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47 Companies |
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50 Products |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- | Trial completion, Trial primary completion date: Narrow Versus Wide Focal Zones for Shock Wave Lithotripsy of Renal Calculi (clinicaltrials.gov) - Oct 6, 2017
P=N/A, N=275, Completed, Sponsor: St. Michael's Hospital, Toronto
Recruiting --> Completed | Trial primary completion date: Jun 2016 --> Nov 2016
- | Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion, Trial primary completion date: Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock (clinicaltrials.gov) - Oct 6, 2017
P4, N=80, Completed, Sponsor: Srinakharinwirot University
Recruiting --> Completed | Trial primary completion date: Jun 2016 --> Nov 2016 Recruiting --> Completed | Trial primary completion date: Dec 2016 --> May 2017
- | dobutamine / Generic mfg.
Biomarker, Trial completion, Enrollment change: Shockomics: Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock (clinicaltrials.gov) - Oct 5, 2017
P=N/A, N=70, Completed, Sponsor: Shockomics Consortium
Recruiting --> Completed | Trial primary completion date: Dec 2016 --> May 2017 Active, not recruiting --> Completed | N=115 --> 70
- | Trial completion, Enrollment change: Preemptive Resuscitation for Eradication of Septic Shock (clinicaltrials.gov) - Oct 4, 2017
P=N/A, N=142, Completed, Sponsor: Christiana Care Health Services
Active, not recruiting --> Completed | N=115 --> 70 Terminated --> Completed | N=43 --> 142
- | Enrollment change, Trial primary completion date: PALVOS: PICU Admission Lactate and Central Venous Oxymetry Study (clinicaltrials.gov) - Oct 2, 2017
P=N/A, N=50, Terminated, Sponsor: Radboud University
Terminated --> Completed | N=43 --> 142 N=500 --> 50 | Trial primary completion date: May 2014 --> Apr 2017
- | Actimmune (interferon gamma-1 b) / Clinigen, Amgen
Trial completion, Enrollment change, IO biomarker: The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis (clinicaltrials.gov) - Sep 29, 2017
P3, N=4, Completed, Sponsor: Radboud University
N=500 --> 50 | Trial primary completion date: May 2014 --> Apr 2017 Recruiting --> Completed | N=20 --> 4
- | Biomarker, Trial completion, Enrollment change: Studies of Blood DNA in Patients With Severe Infection DYNAMICS (clinicaltrials.gov) - Sep 20, 2017
P=N/A, N=792, Completed, Sponsor: Alison Fox-Robichaud
Recruiting --> Completed | N=20 --> 4 Recruiting --> Completed | N=1000 --> 792
- | Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: ADRENAL: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (clinicaltrials.gov) - Sep 7, 2017
P4, N=3800, Active, not recruiting, Sponsor: The George Institute
Recruiting --> Completed | N=1000 --> 792 Trial primary completion date: Jul 2017 --> Oct 2017
- | Trial primary completion date: Evaluation of Intestinal Brush Border Enzyme Function in Critically Ill Patients (clinicaltrials.gov) - Aug 29, 2017
P=N/A, N=39, Completed, Sponsor: Medical University of Vienna
Trial primary completion date: Jul 2017 --> Oct 2017 Trial primary completion date: Oct 2014 --> Feb 2015
- | Trial completion: Effect of APC and Epo on the Inflammatory Response During Sepsis (clinicaltrials.gov) - Aug 25, 2017
P=N/A, N=40, Completed, Sponsor: Lawson Health Research Institute
Trial primary completion date: Oct 2014 --> Feb 2015 Recruiting --> Completed
- | Trial completion: ADSeS: Examination of ADMA Serum Level and DDAH II (clinicaltrials.gov) - Aug 3, 2017
P=N/A, N=120, Completed, Sponsor: Universitätsklinikum Hamburg-Eppendorf
Recruiting --> Completed Active, not recruiting --> Completed
- | clonidine / Generic mfg.
