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55 Companies |
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51 Products |
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51 Products |
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62 Mechanisms of Action |
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0 Trials |
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1119 News |
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- paracetamol / Generic mfg.
Trial completion: ACROSS: Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis (clinicaltrials.gov) - Dec 20, 2013
P2a, N=51, Completed, Sponsor: Vanderbilt University
Recruiting --> Completed
- Betadine (povidone iodine) / Egis
Trial completion: PJB 1: PVP Iodine Effect on Post Debridement Bacteraemia (clinicaltrials.gov) - Dec 19, 2013
P4, N=20, Completed, Sponsor: University of Zurich
Recruiting --> Completed Not yet recruiting --> Completed
- || Trial initiation date: Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study) (clinicaltrials.gov) - Dec 17, 2013
P=N/A, N=1500, Recruiting, Sponsor: T2 Biosystems
Not yet recruiting --> Completed Initiation date: Apr 2013 --> Jul 2013
- Enrollment change: Improving Maternal and Child Health in India: Evaluating Demand and Supply Side Strategies (IMATCHINE) (clinicaltrials.gov) - Dec 17, 2013
P=N/A, N=14990, Recruiting, Sponsor: Duke University
Initiation date: Apr 2013 --> Jul 2013 N=36600 --> 14990
- ||| Enrollment open: Detecting Infections Rapidly and Easily for Bacteremia Trial (DIREBT) (clinicaltrials.gov) - Dec 17, 2013
P=N/A, N=700, Recruiting, Sponsor: T2 Biosystems
N=36600 --> 14990 Not yet recruiting --> Recruiting
- ||| Enrollment open: Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study) (clinicaltrials.gov) - Dec 17, 2013
P=N/A, N=1500, Recruiting, Sponsor: T2 Biosystems
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||||| Trial completion: ABDO-MIX: Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock (clinicaltrials.gov) - Dec 16, 2013
P3, N=243, Completed, Sponsor: Meditor SAS
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- Enrollment open: A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka (clinicaltrials.gov) - Dec 15, 2013
P=N/A, N=7883, Enrolling by invitation, Sponsor: Harvard School of Public Health
Active, not recruiting --> Completed Not yet recruiting --> Enrolling by invitation
- Enrollment open, Monotherapy, Head-to-Head: Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit (clinicaltrials.gov) - Dec 15, 2013
P=N/A, N=84, Recruiting, Sponsor: Institute of Liver and Biliary Sciences, India
Not yet recruiting --> Enrolling by invitation Not yet recruiting --> Recruiting
- Turnobi (L-citrulline intravenous) / Asklepion Pharma
Enrollment open: Citrulline in Severe Sepsis (clinicaltrials.gov) - Dec 15, 2013
P2, N=75, Recruiting, Sponsor: Vanderbilt University
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- | Enrollment closed: SIS Multicenter Study of Duration of Antibiotics for Intraabdominal Infection (clinicaltrials.gov) - Dec 9, 2013
P3, N=1120, Active, not recruiting, Sponsor: National Institute of General Medical Sciences (NIGMS)
Not yet recruiting --> Recruiting Recruiting --> Active, not recruiting
- Trial completion, Immune cell: Immune-cell Membrane Trafficking (clinicaltrials.gov) - Dec 9, 2013
P=N/A, N=213, Completed, Sponsor: University of Washington
Recruiting --> Active, not recruiting Recruiting --> Completed
- Enrollment open: Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients (clinicaltrials.gov) - Dec 8, 2013
P=N/A, N=50, Recruiting, Sponsor: University of Michigan
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment change: Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study) (clinicaltrials.gov) - Dec 5, 2013
P=N/A, N=16, Completed, Sponsor: University of Manitoba
Not yet recruiting --> Recruiting N=20 --> 16
- Trial completion: Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study) (clinicaltrials.gov) - Dec 5, 2013
P=N/A, N=16, Completed, Sponsor: University of Manitoba
N=20 --> 16 Recruiting --> Completed
- Enrollment change: Effectiveness of Routine Sterile Gloving in Blood Culture (clinicaltrials.gov) - Dec 2, 2013
P=N/A, N=1854, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed N=3000 --> 1854
- Trial completion: Prospective Study of the Risk of Bacteremia in Directed Cholangioscopic Examination of the CBD (clinicaltrials.gov) - Nov 24, 2013
P=N/A, N=60, Completed, Sponsor: Texas Tech University Health Sciences Center
N=3000 --> 1854 Recruiting --> Completed
- Biomarker, Enrollment change: HSPA12B as a Potential Biomarker for Sepsis and Severe Sepsis (clinicaltrials.gov) - Nov 21, 2013
P=N/A, N=118, Completed, Sponsor: Changhai Hospital
Recruiting --> Completed N=87 --> 118
- Trial completion: Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution: A Pilot Study (clinicaltrials.gov) - Nov 21, 2013
P=N/A, N=40, Completed, Sponsor: University of Manitoba
N=87 --> 118 Active, not recruiting --> Completed
- Enrollment change: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
Active, not recruiting --> Completed N=100 --> 80
- Enrollment closed: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
N=100 --> 80 Recruiting --> Active, not recruiting
- ceftriaxone / Generic mfg.
