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47 Companies |
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50 Products |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- Trial primary completion date: Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study (clinicaltrials.gov) - Apr 15, 2016
P=N/A, N=40, Recruiting, Sponsor: Karl-Andre Wian
Trial primary completion date: Mar 2016 --> Jan 2017
- dobutamine / Generic mfg.
Biomarker, Enrollment closed, Trial primary completion date: Shockomics: Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock (clinicaltrials.gov) - Apr 15, 2016
P=N/A, N=115, Active, not recruiting, Sponsor: Shockomics Consortium
Trial primary completion date: Mar 2016 --> Jan 2017 Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jun 2016
- Trial completion, Enrollment change: Effects of Early Exercise Rehabilitation on Long-term Functional Recovery in Patients With Severe Sepsis (clinicaltrials.gov) - Apr 14, 2016
P=N/A, N=40, Completed, Sponsor: Yonsei University
Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2016 --> Jun 2016 Recruiting --> Completed | N=220 --> 40
- ||| eleclazine (GS-6615) / Gilead
Enrollment closed: TEMPO: Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator (clinicaltrials.gov) - Apr 8, 2016
P2, N=313, Active, not recruiting, Sponsor: Gilead Sciences
Recruiting --> Completed | N=220 --> 40 Recruiting --> Active, not recruiting
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion, Enrollment change: STRIPES: Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study (clinicaltrials.gov) - Apr 7, 2016
P4, N=57, Completed, Sponsor: Children's Hospital of Eastern Ontario
Recruiting --> Active, not recruiting Recruiting --> Completed | N=72 --> 57
- Trial primary completion date: ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco (clinicaltrials.gov) - Apr 6, 2016
P=N/A, N=32, Recruiting, Sponsor: Alteco Medical AB
Recruiting --> Completed | N=72 --> 57 Trial primary completion date: Sep 2016 --> Apr 2017
- Trial primary completion date: MC Monitor: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation (clinicaltrials.gov) - Apr 4, 2016
P=N/A, N=10, Recruiting, Sponsor: Advanced Perfusion Diagnostics
Trial primary completion date: Sep 2016 --> Apr 2017 Trial primary completion date: Mar 2016 --> Sep 2016
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: ADRENAL: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (clinicaltrials.gov) - Mar 25, 2016
P4, N=3800, Recruiting, Sponsor: The George Institute
Trial primary completion date: Mar 2016 --> Sep 2016 Trial primary completion date: Jun 2016 --> Dec 2016
- Trial completion, Enrollment change: Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea (clinicaltrials.gov) - Mar 24, 2016
P=N/A, N=1, Completed, Sponsor: National Jewish Health
Trial primary completion date: Jun 2016 --> Dec 2016 Recruiting --> Completed | N=40 --> 1
- cyclosporin A microemulsion / Generic mfg.
Enrollment change, Trial withdrawal: CLOTILDE: Cyclosporine in Acute Myocardial Infarction Complicated by Cardiogenic Shock (clinicaltrials.gov) - Mar 17, 2016
P2, N=0, Withdrawn, Sponsor: Hospices Civils de Lyon
Recruiting --> Completed | N=40 --> 1 N=100 --> 0 | Not yet recruiting --> Withdrawn
- |||| Trial primary completion date: Efficacy of Extracorporeal Shockwave Myocardial Revascularization Therapy in Patients With Stable Angina Pectoris (clinicaltrials.gov) - Mar 16, 2016
P3, N=80, Recruiting, Sponsor: Evgeny Shkolnik, MD
N=100 --> 0 | Not yet recruiting --> Withdrawn Trial primary completion date: Jan 2016 --> Jun 2016
- Trial primary completion date: The Cooling And Surviving Septic Shock Study (CASS) (clinicaltrials.gov) - Mar 9, 2016
P2/3, N=560, Recruiting, Sponsor: Danish Procalcitonin Study Group
Trial primary completion date: Jan 2016 --> Jun 2016 Trial primary completion date: Dec 2016 --> Oct 2017
