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47 Companies |
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50 Products |
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66 Mechanisms of Action |
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978 News |
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- ||| Trial completion: Enhanced Surveillance of RV Lead Integrity Alert (RVLIA) (clinicaltrials.gov) - Jun 23, 2013
P=N/A, N=1779, Completed, Sponsor: Medtronic Cardiac Rhythm Disease Management
Active, not recruiting --> Completed
- Trial completion: IABP-SHOCK II: Intraaortic Balloon Pump in Cardiogenic Shock II (clinicaltrials.gov) - Jun 16, 2013
P4, N=600, Completed, Sponsor: University of Leipzig
Active, not recruiting --> Completed Recruiting --> Completed
- || New P3 trial: Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) (clinicaltrials.gov) - Jun 6, 2013
P3, N=1500, Enrolling by invitation, Sponsor: Lawson Health Research Institute
- Inomax (nitric oxide) / Mallinckrodt
Enrollment change: Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis (clinicaltrials.gov) - Jun 2, 2013
P3, N=49, Completed, Sponsor: National Institute of General Medical Sciences (NIGMS)
Recruiting --> Completed N=138 --> 49
- Enrollment open: OVATION: Optimal VAsopressor titraTION Pilot Randomized Controlled Trial (clinicaltrials.gov) - Jun 2, 2013
P=N/A, N=80, Recruiting, Sponsor: Francois Lamontagne
N=138 --> 49 Not yet recruiting --> Recruiting
- Inomax (nitric oxide) / Mallinckrodt
Trial completion: Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis (clinicaltrials.gov) - Jun 2, 2013
P3, N=49, Completed, Sponsor: National Institute of General Medical Sciences (NIGMS)
Not yet recruiting --> Recruiting Recruiting --> Completed
- New P1 trial: CIPNM: The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis (clinicaltrials.gov) - Jun 2, 2013
P1, N=38, Terminated, Sponsor: Medical University of Vienna
- Enrollment closed: Effects of Free Fatty Acids and 3-hydroxybutyrate on Protein, Glucose, Lipid Metabolism and Intracellular Signals. (clinicaltrials.gov) - May 23, 2013
P=N/A, N=10, Active, not recruiting, Sponsor: University of Aarhus
Recruiting --> Completed Recruiting --> Active, not recruiting
- Byetta (exenatide) / AstraZeneca
Trial withdrawal: Pharmacology of Exenatide in Pediatric Sepsis (clinicaltrials.gov) - May 23, 2013
P1/2, N=0, Withdrawn, Sponsor: Seattle Children's Hospital
Recruiting --> Active, not recruiting Not yet recruiting --> Withdrawn
- Byetta (exenatide) / AstraZeneca
Enrollment change: Pharmacology of Exenatide in Pediatric Sepsis (clinicaltrials.gov) - May 23, 2013
P1/2, N=0, Withdrawn, Sponsor: Seattle Children's Hospital
Not yet recruiting --> Withdrawn N=100 --> 0
- clonidine / Generic mfg.
New P2/3 trial: CATACHOC: Upregulation of Alpha-1 Receptors Upon Septic Shock? (clinicaltrials.gov) - May 15, 2013
P2/3, N=40, Recruiting, Sponsor: Direction Centrale du Service de Santé des Armées
- luminespib (AUY922) / Ligand, Herceptin (trastuzumab) / Roche
Enrollment change, Metastases: AUY922: 89Zr-trastuzumab PET for Imaging the Effect of HSP90 Inhibition (clinicaltrials.gov) - May 12, 2013
P1, N=7, Completed, Sponsor: University Medical Centre Groningen
N=100 --> 0 N=11 --> 7
- | dexmedetomidine / Generic mfg.
