|
55 Companies |
|
51 Products |
|
51 Products |
|
62 Mechanisms of Action |
|
0 Trials |
|
1119 News |
|
| «12345678910111213...1920» |
- esmolol / Generic mfg.
Trial completion, Trial primary completion date: Echocardiographic and Arterial Pressure Waveform Changes After Reducing Heart Rate With Esmolol in Septic Shock Patients (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=45, Completed, Sponsor: University of Roma La Sapienza
Recruiting --> Completed | Trial primary completion date: Nov 2014 --> Jun 2014
- Trial completion: Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae (clinicaltrials.gov) - Aug 11, 2015
P=N/A, N=1064, Completed, Sponsor: Fundación Pública Andaluza Progreso y Salud
Recruiting --> Completed | Trial primary completion date: Nov 2014 --> Jun 2014 Recruiting --> Completed
- | Trial completion: rTSST-1 Variant Vaccine Phase 1 (clinicaltrials.gov) - Jul 25, 2015
P1, N=46, Completed, Sponsor: Biomedizinische Forschungs gmbH
Recruiting --> Completed Recruiting --> Completed
- |||| Enrollment open, Trial initiation date: Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients (clinicaltrials.gov) - Jul 22, 2015
P2, N=110, Recruiting, Sponsor: Isomark, LLC
Recruiting --> Completed Not yet recruiting --> Recruiting | Initiation date: Jan 2015 --> Apr 2015
- Biomarker, Trial withdrawal: Multi-marker INDex for the Risk Assessment of Sepsis in the Emergency departmenT (MINDSET) (clinicaltrials.gov) - Jul 21, 2015
P=N/A, N=0, Withdrawn, Sponsor: Biosite
Not yet recruiting --> Recruiting | Initiation date: Jan 2015 --> Apr 2015 Terminated --> Withdrawn
- Enrollment closed: Preemptive Resuscitation for Eradication of Septic Shock (clinicaltrials.gov) - Jul 17, 2015
P=N/A, N=140, Active, not recruiting, Sponsor: Christiana Care Health Services
Terminated --> Withdrawn Recruiting --> Active, not recruiting
- Trial completion, Trial primary completion date: EMOS: Procurement of Human Specimens for the Evaluation of Early Markers of Sepsis (clinicaltrials.gov) - Jul 10, 2015
P=N/A, N=872, Completed, Sponsor: Abbott Diagnostics Division
Recruiting --> Active, not recruiting Active, not recruiting --> Completed | Trial primary completion date: Dec 2014 --> Aug 2014
- Trial withdrawal: SLIC: A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemia (clinicaltrials.gov) - Jun 30, 2015
P1/2, N=0, Withdrawn, Sponsor: AM-Pharma
Active, not recruiting --> Completed | Trial primary completion date: Dec 2014 --> Aug 2014 Terminated --> Withdrawn
- Trial primary completion date: Early Goal Directed Therapy in Sepsis by Emergency Medical Services (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=200, Recruiting, Sponsor: Massachusetts General Hospital
Terminated --> Withdrawn Trial primary completion date: May 2015 --> May 2016
- dobutamine / Generic mfg.
