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51 Products |
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62 Mechanisms of Action |
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1119 News |
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- Trial completion date: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - May 21, 2014
P=N/A, N=361, Recruiting, Sponsor: University of British Columbia
Trial completion date: Dec 2013 --> Feb 2015
- Enrollment open: FC-Rev: Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in Septic Shock? (clinicaltrials.gov) - May 21, 2014
P=N/A, N=145, Recruiting, Sponsor: Centre Hospitalier Universitaire de Nīmes
Trial completion date: Dec 2013 --> Feb 2015 Not yet recruiting --> Recruiting
- Enrollment open: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - May 21, 2014
P=N/A, N=361, Recruiting, Sponsor: University of British Columbia
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial primary completion date: Infant Pulse Oximetry in Pakistan Study (clinicaltrials.gov) - May 20, 2014
P=N/A, N=3149, Completed, Sponsor: The Hospital for Sick Children
Not yet recruiting --> Recruiting Trial primary completion date: Aug 2012 --> Jun 2013
- Trial primary completion date, HEOR: SPOT(Light): Sepsis Pathophysiological & Organisational Timing (clinicaltrials.gov) - May 20, 2014
P=N/A, N=15602, Completed, Sponsor: Intensive Care National Audit & Research Centre
Trial primary completion date: Aug 2012 --> Jun 2013 Trial primary completion date: Feb 2012 --> Dec 2012
- Trial completion date: Infant Pulse Oximetry in Pakistan Study (clinicaltrials.gov) - May 20, 2014
P=N/A, N=3149, Completed, Sponsor: The Hospital for Sick Children
Trial primary completion date: Feb 2012 --> Dec 2012 Trial completion date: Oct 2012 --> Jun 2013
- Trial completion date, HEOR: SPOT(Light): Sepsis Pathophysiological & Organisational Timing (clinicaltrials.gov) - May 20, 2014
P=N/A, N=15602, Completed, Sponsor: Intensive Care National Audit & Research Centre
Trial completion date: Oct 2012 --> Jun 2013 Trial completion date: May 2012 --> Dec 2012
- Enrollment change: Infant Pulse Oximetry in Pakistan Study (clinicaltrials.gov) - May 20, 2014
P=N/A, N=3149, Completed, Sponsor: The Hospital for Sick Children
Trial completion date: May 2012 --> Dec 2012 N=1400 --> 3149
- Enrollment change, HEOR: SPOT(Light): Sepsis Pathophysiological & Organisational Timing (clinicaltrials.gov) - May 20, 2014
P=N/A, N=15602, Completed, Sponsor: Intensive Care National Audit & Research Centre
N=1400 --> 3149 N=9000 --> 15602
- Trial completion: Infant Pulse Oximetry in Pakistan Study (clinicaltrials.gov) - May 20, 2014
P=N/A, N=3149, Completed, Sponsor: The Hospital for Sick Children
N=9000 --> 15602 Active, not recruiting --> Completed
- Trial completion, HEOR: SPOT(Light): Sepsis Pathophysiological & Organisational Timing (clinicaltrials.gov) - May 20, 2014
P=N/A, N=15602, Completed, Sponsor: Intensive Care National Audit & Research Centre
Active, not recruiting --> Completed Recruiting --> Completed
- Leukine (sargramostim) / Partner Therap
Trial primary completion date: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) - May 19, 2014
P1/2, N=70, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Recruiting --> Completed Trial primary completion date: Sep 2013 --> Apr 2015
- Leukine (sargramostim) / Partner Therap
Trial completion date: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) - May 19, 2014
P1/2, N=70, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Trial primary completion date: Sep 2013 --> Apr 2015 Trial completion date: Oct 2013 --> Apr 2015
- Leukine (sargramostim) / Partner Therap
Enrollment change: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) - May 19, 2014
P1/2, N=70, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
Trial completion date: Oct 2013 --> Apr 2015 N=92 --> 70
- Leukine (sargramostim) / Partner Therap
Enrollment open: Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) - May 19, 2014
P1/2, N=70, Recruiting, Sponsor: Newcastle-upon-Tyne Hospitals NHS Trust
N=92 --> 70 Not yet recruiting --> Recruiting
- Trial primary completion date: Experimental Determination of Atot en Ka in the Critically Ill (clinicaltrials.gov) - May 18, 2014
P=N/A, N=30, Completed, Sponsor: VU University Medical Center
Not yet recruiting --> Recruiting Trial primary completion date: Dec 2013 --> May 2014
- heparin sodium injection / Generic mfg.
Trial withdrawal: Safety of Heparin in Patients With Septic Shock (clinicaltrials.gov) - May 18, 2014
P2, N=0, Withdrawn, Sponsor: University of Colorado, Denver
Trial primary completion date: Dec 2013 --> May 2014 Recruiting --> Withdrawn
- heparin sodium injection / Generic mfg.
