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47 Companies |
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50 Products |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- Trial completion, Enrollment change, IO biomarker, Surgery: IRAS: Inflammatory Response During Anesthesia and Surgery (clinicaltrials.gov) - Jun 24, 2015
P=N/A, N=120, Completed, Sponsor: UMC Utrecht
Active, not recruiting --> Completed | N=240 --> 120
- Trial primary completion date: MC Monitor: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation (clinicaltrials.gov) - Jun 23, 2015
P=N/A, N=10, Recruiting, Sponsor: Advanced Perfusion Diagnostics
Active, not recruiting --> Completed | N=240 --> 120 Trial primary completion date: Apr 2015 --> Mar 2016
- Enrollment open, Trial primary completion date: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - Jun 18, 2015
P1, N=88, Recruiting, Sponsor: Dr. Hasan Alam
Trial primary completion date: Apr 2015 --> Mar 2016 Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2015 --> Dec 2015
- Enrollment open: Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock (clinicaltrials.gov) - Jun 17, 2015
P1/2, N=40, Recruiting, Sponsor: St. Michael's Hospital, Toronto
Active, not recruiting --> Recruiting | Trial primary completion date: Sep 2015 --> Dec 2015 Not yet recruiting --> Recruiting
- ||| Enrollment open: PPV to Guide Fluid Management in the PICU (clinicaltrials.gov) - Jun 16, 2015
P=N/A, N=150, Enrolling by invitation, Sponsor: University of North Carolina, Chapel Hill
Not yet recruiting --> Recruiting Not yet recruiting --> Enrolling by invitation
- Trial completion: Phase I STEBVax in Healthy Adults (clinicaltrials.gov) - Jun 15, 2015
P1, N=29, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Enrolling by invitation Active, not recruiting --> Completed
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock (clinicaltrials.gov) - Jun 11, 2015
P4, N=80, Recruiting, Sponsor: Srinakharinwirot University
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Jun 2016
- || Trial primary completion date: Narrow Versus Wide Focal Zones for Shock Wave Lithotripsy of Renal Calculi (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=300, Recruiting, Sponsor: St. Michael's Hospital, Toronto
Trial primary completion date: Dec 2015 --> Jun 2016 Trial primary completion date: Jun 2015 --> Jun 2016
- Trial primary completion date: Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury (clinicaltrials.gov) - Jun 11, 2015
P1, N=20, Recruiting, Sponsor: Denver Health and Hospital Authority
Trial primary completion date: Jun 2015 --> Jun 2016 Trial primary completion date: May 2015 --> May 2016
- Trial completion: Implantation Rate of Vitrified-warmed Collapsed Blastocysts (clinicaltrials.gov) - Jun 9, 2015
P=N/A, N=270, Completed, Sponsor: Centre for Reproductive Medicine, Belgium
Trial primary completion date: May 2015 --> May 2016 Recruiting --> Completed
- | luminespib (AUY922) / Ligand, Erbitux (cetuximab) / Eli Lilly, EMD Serono
Trial completion, Trial primary completion date, Metastases: Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer (clinicaltrials.gov) - Jun 6, 2015
P1, N=20, Completed, Sponsor: Swedish Medical Center
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> May 2015
- | Trial completion, Enrollment change: Extracorporeal Shock Wave Treatment - Can the Pain be Reduced? (clinicaltrials.gov) - Jun 3, 2015
P4, N=36, Completed, Sponsor: University of Zurich
Active, not recruiting --> Completed | Trial primary completion date: Jan 2015 --> May 2015 Recruiting --> Completed | N=100 --> 36
- Trial completion, Enrollment change: MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 (clinicaltrials.gov) - May 27, 2015
P=N/A, N=70, Completed, Sponsor: Rigshospitalet, Denmark
Recruiting --> Completed | N=100 --> 36 Recruiting --> Completed | N=50 --> 70
- Trial completion: Effect of Different Strategies for Titrating a High MAP on Microcirculation (clinicaltrials.gov) - May 27, 2015
P4, N=20, Completed, Sponsor: Southeast University, China
Recruiting --> Completed | N=50 --> 70 Recruiting --> Completed
- Trial completion, Enrollment change: PtcO2-FR: Fluid Responsiveness Predicted by PtcO2 in Critically Ill Patients (clinicaltrials.gov) - May 27, 2015
P=N/A, N=19, Completed, Sponsor: Southeast University, China
Recruiting --> Completed Recruiting --> Completed | N=30 --> 19
- Enrollment change, Trial termination, Trial primary completion date: High Dose Vitamin C in the Critically Ill Patient (clinicaltrials.gov) - May 22, 2015
P2, N=8, Terminated, Sponsor: Rutgers, The State University of New Jersey
Recruiting --> Completed | N=30 --> 19 N=60 --> 8 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Feb 2014; PI's additional responsibilities and time commitments prevent him from completing this clinical trial so he decided to close the study prematurely
- dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine on Microcirculation in Septic Shock (clinicaltrials.gov) - May 22, 2015
P4, N=26, Completed, Sponsor: Southeast University, China
N=60 --> 8 | Active, not recruiting --> Terminated | Trial primary completion date: Mar 2016 --> Feb 2014; PI's additional responsibilities and time commitments prevent him from completing this clinical trial so he decided to close the study prematurely Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Apr 2015
- Enrollment open, Trial initiation date, Trial primary completion date: Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study (clinicaltrials.gov) - May 20, 2015
P=N/A, N=40, Recruiting, Sponsor: Karl-Andre Wian
Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Apr 2015 Not yet recruiting --> Recruiting | Initiation date: Sep 2014 --> Feb 2015 | Trial primary completion date: Sep 2015 --> Mar 2016
- Enrollment closed, Trial primary completion date: Evaluation of an Absorbable Implant for the Treatment of Nasal Valve Collapse (clinicaltrials.gov) - May 20, 2015
P=N/A, N=30, Active, not recruiting, Sponsor: Spirox, Inc.