Trial primary completion date: CATACHOC: Upregulation of Alpha-1 Receptors Upon Septic Shock? (clinicaltrials.gov) - Jul 28, 2017
P2/3, N=40, Terminated, Sponsor: Direction Centrale du Service de Santé des Armées
Active, not recruiting --> Completed Trial primary completion date: Aug 2014 --> Aug 2013
- | Phase classification: High MAP in Septic Shock With Hypertension (clinicaltrials.gov) - Jul 6, 2017
P=N/A, N=19, Completed, Sponsor: Southeast University, China
Trial primary completion date: Aug 2014 --> Aug 2013 Phase classification: P4 --> P=N/A
- ganetespib (ADX-1612) / Aldeyra, Herceptin (trastuzumab) / Roche, Perjeta (pertuzumab) / Roche
Trial primary completion date, Combination therapy, Metastases: Ganetespib, Paclitaxel, Trastuzumab and Pertuzumab for Metastatic Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (clinicaltrials.gov) - Jul 6, 2017
P1, N=9, Active, not recruiting, Sponsor: Memorial Sloan Kettering Cancer Center
Phase classification: P4 --> P=N/A Trial primary completion date: Jun 2017 --> Jun 2018
- Enrollment change, Trial termination: ASSET - a Double-Blind, Randomized Placebo-Controlled Clinical Investigation With Alteco (clinicaltrials.gov) - Jun 28, 2017
P=N/A, N=15, Terminated, Sponsor: Alteco Medical AB
Trial primary completion date: Jun 2017 --> Jun 2018 N=32 --> 15 | Recruiting --> Terminated; Problem to find eligible patients to include
- | ceftriaxone / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: PHANTASi: Prehospital Antibiotics Against Sepsis Trial (clinicaltrials.gov) - Jun 15, 2017
P=N/A, N=2672, Completed, Sponsor: VU University Medical Center
N=32 --> 15 | Recruiting --> Terminated; Problem to find eligible patients to include Recruiting --> Completed | N=2200 --> 2672 | Trial primary completion date: Jun 2016 --> Jun 2017
- | simvastatin / Generic mfg.
Enrollment change: Statin Therapy in the Treatment of Sepsis (clinicaltrials.gov) - Jun 14, 2017
P2/3, N=18, Completed, Sponsor: Beth Israel Deaconess Medical Center
Recruiting --> Completed | N=2200 --> 2672 | Trial primary completion date: Jun 2016 --> Jun 2017 N=13 --> 18
- | Leukine (sargramostim) / Partner Therap
Trial primary completion date, Metastases: Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma (clinicaltrials.gov) - May 25, 2017
P=N/A, N=23, Active, not recruiting, Sponsor: Mayo Clinic
N=13 --> 18 Trial primary completion date: Sep 2015 --> May 2017
- | dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine on Microcirculation in Septic Shock (clinicaltrials.gov) - May 17, 2017
P4, N=30, Completed, Sponsor: Southeast University, China
Trial primary completion date: Sep 2015 --> May 2017 Recruiting --> Completed
- | Trial completion, Trial primary completion date: Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness (clinicaltrials.gov) - May 5, 2017
P=N/A, N=34, Completed, Sponsor: Hopital Louis Pradel
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2016 --> May 2017
- | dexmedetomidine / Generic mfg.
Surgery: Study of Dexmedetomidine in Spine Surgery (clinicaltrials.gov) - May 5, 2017
P4, N=142, Completed, Sponsor: University of Virginia
Recruiting --> Completed | Trial primary completion date: Dec 2016 --> May 2017 Terminated --> Completed | Trial primary completion date: Dec 2016 --> May 2015
- | Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Enrollment closed, Trial primary completion date: ADRENAL: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (clinicaltrials.gov) - May 3, 2017
P4, N=3800, Active, not recruiting, Sponsor: The George Institute
Terminated --> Completed | Trial primary completion date: Dec 2016 --> May 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Jul 2017
- | Trial completion: IABP-SHOCK II: Intraaortic Balloon Pump in Cardiogenic Shock II (clinicaltrials.gov) - May 2, 2017
P4, N=600, Completed, Sponsor: University of Leipzig
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2016 --> Jul 2017 Active, not recruiting --> Completed
- | Trial completion: SHOCK-COOL: Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction (clinicaltrials.gov) - May 2, 2017
P=N/A, N=40, Completed, Sponsor: University of Leipzig
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||| Trial completion, Enrollment change, Trial initiation date, Trial primary completion date: Near Infrared Spectroscopy (St02) (clinicaltrials.gov) - Apr 26, 2017
P=N/A, N=186, Completed, Sponsor: Beth Israel Deaconess Medical Center
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=300 --> 186 | Initiation date: Sep 2008 --> Jan 2009 | Trial primary completion date: Sep 2016 --> Jan 2010
- | Trial completion, Enrollment change, Trial initiation date, Trial primary completion date: Endothelium in Severe Sepsis (clinicaltrials.gov) - Apr 26, 2017
P=N/A, N=910, Completed, Sponsor: Beth Israel Deaconess Medical Center
Active, not recruiting --> Completed | N=300 --> 186 | Initiation date: Sep 2008 --> Jan 2009 | Trial primary completion date: Sep 2016 --> Jan 2010 Recruiting --> Completed | N=600 --> 910 | Initiation date: Jun 2008 --> Mar 2008 | Trial primary completion date: Jan 2017 --> May 2013
- | Trial completion: Balanced Salt Solution VS. Normal Saline Solution in Septic Shock (clinicaltrials.gov) - Apr 26, 2017
P3, N=60, Completed, Sponsor: Ramathibodi Hospital
Recruiting --> Completed | N=600 --> 910 | Initiation date: Jun 2008 --> Mar 2008 | Trial primary completion date: Jan 2017 --> May 2013 Recruiting --> Completed
- | Ventavis (iloprost) / Bayer, J&J, University of Copenhagen, Integrilin (eptifibatide) / Takeda
Trial completion, Trial primary completion date: CO-ILEPSS: Co-administration of Iloprost and Eptifibatide in Septic Shock Patients (clinicaltrials.gov) - Apr 24, 2017
P2, N=18, Completed, Sponsor: Sisse R. Ostrowski, MD PhD DMSc
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Aug 2016
- | Trial completion, Enrollment change, Trial primary completion date: Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study (clinicaltrials.gov) - Apr 24, 2017
P3, N=635, Completed, Sponsor: Gynuity Health Projects
Recruiting --> Completed | Trial primary completion date: Aug 2015 --> Aug 2016 Active, not recruiting --> Completed | N=1400 --> 635 | Trial primary completion date: Nov 2017 --> May 2016
- | epinephrine / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: OptimaCCt: Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock (clinicaltrials.gov) - Apr 20, 2017
P4, N=58, Completed, Sponsor: Central Hospital, Nancy, France
Active, not recruiting --> Completed | N=1400 --> 635 | Trial primary completion date: Nov 2017 --> May 2016 Recruiting --> Completed | N=80 --> 58 | Trial primary completion date: Sep 2016 --> Feb 2016
- || Trial primary completion date: ImaCor II: Effects of Hemodynamic Monitoring Using the ImaCor Single Use Transesophageal Echocardiography Probe in Critically Ill Patients (clinicaltrials.gov) - Apr 13, 2017
P=N/A, N=500, Recruiting, Sponsor: University Hospital Inselspital, Berne
Recruiting --> Completed | N=80 --> 58 | Trial primary completion date: Sep 2016 --> Feb 2016 Trial primary completion date: Jan 2017 --> Sep 2017
- | Trial termination, Trial primary completion date: Control of Major Bleeding After Trauma Study (clinicaltrials.gov) - Apr 11, 2017
P2, N=144, Terminated, Sponsor: Denver Health and Hospital Authority
Trial primary completion date: Jan 2017 --> Sep 2017 Recruiting --> Terminated | Trial primary completion date: Apr 2018 --> Apr 2017; Futility
- | Phase classification: Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock (clinicaltrials.gov) - Apr 7, 2017
P=N/A, N=60, Completed, Sponsor: Baxter Healthcare Corporation
Recruiting --> Terminated | Trial primary completion date: Apr 2018 --> Apr 2017; Futility Phase classification: P3 --> P=N/A
- ceftaroline/avibactam (ceftaroline fosamil/ NXL104) / Pfizer
Enrollment change: Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance (clinicaltrials.gov) - Apr 7, 2017
P1, N=12, Completed, Sponsor: Forest Laboratories
Phase classification: P3 --> P=N/A N=24 --> 12
- | Trial primary completion date: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Mar 22, 2017
P=N/A, N=15000, Recruiting, Sponsor: Mayo Clinic
N=24 --> 12 Trial primary completion date: Dec 2016 --> Dec 2017
- ||| Trial completion, Enrollment change: THORN: Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators. (clinicaltrials.gov) - Mar 17, 2017
P=N/A, N=512, Completed, Sponsor: Biotronik SE & Co. KG
Trial primary completion date: Dec 2016 --> Dec 2017 Active, not recruiting --> Completed | N=1750 --> 512
- | Trial primary completion date: Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study (clinicaltrials.gov) - Mar 9, 2017
P=N/A, N=20, Recruiting, Sponsor: Domonkos Trásy
Active, not recruiting --> Completed | N=1750 --> 512 Trial primary completion date: Dec 2016 --> Dec 2017
- || Trial primary completion date: VENUS: Septic Gene Expression Using SeptiCyte (clinicaltrials.gov) - Mar 3, 2017
P=N/A, N=370, Active, not recruiting, Sponsor: Immunexpress
Trial primary completion date: Dec 2016 --> Dec 2017 Trial primary completion date: Dec 2016 --> Apr 2017
- | tamsulosin / Generic mfg., silodosin / Generic mfg.
Phase classification, Enrollment change: Differential Effect of Silodosin Versus Tamsulosin on Stone Clearance After Extra-corporeal Shock Wave Lithotripsy (clinicaltrials.gov) - Feb 17, 2017
P3, N=0, Withdrawn, Sponsor: Albert Einstein Healthcare Network
Trial primary completion date: Dec 2016 --> Apr 2017 Phase classification: P=N/A --> P3 | N=90 --> 0
- Phase classification, Surgery: HEROICS: High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock (clinicaltrials.gov) - Feb 12, 2017
P=N/A, N=226, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
Phase classification: P=N/A --> P3 | N=90 --> 0 Phase classification: P3 --> P=N/A
- Trial primary completion date: Control of Major Bleeding After Trauma Study (clinicaltrials.gov) - Feb 12, 2017
P2, N=150, Recruiting, Sponsor: Denver Health and Hospital Authority
Phase classification: P3 --> P=N/A Trial primary completion date: Apr 2017 --> Apr 2018
- Enrollment change, Trial termination: Intraoperative Dialysis in Liver Transplantation (clinicaltrials.gov) - Feb 7, 2017
P2, N=32, Terminated, Sponsor: University of Alberta
Trial primary completion date: Apr 2017 --> Apr 2018 N=50 --> 32 | Recruiting --> Terminated; Insufficient funding.
- Enrollment change, Trial termination: IDEAL-ICU: I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) (clinicaltrials.gov) - Feb 2, 2017
P3, N=500, Terminated, Sponsor: Centre Hospitalier Universitaire Dijon
N=50 --> 32 | Recruiting --> Terminated; Insufficient funding. N=864 --> 500 | Recruiting --> Terminated
- Trial completion: The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=45, Completed, Sponsor: Mercy Research
N=864 --> 500 | Recruiting --> Terminated Not yet recruiting --> Completed
- Trial primary completion date: Cerebral Autoregulation in Non Neurological Critical Patients. (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=100, Recruiting, Sponsor: Althaia Xarxa Assistencial Universitària de Manresa
Not yet recruiting --> Completed Trial primary completion date: Dec 2016 --> Dec 2017
- Trial completion: Extracorporeal Shock Wave Therapy (ESWT) for the Treatment of Spasticity in Persons With Spinal Cord Injury (clinicaltrials.gov) - Jan 26, 2017
P=N/A, N=20, Completed, Sponsor: Swiss Paraplegic Centre Nottwil
Trial primary completion date: Dec 2016 --> Dec 2017 Active, not recruiting --> Completed
- Enrollment change, Trial withdrawal: Presep and Vascath Interaction Study (clinicaltrials.gov) - Jan 24, 2017
P=N/A, N=0, Withdrawn, Sponsor: Wake Forest University Health Sciences
Active, not recruiting --> Completed N=100 --> 0 | Terminated --> Withdrawn
- Trial completion: EVAKIN: Clinical Evaluation of Swallowing Disorders as a Predictor of Extubation Failure (clinicaltrials.gov) - Jan 4, 2017
P=N/A, N=160, Completed, Sponsor: Assistance Publique - H
N=100 --> 0 | Terminated --> Withdrawn Recruiting --> Completed
- Trial completion: ESWTvsED: Low-energy Linear Extracorporal Shock Wave Therapy for Erectile Dysfunction. (clinicaltrials.gov) - Dec 28, 2016
P=N/A, N=126, Completed, Sponsor: Grzegorz Fojecki
Recruiting --> Completed Active, not recruiting --> Completed
- midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
Clinical: The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis (clinicaltrials.gov) - Dec 21, 2016
P4, N=60, Recruiting, Sponsor: National Taiwan University Hospital
Active, not recruiting --> Completed Trial primary completion date: Jun 2017 --> Jun 2018