recruiting
- ||||| Ibodutant (MEN 15596) / Menarini
Enrollment closed: IRIS-3: 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) (clinicaltrials.gov) - Jan 22, 2015
P3, N=500, Active, not recruiting, Sponsor: Menarini Group
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- |||||||||| New P3 trial: Efficacy and Safety Study of Loperamide Hydrochloride/Simethicone Chewable Tablet in Treatment of Acute Diarrhea With Abdominal Discomfort and Flatulence (clinicaltrials.gov) - Jan 18, 2015
P3, N=217, Completed, Sponsor: Xian-Janssen Pharmaceutical Ltd.
- ||||| Dificid (fidaxomicin) / Merck (MSD), Astellas
Enrollment closed: DEFLECT-1: Safety and Efficacy of Fidaxomicin Versus Placebo for Prophylaxis Against Clostridium Difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (MK-5119-001) (clinicaltrials.gov) - Jan 18, 2015
P3, N=600, Active, not recruiting, Sponsor: Optimer Pharmaceuticals
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- || Trial primary completion date: Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=106, Recruiting, Sponsor: Aghia Sophia Children's Hospital of Athens
Recruiting --> Active, not recruiting Trial primary completion date: Mar 2014 --> Dec 2016
- ||||||| Trial completion: A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation (clinicaltrials.gov) - Jan 15, 2015
P2/3, N=70, Completed, Sponsor: Atlantia Food Clinical Trials
Trial primary completion date: Mar 2014 --> Dec 2016 Recruiting --> Completed
- || Trial completion, Trial primary completion date: Study of Pylopass Versus Placebo in Subjects Who Are Helicobacter Pylori Carriers and With Mild Indigestion (clinicaltrials.gov) - Jan 15, 2015
P2/3, N=24, Completed, Sponsor: Atlantia Food Clinical Trials
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2014 --> Dec 2014
- | New P4 trial: Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis (clinicaltrials.gov) - Jan 13, 2015
P4, N=110, Not yet recruiting, Sponsor: Rabin Medical Center
- | New P4 trial: Urotherapy vs. Urotherapy With Constipation Treatment for Children With Lower Urinary Tract Dysfunction (clinicaltrials.gov) - Jan 13, 2015
P4, N=110, Not yet recruiting, Sponsor: Rabin Medical Center
- |||||||||| Barhemsys (intravenous amisulpride) / Acacia Pharma
New P3 trial: Phase IIIb Study of APD421 in Combination as PONV Prophylaxis (clinicaltrials.gov) - Jan 13, 2015
P3, N=1100, Not yet recruiting, Sponsor: Acacia Pharma Ltd
- | Enrollment closed, Trial primary completion date: CONSTIMOD: Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation (clinicaltrials.gov) - Jan 13, 2015
P2, N=20, Active, not recruiting, Sponsor: University Hospital, Bordeaux
Recruiting --> Completed | Trial primary completion date: May 2014 --> Dec 2014 Recruiting --> Active, not recruiting | Trial primary completion date: May 2014 --> Nov 2013
- Bridion (sugammadex) / Merck (MSD)
Trial completion: Comparison of the Effects of Neostigmine With Sugammadex on Postoperative Nausea and Vomiting. (clinicaltrials.gov) - Jan 13, 2015
P4, N=98, Completed, Sponsor: T.C. ORDU ÜNİVERSİTESİ
Recruiting --> Active, not recruiting | Trial primary completion date: May 2014 --> Nov 2013 Recruiting --> Completed
- |||| Emestop (ramosetron hydrochloride) / Samyang Group
Trial completion, Trial primary completion date: Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting (clinicaltrials.gov) - Jan 13, 2015
P2, N=96, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Oct 2014
- |||| Linzess (linaclotide) / Astellas, Ironwood Pharma, AbbVie
Trial primary completion date: A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) (clinicaltrials.gov) - Jan 13, 2015
P3, N=800, Recruiting, Sponsor: AstraZeneca
Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Oct 2014 Trial primary completion date: Dec 2014 --> May 2015
- ||||||| Barhemsys (intravenous amisulpride) / Acacia Pharma
Trial completion: US Phase III Study of APD421 in PONV (clinicaltrials.gov) - Jan 12, 2015
P3, N=364, Completed, Sponsor: Acacia Pharma Ltd
Trial primary completion date: Dec 2014 --> May 2015 Recruiting --> Completed
- || ondansetron / Generic mfg., temozolomide / Generic mfg.
