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53 Companies |
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51 Products |
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51 Products |
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62 Mechanisms of Action |
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0 Trials |
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1105 News |
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- clonidine / Generic mfg.
New P2/3 trial: CATACHOC: Upregulation of Alpha-1 Receptors Upon Septic Shock? (clinicaltrials.gov) - May 15, 2013
P2/3, N=40, Recruiting, Sponsor: Direction Centrale du Service de Sant
- Trial completion: DAMSEL1: Melatonin in Healthy Volunteers (clinicaltrials.gov) - May 6, 2013
P1, N=20, Completed, Sponsor: University of Aberdeen
Recruiting --> Completed
- Biomarker: HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis (clinicaltrials.gov) - May 2, 2013
P=N/A, N=118, Completed, Sponsor: Changhai Hospital
- | Trial termination: GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock (clinicaltrials.gov) - Apr 28, 2013
P3, N=214, Terminated, Sponsor: Green Cross Corporation
Recruiting --> Completed Suspended --> Terminated
- ||| Enrollment open: EMOS: Procurement of Human Specimens for the Evaluation of Early Markers of Sepsis (clinicaltrials.gov) - Apr 28, 2013
P=N/A, N=1200, Recruiting, Sponsor: Abbott Diagnostics Division
Suspended --> Terminated Not yet recruiting --> Recruiting
- azithromycin / Generic mfg.
Trial suspension, IO biomarker, Immunomodulating: Efficacy of Macrolide Immunomodulation in Severe Sepsis. (clinicaltrials.gov) - Apr 16, 2013
P2, N=100, Suspended, Sponsor: Department of Veterans Affairs
Not yet recruiting --> Recruiting Recruiting --> Suspended
- Trial completion: Probiotic Sport Study (clinicaltrials.gov) - Apr 8, 2013
P=N/A, N=24, Completed, Sponsor: Green Beat
Recruiting --> Suspended Recruiting --> Completed
- ||||||| Trial completion: Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock (clinicaltrials.gov) - Apr 8, 2013
P3, N=60, Completed, Sponsor: Gambro Lundia AB
Recruiting --> Completed Active, not recruiting --> Completed
- Trial initiation date: CANDIPOP: Prospective Population Study on Candidemia in Spain (clinicaltrials.gov) - Apr 2, 2013
P=N/A, N=730, Completed, Sponsor: Fundacion SEIMC-GESIDA
Active, not recruiting --> Completed Initiation date: May 2012 --> Mar 2013
- Enrollment change: CANDIPOP: Prospective Population Study on Candidemia in Spain (clinicaltrials.gov) - Apr 2, 2013
P=N/A, N=730, Completed, Sponsor: Fundacion SEIMC-GESIDA
Initiation date: May 2012 --> Mar 2013 N=500 --> 730
- Trial completion: CANDIPOP: Prospective Population Study on Candidemia in Spain (clinicaltrials.gov) - Apr 2, 2013
P=N/A, N=730, Completed, Sponsor: Fundacion SEIMC-GESIDA
N=500 --> 730 Not yet recruiting --> Completed
- Trial completion: HeRO: Impact of Heart Rate Characteristics Monitoring in Neonates (clinicaltrials.gov) - Mar 31, 2013
P=N/A, N=3003, Completed, Sponsor: University of Virginia
Not yet recruiting --> Completed Active, not recruiting --> Completed
- || New P3 trial: Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients (clinicaltrials.gov) - Mar 27, 2013
P3, N=212, Terminated, Sponsor: Maastricht University Medical Center
- Trial termination: Muscle Atrophy in Patients With Severe Sepsis (clinicaltrials.gov) - Mar 20, 2013
P=N/A, N=25, Terminated, Sponsor: Ohio State University
Active, not recruiting --> Completed Recruiting --> Terminated; slow accrual made study completion unfeasible
- Enrollment change: Muscle Atrophy in Patients With Severe Sepsis (clinicaltrials.gov) - Mar 20, 2013
P=N/A, N=25, Terminated, Sponsor: Ohio State University
Recruiting --> Terminated; slow accrual made study completion unfeasible N=87 --> 25