Not yet recruiting --> Recruiting | Initiation date: Sep 2014 --> Feb 2015 | Trial primary completion date: Sep 2015 --> Mar 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Aug 2015
- | Enrollment closed, Trial primary completion date: VANCS II: Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients (clinicaltrials.gov) - May 20, 2015
P3, N=250, Active, not recruiting, Sponsor: Instituto do Cancer do Estado de S
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Aug 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2013 --> Mar 2014
- ampreloxetine (TD-9855) / Theravance Biopharma
Phase classification: Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction. (clinicaltrials.gov) - May 13, 2015
P1, N=6, Completed, Sponsor: Theravance Biopharma R & D, Inc.
Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2013 --> Mar 2014 Phase classification: P4 --> P1
- Enrollment closed: Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis (clinicaltrials.gov) - May 12, 2015
P=N/A, N=1, Active, not recruiting, Sponsor: Chinese PLA General Hospital
Phase classification: P4 --> P1 Recruiting --> Active, not recruiting
- |||| apatorsen (OGX-427) / Achieve Life Sciences
Trial completion, Metastases: OGX-427 in Castration Resistant Prostate Cancer Patients (clinicaltrials.gov) - May 6, 2015
P2, N=74, Completed, Sponsor: British Columbia Cancer Agency
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- azithromycin / Generic mfg.
Trial termination, IO biomarker, Immunomodulating: Efficacy of Macrolide Immunomodulation in Severe Sepsis. (clinicaltrials.gov) - May 5, 2015
P2, N=100, Terminated, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Suspended --> Terminated; Safety evaluation due to recent publications.
- Trial completion, Trial primary completion date: Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome (clinicaltrials.gov) - May 4, 2015
P1/2, N=350, Completed, Sponsor: Jinhua Central Hospital
Suspended --> Terminated; Safety evaluation due to recent publications. Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Jun 2014
- Enrollment closed: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - Apr 30, 2015
P1, N=88, Active, not recruiting, Sponsor: Dr. Hasan Alam
Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Jun 2014 Recruiting --> Active, not recruiting
- Trial primary completion date: NASA: Role of Neutrophil Activation in Anaphylaxis to Neuro-Muscular Blocking Agents (clinicaltrials.gov) - Apr 25, 2015
P=N/A, N=200, Recruiting, Sponsor: Assistance Publique - H
Recruiting --> Active, not recruiting Trial primary completion date: Jul 2014 --> Jul 2015
- Biomarker, Trial completion, Enrollment change: Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis? (clinicaltrials.gov) - Apr 21, 2015
P=N/A, N=21, Completed, Sponsor: Sygehus Lillebaelt
Trial primary completion date: Jul 2014 --> Jul 2015 Recruiting --> Completed | N=40 --> 21
- ||| hydrocortisone / Generic mfg.
Trial completion: Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Apr 20, 2015
P=N/A, N=197, Completed, Sponsor: Mahidol University
Recruiting --> Completed | N=40 --> 21 Recruiting --> Completed
- || dexmedetomidine / Generic mfg.
Surgery: Study of Dexmedetomidine in Spine Surgery (clinicaltrials.gov) - Apr 19, 2015
P4, N=250, Recruiting, Sponsor: University of Virginia
Recruiting --> Completed Trial primary completion date: Dec 2014 --> Dec 2016
- ||| Enrollment change, Gram negative: GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults (clinicaltrials.gov) - Apr 15, 2015
P2, N=1415, Completed, Sponsor: GlaxoSmithKline
Trial primary completion date: Dec 2014 --> Dec 2016 N=1890 --> 1415
- Trial completion, Enrollment change, Trial primary completion date: OVATION: Optimal VAsopressor titraTION Pilot Randomized Controlled Trial (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=120, Completed, Sponsor: Francois Lamontagne
N=1890 --> 1415 Recruiting --> Completed | N=80 --> 120 | Trial primary completion date: Apr 2015 --> Dec 2014
- Trial primary completion date: Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) (clinicaltrials.gov) - Apr 15, 2015
P3, N=1500, Enrolling by invitation, Sponsor: Lawson Health Research Institute
Recruiting --> Completed | N=80 --> 120 | Trial primary completion date: Apr 2015 --> Dec 2014 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial primary completion date: FLOVAC: FLOTRAC/VIGILEO in Acute Circulatory Failure (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=50, Recruiting, Sponsor: Hôpital Européen Marseille
Trial primary completion date: Dec 2015 --> Dec 2016 Trial primary completion date: Mar 2015 --> Apr 2016
- Leukine (sargramostim) / Partner Therap
Trial primary completion date, Metastases: Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=23, Active, not recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Mar 2015 --> Apr 2016 Trial primary completion date: Sep 2014 --> Sep 2015
- Trial initiation date, Trial primary completion date: Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock (clinicaltrials.gov) - Apr 14, 2015
P1/2, N=40, Not yet recruiting, Sponsor: St. Michael's Hospital, Toronto
Trial primary completion date: Sep 2014 --> Sep 2015 Initiation date: Sep 2014 --> May 2015 | Trial primary completion date: Sep 2016 --> May 2017
- |||| Trial completion, Gram negative: GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults (clinicaltrials.gov) - Apr 13, 2015
P2, N=1415, Completed, Sponsor: GlaxoSmithKline
Initiation date: Sep 2014 --> May 2015 | Trial primary completion date: Sep 2016 --> May 2017 Terminated --> Completed
- Trial completion: The AVERT Sepsis Investigation (clinicaltrials.gov) - Apr 6, 2015
P=N/A, N=100, Completed, Sponsor: Christiana Care Health Services
Terminated --> Completed Recruiting --> Completed
- Trial completion, Trial initiation date, Monotherapy, Head-to-Head: Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit (clinicaltrials.gov) - Mar 31, 2015
P=N/A, N=84, Completed, Sponsor: Institute of Liver and Biliary Sciences, India
Recruiting --> Completed Recruiting --> Completed | Initiation date: Apr 2013 --> Oct 2012
- | Enrollment open, Enrollment change, Trial primary completion date: IoxRea: Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study (clinicaltrials.gov) - Mar 24, 2015
P3, N=100, Recruiting, Sponsor: University Hospital, Tours
Recruiting --> Completed | Initiation date: Apr 2013 --> Oct 2012 Not yet recruiting --> Recruiting | N=20 --> 100 | Trial primary completion date: Aug 2014 --> Aug 2016
- Trial completion: Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Mar 19, 2015
P=N/A, N=30, Completed, Sponsor: Policlinico Hospital
Not yet recruiting --> Recruiting | N=20 --> 100 | Trial primary completion date: Aug 2014 --> Aug 2016 Recruiting --> Completed
- ||| Trial completion: Procalcitonin Monitoring Sepsis Study (clinicaltrials.gov) - Mar 17, 2015
P=N/A, N=858, Completed, Sponsor: Brahms AG
Recruiting --> Completed Recruiting --> Completed
- Trial completion, Surgery: Effect of TEAS on the Incidence Rate of SIRS in Patients Undergoing Abdominal Surgery (clinicaltrials.gov) - Mar 7, 2015
P=N/A, N=105, Completed, Sponsor: Fourth Military Medical University
Recruiting --> Completed Recruiting --> Completed
- | Trial completion, Enrollment change: Comparison of Compensatory Reserve Index to Intravascular Volume Change and Stroke Volume (clinicaltrials.gov) - Mar 7, 2015
P=N/A, N=42, Completed, Sponsor: Flashback Technologies
Recruiting --> Completed Not yet recruiting --> Completed | N=100 --> 42
- | Enrollment open: PUPTH: Pre-Hospital Use of Plasma for Traumatic Hemorrhage (clinicaltrials.gov) - Mar 5, 2015
P2/3, N=210, Recruiting, Sponsor: Virginia Commonwealth University
Not yet recruiting --> Completed | N=100 --> 42 Active, not recruiting --> Recruiting
- || Trial primary completion date: ISIS-ICD: Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination (clinicaltrials.gov) - Feb 26, 2015
P4, N=1013, Active, not recruiting, Sponsor: Sorin Group
Active, not recruiting --> Recruiting Trial primary completion date: Oct 2016 --> Jun 2015
- Enrollment open: SEPP1B: Correlation Between PTP1B Expression and Organ Failure During Sepsis (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=54, Recruiting, Sponsor: University Hospital, Rouen
Trial primary completion date: Oct 2016 --> Jun 2015 Not yet recruiting --> Recruiting
- hydrocortisone / Generic mfg.
Trial completion: Low-dose Hydrocortisone in Acutely Burned Patients (clinicaltrials.gov) - Feb 12, 2015
P4, N=40, Completed, Sponsor: Hospices Civils de Lyon
Not yet recruiting --> Recruiting Recruiting --> Completed
- ||| Enrollment open: Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE) (clinicaltrials.gov) - Feb 11, 2015
P=N/A, N=12000, Recruiting, Sponsor: Mayo Clinic
Recruiting --> Completed Active, not recruiting --> Recruiting
- || Enrollment change, Trial primary completion date: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Feb 10, 2015
P=N/A, N=15000, Recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Recruiting N=5000 --> 15000 | Trial primary completion date: Jun 2015 --> Dec 2016