- | Trial completion, Enrollment change, Trial primary completion date: CVPCHI: Central Venous Pressure Change With Volume Challenge in Patients With Hemodynamic Instability (clinicaltrials.gov) - Mar 9, 2016
P3, N=70, Completed, Sponsor: University of Monastir
Trial primary completion date: Dec 2016 --> Oct 2017 Recruiting --> Completed | N=100 --> 70 | Trial primary completion date: Nov 2012 --> Nov 2013
- Enrollment change, Trial withdrawal: SEREAL: Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients (clinicaltrials.gov) - Mar 5, 2016
P2, N=0, Withdrawn, Sponsor: Gil Joon Suh
Recruiting --> Completed | N=100 --> 70 | Trial primary completion date: Nov 2012 --> Nov 2013 N=294 --> 0 | Not yet recruiting --> Withdrawn
- Enrollment change, Trial termination: Preemptive Resuscitation for Eradication of Septic Shock (clinicaltrials.gov) - Mar 5, 2016
P=N/A, N=43, Terminated, Sponsor: Christiana Care Health Services
N=294 --> 0 | Not yet recruiting --> Withdrawn N=140 --> 43 | Active, not recruiting --> Terminated
- ||| WRAIR GSK TDEN vaccine / GSK, U.S. Army Medical Research and Development Command
Trial initiation date: A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children (clinicaltrials.gov) - Mar 1, 2016
P2, N=636, Completed, Sponsor: U.S. Army Medical Research and Materiel Command
N=140 --> 43 | Active, not recruiting --> Terminated Initiation date: Apr 2007 --> Jul 2007
- Trial primary completion date: Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness (clinicaltrials.gov) - Feb 29, 2016
P=N/A, N=30, Recruiting, Sponsor: Hopital Louis Pradel
Initiation date: Apr 2007 --> Jul 2007 Trial primary completion date: Jan 2015 --> Jul 2016
- ||||||| pyridoxalated haemoglobin polyethylene (VTR-PHP) / Curacyte
Trial completion: Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS) (clinicaltrials.gov) - Feb 27, 2016
P3, N=1000, Completed, Sponsor: Apex Bioscience
Trial primary completion date: Jan 2015 --> Jul 2016 No longer recruiting --> Completed
- | Trial completion: Shock Trial: Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock. (clinicaltrials.gov) - Feb 27, 2016
P3, N=0, Completed, Sponsor: New England Research Institutes
No longer recruiting --> Completed No longer recruiting --> Completed
- Trial primary completion date: Lung and Systemic Inflammation in the Critically Ill Patient (clinicaltrials.gov) - Feb 25, 2016
P=N/A, N=18, Recruiting, Sponsor: Rigshospitalet, Denmark
No longer recruiting --> Completed Trial primary completion date: Jul 2014 --> Nov 2016
- | Glypressin (terlipressin) / Ferring
Trial completion, Trial primary completion date: Terlipressin in Septic Shock in Cirrhosis (clinicaltrials.gov) - Feb 25, 2016
P2/3, N=72, Completed, Sponsor: Hospital Clinic of Barcelona
Trial primary completion date: Jul 2014 --> Nov 2016 Recruiting --> Completed | Trial primary completion date: Oct 2009 --> Dec 2012
- Trial primary completion date: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - Feb 24, 2016
P1, N=88, Recruiting, Sponsor: Dr. Hasan Alam
Recruiting --> Completed | Trial primary completion date: Oct 2009 --> Dec 2012 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial suspension: FLOVAC: FLOTRAC/VIGILEO in Acute Circulatory Failure (clinicaltrials.gov) - Feb 24, 2016
P=N/A, N=50, Suspended, Sponsor: Hôpital Européen Marseille
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Suspended
- Enrollment change, Trial withdrawal, Trial primary completion date: PUPTH: Pre-Hospital Use of Plasma for Traumatic Hemorrhage (clinicaltrials.gov) - Feb 23, 2016
P2/3, N=0, Withdrawn, Sponsor: Virginia Commonwealth University
Recruiting --> Suspended N=210 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Jan 2016
- Trial primary completion date: Avascular Necrosis (AVN) Long-Term Follow-up (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=35, Terminated, Sponsor: Zimmer, Inc.