- Trial completion: Incidence of Bacteremia Following Argon Plasma Coagulation in Patients With Endobronchial Lesions (clinicaltrials.gov) - Mar 11, 2013
P=N/A, N=46, Completed, Sponsor: Meir Medical Center
N=87 --> 25 Recruiting --> Completed
- ||| ALT 836 / ImmunityBio
Enrollment closed: Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Mar 10, 2013
P2, N=150, Active, not recruiting, Sponsor: Altor Bioscience Corporation
Recruiting --> Completed Completed --> Active, not recruiting
- Trial termination: Nutrilock: Effect of Taurolidin on Prevention of Bloodstream Infection (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=39, Terminated, Sponsor: University Hospital, Rouen
Completed --> Active, not recruiting Recruiting --> Terminated; lack of recruitment
- Enrollment change: Nutrilock: Effect of Taurolidin on Prevention of Bloodstream Infection (clinicaltrials.gov) - Mar 3, 2013
P=N/A, N=39, Terminated, Sponsor: University Hospital, Rouen
Recruiting --> Terminated; lack of recruitment N=88 --> 39
- Enrollment open: Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture. (clinicaltrials.gov) - Mar 3, 2013
P4, N=200, Recruiting, Sponsor: Instituto do Coracao
N=88 --> 39 Not yet recruiting --> Recruiting
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Enrollment change: The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers (clinicaltrials.gov) - Feb 27, 2013
P1, N=12, Completed, Sponsor: University of Medicine and Dentistry New Jersey
Not yet recruiting --> Recruiting N=24 --> 12
- IO biomarker: Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients (clinicaltrials.gov) - Feb 27, 2013
P=N/A, N=1, Recruiting, Sponsor: Chinese PLA General Hospital
- Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion: The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers (clinicaltrials.gov) - Feb 27, 2013
P1, N=12, Completed, Sponsor: University of Medicine and Dentistry New Jersey
N=24 --> 12 Active, not recruiting --> Completed
- || New P3 trial: Different Modes of Temperature Measurement in the Emergency Department (clinicaltrials.gov) - Feb 26, 2013
P3, N=500, Not yet recruiting, Sponsor: HaEmek Medical Center, Israel
- Enrollment change: EARTH-ICU: Early Physical Therapy in Patients With Sepsis (clinicaltrials.gov) - Feb 24, 2013
P=N/A, N=36, Recruiting, Sponsor: Cliniques universitaires Saint-Luc- Universit
Active, not recruiting --> Completed N=22 --> 36
- Enrollment open: EARTH-ICU: Early Physical Therapy in Patients With Sepsis (clinicaltrials.gov) - Feb 24, 2013
P=N/A, N=36, Recruiting, Sponsor: Cliniques universitaires Saint-Luc- Universit
N=22 --> 36 Not yet recruiting --> Recruiting
- Zeftera (ceftobiprole) / Basilea
Enrollment change: Ceftobiprole in the Treatment of Hospitalized Patients With Staphylococcus Aureus Bacteremia (clinicaltrials.gov) - Feb 18, 2013
P2, N=0, Withdrawn, Sponsor: Basilea Pharmaceutica
Not yet recruiting --> Recruiting N=45 --> 0
- Enrollment open: Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to Extended-spectrum Beta-lactamase (ESBL) or Carbapenemase-producing Enterobacteriaceae: an Observational Multinational Study (clinicaltrials.gov) - Feb 15, 2013
P=N/A, N=2000, Recruiting, Sponsor: JESUS RODRIGUEZ BA
N=45 --> 0 Not yet recruiting --> Recruiting
- ||| Trial completion: Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients (clinicaltrials.gov) - Feb 14, 2013
P=N/A, N=300, Completed, Sponsor: The Cleveland Clinic
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- dexmedetomidine / Generic mfg.
Clinical: DESIRE: Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial (clinicaltrials.gov) - Feb 6, 2013
P4, N=200, Recruiting, Sponsor: Wakayama Medical University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- sevelamer carbonate / Generic mfg.
