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47 Companies |
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50 Products |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- Avastin (bevacizumab) / Roche
Enrollment change, Trial withdrawal, Trial primary completion date: Pilot Study of Bevacizumab (Avastin) in Patients With Septic Shock (clinicaltrials.gov) - Feb 9, 2015
P=N/A, N=0, Withdrawn, Sponsor: Beth Israel Deaconess Medical Center
N=20 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jan 2011 --> Jan 2015
- ganetespib (ADX-1612) / Aldeyra, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment change, Trial primary completion date, Combination therapy, Metastases: Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (clinicaltrials.gov) - Feb 6, 2015
P1, N=18, Recruiting, Sponsor: New York University School of Medicine
N=20 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jan 2011 --> Jan 2015 N=24 --> 18 | Trial primary completion date: Aug 2015 --> May 2016
- Trial primary completion date, IO biomarker: Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=1, Recruiting, Sponsor: Chinese PLA General Hospital
N=24 --> 18 | Trial primary completion date: Aug 2015 --> May 2016 Trial primary completion date: Jul 2013 --> Jul 2015
- remifentanil / Generic mfg., flurbiprofen / Generic mfg.
Trial completion, Enrollment change: Combination of Remifentanil and Flurbiprofen in Sedation and Analgesia for ESWL of Pancreatic Stone (clinicaltrials.gov) - Feb 5, 2015
P4, N=60, Completed, Sponsor: Changhai Hospital
Trial primary completion date: Jul 2013 --> Jul 2015 Recruiting --> Completed | N=30 --> 60
- ||| Trial completion: Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=392, Completed, Sponsor: Chulalongkorn University
Recruiting --> Completed | N=30 --> 60 Recruiting --> Completed
- Enrollment change, Trial termination: CAESAR: Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture (clinicaltrials.gov) - Feb 5, 2015
P3, N=11, Terminated, Sponsor: UMC Utrecht
Recruiting --> Completed N=70 --> 11 | Recruiting --> Terminated; Futility and limited feasibility
- Trial primary completion date: Cerebral Autoregulation in Non Neurological Critical Patients. (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=100, Recruiting, Sponsor: Althaia Xarxa Assistencial Universitària de Manresa
N=70 --> 11 | Recruiting --> Terminated; Futility and limited feasibility Trial primary completion date: Jun 2014 --> Dec 2015
- Enrollment change, Trial termination, Trial primary completion date: DOVSS: Discontinuation Order of Vasopressors in Septic Shock (clinicaltrials.gov) - Jan 30, 2015
P=N/A, N=78, Terminated, Sponsor: Samsung Medical Center
Trial primary completion date: Jun 2014 --> Dec 2015 N=134 --> 78 | Recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Dec 2013; Futility by interim analysis
- || Trial primary completion date: THORN: Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators. (clinicaltrials.gov) - Jan 29, 2015
P=N/A, N=1750, Active, not recruiting, Sponsor: Biotronik SE & Co. KG
N=134 --> 78 | Recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Dec 2013; Futility by interim analysis Trial primary completion date: Jun 2013 --> Sep 2013
- dobutamine / Generic mfg.
Biomarker, Enrollment open: Shockomics: Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock (clinicaltrials.gov) - Jan 29, 2015
P=N/A, N=115, Recruiting, Sponsor: Shockomics Consortium
Trial primary completion date: Jun 2013 --> Sep 2013 Not yet recruiting --> Recruiting
- ||| Clinical: Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya (clinicaltrials.gov) - Jan 28, 2015
P=N/A, N=440, Not yet recruiting, Sponsor: Duke University
- ganetespib (ADX-1612) / Aldeyra, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment change, Trial primary completion date, Combination therapy, Metastases: Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (clinicaltrials.gov) - Jan 28, 2015
P1, N=24, Recruiting, Sponsor: New York University School of Medicine
Not yet recruiting --> Recruiting N=18 --> 24 | Trial primary completion date: Feb 2015 --> Aug 2015
- Trial completion, Trial primary completion date: Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis) (clinicaltrials.gov) - Jan 20, 2015
P=N/A, N=64, Completed, Sponsor: University Hospital, Grenoble
N=18 --> 24 | Trial primary completion date: Feb 2015 --> Aug 2015 Recruiting --> Completed | Trial primary completion date: Jun 2013 --> Oct 2012
- Trial completion, Enrollment change: SNA&Sepsis: Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact (clinicaltrials.gov) - Jan 20, 2015
P4, N=13, Completed, Sponsor: University Hospital, Grenoble
Recruiting --> Completed | Trial primary completion date: Jun 2013 --> Oct 2012 Recruiting --> Completed | N=30 --> 13
- New P1 trial: rTSST-1 Variant Vaccine Phase 1 (clinicaltrials.gov) - Jan 17, 2015
P1, N=46, Recruiting, Sponsor: Biomedizinische Forschungs gmbH