N=210 --> 0 | Recruiting --> Withdrawn | Trial primary completion date: Dec 2016 --> Jan 2016 Trial primary completion date: Dec 2011 --> Feb 2013
- Biomarker, Trial completion, Enrollment change, IO biomarker: BIONEC: Biomarkers in Patients With Flesh-eating Bacterial Infections (clinicaltrials.gov) - Feb 17, 2016
P=N/A, N=169, Completed, Sponsor: Ole Hyldegaard
Trial primary completion date: Dec 2011 --> Feb 2013 Recruiting --> Completed | N=114 --> 169
- Enrollment change, Trial termination, Trial primary completion date: OFTaPLR: Optimization of Fluid Therapy in Sepsis by a Passive Leg Raising Test (clinicaltrials.gov) - Feb 9, 2016
P=N/A, N=34, Terminated, Sponsor: Karolinska Institutet
Recruiting --> Completed | N=114 --> 169 N=120 --> 34 | Recruiting --> Terminated | Trial primary completion date: Apr 2017 --> Feb 2016; The study was stopped because of futility due to unexpected low weight gain in both groups.
- Enrollment change, Trial termination, Trial primary completion date: Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) (clinicaltrials.gov) - Feb 9, 2016
P3, N=360, Terminated, Sponsor: Lawson Health Research Institute
N=120 --> 34 | Recruiting --> Terminated | Trial primary completion date: Apr 2017 --> Feb 2016; The study was stopped because of futility due to unexpected low weight gain in both groups. N=1500 --> 360 | Enrolling by invitation --> Terminated | Trial primary completion date: Dec 2016 --> Dec 2015; Due to the low recruitment rate and the large number lost to follow-up
- paracetamol / Generic mfg.
Trial completion: Radial Shock Wave and Acupuncture for Myofascial Pain (clinicaltrials.gov) - Feb 4, 2016
P=N/A, N=68, Completed, Sponsor: Shin Kong Wu Ho-Su Memorial Hospital
N=1500 --> 360 | Enrolling by invitation --> Terminated | Trial primary completion date: Dec 2016 --> Dec 2015; Due to the low recruitment rate and the large number lost to follow-up Recruiting --> Completed
- Trial primary completion date: The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome (clinicaltrials.gov) - Feb 2, 2016
P=N/A, N=50, Recruiting, Sponsor: Tri-Service General Hospital
Recruiting --> Completed Trial primary completion date: Dec 2015 --> May 2016
- Trial completion: Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers (clinicaltrials.gov) - Jan 30, 2016
P0, N=23, Completed, Sponsor: Rigshospitalet, Denmark
Trial primary completion date: Dec 2015 --> May 2016 Active, not recruiting --> Completed
- Trial completion: Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis (clinicaltrials.gov) - Jan 28, 2016
P=N/A, N=1, Completed, Sponsor: Chinese PLA General Hospital
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, IO biomarker: Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients (clinicaltrials.gov) - Jan 28, 2016
P=N/A, N=1, Completed, Sponsor: Chinese PLA General Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, Trial primary completion date: FC-Rev: Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in Septic Shock? (clinicaltrials.gov) - Jan 21, 2016
P=N/A, N=145, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: May 2016 --> Jan 2016
- Trial completion: NASA: Role of Neutrophil Activation in Anaphylaxis to Neuro-Muscular Blocking Agents (clinicaltrials.gov) - Jan 20, 2016
P=N/A, N=200, Completed, Sponsor: Assistance Publique - H
Recruiting --> Completed | Trial primary completion date: May 2016 --> Jan 2016 Recruiting --> Completed
- Enrollment change, Trial termination: Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT) (clinicaltrials.gov) - Jan 16, 2016
P=N/A, N=22, Terminated, Sponsor: Washington University School of Medicine
Recruiting --> Completed N=125 --> 22 | Recruiting --> Terminated; lack of resources
- ||| Trial completion, Enrollment change: SAPS: Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) (clinicaltrials.gov) - Jan 7, 2016
P=N/A, N=1575, Completed, Sponsor: VU University Medical Center
N=125 --> 22 | Recruiting --> Terminated; lack of resources Active, not recruiting --> Completed | N=2246 --> 1575