Trial completion, Trial primary completion date: Effects of Dobutamine on Microcirculation, Regional and Peripheral Perfusion in Septic Shock Patients (clinicaltrials.gov) - Jun 26, 2015
P=N/A, N=20, Completed, Sponsor: Pontificia Universidad Catolica de Chile
Trial primary completion date: May 2015 --> May 2016 Recruiting --> Completed | Trial primary completion date: Aug 2012 --> Jan 2013
- || Cubicin (daptomycin) / Merck (MSD)
Trial primary completion date: Safety & Efficacy of Daptomycin Versus Standard of Care (SOC) in 1 - 17 Year Olds With Staphylococcus Aureus Bacteremia (MK-3009-005) (clinicaltrials.gov) - Jun 23, 2015
P4, N=75, Recruiting, Sponsor: Cubist Pharmaceuticals
Recruiting --> Completed | Trial primary completion date: Aug 2012 --> Jan 2013 Trial primary completion date: Dec 2015 --> Apr 2016
- Trial primary completion date: Impact of Dopamine Infusion on Insulin Secretion in Healthy Subjects (clinicaltrials.gov) - Jun 23, 2015
P1, N=15, Recruiting, Sponsor: Albert Einstein College of Medicine of Yeshiva University
Trial primary completion date: Dec 2015 --> Apr 2016 Trial primary completion date: Feb 2015 --> Jul 2016
- Enrollment change, Trial withdrawal, Trial primary completion date: Different Modes of Temperature Measurement in the Emergency Department (clinicaltrials.gov) - Jun 18, 2015
P3, N=0, Withdrawn, Sponsor: HaEmek Medical Center, Israel
Trial primary completion date: Feb 2015 --> Jul 2016 N=500 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jan 2016 --> Jan 2015
- ||| Enrollment open: PPV to Guide Fluid Management in the PICU (clinicaltrials.gov) - Jun 16, 2015
P=N/A, N=150, Enrolling by invitation, Sponsor: University of North Carolina, Chapel Hill
N=500 --> 0 | Not yet recruiting --> Withdrawn | Trial primary completion date: Jan 2016 --> Jan 2015 Not yet recruiting --> Enrolling by invitation
- Trial completion: Phase I STEBVax in Healthy Adults (clinicaltrials.gov) - Jun 15, 2015
P1, N=29, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting --> Enrolling by invitation Active, not recruiting --> Completed
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial primary completion date: Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock (clinicaltrials.gov) - Jun 11, 2015
P4, N=80, Recruiting, Sponsor: Srinakharinwirot University
Active, not recruiting --> Completed Trial primary completion date: Dec 2015 --> Jun 2016
- || Trial primary completion date: Detecting Infections Rapidly and Easily for Bacteremia Trial (DIREBT) (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=700, Recruiting, Sponsor: T2 Biosystems
Trial primary completion date: Dec 2015 --> Jun 2016 Trial primary completion date: Aug 2014 --> Aug 2015
- || leflunomide / Generic mfg.
Trial primary completion date: An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria (clinicaltrials.gov) - Jun 11, 2015
P2, N=60, Recruiting, Sponsor: Changzheng-Cinkate
Trial primary completion date: Aug 2014 --> Aug 2015 Trial primary completion date: Jul 2014 --> Dec 2015
- | piperacillin / Generic mfg.
Trial completion: PK Analysis of Piperacillin in Septic Shock Patients (clinicaltrials.gov) - Jun 11, 2015
P=N/A, N=15, Completed, Sponsor: University of Aarhus
Trial primary completion date: Jul 2014 --> Dec 2015 Recruiting --> Completed
- Phase classification, Trial primary completion date: PreColos: Feeding Bovine Colostrum to Preterm Infants (clinicaltrials.gov) - Jun 4, 2015
P1/2, N=50, Recruiting, Sponsor: Per Torp Sangild
Recruiting --> Completed Phase classification: P=N/A --> P1/2 | Trial primary completion date: Jun 2015 --> Jun 2016
- ||| chlorhexidine gluconate / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: Multicenter Blood Culture Quality Improvement (clinicaltrials.gov) - Jun 4, 2015
P=N/A, N=14889, Completed, Sponsor: Vanderbilt University
Phase classification: P=N/A --> P1/2 | Trial primary completion date: Jun 2015 --> Jun 2016 Active, not recruiting --> Completed | N=33000 --> 14889 | Trial primary completion date: Dec 2013 --> Mar 2013
- Enrollment change, Trial withdrawal: ToPICL: Topical Antibiotics for Prevention of Intensive Care Unit (ICU) Central Line Infections (clinicaltrials.gov) - May 29, 2015
P=N/A, N=0, Withdrawn, Sponsor: Fraser Health
Active, not recruiting --> Completed | N=33000 --> 14889 | Trial primary completion date: Dec 2013 --> Mar 2013 N=140 --> 0 | Terminated --> Withdrawn
- amoxicillin / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures (clinicaltrials.gov) - May 27, 2015
P=N/A, N=266, Completed, Sponsor: University of Santiago de Compostela
N=140 --> 0 | Terminated --> Withdrawn Recruiting --> Completed | N=200 --> 266 | Trial primary completion date: Sep 2014 --> Apr 2015
- Trial completion: Effect of Different Strategies for Titrating a High MAP on Microcirculation (clinicaltrials.gov) - May 27, 2015
P4, N=20, Completed, Sponsor: Southeast University, China
Recruiting --> Completed | N=200 --> 266 | Trial primary completion date: Sep 2014 --> Apr 2015 Recruiting --> Completed
- Trial completion, Trial primary completion date: Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants (clinicaltrials.gov) - May 27, 2015
P2, N=211, Completed, Sponsor: University of Rhode Island
Recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Jun 2012 --> Mar 2014
- dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine on Microcirculation in Septic Shock (clinicaltrials.gov) - May 22, 2015
P4, N=26, Completed, Sponsor: Southeast University, China
Active, not recruiting --> Completed | Trial primary completion date: Jun 2012 --> Mar 2014 Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Apr 2015
- Enrollment open, Trial initiation date, Trial primary completion date: Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study (clinicaltrials.gov) - May 20, 2015
P=N/A, N=40, Recruiting, Sponsor: Karl-Andre Wian
Recruiting --> Completed | Trial primary completion date: Oct 2015 --> Apr 2015 Not yet recruiting --> Recruiting | Initiation date: Sep 2014 --> Feb 2015 | Trial primary completion date: Sep 2015 --> Mar 2016
- Trial completion, Enrollment change: BIOVISION: Bioimpedance Analysis in Septic Intensive Care Unit (ICU) Patients (clinicaltrials.gov) - May 20, 2015
P=N/A, N=55, Completed, Sponsor: St. Joseph's Healthcare Hamilton
Not yet recruiting --> Recruiting | Initiation date: Sep 2014 --> Feb 2015 | Trial primary completion date: Sep 2015 --> Mar 2016 Recruiting --> Completed | N=100 --> 55
- | Enrollment closed, Trial primary completion date: VANCS II: Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients (clinicaltrials.gov) - May 20, 2015
P3, N=250, Active, not recruiting, Sponsor: Instituto do Cancer do Estado de S
Recruiting --> Completed | N=100 --> 55 Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2013 --> Mar 2014
- Trial completion, IO biomarker: Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1? (clinicaltrials.gov) - May 20, 2015
P1/2, N=30, Completed, Sponsor: Radboud University
Recruiting --> Active, not recruiting | Trial primary completion date: Nov 2013 --> Mar 2014 Recruiting --> Completed
- Trial completion, Trial primary completion date: Effects of BCG on Immune Response (clinicaltrials.gov) - May 13, 2015
P2/3, N=20, Completed, Sponsor: Radboud University
Recruiting --> Completed Not yet recruiting --> Completed | Trial primary completion date: May 2014 --> Oct 2014
- Enrollment closed: Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis (clinicaltrials.gov) - May 12, 2015
P=N/A, N=1, Active, not recruiting, Sponsor: Chinese PLA General Hospital
Not yet recruiting --> Completed | Trial primary completion date: May 2014 --> Oct 2014 Recruiting --> Active, not recruiting
- |||||| Prezista (darunavir) / J&J, Isentress (raltegravir) / Merck (MSD)
Enrollment open: Management of Participants With Low-level Persistent Viremia (ANRS 161 L-VIR) (clinicaltrials.gov) - May 12, 2015
P3, N=120, Recruiting, Sponsor: French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- azithromycin / Generic mfg.
Trial termination, IO biomarker, Immunomodulating: Efficacy of Macrolide Immunomodulation in Severe Sepsis. (clinicaltrials.gov) - May 5, 2015
P2, N=100, Terminated, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Suspended --> Terminated; Safety evaluation due to recent publications.
- Trial primary completion date, Surgery: Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2 (clinicaltrials.gov) - May 4, 2015
P=N/A, N=330, Recruiting, Sponsor: University of Michigan
Suspended --> Terminated; Safety evaluation due to recent publications. Trial primary completion date: Mar 2015 --> Sep 2015
- Trial completion, Trial primary completion date: Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome (clinicaltrials.gov) - May 4, 2015
P1/2, N=350, Completed, Sponsor: Jinhua Central Hospital
Trial primary completion date: Mar 2015 --> Sep 2015 Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Jun 2014
- Trial completion, Enrollment change, Trial primary completion date: Inflammatory Cytokine Quantification in Infants (clinicaltrials.gov) - May 4, 2015
P=N/A, N=21, Completed, Sponsor: University of Utah
Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Jun 2014 Recruiting --> Completed | N=60 --> 21 | Trial primary completion date: Jun 2014 --> May 2013
- levofloxacin / Generic mfg., cloxacillin / Generic mfg.
Trial completion, Enrollment change: Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus. (clinicaltrials.gov) - May 1, 2015
P3, N=1, Completed, Sponsor: Fundaci
Recruiting --> Completed | N=60 --> 21 | Trial primary completion date: Jun 2014 --> May 2013 Recruiting --> Completed | N=154 --> 1
- Enrollment open: DYnAMICS: DYsphAgia In Mechanically Ventilated ICU patientS (clinicaltrials.gov) - Apr 30, 2015
P=N/A, N=2000, Recruiting, Sponsor: University Hospital Inselspital, Berne
Recruiting --> Completed | N=154 --> 1 Not yet recruiting --> Recruiting
- Trial primary completion date: VISLISI: Virulence of Staphylococcus Lugdunensis in Severe Infections (clinicaltrials.gov) - Apr 25, 2015
P=N/A, N=82, Recruiting, Sponsor: University Hospital, Strasbourg, France
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2016 --> Sep 2018
- | Trial initiation date: De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis (clinicaltrials.gov) - Apr 21, 2015
P3, N=120, Completed, Sponsor: Assistance Publique Hopitaux De Marseille
Trial primary completion date: Dec 2016 --> Sep 2018 Initiation date: Oct 2011 --> Feb 2012
- Biomarker, Trial completion, Enrollment change: Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis? (clinicaltrials.gov) - Apr 21, 2015
P=N/A, N=21, Completed, Sponsor: Sygehus Lillebaelt
Initiation date: Oct 2011 --> Feb 2012 Recruiting --> Completed | N=40 --> 21
- ||| Enrollment closed, Trial primary completion date: Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IV (clinicaltrials.gov) - Apr 20, 2015
P4, N=214, Active, not recruiting, Sponsor: Pfizer
Recruiting --> Completed | N=40 --> 21 Completed --> Active, not recruiting | Trial primary completion date: Mar 2014 --> Sep 2015
- ||| hydrocortisone / Generic mfg.
Trial completion: Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Apr 20, 2015
P=N/A, N=197, Completed, Sponsor: Mahidol University
Completed --> Active, not recruiting | Trial primary completion date: Mar 2014 --> Sep 2015 Recruiting --> Completed
- | Enrollment change, Trial primary completion date: NOMS: Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal (clinicaltrials.gov) - Apr 16, 2015
P3, N=29260, Recruiting, Sponsor: Johns Hopkins Bloomberg School of Public Health
Recruiting --> Completed N=10000 --> 29260 | Trial primary completion date: Feb 2014 --> Dec 2016
- ||| Enrollment change, Gram negative: GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults (clinicaltrials.gov) - Apr 15, 2015
P2, N=1415, Completed, Sponsor: GlaxoSmithKline
N=10000 --> 29260 | Trial primary completion date: Feb 2014 --> Dec 2016 N=1890 --> 1415
- || Trial primary completion date: Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=5308, Recruiting, Sponsor: Magnolia Medical Technologies, Inc.
N=1890 --> 1415 Trial primary completion date: Dec 2014 --> Dec 2015
- || Trial primary completion date: Study to Evaluate the Effectiveness of the Initial Specimen Diversion Device When Collected Through Peripheral Intravenous Catheters (clinicaltrials.gov) - Apr 15, 2015
P=N/A, N=4444, Recruiting, Sponsor: Magnolia Medical Technologies, Inc.
Trial primary completion date: Dec 2014 --> Dec 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- Biomarker, Trial completion: Biomarker Analysis of Stress (clinicaltrials.gov) - Apr 14, 2015
P=N/A, N=50, Completed, Sponsor: National Institute of Environmental Health Sciences (NIEHS)
Trial primary completion date: Dec 2014 --> Dec 2015 Not yet recruiting --> Completed
- Trial primary completion date: A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis (clinicaltrials.gov) - Apr 14, 2015
P1, N=50, Recruiting, Sponsor: Mansoura University Children Hospital
Not yet recruiting --> Completed Trial primary completion date: Jan 2015 --> Apr 2015