- Trial primary completion date: EARTH-ICU: Early Physical Therapy in Patients With Sepsis (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=36, Recruiting, Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Recruiting --> Completed | N=30 --> 13 Trial primary completion date: Dec 2014 --> Jul 2015
- |||||||||| New P3 trial: Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris (clinicaltrials.gov) - Jan 15, 2015
P3, N=80, Recruiting, Sponsor: Evgeny Shkolnik, MD
- Trial completion: Relative Adrenal Insufficiency in Preterm Very Low Birth Weight Infants With Shock (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=39, Completed, Sponsor: All India Institute of Medical Sciences, New Delhi
Trial primary completion date: Dec 2014 --> Jul 2015 Recruiting --> Completed
- Clinical: ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco® LPS Adsorber (clinicaltrials.gov) - Jan 15, 2015
P=N/A, N=32, Not yet recruiting, Sponsor: Alteco Medical AB
- || New P3 trial: Balanced Salt Solution VS. Normal Saline Solution in Septic Shock (clinicaltrials.gov) - Jan 13, 2015
P3, N=60, Active, not recruiting, Sponsor: Ramathibodi Hospital
- luminespib (AUY922) / Ligand, Erbitux (cetuximab) / Eli Lilly, EMD Serono
Enrollment closed, Metastases: Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer (clinicaltrials.gov) - Jan 8, 2015
P1, N=18, Active, not recruiting, Sponsor: Swedish Medical Center
Recruiting --> Completed Recruiting --> Active, not recruiting
- || Trial primary completion date: Hyaluronan in the Treatment of Painful Achilles Tendinopathy. (clinicaltrials.gov) - Jan 5, 2015
P=N/A, N=80, Recruiting, Sponsor: TRB Chemedica AG
Recruiting --> Active, not recruiting Trial primary completion date: Apr 2015 --> Sep 2015
- Enrollment open: The Impact of Fellow-performed Cardiopulmonary Ultrasound Exams (clinicaltrials.gov) - Jan 2, 2015
P=N/A, N=250, Recruiting, Sponsor: Beth Israel Medical Center
Trial primary completion date: Apr 2015 --> Sep 2015 Not yet recruiting --> Recruiting
- Clinical: Inflammatory Response in Aortic Valve Replacement (clinicaltrials.gov) - Dec 25, 2014
P=N/A, N=100, Recruiting, Sponsor: University Hospital Inselspital, Berne
- || Trial primary completion date: IRAMST: Inflammatory Response After Muscle and Skeleton Trauma (clinicaltrials.gov) - Dec 24, 2014
P=N/A, N=90, Recruiting, Sponsor: University of Ulm
Not yet recruiting --> Recruiting Trial primary completion date: Oct 2014 --> Oct 2015
- Enrollment open: Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study (clinicaltrials.gov) - Dec 13, 2014
P=N/A, N=20, Recruiting, Sponsor: Domonkos Trásy
Trial primary completion date: Oct 2014 --> Oct 2015 Active, not recruiting --> Recruiting
- doxazosin mesylate / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Impact of Renal Anatomy on Shock Wave Lithotripsy Outcomes for Lower Pole Kidney Stones (clinicaltrials.gov) - Dec 13, 2014
P=N/A, N=100, Completed, Sponsor: University of Sao Paulo
Active, not recruiting --> Recruiting Recruiting --> Completed | N=150 --> 100 | Trial primary completion date: Dec 2015 --> Aug 2014
- Clinical: ESWT: The Effects of Extracorporeal Shock Wave Therapy in Patients With Coccydynia: A Randomized Controlled Trial (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=42, Completed, Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
- | Trial completion, Enrollment change, Trial primary completion date, Surgery: Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery (clinicaltrials.gov) - Dec 10, 2014
P=N/A, N=27, Completed, Sponsor: University of Cologne
Recruiting --> Completed | N=150 --> 100 | Trial primary completion date: Dec 2015 --> Aug 2014 Recruiting --> Completed | N=60 --> 27 | Trial primary completion date: Jan 2015 --> Sep 2014
- Trial completion, Enrollment change: Calcinosis Cutis: Therapeutic Effects of Extracorporeal Shock Wave Therapy (ESWT) (clinicaltrials.gov) - Dec 10, 2014
P3, N=4, Completed, Sponsor: University of Zurich
Recruiting --> Completed | N=60 --> 27 | Trial primary completion date: Jan 2015 --> Sep 2014 Recruiting --> Completed | N=15 --> 4
- Enrollment open: MC Monitor: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation (clinicaltrials.gov) - Dec 9, 2014
P=N/A, N=10, Recruiting, Sponsor: Advanced Perfusion Diagnostics
Recruiting --> Completed | N=15 --> 4 Not yet recruiting --> Recruiting
- || Trial primary completion date: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=361, Recruiting, Sponsor: University of British Columbia
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2014 --> Dec 2015
- Enrollment change, Trial termination: Investigate the Activity of Endotoxin in Severe Sepsis (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=2, Terminated, Sponsor: National Taiwan University Hospital
Trial primary completion date: Dec 2014 --> Dec 2015 N=60 --> 2 | Recruiting --> Terminated; The quality of Limulus Amebocyte Lysate (LAL) test was poor.
