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47 Companies |
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50 Products |
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66 Mechanisms of Action |
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0 Trials |
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978 News |
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- | Enrollment change, Surgery: HEROICS: High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock (clinicaltrials.gov) - Nov 12, 2013
P3, N=226, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
N=330 --> 226
- | Trial completion, Surgery: HEROICS: High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock (clinicaltrials.gov) - Nov 12, 2013
P3, N=226, Completed, Sponsor: Assistance Publique - Hôpitaux de Paris
N=330 --> 226 Recruiting --> Completed
- Trial completion, IO biomarker: Safety of and Immune Response to a Dengue Virus Vaccine (rDEN3delta30/31-7164) in Healthy Adults (clinicaltrials.gov) - Nov 12, 2013
P1, N=56, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting --> Completed Active, not recruiting --> Completed
- ||| Enrollment open: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Nov 10, 2013
P=N/A, N=5000, Recruiting, Sponsor: Mayo Clinic
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- ampreloxetine (TD-9855) / Theravance Biopharma
Trial completion: Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction. (clinicaltrials.gov) - Nov 10, 2013
P4, N=61, Completed, Sponsor: Oslo University Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- | Trial initiation date: Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) (clinicaltrials.gov) - Nov 4, 2013
P3, N=1500, Enrolling by invitation, Sponsor: Lawson Health Research Institute
Not yet recruiting --> Completed Initiation date: Jul 2013 --> Nov 2013
- piperacillin sodium/tazobactam sodium / Generic mfg., doripenem / Generic mfg.
Enrollment change: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients (clinicaltrials.gov) - Nov 4, 2013
P=N/A, N=50, Completed, Sponsor: University Hospital, Montpellier
Initiation date: Jul 2013 --> Nov 2013 N=40 --> 50
- | Enrollment open: Efficacy of Antimicrobial Prophylaxis for Shock Wave Lithotripsy (SWL) on Reducing Urinary Tract Infection (UTI) (clinicaltrials.gov) - Nov 4, 2013
P3, N=1500, Enrolling by invitation, Sponsor: Lawson Health Research Institute
N=40 --> 50 Not yet recruiting --> Enrolling by invitation
- Enrollment open: The Use of the USCOM Device in Addition to Cardiac Ultrasound in Patients Undergoing Treatment for Undifferentiated Shock (clinicaltrials.gov) - Nov 4, 2013
P=N/A, N=200, Recruiting, Sponsor: Minneapolis Medical Research Foundation
Not yet recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- piperacillin sodium/tazobactam sodium / Generic mfg., doripenem / Generic mfg.
Trial completion: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients (clinicaltrials.gov) - Nov 4, 2013
P=N/A, N=50, Completed, Sponsor: University Hospital, Montpellier
Not yet recruiting --> Recruiting Recruiting --> Completed
- clonidine / Generic mfg.
Trial initiation date: CATACHOC: Upregulation of Alpha-1 Receptors Upon Septic Shock? (clinicaltrials.gov) - Nov 3, 2013
P2/3, N=40, Recruiting, Sponsor: Direction Centrale du Service de Santé des Armées
Recruiting --> Completed Initiation date: Apr 2013 --> Aug 2013
- | Enrollment open: HEMOSEPSIS: Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock (clinicaltrials.gov) - Oct 30, 2013
P3, N=153, Recruiting, Sponsor: University Hospital, Limoges
Initiation date: Apr 2013 --> Aug 2013 Not yet recruiting --> Recruiting