Clinical: PHANTASi: Prehospital Antibiotics Against Sepsis Trial (clinicaltrials.gov) - Nov 18, 2013
P=N/A, N=2200, Not yet recruiting, Sponsor: VU University Medical Center
- acyclovir / Generic mfg.
Enrollment change: A Study to Describe the Pharmacokinetics of Acyclovir in Premature Infants (PTN_Acyclo) (clinicaltrials.gov) - Nov 18, 2013
P1, N=32, Completed, Sponsor: Phillip Brian Smith
Recruiting --> Active, not recruiting N=20 --> 32
- Trial completion: SEPSICOAG: Prospective Validation of Clini-biological Parameters Including Initial Hemostasis, Which Improve the Prediction of Death at 1 Month Among Patients With Septic Shock (clinicaltrials.gov) - Nov 14, 2013
P=N/A, N=780, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
N=20 --> 32 Recruiting --> Completed
- Enrollment open: International Multicentre Prevalence Study on Sepsis (clinicaltrials.gov) - Nov 13, 2013
P=N/A, N=1000, Recruiting, Sponsor: European Society of Intensive Care Medicine
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open: Intensive Care - GLObal Study on Severe Acute Respiratory Infection (clinicaltrials.gov) - Nov 13, 2013
P=N/A, N=4000, Recruiting, Sponsor: European Society of Intensive Care Medicine
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- ||||| Mycamine (micafungin) / Astellas
New P4 trial: A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or Candidemia (clinicaltrials.gov) - Nov 11, 2013
P4, N=109, Recruiting, Sponsor: Astellas Pharma China, Inc.
- ||| Enrollment open: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Nov 10, 2013
P=N/A, N=5000, Recruiting, Sponsor: Mayo Clinic
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- New P1/2 trial, IO biomarker: Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1? (clinicaltrials.gov) - Nov 5, 2013
P1/2, N=30, Recruiting, Sponsor: Radboud University
- piperacillin sodium/tazobactam sodium / Generic mfg., doripenem / Generic mfg.
Enrollment change: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients (clinicaltrials.gov) - Nov 4, 2013
P=N/A, N=50, Completed, Sponsor: University Hospital, Montpellier
Not yet recruiting --> Recruiting N=40 --> 50
- piperacillin sodium/tazobactam sodium / Generic mfg., doripenem / Generic mfg.
Trial completion: Pharmacokinetic of Doripenem and Piperacillin/Tazobactam in More Than 120 kg Critically Ill Patients (clinicaltrials.gov) - Nov 4, 2013
P=N/A, N=50, Completed, Sponsor: University Hospital, Montpellier
N=40 --> 50 Recruiting --> Completed
- clonidine / Generic mfg.