Trial primary completion date, Combination therapy, CINV: Emend and Ondansetron Compared to Ondansetron Alone to Prevent CINV in Glioma Patients Receiving Temozolomide (clinicaltrials.gov) - Jan 9, 2015
P2, N=136, Recruiting, Sponsor: Katy Peters
Recruiting --> Completed Trial primary completion date: Dec 2014 --> Jun 2016
- lorazepam / Generic mfg., haloperidol / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Randomized Trial of the Effectiveness of Topical "ABH Gel" vs. Placebo in Cancer Patients With Nausea (clinicaltrials.gov) - Jan 9, 2015
P=N/A, N=25, Completed, Sponsor: Virginia Commonwealth University
Trial primary completion date: Dec 2014 --> Jun 2016 Active, not recruiting --> Completed | N=20 --> 25 | Trial primary completion date: Mar 2014 --> May 2013
- Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health, Norgine, ASKA Pharma
Enrollment closed: Efficacy of Rifaximin in Preventing Campylobacteriosis (clinicaltrials.gov) - Jan 8, 2015
P2/3, N=28, Active, not recruiting, Sponsor: Johns Hopkins Bloomberg School of Public Health
Active, not recruiting --> Completed | N=20 --> 25 | Trial primary completion date: Mar 2014 --> May 2013 Recruiting --> Active, not recruiting
- | Trial initiation date: Impact of Laxative Therapy With Lactulose in the Evolution of Organ Dysfunction in Critically Ill Patients. (clinicaltrials.gov) - Jan 7, 2015
P3, N=88, Completed, Sponsor: Federal University of São Paulo
Recruiting --> Active, not recruiting Initiation date: May 2009 --> Sep 2008
- Clinical: Oxytocin and Incitement to Use Olfactory Stimuli in Restrictive Anorexia Nervosa (clinicaltrials.gov) - Jan 7, 2015
P=N/A, N=60, Not yet recruiting, Sponsor: Fondation Lenval
- Trial completion, Trial primary completion date: Gut Hormone, Nociceptors, Neurotrophic Factors Expression in Functional Dyspepsia (clinicaltrials.gov) - Jan 7, 2015
P=N/A, N=314, Completed, Sponsor: Seoul National University Bundang Hospital
Initiation date: May 2009 --> Sep 2008 Recruiting --> Completed | Trial primary completion date: Jul 2015 --> Jun 2014
- Trial completion: Eating Behavior in Adolescents (clinicaltrials.gov) - Jan 6, 2015
P=N/A, N=301, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting --> Completed | Trial primary completion date: Jul 2015 --> Jun 2014 Active, not recruiting --> Completed
- || dexmedetomidine / Generic mfg.
