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55 Companies |
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51 Products |
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51 Products |
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62 Mechanisms of Action |
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0 Trials |
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1119 News |
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- || New P3 trial: IDEAL-ICU: I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit) (clinicaltrials.gov) - Sep 9, 2012
P3, N=824, Recruiting, Sponsor: Centre Hospitalier Universitaire Dijon
- Trial completion: NEOLACTO: Pilot Study: Lactoferrin for Prevention of Neonatal Sepsis (clinicaltrials.gov) - Sep 6, 2012
P2, N=190, Completed, Sponsor: Universidad Peruana Cayetano Heredia
Active, not recruiting --> Completed
- Trial completion: Pleconaril Enteroviral Sepsis Syndrome (clinicaltrials.gov) - Sep 5, 2012
P2, N=61, Completed, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Active, not recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Taurolidine Lock Solution in the Prevention of Catheter Related Bacteremia (clinicaltrials.gov) - Sep 3, 2012
P3, N=129, Completed, Sponsor: Aarhus University Hospital
Active, not recruiting --> Completed Recruiting --> Completed
- | doripenem / Generic mfg.
Enrollment change: Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients (clinicaltrials.gov) - Aug 24, 2012
P4, N=30, Completed, Sponsor: Emory University
Recruiting --> Completed N=50 --> 30
- | doripenem / Generic mfg.
Trial completion: Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients (clinicaltrials.gov) - Aug 24, 2012
P4, N=30, Completed, Sponsor: Emory University
N=50 --> 30 Recruiting --> Completed
- Trial initiation date: SEREAL: Selenium Replacement and Serum Selenium Level in Severe Sepsis and Septic Shock Patients (clinicaltrials.gov) - Aug 22, 2012
P2, N=294, Not yet recruiting, Sponsor: Gil Joon Suh
Recruiting --> Completed Initiation date: May 2012 --> Sep 2012
- piperacillin sodium/tazobactam sodium / Generic mfg.
Enrollment closed: Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase (clinicaltrials.gov) - Aug 22, 2012
P=N/A, N=1000, Active, not recruiting, Sponsor: University of Pittsburgh
Initiation date: May 2012 --> Sep 2012 Recruiting --> Active, not recruiting
- Enrollment closed, Gram negative: Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin (clinicaltrials.gov) - Aug 22, 2012
P=N/A, N=1000, Active, not recruiting, Sponsor: University of Pittsburgh
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- Enrollment change, Intubation: Effects of Tracheal Intubation on Ventilation With a Laryngeal Mask During Percutaneous Dilatation Tracheostomy (clinicaltrials.gov) - Aug 20, 2012
P=N/A, N=60, Completed, Sponsor: University of Padova
Recruiting --> Active, not recruiting N=30 --> 60
- ||| ciprofloxacin (Q3939) / Bayer, Novartis
Clinical: Assessment of the Safety and Efficacy of Ciproxan-I.V. in Daily Clinical Practice - Analysis Results From a Post-marketing Surveillance (clinicaltrials.gov) - Aug 20, 2012
P=N/A, N=3274, Completed, Sponsor: Bayer
- Trial completion, Intubation: Effects of Tracheal Intubation on Ventilation With a Laryngeal Mask During Percutaneous Dilatation Tracheostomy (clinicaltrials.gov) - Aug 20, 2012
P=N/A, N=60, Completed, Sponsor: University of Padova
N=30 --> 60 Recruiting --> Completed
- Clinical: Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis) (clinicaltrials.gov) - Aug 16, 2012
P=N/A, N=60, Recruiting, Sponsor: University Hospital, Grenoble
- Clinical: MedIso: The Utility of Multiplex PCR for Detection of DNA in Neutropenic Patients With Hematological Malignancies (clinicaltrials.gov) - Aug 16, 2012
P=N/A, N=84, Completed, Sponsor: Centre Hospitalier Universitaire Vaudois
- Enrollment open: Comparison of Ultrasound-guided Versus Blind Insertion of Radial Artery Catheters (clinicaltrials.gov) - Aug 13, 2012
P=N/A, N=214, Recruiting, Sponsor: Yale University
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Perinatal Outcome After Premature Rupture of Membranes (clinicaltrials.gov) - Aug 12, 2012
