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47 Companies |
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50 Products |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- Enrollment change, Trial termination: Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study (clinicaltrials.gov) - Dec 14, 2016
P=N/A, N=15, Terminated, Sponsor: Karl-Andre Wian
N=40 --> 15 | Recruiting --> Terminated; Too slow recruitment.
- Enrollment closed, Enrollment change: Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya (clinicaltrials.gov) - Dec 2, 2016
P=N/A, N=198, Active, not recruiting, Sponsor: Duke University
N=40 --> 15 | Recruiting --> Terminated; Too slow recruitment. Recruiting --> Active, not recruiting | N=440 --> 198
- Trial completion, Enrollment change: Intramedullary Femoral Reaming, Human Study (clinicaltrials.gov) - Dec 1, 2016
P=N/A, N=17, Completed, Sponsor: Ullevaal University Hospital
Recruiting --> Active, not recruiting | N=440 --> 198 Active, not recruiting --> Completed | N=36 --> 17
- |||| Trial completion: ISIS-ICD: Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination (clinicaltrials.gov) - Nov 30, 2016
P4, N=1013, Completed, Sponsor: LivaNova
Active, not recruiting --> Completed | N=36 --> 17 Active, not recruiting --> Completed
- Enrollment change, Trial termination, Trial primary completion date: The Cooling And Surviving Septic Shock Study (CASS) (clinicaltrials.gov) - Nov 23, 2016
P2/3, N=433, Terminated, Sponsor: Danish Procalcitonin Study Group
Active, not recruiting --> Completed N=560 --> 433 | Recruiting --> Terminated | Trial primary completion date: Oct 2017 --> Nov 2016; Futility
- |||| eleclazine (GS-6615) / Gilead
Trial completion: TEMPO: Evaluating Ventricular Arrhythmia in Subjects With Implantable Cardioverter Defibrillator or Cardiac Resynchronization Therapy-Defibrillator (clinicaltrials.gov) - Nov 7, 2016
P2, N=313, Completed, Sponsor: Gilead Sciences
N=560 --> 433 | Recruiting --> Terminated | Trial primary completion date: Oct 2017 --> Nov 2016; Futility Active, not recruiting --> Completed
- || Trial primary completion date: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - Nov 4, 2016
P=N/A, N=361, Recruiting, Sponsor: University of British Columbia
Active, not recruiting --> Completed Trial primary completion date: Jun 2017 --> Jun 2018
- Enrollment closed, Trial primary completion date: Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE) (clinicaltrials.gov) - Nov 2, 2016
P=N/A, N=12000, Active, not recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Jun 2017 --> Jun 2018 Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Dec 2016
- thalidomide / Generic mfg.
Enrollment change: The Effect of Thalidomide in Suppression of the Systemic Inflammatory Response Syndrome in Hemodialysis Patients (clinicaltrials.gov) - Oct 28, 2016
P3, N=16, Terminated, Sponsor: University of California, Davis
Recruiting --> Active, not recruiting | Trial primary completion date: Jun 2016 --> Dec 2016 N=11 --> 16
- || Enrollment closed, Enrollment change, Trial primary completion date: VENUS: Septic Gene Expression Using SeptiCyte (clinicaltrials.gov) - Oct 26, 2016
P=N/A, N=360, Active, not recruiting, Sponsor: Immunexpress
N=11 --> 16 Recruiting --> Active, not recruiting | N=180 --> 360 | Trial primary completion date: Apr 2015 --> Dec 2016
- ||| Biomarker, Trial completion, Enrollment change, Immune cell: Immune Failure in Critical Therapy (INFECT) Study (clinicaltrials.gov) - Oct 26, 2016
P=N/A, N=168, Completed, Sponsor: University of Edinburgh
Recruiting --> Active, not recruiting | N=180 --> 360 | Trial primary completion date: Apr 2015 --> Dec 2016 Recruiting --> Completed | N=220 --> 168
- ||| Trial completion: ReduceIT: Reduction of Inappropriate Shocks of Implantable Cardioverter Defibrillators (ICDs) With Enhanced SVT Discriminators (clinicaltrials.gov) - Oct 25, 2016
P=N/A, N=735, Completed, Sponsor: St. Jude Medical
Recruiting --> Completed | N=220 --> 168 Active, not recruiting --> Completed
- | Trial completion: IoxRea: Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study (clinicaltrials.gov) - Oct 25, 2016
P3, N=100, Completed, Sponsor: University Hospital, Tours
Active, not recruiting --> Completed Recruiting --> Completed
- alfuzosin hydrochloride / Generic mfg.