Clinical: Adjuvant Effect of Dexmedetomidine in Ultrasound (USG) Guided Transvers Abdominis Plane Block (clinicaltrials.gov) - Jan 6, 2015
P3, N=60, Active, not recruiting, Sponsor: Kırıkkale University
- Clinical: Web-based Management of Pediatric Functional Abdominal Pain (clinicaltrials.gov) - Dec 30, 2014
P=N/A, N=300, Recruiting, Sponsor: Vanderbilt University
- ||||| Enrollment change: Effect of Probiotic Formula on Reducing the Risk for Antibiotic-associated Diarrhoea (clinicaltrials.gov) - Dec 24, 2014
P2/3, N=250, Active, not recruiting, Sponsor: Danisco
Active, not recruiting --> Completed N=400 --> 250
- Trial completion, Trial primary completion date: The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation (clinicaltrials.gov) - Dec 24, 2014
P2, N=1050, Completed, Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
N=400 --> 250 Active, not recruiting --> Completed | Trial primary completion date: Jun 2014 --> Oct 2014
- HEOR: Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation (clinicaltrials.gov) - Dec 22, 2014
P=N/A, N=50, Recruiting, Sponsor: Hacettepe University
- |||| relenopride (YKP-GI) / SK Bio
Trial completion, Trial primary completion date: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation (clinicaltrials.gov) - Dec 19, 2014
P2, N=334, Completed, Sponsor: SK Life Science
Active, not recruiting --> Completed | Trial primary completion date: Jun 2014 --> Oct 2014 Active, not recruiting --> Completed | Trial primary completion date: May 2015 --> Sep 2014
- |||||||||| Ibodutant (MEN 15596) / Menarini
New P3 trial: IRIS-05: 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) (clinicaltrials.gov) - Dec 19, 2014
P3, N=500, Recruiting, Sponsor: Menarini Group
- Enrollment change, Combination therapy: Prophylactic Subhypnotic Propofol for Nausea and Vomiting During for Cesarean Section Under Subarachnoid Anesthesia. (clinicaltrials.gov) - Dec 17, 2014
P4, N=112, Completed, Sponsor: G. d'Annunzio University
Active, not recruiting --> Completed | Trial primary completion date: May 2015 --> Sep 2014 N=180 --> 112
- Clinical: Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo (clinicaltrials.gov) - Dec 17, 2014
P=N/A, N=50, Recruiting, Sponsor: Yale University
- Amitiza (lubiprostone) / Takeda, Mallinckrodt
Trial completion: The Effectiveness of Lubiprostone in Constipated Diabetics (clinicaltrials.gov) - Dec 17, 2014
P4, N=121, Completed, Sponsor: Emory University
N=180 --> 112 Recruiting --> Completed
- || Trial primary completion date: Performance, Efficacy and Safety of Vibrating Capsule in Aiding Constipated Individuals (clinicaltrials.gov) - Dec 13, 2014
P=N/A, N=144, Recruiting, Sponsor: Vibrant Ltd.
Recruiting --> Completed Trial primary completion date: Nov 2014 --> Jun 2015
- ||||| New P2 trial: Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation (clinicaltrials.gov) - Dec 11, 2014
P2, N=192, Not yet recruiting, Sponsor: KGK Synergize Inc.
- ||||| Enrollment closed, Trial primary completion date: Effect of Probiotic Formula on Reducing the Risk for Antibiotic-associated Diarrhoea (clinicaltrials.gov) - Dec 10, 2014
P2/3, N=400, Active, not recruiting, Sponsor: Danisco
Trial primary completion date: Nov 2014 --> Jun 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Dec 2014
- || Enrollment closed, Trial primary completion date: Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=184, Active, not recruiting, Sponsor: Danisco
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Dec 2014 Recruiting --> Active, not recruiting | Trial primary completion date: May 2013 --> Jan 2015
- Trial completion, Enrollment change: A Double Blind Clinical Trial of DCS for Food Anxiety (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=47, Completed, Sponsor: Washington University School of Medicine
Recruiting --> Active, not recruiting | Trial primary completion date: May 2013 --> Jan 2015 Recruiting --> Completed | N=70 --> 47
- | Trial completion: Vibrant: Safety Evaluation of the Vibrating Capsule (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=26, Completed, Sponsor: Vibrant Ltd.
