Serotonin Syndrome MOAs - LARVOL Sigma

Serotonin Syndrome

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31 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	2										4										6										8										10										12										14										16										18										20



PDGFR inhib




VEGFR inhib




mTOR inhib




Tubulin inhib




EGFR mutation inhib




IFNα stim




PDGFR inhib




c-KIT inhib




IFNα stim




mTOR inhib




AKT inhib




BRAF inhib




DNA cross linking agent




HIF-1 inhib




IGF-1R inhib




Tubulin inhib




Angiogenesis inhib




Bcl2 inhib




Bcl2 inhib




FGFR3 inhib




HER2 inhib




HIF-1 inhib




Histamine release inhib




ITK inhib




MAOB inhib




Protease inhib




Proteasome inhib




RAF kinase inhib




SSTR agon




STAT3 inhib




Somatostatin inhib




TNF inhib