Enrollment change: Safety of Heparin in Patients With Septic Shock (clinicaltrials.gov) - May 18, 2014
P2, N=0, Withdrawn, Sponsor: University of Colorado, Denver
Recruiting --> Withdrawn N=100 --> 0
- Trial completion: Experimental Determination of Atot en Ka in the Critically Ill (clinicaltrials.gov) - May 18, 2014
P=N/A, N=30, Completed, Sponsor: VU University Medical Center
N=100 --> 0 Not yet recruiting --> Completed
- | New P4 trial: Bacteraemia Secondary to Tooth Extraction: Chlorhexidine Prophylaxis Protocols (clinicaltrials.gov) - May 15, 2014
P4, N=208, Completed, Sponsor: University of Santiago de Compostela
- || Trial primary completion date: Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study) (clinicaltrials.gov) - May 11, 2014
P=N/A, N=1500, Completed, Sponsor: T2 Biosystems
Not yet recruiting --> Completed Trial primary completion date: Feb 2014 --> Apr 2014
- ||| Trial completion: Detecting Infections Rapidly and Easily for Candidemia Trial - Part 2 (direcT2 Study) (clinicaltrials.gov) - May 11, 2014
P=N/A, N=1500, Completed, Sponsor: T2 Biosystems
Trial primary completion date: Feb 2014 --> Apr 2014 Recruiting --> Completed
- Trial termination: ALB-CIRINF: Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis (clinicaltrials.gov) - May 11, 2014
P3, N=193, Terminated, Sponsor: Centre Hospitalier Universitaire de Besancon
Recruiting --> Completed Recruiting --> Terminated; decision of independent monitoring committee:Risk of death at 3 months higher in Albumin group than in control group, without reaching significance level.
- Trial completion date: ALB-CIRINF: Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis (clinicaltrials.gov) - May 11, 2014
P3, N=193, Terminated, Sponsor: Centre Hospitalier Universitaire de Besancon
Recruiting --> Terminated; decision of independent monitoring committee:Risk of death at 3 months higher in Albumin group than in control group, without reaching significance level. Trial completion date: Sep 2011 --> Jun 2012
- || New P3 trial: Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis (clinicaltrials.gov) - May 8, 2014
P3, N=100, Recruiting, Sponsor: Indonesia University
- Trial primary completion date: Urinary Heparanase Activity as a Predictor of Acute Kidney Injury in Critically Ill Adults (clinicaltrials.gov) - May 7, 2014
P=N/A, N=136, Recruiting, Sponsor: Denver Health and Hospital Authority
Trial completion date: Sep 2011 --> Jun 2012 Trial primary completion date: Jun 2014 --> Nov 2014
- Trial primary completion date: The Effect of Ketanserin on the Microcirculation in Sepsis (clinicaltrials.gov) - May 7, 2014
P3, N=10, Completed, Sponsor: Medical Centre Leeuwarden
Trial primary completion date: Jun 2014 --> Nov 2014 Trial primary completion date: Mar 2014 --> May 2014
- Trial completion date: The Effect of Ketanserin on the Microcirculation in Sepsis (clinicaltrials.gov) - May 7, 2014
P3, N=10, Completed, Sponsor: Medical Centre Leeuwarden
Trial primary completion date: Mar 2014 --> May 2014 Trial completion date: Jul 2014 --> May 2014
- Trial completion: The Effect of Ketanserin on the Microcirculation in Sepsis (clinicaltrials.gov) - May 7, 2014
P3, N=10, Completed, Sponsor: Medical Centre Leeuwarden
Trial completion date: Jul 2014 --> May 2014 Recruiting --> Completed
- Enrollment open: VENUS: Septic Gene Expression Using SeptiCyte (clinicaltrials.gov) - Apr 30, 2014
P=N/A, N=180, Recruiting, Sponsor: Intermountain Health Care, Inc.