Enrollment change, Trial withdrawal: Use of Alfuzosin in Stone Treatment With ESWL (clinicaltrials.gov) - Oct 21, 2016
P3, N=0, Withdrawn, Sponsor: Singapore General Hospital
Recruiting --> Completed N=200 --> 0 | Recruiting --> Withdrawn
- Enrollment closed, Trial primary completion date: Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury (clinicaltrials.gov) - Oct 13, 2016
P=N/A, N=20, Active, not recruiting, Sponsor: Swiss Paraplegic Centre Nottwil
N=200 --> 0 | Recruiting --> Withdrawn Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Oct 2016
- Trial completion: MC Monitor: Tolerance and Safety of a Duodenal Probe Monitoring the Microcirculation (clinicaltrials.gov) - Oct 13, 2016
P=N/A, N=10, Completed, Sponsor: Advanced Perfusion Diagnostics
Recruiting --> Active, not recruiting | Trial primary completion date: May 2016 --> Oct 2016 Recruiting --> Completed
- Trial primary completion date: CULPRIT-SHOCK: Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (clinicaltrials.gov) - Oct 11, 2016
P4, N=706, Recruiting, Sponsor: University of Luebeck
Recruiting --> Completed Trial primary completion date: Dec 2016 --> Sep 2017
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock (clinicaltrials.gov) - Sep 16, 2016
P4, N=80, Recruiting, Sponsor: Srinakharinwirot University
Trial primary completion date: Dec 2016 --> Sep 2017 Trial primary completion date: Jun 2016 --> Dec 2016
- Trial primary completion date: Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study (clinicaltrials.gov) - Sep 14, 2016
P3, N=1400, Active, not recruiting, Sponsor: Gynuity Health Projects
Trial primary completion date: Jun 2016 --> Dec 2016 Trial primary completion date: Dec 2016 --> Nov 2017
- Enrollment change, Trial termination, Trial primary completion date: FLOVAC: FLOTRAC/VIGILEO in Acute Circulatory Failure (clinicaltrials.gov) - Sep 8, 2016
P=N/A, N=1, Terminated, Sponsor: Hôpital Européen Marseille
Trial primary completion date: Dec 2016 --> Nov 2017 N=50 --> 1 | Suspended --> Terminated | Trial primary completion date: Apr 2016 --> Sep 2016; Major change in protocol anticipated
- dobutamine / Generic mfg.
Biomarker, Trial completion, Enrollment change: NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy (clinicaltrials.gov) - Sep 6, 2016
P=N/A, N=18, Completed, Sponsor: Brighton and Sussex University Hospitals NHS Trust
N=50 --> 1 | Suspended --> Terminated | Trial primary completion date: Apr 2016 --> Sep 2016; Major change in protocol anticipated Recruiting --> Completed | N=25 --> 18
- Enrollment change, Trial termination, Trial primary completion date: Observational Study of Blood Pressure Measurements and Continuous Dialysis (clinicaltrials.gov) - Aug 31, 2016
P=N/A, N=7, Terminated, Sponsor: University of Chicago
Recruiting --> Completed | N=25 --> 18 N=60 --> 7 | Recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Dec 2015
- Trial termination: NUTRIREA2: Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (clinicaltrials.gov) - Aug 26, 2016
P=N/A, N=2411, Terminated, Sponsor: Centre Hospitalier Departemental Vendee
N=60 --> 7 | Recruiting --> Terminated | Trial primary completion date: Jun 2015 --> Dec 2015 Active, not recruiting --> Terminated; stopped on Data Safety and Monitoring Board 's request
- Trial primary completion date: Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness (clinicaltrials.gov) - Aug 19, 2016
P=N/A, N=30, Recruiting, Sponsor: Hopital Louis Pradel
Active, not recruiting --> Terminated; stopped on Data Safety and Monitoring Board 's request Trial primary completion date: Jul 2016 --> Dec 2016
- | Trial completion, Trial primary completion date: Pilot Study for the SQUEEZE Trial (clinicaltrials.gov) - Aug 19, 2016
P3, N=53, Completed, Sponsor: McMaster Children's Hospital
Trial primary completion date: Jul 2016 --> Dec 2016 Recruiting --> Completed | Trial primary completion date: Jul 2015 --> Jun 2016
- Trial completion, Enrollment change: PVRS: Predicting Volume Response Study (clinicaltrials.gov) - Aug 17, 2016
P=N/A, N=7, Completed, Sponsor: University of Pennsylvania