Surgery: Study of Dexmedetomidine in Spine Surgery (clinicaltrials.gov) - May 7, 2013
P4, N=250, Recruiting, Sponsor: University of Virginia
- |||||||||| New P2/3 trial: Supplemental Parenteral Nutrition in Critically Ill Adults: A Pilot Randomised Controlled Trial (clinicaltrials.gov) - May 5, 2013
P2/3, N=100, Not yet recruiting, Sponsor: Australian and New Zealand Intensive Care Research Centre
- | Trial termination: GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock (clinicaltrials.gov) - Apr 28, 2013
P3, N=214, Terminated, Sponsor: Green Cross Corporation
N=11 --> 7 Suspended --> Terminated
- Trial initiation date: HypoResus: Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma (clinicaltrials.gov) - Apr 22, 2013
P2, N=192, Completed, Sponsor: University of Washington
Suspended --> Terminated Initiation date: Oct 2011 --> Mar 2012
- | New P2 trial: Control of Major Bleeding After Trauma Study (clinicaltrials.gov) - Apr 22, 2013
P2, N=150, Not yet recruiting, Sponsor: Denver Health and Hospital Authority
- Trial completion: HypoResus: Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma (clinicaltrials.gov) - Apr 22, 2013
P2, N=192, Completed, Sponsor: University of Washington
Initiation date: Oct 2011 --> Mar 2012 Recruiting --> Completed
- Enrollment change: Hemoglobin Saturation in Superior Vena Cava and Right Atrium (clinicaltrials.gov) - Apr 18, 2013
P=N/A, N=61, Completed, Sponsor: Catholic University of the Sacred Heart
Recruiting --> Completed N=40 --> 61
- Trial completion: Hemoglobin Saturation in Superior Vena Cava and Right Atrium (clinicaltrials.gov) - Apr 18, 2013
P=N/A, N=61, Completed, Sponsor: Catholic University of the Sacred Heart
N=40 --> 61 Recruiting --> Completed
- azithromycin / Generic mfg.
Trial suspension, IO biomarker, Immunomodulating: Efficacy of Macrolide Immunomodulation in Severe Sepsis. (clinicaltrials.gov) - Apr 16, 2013
P2, N=100, Suspended, Sponsor: Department of Veterans Affairs
Recruiting --> Completed Recruiting --> Suspended
- Enrollment closed: Effect of Shock Waves on Tooth Movement and Miniscrew Stability (clinicaltrials.gov) - Apr 15, 2013
P2/3, N=30, Active, not recruiting, Sponsor: Medical University of Vienna
Recruiting --> Suspended Recruiting --> Active, not recruiting
- | Enrollment closed: Effect of Shock Waves on Dental Parameters (clinicaltrials.gov) - Apr 15, 2013
P2/3, N=72, Active, not recruiting, Sponsor: Medical University of Vienna
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- Trial completion: Lung Collapse With Bronchial Blocker (clinicaltrials.gov) - Apr 15, 2013
P=N/A, N=40, Completed, Sponsor: Laval University
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial initiation date: CSWTSPB40: Estimation of the Long Term Effectiveness of Routine Use of Cardiac Shock Wave Therapy (clinicaltrials.gov) - Apr 13, 2013
P=N/A, N=0, Withdrawn, Sponsor: City Hospital No 40, Saint Petersburg, Russia
Recruiting --> Completed Initiation date: Oct 2012 --> Sep 2013
- ||||||| Trial completion: Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock (clinicaltrials.gov) - Apr 8, 2013
P3, N=60, Completed, Sponsor: Gambro Lundia AB
Initiation date: Oct 2012 --> Sep 2013 Active, not recruiting --> Completed
- |||| Trial completion: Phase IIb Study of MP4OX in Traumatic Hemorrhagic Shock Patients (clinicaltrials.gov) - Apr 2, 2013
P2b, N=348, Completed, Sponsor: Sangart
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment open: NUTRIREA2: Impact of Early Enteral vs. Parenteral Nutrition on Mortality in Patients Requiring Mechanical Ventilation and Catecholamines (clinicaltrials.gov) - Mar 20, 2013
P=N/A, N=2854, Recruiting, Sponsor: Centre Hospitalier Departemental Vendee
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ||||||| zoledronic acid / Generic mfg.