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial completion: Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial? (clinicaltrials.gov) - Apr 25, 2014
P=N/A, N=103, Completed, Sponsor: Hopital Saint Roch
Not yet recruiting --> Recruiting Recruiting --> Completed
- || Trial initiation date: Assessing Childbirth-related Complications at the Community Level in Kenya (clinicaltrials.gov) - Apr 24, 2014
P=N/A, N=585, Completed, Sponsor: Wilson Liambila
Recruiting --> Completed Initiation date: Oct 2012 --> Aug 2012
- ||| Trial completion: Assessing Childbirth-related Complications at the Community Level in Kenya (clinicaltrials.gov) - Apr 24, 2014
P=N/A, N=585, Completed, Sponsor: Wilson Liambila
Initiation date: Oct 2012 --> Aug 2012 Not yet recruiting --> Completed
- Trial completion, Immune cell: Mitochondrial Function of Immune Cells in Sepsis (clinicaltrials.gov) - Apr 23, 2014
P=N/A, N=60, Completed, Sponsor: University Hospital Inselspital, Berne
Not yet recruiting --> Completed Not yet recruiting --> Completed
- Clinical: Antimicrobial Stewardship Reduces MDRO Isolates in Critically Ill Patients (clinicaltrials.gov) - Apr 21, 2014
P=N/A, N=978, Completed, Sponsor: Jianfeng Xie
- Clinical: Serum CD14 and CD88 Mointoring in ICU (clinicaltrials.gov) - Apr 20, 2014
P=N/A, N=80, Recruiting, Sponsor: Tanta University
- Clinical: Serum STREM and MNDA Mointoring in ICU (clinicaltrials.gov) - Apr 20, 2014
P=N/A, N=120, Recruiting, Sponsor: Tanta University
- | Trial initiation date: Effect of L-arginine and Glutamine on Preterm (clinicaltrials.gov) - Apr 13, 2014
P2/3, N=75, Completed, Sponsor: Ain Shams University
Not yet recruiting --> Completed Initiation date: Dec 2010 --> May 2011
- || hydrocortisone / Generic mfg.
New P3 trial: Effects of Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock (clinicaltrials.gov) - Apr 13, 2014
P3, N=240, Completed, Sponsor: Nanjing PLA General Hospital
- | Trial completion: Effect of L-arginine and Glutamine on Preterm (clinicaltrials.gov) - Apr 13, 2014
P2/3, N=75, Completed, Sponsor: Ain Shams University
Initiation date: Dec 2010 --> May 2011 Not yet recruiting --> Completed
- | midazolam hydrochloride / Generic mfg., dexmedetomidine / Generic mfg.
Clinical: The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis (clinicaltrials.gov) - Apr 8, 2014
P4, N=60, Not yet recruiting, Sponsor: National Taiwan University Hospital
- || Enrollment closed: Rapid Identification and Susceptibility Testing of Pathogens From Blood Cultures (clinicaltrials.gov) - Apr 7, 2014
P=N/A, N=600, Active, not recruiting, Sponsor: Mayo Clinic
Not yet recruiting --> Completed Recruiting --> Active, not recruiting
- Trial completion, IO biomarker: The Value of Memory B Cells Marker (CD27) and Howell Jelly Bodies Detrection in Critically Ill Patients (clinicaltrials.gov) - Apr 7, 2014
P=N/A, N=96, Completed, Sponsor: Tanta University
Recruiting --> Active, not recruiting Not yet recruiting --> Completed
- Trial completion: IL8 Monitoring and Its Correlation With 251-gene Polymorphism (clinicaltrials.gov) - Apr 5, 2014
P=N/A, N=80, Completed, Sponsor: Tanta University
Not yet recruiting --> Completed Recruiting --> Completed
- | ceftriaxone / Generic mfg., moxifloxacin intravenous / Generic mfg.
New P2 trial: Comparisons of Intravenous Ceftriaxone With Intravenous Moxifloxacin in ERCP (clinicaltrials.gov) - Mar 26, 2014
P2, N=160, Not yet recruiting, Sponsor: Kangbuk Samsung Hospital
- Enrollment change: MEDUSA: Medical Education for Sepsis Source Control and Antibiotics (clinicaltrials.gov) - Mar 20, 2014
P=N/A, N=4138, Completed, Sponsor: Center for Sepsis Control and Care, Germany
Recruiting --> Completed N=2000 --> 4138
- Trial completion: MEDUSA: Medical Education for Sepsis Source Control and Antibiotics (clinicaltrials.gov) - Mar 20, 2014
P=N/A, N=4138, Completed, Sponsor: Center for Sepsis Control and Care, Germany
N=2000 --> 4138 Active, not recruiting --> Completed
- Trial completion: Efficacy of Mw Vaccine in Treatment of Severe Sepsis (clinicaltrials.gov) - Mar 18, 2014
P2/3, N=50, Completed, Sponsor: Postgraduate Institute of Medical Education and Research
Active, not recruiting --> Completed Recruiting --> Completed
- | chloroquine phosphate / Generic mfg., azithromycin / Generic mfg.
Trial termination: Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa (clinicaltrials.gov) - Mar 17, 2014
P3, N=168, Terminated, Sponsor: Pfizer
Recruiting --> Completed Active, not recruiting --> Terminated; See termination reason in detailed description.
- Clinical: Candidemia in a Pediatric Center and Importance of Central Venous Catheter Removal (clinicaltrials.gov) - Mar 13, 2014
P=N/A, N=248, Completed, Sponsor: Hacettepe University