Recruiting --> Completed | Trial primary completion date: Jul 2015 --> Jun 2016 Recruiting --> Completed | N=50 --> 7
- Trial primary completion date: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Aug 9, 2016
P3, N=360, Recruiting, Sponsor: University of Sao Paulo
Recruiting --> Completed | N=50 --> 7 Trial primary completion date: Apr 2014 --> Oct 2016
- ||||||| Trial completion: Supplemental Parenteral Nutrition in Critically Ill Adults: A Pilot Randomised Controlled Trial (clinicaltrials.gov) - Aug 3, 2016
P2/3, N=100, Completed, Sponsor: Australian and New Zealand Intensive Care Research Centre
Trial primary completion date: Apr 2014 --> Oct 2016 Recruiting --> Completed
- Biomarker, Trial completion: NeoAdapt 2: An Observational Study Investigating Novel Biomarkers in the Evaluation and Treatment of Neonatal Circulatory Insufficiency (clinicaltrials.gov) - Jul 20, 2016
P=N/A, N=25, Completed, Sponsor: Brighton and Sussex University Hospitals NHS Trust
Recruiting --> Completed Recruiting --> Completed
- Trial primary completion date: Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury (clinicaltrials.gov) - Jul 19, 2016
P1, N=20, Recruiting, Sponsor: Denver Health and Hospital Authority
Recruiting --> Completed Trial primary completion date: May 2016 --> May 2021
- ganetespib (ADX-1612) / Aldeyra, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Enrollment closed, Enrollment change, Combination therapy, Metastases: Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (clinicaltrials.gov) - Jul 12, 2016
P1, N=9, Active, not recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Trial primary completion date: May 2016 --> May 2021 Recruiting --> Active, not recruiting | N=18 --> 9
- | Enrollment closed, Trial primary completion date: Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study (clinicaltrials.gov) - Jul 12, 2016
P3, N=1400, Active, not recruiting, Sponsor: Gynuity Health Projects
Recruiting --> Active, not recruiting | N=18 --> 9 Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2016 --> Dec 2016
- Trial completion: ARDS Prediction Score in Critically Ill Patients in China (clinicaltrials.gov) - Jun 28, 2016
P=N/A, N=698, Completed, Sponsor: Jianfeng Xie
Recruiting --> Active, not recruiting | Trial primary completion date: Apr 2016 --> Dec 2016 Recruiting --> Completed
- ||||| Enrollment closed: EUPHRATES: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock (clinicaltrials.gov) - Jun 23, 2016
P3, N=450, Active, not recruiting, Sponsor: Spectral Diagnostics (US) Inc.
Recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion, Enrollment change: PPV to Guide Fluid Management in the PICU (clinicaltrials.gov) - Jun 23, 2016
P=N/A, N=100, Completed, Sponsor: University of North Carolina, Chapel Hill
Recruiting --> Active, not recruiting Enrolling by invitation --> Completed | N=150 --> 100
- Trial completion, Trial primary completion date: TAMOF: Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children (clinicaltrials.gov) - Jun 16, 2016
P=N/A, N=86, Completed, Sponsor: Children's Healthcare of Atlanta
Enrolling by invitation --> Completed | N=150 --> 100 Recruiting --> Completed | Trial primary completion date: Dec 2012 --> Feb 2012
- Trial primary completion date: The Effect of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome (clinicaltrials.gov) - Jun 15, 2016
P=N/A, N=50, Recruiting, Sponsor: Tri-Service General Hospital
Recruiting --> Completed | Trial primary completion date: Dec 2012 --> Feb 2012 Trial primary completion date: May 2016 --> May 2017
- ||| Trial completion, Trial primary completion date: 4P Study: Predictive Quality With Painfree Therapies (clinicaltrials.gov) - Jun 10, 2016
P=N/A, N=200, Completed, Sponsor: Medtronic Bakken Research Center
Trial primary completion date: May 2016 --> May 2017 Active, not recruiting --> Completed | Trial primary completion date: Jan 2016 --> May 2016
- ganetespib (ADX-1612) / Aldeyra, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Trial primary completion date, Combination therapy, Metastases: Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (clinicaltrials.gov) - Jun 10, 2016