- || Enrollment closed, Trial primary completion date: ESWTvsED: Low-energy Linear Extracorporal Shock Wave Therapy for Erectile Dysfunction. (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=126, Active, not recruiting, Sponsor: Grzegorz Fojecki
N=60 --> 2 | Recruiting --> Terminated; The quality of Limulus Amebocyte Lysate (LAL) test was poor. Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2015 --> Aug 2014
- ||| Biomarker, Trial completion, Trial primary completion date: The Value of PSP in Predicting Outcome in ICU Surgical Peritonitis Patients (clinicaltrials.gov) - Dec 6, 2014
P=N/A, N=137, Completed, Sponsor: University of Magdeburg
Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2015 --> Aug 2014 Enrolling by invitation --> Completed | Trial primary completion date: Dec 2011 --> Dec 2014
- Enrollment closed: Phase I STEBVax in Healthy Adults (clinicaltrials.gov) - Dec 6, 2014
P1, N=29, Active, not recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Enrolling by invitation --> Completed | Trial primary completion date: Dec 2011 --> Dec 2014 Recruiting --> Active, not recruiting
- Trial termination: Utility of High-Fidelity Simulation In the Education and Assessment of Residents in the Recognition and Management of the Sepsis Syndrome (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=40, Terminated, Sponsor: New York University School of Medicine
Recruiting --> Active, not recruiting Not yet recruiting --> Terminated; Key Personnel left institution
- ||| Clinical: PPV to Guide Fluid Management in the PICU (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=150, Not yet recruiting, Sponsor: University of North Carolina, Chapel Hill
- Trial completion, Trial primary completion date: Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=46, Completed, Sponsor: University of Michigan
Not yet recruiting --> Terminated; Key Personnel left institution Recruiting --> Completed | Trial primary completion date: Mar 2014 --> Nov 2014
- Biomarker, Trial completion, Enrollment change: H2S-1: Hydrogen Sulfide as Prognostic Factor (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=50, Completed, Sponsor: University Medical Centre Ljubljana
Recruiting --> Completed | Trial primary completion date: Mar 2014 --> Nov 2014 Recruiting --> Completed | N=150 --> 50
- Enrollment open, Trial initiation date: AVATAR: Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention (clinicaltrials.gov) - Dec 5, 2014
P4, N=40, Recruiting, Sponsor: Ottawa Heart Institute Research Corporation
Recruiting --> Completed | N=150 --> 50 Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014
- Clinical: OFTaPLR: Optimization of Fluid Therapy in Sepsis by a Passive Leg Raising Test (clinicaltrials.gov) - Nov 28, 2014
P=N/A, N=120, Recruiting, Sponsor: Karolinska Institutet
- Trial completion: Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals. (clinicaltrials.gov) - Nov 25, 2014
P=N/A, N=10, Completed, Sponsor: University of Aarhus
Not yet recruiting --> Recruiting | Initiation date: Jun 2014 --> Oct 2014 Active, not recruiting --> Completed
- paracetamol / Generic mfg.
Enrollment open: Radial Shock Wave and Acupuncture for Myofascial Pain (clinicaltrials.gov) - Nov 24, 2014
P=N/A, N=80, Recruiting, Sponsor: Shin Kong Wu Ho-Su Memorial Hospital
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- || Enrollment closed: ReduceIT: Reduction of Inappropriate Shocks of Implantable Cardioverter Defibrillators (ICDs) With Enhanced SVT Discriminators (clinicaltrials.gov) - Nov 24, 2014
P=N/A, N=730, Active, not recruiting, Sponsor: St. Jude Medical
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion, Enrollment change: Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults (clinicaltrials.gov) - Nov 24, 2014
P=N/A, N=57, Completed, Sponsor: Denver Health and Hospital Authority
Recruiting --> Active, not recruiting Recruiting --> Completed | N=136 --> 57
- Trial termination, Trial primary completion date: Hyper2S: Hyperoxia and Hypertonic Saline in Septic Shock (clinicaltrials.gov) - Nov 20, 2014
P=N/A, N=441, Terminated, Sponsor: University Hospital, Angers
Recruiting --> Completed | N=136 --> 57 Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Sep 2014
- || Trial primary completion date: Narrow Versus Wide Focal Zones for Shock Wave Lithotripsy of Renal Calculi (clinicaltrials.gov) - Nov 19, 2014
P=N/A, N=300, Recruiting, Sponsor: St. Michael's Hospital, Toronto
Active, not recruiting --> Terminated | Trial primary completion date: Jun 2014 --> Sep 2014 Trial primary completion date: Apr 2014 --> Jun 2015
- tranexamic acid oral / Generic mfg.
Trial completion, Enrollment change: Single Dose Enteral Tranexamic Acid in Critically Ill Patients (clinicaltrials.gov) - Nov 19, 2014
P2, N=4, Completed, Sponsor: San Diego Veterans Healthcare System
Trial primary completion date: Apr 2014 --> Jun 2015 Recruiting --> Completed | N=200 --> 4
- Biomarker, Trial primary completion date: Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis? (clinicaltrials.gov) - Nov 18, 2014
P=N/A, N=40, Recruiting, Sponsor: Sygehus Lillebaelt
Recruiting --> Completed | N=200 --> 4 Trial primary completion date: Jul 2014 --> Jun 2015