- Trial primary completion date: Cerebral Autoregulation in Non Neurological Critical Patients. (clinicaltrials.gov) - Dec 30, 2015
P=N/A, N=100, Recruiting, Sponsor: Althaia Xarxa Assistencial Universitària de Manresa
Active, not recruiting --> Completed | N=2246 --> 1575 Trial primary completion date: Dec 2015 --> Dec 2016
- Trial completion, Trial primary completion date: MUSCLE: Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation (clinicaltrials.gov) - Dec 19, 2015
P=N/A, N=63, Completed, Sponsor: University College, London
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Feb 2018 --> Dec 2015
- Trial completion, Enrollment change: IRAMST: Inflammatory Response After Muscle and Skeleton Trauma (clinicaltrials.gov) - Dec 18, 2015
P=N/A, N=48, Completed, Sponsor: University of Ulm
Recruiting --> Completed | Trial primary completion date: Feb 2018 --> Dec 2015 Recruiting --> Completed | N=90 --> 48
- HSP Gp96 vaccine / Cure & Sure Biotech
Enrollment closed, Trial primary completion date: Research for Immunotherapy of Glioblastoma With Autologous Heat Shock Protein gp96 (clinicaltrials.gov) - Dec 11, 2015
P1, N=20, Active, not recruiting, Sponsor: Cure&Sure Biotech Co., LTD
Recruiting --> Completed | N=90 --> 48 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Jul 2015
- Trial withdrawal: A Pilot Study to Evaluate the Systemic Inflammatory Response of Thoracoabdominal Aortic Aneurysm Repair. (clinicaltrials.gov) - Dec 7, 2015
P=N/A, N=0, Withdrawn, Sponsor: The University of Texas Health Science Center, Houston
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2014 --> Jul 2015 Terminated --> Withdrawn
- Trial completion: Echocardiographic Prediction of Fluid Responsiveness After a Mini-fluid Challenge in Non-ventilated Patients With Shock (clinicaltrials.gov) - Dec 6, 2015
P=N/A, N=71, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
Terminated --> Withdrawn Recruiting --> Completed
- Trial completion, Trial primary completion date: Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock. (clinicaltrials.gov) - Dec 5, 2015
P2, N=60, Completed, Sponsor: University of Roma La Sapienza
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Feb 2015
- Trial primary completion date: CULPRIT-SHOCK: Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (clinicaltrials.gov) - Dec 5, 2015
P4, N=706, Recruiting, Sponsor: University of Luebeck
Recruiting --> Completed | Trial primary completion date: Sep 2014 --> Feb 2015 Trial primary completion date: Aug 2016 --> Dec 2016
- Trial completion, Trial primary completion date: CLASSIC: Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (clinicaltrials.gov) - Dec 4, 2015
P4, N=153, Completed, Sponsor: Anders Perner
Trial primary completion date: Aug 2016 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Nov 2015
- Trial primary completion date: PPV to Guide Fluid Management in the PICU (clinicaltrials.gov) - Dec 4, 2015
P=N/A, N=150, Enrolling by invitation, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Nov 2015 Trial primary completion date: Feb 2016 --> May 2016
- dobutamine / Generic mfg.
Biomarker, Trial primary completion date: Shockomics: Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock (clinicaltrials.gov) - Nov 30, 2015
P=N/A, N=115, Recruiting, Sponsor: Shockomics Consortium
Trial primary completion date: Feb 2016 --> May 2016 Trial primary completion date: Jul 2015 --> Mar 2016
- Trial primary completion date: Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study (clinicaltrials.gov) - Nov 24, 2015
P=N/A, N=20, Recruiting, Sponsor: Domonkos Trásy
Trial primary completion date: Jul 2015 --> Mar 2016 Trial primary completion date: Oct 2015 --> Dec 2016
- ||| Gohibic (vilobelimab) / Staidson Biopharma, InflaRx
Enrollment closed, Trial primary completion date: SCIENS: Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction (clinicaltrials.gov) - Nov 22, 2015
P2, N=72, Active, not recruiting, Sponsor: InflaRx GmbH
Trial primary completion date: Oct 2015 --> Dec 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2015 --> Dec 2015