Trial initiation date: CATACHOC: Upregulation of Alpha-1 Receptors Upon Septic Shock? (clinicaltrials.gov) - Nov 3, 2013
P2/3, N=40, Recruiting, Sponsor: Direction Centrale du Service de Santé des Armées
Recruiting --> Completed Initiation date: Apr 2013 --> Aug 2013
- Cubicin (daptomycin) / Merck (MSD)
New P2b trial: Vancomycin Versus Daptomycin for the Treatment of Methicillin Resistant Staphylococcus Aureus (MRSA) Bacteremia (clinicaltrials.gov) - Nov 3, 2013
P2b, N=50, Recruiting, Sponsor: Singapore General Hospital
- | Enrollment open: HEMOSEPSIS: Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock (clinicaltrials.gov) - Oct 30, 2013
P3, N=153, Recruiting, Sponsor: University Hospital, Limoges
Initiation date: Apr 2013 --> Aug 2013 Not yet recruiting --> Recruiting
- New P3 trial: Pilot Study for the SQUEEZE Trial (clinicaltrials.gov) - Oct 30, 2013
P3, N=50, Recruiting, Sponsor: McMaster Children's Hospital
- Enrollment open, IO biomarker: Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1? (clinicaltrials.gov) - Oct 30, 2013
P1/2, N=30, Recruiting, Sponsor: Radboud University
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial completion: Early Haemodynamic Optimization Using Preload Dependence During Septic Shock = EHOSS-1 (clinicaltrials.gov) - Oct 29, 2013
P=N/A, N=61, Completed, Sponsor: Hospices Civils de Lyon
Not yet recruiting --> Recruiting Not yet recruiting --> Completed
- Trial completion: Expression and the Clinical Significance of Neutrophil PD-L1 During Sepsis (clinicaltrials.gov) - Oct 29, 2013
P=N/A, N=71, Completed, Sponsor: Changhai Hospital
Not yet recruiting --> Completed Not yet recruiting --> Completed
- Enrollment change: Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes? (clinicaltrials.gov) - Oct 28, 2013
P=N/A, N=100, Active, not recruiting, Sponsor: Jewish Hospital, Cincinnati, Ohio
Not yet recruiting --> Completed N=350 --> 100
- | Trial completion: NoSIRS: Effects of Transvenous Vagus Nerve Stimulation on Immune Response: a Pilot Study (clinicaltrials.gov) - Oct 28, 2013
P1, N=22, Completed, Sponsor: Medtronic Cardiac Rhythm Disease Management
N=350 --> 100 Recruiting --> Completed
- Review: Staphylococcus Aureus Bacteremia: Impact of an Intervention Program in Improving the Clinical Management and Review of the Clinical and Molecular Epidemiology (clinicaltrials.gov) - Oct 27, 2013
P=N/A, N=600, Completed, Sponsor: Fundación Pública Andaluza Progreso y Salud
- || Enrollment closed: IMproved PREdiction of Severe Sepsis in the Emergency Department (clinicaltrials.gov) - Oct 24, 2013
P=N/A, N=1000, Active, not recruiting, Sponsor: Axis Shield Diagnostics Ltd
Recruiting --> Completed Recruiting --> Active, not recruiting
- Enrollment open: The AVERT Sepsis Investigation (clinicaltrials.gov) - Oct 20, 2013
P=N/A, N=100, Recruiting, Sponsor: Christiana Care Health Services
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Enrollment change: VTICU: Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients (clinicaltrials.gov) - Oct 20, 2013
P=N/A, N=20, Completed, Sponsor: Charite University, Berlin, Germany
Not yet recruiting --> Recruiting N=30 --> 20
- Trial completion: VTICU: Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients (clinicaltrials.gov) - Oct 20, 2013
P=N/A, N=20, Completed, Sponsor: Charite University, Berlin, Germany
N=30 --> 20 Recruiting --> Completed
- rosuvastatin / Generic mfg.
Trial termination: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Completed Recruiting --> Terminated; stopped for futility
- rosuvastatin / Generic mfg.
Enrollment change: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Terminated; stopped for futility N=1000 --> 745
- Enrollment change: Prevalence of CVC-associated Sepsis and Use of Blood Cultures in Berlin - Brandenburg (clinicaltrials.gov) - Oct 16, 2013
P=N/A, N=80, Recruiting, Sponsor: Charite University, Berlin, Germany
N=1000 --> 745 N=250 --> 80
- | Trial initiation date: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Oct 15, 2013
P3, N=360, Recruiting, Sponsor: University of Sao Paulo
N=250 --> 80 Initiation date: Jan 2013 --> Oct 2013
- | Enrollment open: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Oct 15, 2013
P3, N=360, Recruiting, Sponsor: University of Sao Paulo
Initiation date: Jan 2013 --> Oct 2013 Not yet recruiting --> Recruiting