Trial completion: EZAPCOFH: Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head (clinicaltrials.gov) - Mar 14, 2013
P3, N=104, Completed, Sponsor: Seoul National University Bundang Hospital
Not yet recruiting --> Recruiting Recruiting --> Completed
- Enrollment open: Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Mar 5, 2013
P=N/A, N=30, Recruiting, Sponsor: Policlinico Hospital
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: NASA: Role of Neutrophil Activation in Anaphylaxis to Neuro-Muscular Blocking Agents (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=200, Recruiting, Sponsor: Assistance Publique - H
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial initiation date: High Dose Vitamin C in the Critically Ill Patient (clinicaltrials.gov) - Feb 27, 2013
P2, N=60, Recruiting, Sponsor: Rutgers, The State University of New Jersey
Not yet recruiting --> Recruiting Initiation date: Mar 2012 --> Feb 2013
- IO biomarker: Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients (clinicaltrials.gov) - Feb 27, 2013
P=N/A, N=1, Recruiting, Sponsor: Chinese PLA General Hospital
- Enrollment change: EARTH-ICU: Early Physical Therapy in Patients With Sepsis (clinicaltrials.gov) - Feb 24, 2013
P=N/A, N=36, Recruiting, Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Initiation date: Mar 2012 --> Feb 2013 N=22 --> 36
- Enrollment open: EARTH-ICU: Early Physical Therapy in Patients With Sepsis (clinicaltrials.gov) - Feb 24, 2013
P=N/A, N=36, Recruiting, Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain
N=22 --> 36 Not yet recruiting --> Recruiting
- Enrollment open: Echocardiographic Prediction of Fluid Responsiveness After a Mini-fluid Challenge in Non-ventilated Patients With Shock (clinicaltrials.gov) - Feb 17, 2013
P=N/A, N=70, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||| Trial completion: Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients (clinicaltrials.gov) - Feb 14, 2013
P=N/A, N=300, Completed, Sponsor: The Cleveland Clinic
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment change: BICUK: BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
Active, not recruiting --> Completed N=20 --> 51
- Enrollment change: NICUPS: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
N=20 --> 51 N=200 --> 51
- Trial completion: BICUK: BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
N=200 --> 51 Recruiting --> Completed
- Trial completion: NICUPS: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
Recruiting --> Completed Recruiting --> Completed
- esmolol / Generic mfg.
Enrollment change: Heart Rate Control With Esmolol in Septic Shock (clinicaltrials.gov) - Jan 22, 2013
P2, N=154, Completed, Sponsor: Andrea Morelli
Recruiting --> Completed N=100 --> 154
- esmolol / Generic mfg.
Trial completion: Heart Rate Control With Esmolol in Septic Shock (clinicaltrials.gov) - Jan 22, 2013
P2, N=154, Completed, Sponsor: Andrea Morelli
N=100 --> 154 Recruiting --> Completed
- Clinical: Dose-response Study of Arginine Supplementation in Severe Sepsis (clinicaltrials.gov) - Jan 22, 2013
P0, N=8, Completed, Sponsor: Maastricht University Medical Center
- Enrollment closed: Autonomic Nervous Activity During the Systemic Inflammatory Response in Trained and Untrained Healthy Volunteers (clinicaltrials.gov) - Jan 16, 2013
P0, N=24, Active, not recruiting, Sponsor: Rigshospitalet, Denmark
Recruiting --> Completed Recruiting --> Active, not recruiting
- ||||||| eritoran (E5564) / Eisai
Trial completion: ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis (clinicaltrials.gov) - Jan 1, 2013
P3, N=2000, Completed, Sponsor: Eisai Inc.
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- Trial completion: Evaluation of the Safety and Immune Response of Five Admixtures of a Tetravalent Dengue Virus Vaccine (clinicaltrials.gov) - Dec 30, 2012
P1, N=141, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients (clinicaltrials.gov) - Dec 20, 2012
P=N/A, N=1200, Recruiting, Sponsor: Shanghai 10th People's Hospital
Active, not recruiting --> Completed N=800 --> 1200
- Trial termination: Minimally Invasive Tongue Suture For Obstructive Sleep Apnea (clinicaltrials.gov) - Dec 17, 2012
P=N/A, N=5, Terminated, Sponsor: West Side ENT
N=800 --> 1200 Recruiting --> Terminated; Results from first few subjects was not significantly improved over standard, traditional procedures.
- Enrollment open: Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients (clinicaltrials.gov) - Dec 15, 2012
P=N/A, N=1200, Recruiting, Sponsor: Shanghai 10th People's Hospital
Recruiting --> Terminated; Results from first few subjects was not significantly improved over standard, traditional procedures. Not yet recruiting --> Recruiting