P1, N=18, Recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Active, not recruiting --> Completed | Trial primary completion date: Jan 2016 --> May 2016 Trial primary completion date: May 2016 --> Jun 2017
- Trial completion, Enrollment change, Trial primary completion date: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - May 24, 2016
P1, N=59, Completed, Sponsor: Dr. Hasan Alam
Trial primary completion date: May 2016 --> Jun 2017 Recruiting --> Completed | N=88 --> 59 | Trial primary completion date: Dec 2016 --> May 2016
- Trial completion, Enrollment change, Trial primary completion date: The Paediatric Refill Study (PRefill) (clinicaltrials.gov) - May 20, 2016
P=N/A, N=75, Completed, Sponsor: University of Nottingham
Recruiting --> Completed | N=88 --> 59 | Trial primary completion date: Dec 2016 --> May 2016 Recruiting --> Completed | N=135 --> 75 | Trial primary completion date: Dec 2015 --> Mar 2016
- Enrollment change, Trial termination, Trial primary completion date, Surgery: Impact of Early Goal-directed Fluid Therapy in Hypovolemic Patients Undergoing Emergency Surgery (clinicaltrials.gov) - May 14, 2016
P=N/A, N=20, Terminated, Sponsor: University Hospital, Geneva
Recruiting --> Completed | N=135 --> 75 | Trial primary completion date: Dec 2015 --> Mar 2016 N=250 --> 20 | Recruiting --> Terminated | Trial primary completion date: Dec 2013 --> Jun 2014; recrutment difficulties
- Trial completion, Trial primary completion date: SEPP1B: Correlation Between PTP1B Expression and Organ Failure During Sepsis (clinicaltrials.gov) - May 13, 2016
P=N/A, N=54, Completed, Sponsor: University Hospital, Rouen
N=250 --> 20 | Recruiting --> Terminated | Trial primary completion date: Dec 2013 --> Jun 2014; recrutment difficulties Recruiting --> Completed | Trial primary completion date: Jan 2017 --> May 2016
- Trial primary completion date: Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya (clinicaltrials.gov) - May 6, 2016
P=N/A, N=440, Recruiting, Sponsor: Duke University
Recruiting --> Completed | Trial primary completion date: Jan 2017 --> May 2016 Trial primary completion date: Mar 2016 --> Aug 2016
- Trial termination, Trial primary completion date: Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial) (clinicaltrials.gov) - May 6, 2016
P=N/A, N=230, Terminated, Sponsor: Arkansas Children's Hospital Research Institute
Trial primary completion date: Mar 2016 --> Aug 2016 Recruiting --> Terminated | Trial primary completion date: Sep 2012 --> Nov 2014
- Trial primary completion date: CVPCHI: Central Venous Pressure Change With Volume Challenge in Patients With Hemodynamic Instability (clinicaltrials.gov) - May 6, 2016
P3, N=70, Completed, Sponsor: University of Monastir
Recruiting --> Terminated | Trial primary completion date: Sep 2012 --> Nov 2014 Trial primary completion date: Nov 2013 --> Apr 2013
- Trial primary completion date: Evaluation of an Absorbable Implant for the Treatment of Nasal Valve Collapse (clinicaltrials.gov) - May 3, 2016
P=N/A, N=30, Active, not recruiting, Sponsor: Spirox, Inc.
Trial primary completion date: Nov 2013 --> Apr 2013 Trial primary completion date: Dec 2015 --> May 2017
- Enrollment closed: IABP-SHOCK II: Intraaortic Balloon Pump in Cardiogenic Shock II (clinicaltrials.gov) - Apr 28, 2016
P4, N=600, Active, not recruiting, Sponsor: University of Leipzig
Trial primary completion date: Dec 2015 --> May 2017 Completed --> Active, not recruiting
- |||| Gohibic (vilobelimab) / Staidson Biopharma, InflaRx
Trial completion: SCIENS: Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction (clinicaltrials.gov) - Apr 26, 2016
P2, N=72, Completed, Sponsor: InflaRx GmbH
Completed --> Active, not recruiting Active, not recruiting --> Completed
- || Trial primary completion date: ImaCor II: Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients (clinicaltrials.gov) - Apr 16, 2016
P=N/A, N=500, Recruiting, Sponsor: University Hospital Inselspital, Berne
Active, not recruiting --> Completed Trial primary completion date: Mar 2016 --> Jan 2017