Recruiting --> Completed | N=70 --> 47 Recruiting --> Completed
- Biomarker, Enrollment open, Head-to-Head: CACATU: Head-to-head Comparison of Two Fecal Biomarkers to Screen Children for IBD (clinicaltrials.gov) - Dec 9, 2014
P=N/A, N=335, Recruiting, Sponsor: University Medical Centre Groningen
Recruiting --> Completed Not yet recruiting --> Recruiting
- ondansetron / Generic mfg.
Enrollment change, Trial termination, Trial primary completion date: Ondangapi: Efficacy of Ondansetron on Vomiting Due to Acute Gastroenteritis in Pediatric During Winter (clinicaltrials.gov) - Dec 6, 2014
P3, N=20, Terminated, Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting --> Recruiting N=500 --> 20 | Recruiting --> Terminated | Trial primary completion date: Jan 2016 --> Oct 2014
- Enrollment closed: Engaging Latino Families in Eating Disorders Treatment (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=40, Active, not recruiting, Sponsor: Mae Lynn Reyes-Rodriguez, PhD
N=500 --> 20 | Recruiting --> Terminated | Trial primary completion date: Jan 2016 --> Oct 2014 Recruiting --> Active, not recruiting
- | Trial completion: Acupuncture for Patients With Function Dyspepsia (clinicaltrials.gov) - Dec 6, 2014
P3, N=200, Completed, Sponsor: Chengdu University of Traditional Chinese Medicine
Recruiting --> Active, not recruiting Recruiting --> Completed
- ||| Trial completion: Outpatient Treatment of Constipation in Children (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=239, Completed, Sponsor: Line Modin
Recruiting --> Completed Active, not recruiting --> Completed
- || Movicol (polyethylene glycol/sodium bicarbonate/sodium chloride/potassium chloride) / Mochida, Eisai, Norgine
Trial primary completion date: Maintenance Treatment for Children With Constipation (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=125, Recruiting, Sponsor: Line Modin
Active, not recruiting --> Completed Trial primary completion date: Sep 2014 --> Aug 2015
- | loperamide / Generic mfg.
Trial completion, Trial primary completion date: Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trial (clinicaltrials.gov) - Dec 6, 2014
P2/3, N=472, Completed, Sponsor: Chengdu University of Traditional Chinese Medicine
Trial primary completion date: Sep 2014 --> Aug 2015 Recruiting --> Completed | Trial primary completion date: Aug 2013 --> Feb 2014
- ||||||| Trial completion, Enrollment change: Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population (clinicaltrials.gov) - Dec 5, 2014
P3, N=290, Completed, Sponsor: Örebro University, Sweden
Recruiting --> Completed | Trial primary completion date: Aug 2013 --> Feb 2014 Enrolling by invitation --> Completed | N=400 --> 290
- | Trial completion, Trial primary completion date: Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope (clinicaltrials.gov) - Dec 5, 2014
P3, N=200, Completed, Sponsor: Faculty of Medicine, University of Alexandria
Enrolling by invitation --> Completed | N=400 --> 290 Recruiting --> Completed | Trial primary completion date: Sep 2010 --> Sep 2011
- Trial primary completion date: Cancer Anorexia and the Central Nervous System (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=3, Recruiting, Sponsor: University of Roma La Sapienza
Recruiting --> Completed | Trial primary completion date: Sep 2010 --> Sep 2011 Trial primary completion date: Jun 2013 --> Dec 2014
- oxycodone/naloxone ER / Generic mfg.
Enrollment open, Trial initiation date, Surgery: TACS: A Comparison of Targinact vs. Oxycodone on Gut Function After Colorectal Surgery (clinicaltrials.gov) - Dec 5, 2014
P3, N=50, Recruiting, Sponsor: University of Edinburgh
Trial primary completion date: Jun 2013 --> Dec 2014 Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014
- Trial primary completion date: Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea (clinicaltrials.gov) - Nov 25, 2014
P3, N=150, Recruiting, Sponsor: Sinaloa Pediatric Hospital
Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014 Trial primary completion date: Oct 2014 --> Oct 2015