P=N/A, N=80, Completed, Sponsor: Saint Thomas Hospital, Panama
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial termination: Ethanol Locks for the Treatment of Central Venous Line Infections (clinicaltrials.gov) - Aug 2, 2012
P3, N=11, Terminated, Sponsor: Baystate Medical Center
Recruiting --> Completed Recruiting --> Terminated; inability to enroll adequate number of patients
- Enrollment change: Ethanol Locks for the Treatment of Central Venous Line Infections (clinicaltrials.gov) - Aug 2, 2012
P3, N=11, Terminated, Sponsor: Baystate Medical Center
Recruiting --> Terminated; inability to enroll adequate number of patients N=82 --> 11
- Trial termination: Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis (clinicaltrials.gov) - Jul 31, 2012
P=N/A, N=57, Terminated, Sponsor: Tel-Aviv Sourasky Medical Center
Active, not recruiting --> Terminated; Difficulty in recruitment. Mothers of infants preferred to take probiotics bought over-the-counter over the possibility of being in a placebo group
- Enrollment change: Probiotic Administartion to Mothers of Preterm Infants to Prevent Necrotizing Enterocolitis and Sepsis (clinicaltrials.gov) - Jul 31, 2012
P=N/A, N=57, Terminated, Sponsor: Tel-Aviv Sourasky Medical Center
Mothers of infants preferred to take probiotics bought over-the-counter over the possibility of being in a placebo group N=80 --> 57
- Surgery: Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery (clinicaltrials.gov) - Jul 29, 2012
P=N/A, N=250, Recruiting, Sponsor: University Hospital, Geneva
- | Leukine (sargramostim) / Partner Therap
New P1/2 trial: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) - Jul 29, 2012
P1/2, N=92, Not yet recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
- Enrollment change: Early Warning System for Clinical Deterioration on General Hospital Wards (clinicaltrials.gov) - Jul 24, 2012
P=N/A, N=20031, Completed, Sponsor: Tom Bailey, MD
N=80 --> 57 N=7300 --> 20031
- Trial completion: Early Warning System for Clinical Deterioration on General Hospital Wards (clinicaltrials.gov) - Jul 24, 2012
P=N/A, N=20031, Completed, Sponsor: Tom Bailey, MD
N=7300 --> 20031 Recruiting --> Completed
- Clinical: Sepsis Metabolomics (clinicaltrials.gov) - Jul 23, 2012
P=N/A, N=65, Completed, Sponsor: Chinese PLA General Hospital
- Actimmune (interferon gamma-1 b) / Clinigen, Amgen
New P3 trial, IO biomarker: The Effects of Interferon-gamma on Sepsis-induced Immunoparalysis (clinicaltrials.gov) - Jul 23, 2012
P3, N=20, Recruiting, Sponsor: Radboud University
- Clinical: Lactate Metabolism After an Endotoxin Challenge in Healthy Humans (clinicaltrials.gov) - Jul 22, 2012
P=N/A, N=14, Completed, Sponsor: University of Lausanne
- | Fragmin (dalteparin sodium) / Pfizer, Eisai
New P2 trial: Heparin Anticoagulation to Improve Outcomes in Septic Shock: The HALO Pilot (clinicaltrials.gov) - Jul 22, 2012
P2, N=76, Active, not recruiting, Sponsor: University of Manitoba
- Betadine (povidone iodine) / Egis
New P4 trial: PJB 1: PVP Iodine Effect on Post Debridement Bacteraemia (clinicaltrials.gov) - Jul 19, 2012
P4, N=20, Completed, Sponsor: University of Zurich
- Surgery: Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery (clinicaltrials.gov) - Jul 18, 2012
P=N/A, N=30, Recruiting, Sponsor: University Hospital, Geneva
- meropenem / Generic mfg.
Trial completion: MERO001: A Study of Meropenem Standard 30 Minute Infusion Versus Prolonged 3 Hour Infusion in Intensive Care Unit (ICU) Patients (clinicaltrials.gov) - Jul 18, 2012
P=N/A, N=10, Completed, Sponsor: Austin Health
Recruiting --> Completed Recruiting --> Completed
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Enrollment open: ADRENAL: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (clinicaltrials.gov) - Jul 7, 2012
P4, N=3800, Recruiting, Sponsor: The George Institute
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial termination: COMPACT - COMbining Plasma-filtration and Adsorption Clinical Trial (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=184, Terminated, Sponsor: Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva
Not yet recruiting --> Recruiting Suspended --> Terminated; The study was prematurely interrupted for futility.
