Sezary Syndrome MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	3	6	9	12	15	18	21	24	27	30



HIF-1 inhib




HMG-CoA reductase inhib




Hematopoietic stem cell mobilizer




Histamine release inhib




IL-10 stim




IL-12 inhib




Ionizing radiation emitter




Kappa receptor agon




Nerve growth factor inhib




Nicotinamide phosphoribosyltransferase inhib




Notch inhib




PARP2 inhib




PI3K inhib




PNPase inhib




Plasma retinol binding protein inhib




Protein 30S ribosomal subunit inhib




RAF kinase inhib




Retinoid X receptor mod




STAT3 inhib




Serotonin 3 receptor antag




TLR9 agon




Telomerase inhib




α-secretase mod



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