Trial completion: Sevelamer for Reducing Endotoxemia and Immune Activation (clinicaltrials.gov) - Feb 6, 2013
P2, N=40, Completed, Sponsor: AIDS Clinical Trials Group
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment change: BICUK: BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
Active, not recruiting --> Completed N=20 --> 51
- Enrollment change: NICUPS: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
N=20 --> 51 N=200 --> 51
- Enrollment closed: ACT-ICU Study: Activity and Cognitive Therapy in the Intensive Care Unit (clinicaltrials.gov) - Feb 4, 2013
P1, N=90, Active, not recruiting, Sponsor: Vanderbilt University
N=200 --> 51 Recruiting --> Active, not recruiting
- Trial completion: BICUK: BK Virus and Renal Dysfunction in Postoperative/Posttraumatic Critically Ill Patients (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial completion: NICUPS: NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock (clinicaltrials.gov) - Feb 4, 2013
P=N/A, N=51, Completed, Sponsor: University of Ulm
Recruiting --> Completed Recruiting --> Completed
- Enrollment open: Hepcidin Levels in Preterm Infants (clinicaltrials.gov) - Jan 27, 2013
P=N/A, N=50, Recruiting, Sponsor: Meir Medical Center
Recruiting --> Completed Not yet recruiting --> Recruiting
- Recomodulin (recombinant thrombomodulin alfa) / Asahi Kasei
Trial withdrawal: Study to Look at the Effects of ART-123 on Patients With Sepsis and Disseminated Intravascular Coagulation (DIC) (clinicaltrials.gov) - Jan 22, 2013
P2b, N=0, Withdrawn, Sponsor: University of South Alabama
Not yet recruiting --> Recruiting Completed --> Withdrawn
- esmolol / Generic mfg.
Enrollment change: Heart Rate Control With Esmolol in Septic Shock (clinicaltrials.gov) - Jan 22, 2013
P2, N=154, Completed, Sponsor: Andrea Morelli
Completed --> Withdrawn N=100 --> 154
- Clinical: Dose-response Study of Arginine Supplementation in Severe Sepsis (clinicaltrials.gov) - Jan 22, 2013
P0, N=8, Completed, Sponsor: Maastricht University Medical Center
- esmolol / Generic mfg.
Trial completion: Heart Rate Control With Esmolol in Septic Shock (clinicaltrials.gov) - Jan 22, 2013
P2, N=154, Completed, Sponsor: Andrea Morelli
N=100 --> 154 Recruiting --> Completed
- || Mycamine (micafungin) / Astellas
New P3 trial: EMPIRICUS: Empirical Antifungal Treatment in ICUS (clinicaltrials.gov) - Jan 21, 2013
P3, N=260, Recruiting, Sponsor: University Hospital, Grenoble
- Enrollment closed: Early-Onset Sepsis Surveillance Study (clinicaltrials.gov) - Jan 16, 2013
P=N/A, N=615, Active, not recruiting, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting --> Completed Completed --> Active, not recruiting
- Enrollment change: Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability (clinicaltrials.gov) - Jan 14, 2013
P=N/A, N=0, Withdrawn, Sponsor: Duke University
Completed --> Active, not recruiting N=10000 --> 0
- New P3 trial: VECTORII: In Vivo Effects of C1-esterase Inhibitor on the Innate Immune Response During Human Endotoxemia - VECTOR II (clinicaltrials.gov) - Jan 9, 2013
P3, N=20, Not yet recruiting, Sponsor: Radboud University
- Enrollment open, Gram negative: Duration of Antibiotics for the Treatment of Gram-negative Bacilli Bacteremia (clinicaltrials.gov) - Jan 5, 2013
P=N/A, N=400, Recruiting, Sponsor: Rabin Medical Center
N=10000 --> 0 Not yet recruiting --> Recruiting
- | dexmedetomidine / Generic mfg.
Clinical: DESIRE: Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial (clinicaltrials.gov) - Jan 2, 2013
P4, N=200, Recruiting, Sponsor: Wakayama Medical University
- ||||||| eritoran (E5564) / Eisai
Trial completion: ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis (clinicaltrials.gov) - Jan 1, 2013
P3, N=2000, Completed, Sponsor: Eisai Inc.
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- || Enrollment change: A Laboratory-based Surveillance Study of Candida Bloodstream Infections (MK-0991-093) (clinicaltrials.gov) - Dec 27, 2012
P=N/A, N=436, Completed, Sponsor: Merck Sharp & Dohme Corp.
Active, not recruiting --> Completed N=1000 --> 436
- ||| Trial completion: A Laboratory-based Surveillance Study of Candida Bloodstream Infections (MK-0991-093) (clinicaltrials.gov) - Dec 27, 2012
P=N/A, N=436, Completed, Sponsor: Merck Sharp & Dohme Corp.
N=1000 --> 436 Recruiting --> Completed