- New P3 trial: Pilot Study for the SQUEEZE Trial (clinicaltrials.gov) - Oct 30, 2013
P3, N=50, Recruiting, Sponsor: McMaster Children's Hospital
- New P2 trial: Phase 2c Dose Comparison Study of MP4OX in Trauma (clinicaltrials.gov) - Oct 29, 2013
P2, N=0, Withdrawn, Sponsor: Sangart
- Trial completion: Early Haemodynamic Optimization Using Preload Dependence During Septic Shock = EHOSS-1 (clinicaltrials.gov) - Oct 29, 2013
P=N/A, N=61, Completed, Sponsor: Hospices Civils de Lyon
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- Trial completion: Extracorporeal Shock Wave Treatment for Cellulite (clinicaltrials.gov) - Oct 27, 2013
P=N/A, N=14, Completed, Sponsor: Concept-Clinic
Not yet recruiting --> Completed Not yet recruiting --> Completed
- Trial completion: PFFT2: Pediatric Fast Fluid Trial 2 (clinicaltrials.gov) - Oct 25, 2013
P=N/A, N=16, Completed, Sponsor: McMaster Children's Hospital
Not yet recruiting --> Completed Not yet recruiting --> Completed
- Trial withdrawal: Phase 2c Dose Comparison Study of MP4OX in Trauma (clinicaltrials.gov) - Oct 24, 2013
P2, N=0, Withdrawn, Sponsor: Sangart
Not yet recruiting --> Completed Not yet recruiting --> Withdrawn
- || Enrollment closed: IMproved PREdiction of Severe Sepsis in the Emergency Department (clinicaltrials.gov) - Oct 24, 2013
P=N/A, N=1000, Active, not recruiting, Sponsor: Axis Shield Diagnostics Ltd
Not yet recruiting --> Withdrawn Recruiting --> Active, not recruiting
- Enrollment open: The AVERT Sepsis Investigation (clinicaltrials.gov) - Oct 20, 2013
P=N/A, N=100, Recruiting, Sponsor: Christiana Care Health Services
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- | Trial initiation date: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Oct 15, 2013
P3, N=360, Recruiting, Sponsor: University of Sao Paulo
Not yet recruiting --> Recruiting Initiation date: Jan 2013 --> Oct 2013
- | Enrollment open: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Oct 15, 2013
P3, N=360, Recruiting, Sponsor: University of Sao Paulo
Initiation date: Jan 2013 --> Oct 2013 Not yet recruiting --> Recruiting
- Enrollment closed: Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy (clinicaltrials.gov) - Oct 14, 2013
P=N/A, N=12, Active, not recruiting, Sponsor: University of Missouri, Kansas City
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- |||| Trial completion: OPTION: Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications (clinicaltrials.gov) - Oct 13, 2013
P4, N=461, Completed, Sponsor: Sorin Group
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||| Enrollment open: ReduceIT: Reduction of Inappropriate Shocks of Implantable Cardioverter Defibrillators (ICDs) With Enhanced SVT Discriminators (clinicaltrials.gov) - Oct 10, 2013
P=N/A, N=697, Recruiting, Sponsor: St. Jude Medical
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | ceftaroline/avibactam (ceftaroline fosamil/ NXL104) / Pfizer
Trial completion: Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance (clinicaltrials.gov) - Oct 10, 2013
P1, N=24, Completed, Sponsor: Cerexa, Inc.
Not yet recruiting --> Recruiting Recruiting --> Completed
- | simvastatin / Generic mfg.
Enrollment open: Statin Therapy in the Treatment of Sepsis (clinicaltrials.gov) - Oct 7, 2013
P2/3, N=60, Recruiting, Sponsor: Beth Israel Deaconess Medical Center
Recruiting --> Completed Active, not recruiting --> Recruiting
- Clinical: Investigate the Activity of Endotoxin in Severe Sepsis (clinicaltrials.gov) - Oct 6, 2013
P=N/A, N=60, Recruiting, Sponsor: National Taiwan University Hospital
- | hydrocortisone / Generic mfg.
Trial completion: HYPRESS: Hydrocortisone for Prevention of Septic Shock (clinicaltrials.gov) - Sep 25, 2013
P3, N=380, Completed, Sponsor: Charite University, Berlin, Germany
Active, not recruiting --> Recruiting Recruiting --> Completed
- Trial completion: Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis (clinicaltrials.gov) - Sep 25, 2013
P=N/A, N=50, Completed, Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Recruiting --> Completed Recruiting --> Completed
- Biomarker, Enrollment open: LDH as a Biochemical Biomarker to Predict Organ Failure in the Emergency Department Setting (clinicaltrials.gov) - Sep 23, 2013
P=N/A, N=2500, Recruiting, Sponsor: Karolinska Institutet
Recruiting --> Completed Not yet recruiting --> Recruiting
- New P1 trial: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - Sep 22, 2013
P1, N=88, Recruiting, Sponsor: Dr. Hasan Alam
- Enrollment open: A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1) (clinicaltrials.gov) - Sep 22, 2013
P1, N=88, Recruiting, Sponsor: Dr. Hasan Alam
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Clinical: Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department (clinicaltrials.gov) - Sep 18, 2013
P=N/A, N=400, Recruiting, Sponsor: Chulalongkorn University
- Enrollment open: High Dose Vitamin C in the Critically Ill Patient (clinicaltrials.gov) - Sep 15, 2013
P2, N=60, Recruiting, Sponsor: Rutgers, The State University of New Jersey
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Enrollment open, Surgery: Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery (clinicaltrials.gov) - Sep 11, 2013
P=N/A, N=60, Recruiting, Sponsor: University of Cologne
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | New P4 trial: CULPRIT-SHOCK: Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (clinicaltrials.gov) - Aug 20, 2013
P4, N=706, Recruiting, Sponsor: University of Luebeck
- Enrollment open: German Lactat Clearance in Severe Sepsis (clinicaltrials.gov) - Aug 20, 2013
P=N/A, N=300, Recruiting, Sponsor: RWTH Aachen University
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | ampreloxetine (TD-9855) / Theravance Biopharma
New P4 trial: Levosimendan in Acute Heart Failure Following Acute Myocardial Infarction. (clinicaltrials.gov) - Aug 14, 2013
P4, N=61, Completed, Sponsor: Oslo University Hospital
- Enrollment open, Review: Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units (clinicaltrials.gov) - Aug 6, 2013
P=N/A, N=1100, Recruiting, Sponsor: National Taiwan University Hospital
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- || Enrollment change: Procalcitonin Monitoring Sepsis Study (clinicaltrials.gov) - Jul 24, 2013
P=N/A, N=800, Recruiting, Sponsor: Brahms AG
Not yet recruiting --> Recruiting N=360 --> 800
- Trial completion: Sub-threshold Pacing to Prevent Pacemaker-induced Ventricular Tachycardia (clinicaltrials.gov) - Jul 22, 2013
P=N/A, N=550, Completed, Sponsor: Johannes Gutenberg University Mainz
N=360 --> 800 Not yet recruiting --> Completed
- Enrollment open: Lung and Systemic Inflammation in the Critically Ill Patient (clinicaltrials.gov) - Jul 18, 2013
P=N/A, N=18, Recruiting, Sponsor: Rigshospitalet, Denmark
Not yet recruiting --> Completed Not yet recruiting --> Recruiting
- |||| Trial completion: A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock (clinicaltrials.gov) - Jul 18, 2013
P2b, N=300, Completed, Sponsor: AstraZeneca
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- || cyclosporin A microemulsion / Generic mfg.
New P3 trial: CLOTILDE: Cyclosporine in Acute Myocardial Infarction Complicated by Cardiogenic Shock (clinicaltrials.gov) - Jul 15, 2013
P3, N=100, Not yet recruiting, Sponsor: Hospices Civils de Lyon
- Trial withdrawal, Surgery: HICOSIRS: High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery (clinicaltrials.gov) - Jul 7, 2013
P=N/A, N=0, Withdrawn, Sponsor: Gambro Dialysatoren GmbH
Active, not recruiting --> Completed Recruiting --> Withdrawn
- Enrollment change, Surgery: HICOSIRS: High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery (clinicaltrials.gov) - Jul 7, 2013
P=N/A, N=0, Withdrawn, Sponsor: Gambro Dialysatoren GmbH
Recruiting --> Withdrawn N=70 --> 0
- Trial completion: Trop-Shock DFT-testing Versus None (clinicaltrials.gov) - Jul 2, 2013
P4, N=195, Completed, Sponsor: Deutsches Herzzentrum Muenchen
N=70 --> 0 Active, not recruiting --> Completed
- | Trial completion: SISPCT: Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (clinicaltrials.gov) - Jun 27, 2013
P3, N=1180, Completed, Sponsor: Kompetenznetz Sepsis
Active, not recruiting --> Completed Active, not recruiting --> Completed
- || Enrollment change: Enhanced Surveillance of RV Lead Integrity Alert (RVLIA) (clinicaltrials.gov) - Jun 23, 2013
P=N/A, N=1779, Completed, Sponsor: Medtronic Cardiac Rhythm Disease Management
Active, not recruiting --> Completed N=3873 --> 1779