- Enrollment change: COMPACT - COMbining Plasma-filtration and Adsorption Clinical Trial (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=184, Terminated, Sponsor: Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva
Suspended --> Terminated; The study was prematurely interrupted for futility. N=330 --> 184
- Clinical: Vitamin D and Critically Ill Patients (clinicaltrials.gov) - Jul 4, 2012
P=N/A, N=234, Completed, Sponsor: Chinese PLA General Hospital
- || ampicillin / Generic mfg., gentamicin sulfate / Generic mfg.
New P2/3 trial: Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term (clinicaltrials.gov) - Jul 2, 2012
P2/3, N=161, Completed, Sponsor: Hospital de Santa Maria, Portugal
- Biomarker, Enrollment change: Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections (clinicaltrials.gov) - Jun 29, 2012
P=N/A, N=94, Completed, Sponsor: Federal University of Minas Gerais
N=330 --> 184 N=124 --> 94
- Biomarker, Trial completion: Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections (clinicaltrials.gov) - Jun 29, 2012
P=N/A, N=94, Completed, Sponsor: Federal University of Minas Gerais
N=124 --> 94 Recruiting --> Completed
- Ventavis (iloprost) / Bayer, J&J, University of Copenhagen, Integrilin (eptifibatide) / Takeda
Trial initiation date: Integrilin and Ilomedin in Combination in Comparison to Standard Treatment in Severe Pneumonia Patients With Severe Sepsis (clinicaltrials.gov) - Jun 24, 2012
P2, N=36, Suspended, Sponsor: Thrombologic ApS
Recruiting --> Completed Initiation date: Feb 2012 --> Jun 2012
- || New P3 trial: De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis (clinicaltrials.gov) - Jun 21, 2012
P3, N=120, Recruiting, Sponsor: Assistance Publique Hopitaux De Marseille
- Turnobi (L-citrulline intravenous) / Asklepion Pharma
Trial initiation date: Citrulline in Severe Sepsis (clinicaltrials.gov) - Jun 18, 2012
P2, N=75, Recruiting, Sponsor: Vanderbilt University
Initiation date: Feb 2012 --> Jun 2012 Initiation date: Jan 2012 --> Aug 2012
- Trial initiation date: HYSATESS-p: Hypertonic Saline and Terlipressin for Sepsis-associated Hypotension (clinicaltrials.gov) - Jun 18, 2012
P3, N=21, Terminated, Sponsor: Hospital General de Ciudad Real
Initiation date: Jan 2012 --> Aug 2012 Initiation date: Mar 2011 --> Jun 2012
- Clinical: UARK 2009-99 A Non-interventional Observational Study of Infectious Complications in Cancer Patients (clinicaltrials.gov) - Jun 17, 2012
P=N/A, N=600, Recruiting, Sponsor: University of Arkansas
- acyclovir / Generic mfg.
Trial completion: A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo) (clinicaltrials.gov) - Jun 17, 2012
P1, N=32, Completed, Sponsor: Phillip Brian Smith
Initiation date: Mar 2011 --> Jun 2012 Recruiting --> Completed
- ||||| leflunomide / Generic mfg.
New P2 trial: An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria (clinicaltrials.gov) - Jun 13, 2012
P2, N=60, Recruiting, Sponsor: Changzheng-Cinkate
- Clinical: Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock (clinicaltrials.gov) - Jun 11, 2012
P=N/A, N=16, Completed, Sponsor: Casa de Saúde São José
- Enrollment closed: Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants (clinicaltrials.gov) - Jun 11, 2012
P2, N=212, Active, not recruiting, Sponsor: University of Rhode Island
Recruiting --> Completed Recruiting --> Active, not recruiting
- | New P2 trial: Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic Shock (clinicaltrials.gov) - Jun 4, 2012
P2, N=31, Completed, Sponsor: Ferring Pharmaceuticals
- Clinical: Red Blood Cell Transfusion Improves Perfusion Parameters in Septic Shock Patients With Hypoperfusion (clinicaltrials.gov) - Jun 3, 2012
P=N/A, N=46, Completed, Sponsor: Bruno Franco Mazza
- heparin sodium injection / Generic mfg.
Enrollment open: Safety of Heparin in Patients With Septic Shock (clinicaltrials.gov) - May 29, 2012
P2, N=100, Recruiting, Sponsor: University of Colorado, Denver
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting