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55 Companies |
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51 Products |
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51 Products |
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62 Mechanisms of Action |
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0 Trials |
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1119 News |
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- | Phase classification: Probiotics for Prevention Neonatal Infection (clinicaltrials.gov) - Aug 23, 2023
P=N/A, N=4556, Terminated, Sponsor: University of Nebraska
Phase classification: P2/3 --> P=N/A
- | Trial completion: Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room (clinicaltrials.gov) - Apr 25, 2019
P=N/A, N=260, Completed, Sponsor: University of Texas Southwestern Medical Center
Phase classification: P2/3 --> P=N/A Recruiting --> Completed
- | Enrollment change, Trial withdrawal: Lactic Acid Levels In Hypotensive Patients Without(Standard) and With Tourniquet (clinicaltrials.gov) - Apr 21, 2019
P=N/A, N=0, Withdrawn, Sponsor: State University of New York - Upstate Medical University
Recruiting --> Completed N=100 --> 0 | Suspended --> Withdrawn
- | Trial completion, Gram negative: Duration of Antibiotics for the Treatment of Gram-negative Bacilli Bacteremia (clinicaltrials.gov) - Apr 20, 2019
P=N/A, N=604, Completed, Sponsor: Rabin Medical Center
N=100 --> 0 | Suspended --> Withdrawn Recruiting --> Completed
- | Trial completion: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - Apr 20, 2019
P=N/A, N=330, Completed, Sponsor: University of British Columbia
Recruiting --> Completed Active, not recruiting --> Completed
- | dexmedetomidine / Generic mfg.
Enrollment change, Trial completion date, Trial termination: The Effect of Dexmedetomidine on Microcirculation in Severe Sepsis (clinicaltrials.gov) - Mar 4, 2019
P4, N=12, Terminated, Sponsor: National Taiwan University Hospital
Active, not recruiting --> Completed N=60 --> 12 | Trial completion date: Dec 2018 --> Feb 2018 | Recruiting --> Terminated
- | Trial completion, Trial completion date, Trial primary completion date: Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients (clinicaltrials.gov) - Mar 1, 2019
P=N/A, N=273, Completed, Sponsor: Kuopio University Hospital
N=60 --> 12 | Trial completion date: Dec 2018 --> Feb 2018 | Recruiting --> Terminated Recruiting --> Completed | Trial completion date: Dec 2016 --> Jan 2019 | Trial primary completion date: Dec 2016 --> Jan 2019
- ||| Trial completion, Enrollment change: Evaluation of Essential Surgical Skills-Emergency Maternal and Child Health Training (clinicaltrials.gov) - Feb 5, 2019
P=N/A, N=36, Completed, Sponsor: Child Advocacy International
Recruiting --> Completed | Trial completion date: Dec 2016 --> Jan 2019 | Trial primary completion date: Dec 2016 --> Jan 2019 Recruiting --> Completed | N=24 --> 36
- | Phase classification: PreColos: Feeding Bovine Colostrum to Preterm Infants (clinicaltrials.gov) - Jan 22, 2019
P=N/A, N=52, Completed, Sponsor: Per Torp Sangild
Recruiting --> Completed | N=24 --> 36 Phase classification: P1/2 --> P=N/A
- | Phase classification: Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients (clinicaltrials.gov) - Jan 4, 2019
P=N/A, N=32, Completed, Sponsor: Isomark, LLC
Phase classification: P1/2 --> P=N/A Phase classification: P2 --> P=N/A
- | dexmedetomidine / Generic mfg.
Enrollment change, Trial completion date, Trial primary completion date: Dexmedetomidine on Microcirculation in Septic Shock (clinicaltrials.gov) - Dec 12, 2018
P4, N=44, Completed, Sponsor: Southeast University, China
Phase classification: P2 --> P=N/A N=30 --> 44 | Trial completion date: May 2016 --> May 2017 | Trial primary completion date: Apr 2016 --> Dec 2016
- | Enrollment change, Trial completion date, Trial termination, Trial primary completion date: Lung and Systemic Inflammation in the Critically Ill Patient (clinicaltrials.gov) - Dec 12, 2018
P=N/A, N=8, Terminated, Sponsor: Rigshospitalet, Denmark
N=30 --> 44 | Trial completion date: May 2016 --> May 2017 | Trial primary completion date: Apr 2016 --> Dec 2016 N=18 --> 8 | Trial completion date: Nov 2017 --> Dec 2018 | Recruiting --> Terminated | Trial primary completion date: Nov 2016 --> Dec 2018; Slow enrollment and therefore not possible to reach the estimated enrollment
- | leflunomide / Generic mfg.
Enrollment change, Trial completion date, Trial termination, Trial primary completion date: An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria (clinicaltrials.gov) - Dec 5, 2018
P2, N=24, Terminated, Sponsor: Changzheng-Cinkate
N=18 --> 8 | Trial completion date: Nov 2017 --> Dec 2018 | Recruiting --> Terminated | Trial primary completion date: Nov 2016 --> Dec 2018; Slow enrollment and therefore not possible to reach the estimated enrollment N=60 --> 24 | Trial completion date: Mar 2019 --> Jun 2018 | Recruiting --> Terminated | Trial primary completion date: Dec 2018 --> Jun 2018; Lack of recruitment
- | Enrollment closed: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - Nov 20, 2018
P=N/A, N=330, Active, not recruiting, Sponsor: University of British Columbia
N=60 --> 24 | Trial completion date: Mar 2019 --> Jun 2018 | Recruiting --> Terminated | Trial primary completion date: Dec 2018 --> Jun 2018; Lack of recruitment Recruiting --> Active, not recruiting
- | vancomycin / Generic mfg.
Trial completion, Enrollment change, Trial completion date, Trial primary completion date: RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates (clinicaltrials.gov) - Nov 2, 2018
P=N/A, N=111, Completed, Sponsor: Murdoch Childrens Research Institute
Recruiting --> Active, not recruiting Recruiting --> Completed | N=200 --> 111 | Trial completion date: Dec 2018 --> May 2018 | Trial primary completion date: Dec 2018 --> Apr 2018
- | Trial completion: PRODA: Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients (clinicaltrials.gov) - Nov 2, 2018
P=N/A, N=62, Completed, Sponsor: Seoul National University Hospital
Recruiting --> Completed | N=200 --> 111 | Trial completion date: Dec 2018 --> May 2018 | Trial primary completion date: Dec 2018 --> Apr 2018 Recruiting --> Completed
- | Trial completion, Enrollment change, Surgery: HAI: Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (clinicaltrials.gov) - Oct 23, 2018
P=N/A, N=911754, Completed, Sponsor: Dr. Donald Likosky
Recruiting --> Completed Active, not recruiting --> Completed | N=13925 --> 911754
- | Trial completion, Enrollment change, Surgery: Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2 (clinicaltrials.gov) - Oct 22, 2018
P=N/A, N=79, Completed, Sponsor: University of Michigan
Active, not recruiting --> Completed | N=13925 --> 911754 Active, not recruiting --> Completed | N=330 --> 79
- | Trial primary completion date: Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock (clinicaltrials.gov) - Oct 16, 2018
P=N/A, N=328, Recruiting, Sponsor: University of British Columbia
Active, not recruiting --> Completed | N=330 --> 79 Trial primary completion date: Jun 2018 --> Dec 2018
- | Enrollment change, Trial completion date, Trial primary completion date: Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients (clinicaltrials.gov) - Sep 6, 2018
P=N/A, N=362, Completed, Sponsor: Shanghai 10th People's Hospital
Trial primary completion date: Jun 2018 --> Dec 2018 N=1200 --> 362 | Trial completion date: Dec 2014 --> Dec 2015 | Trial primary completion date: Dec 2014 --> Dec 2015
- | cefazolin / Generic mfg.
Trial completion: An Open Label Study to Describe the Pharmacokinetics of Cefazolin in Preterm Neonates (clinicaltrials.gov) - Sep 4, 2018
P1, N=9, Completed, Sponsor: Phillip Brian Smith
N=1200 --> 362 | Trial completion date: Dec 2014 --> Dec 2015 | Trial primary completion date: Dec 2014 --> Dec 2015 Active, not recruiting --> Completed
- | Trial completion, Phase classification: HEMOSEPSIS: Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock (clinicaltrials.gov) - Aug 22, 2018
P4, N=153, Completed, Sponsor: University Hospital, Limoges
Active, not recruiting --> Completed Recruiting --> Completed | Phase classification: P3 --> P4
- | Trial completion, Enrollment change, Trial completion date, Trial primary completion date: Serial Therapeutic and Antifungal Monitoring Protocol (clinicaltrials.gov) - Aug 20, 2018
P=N/A, N=31, Completed, Sponsor: T2 Biosystems
Recruiting --> Completed | Phase classification: P3 --> P4 Recruiting --> Completed | N=60 --> 31 | Trial completion date: Jun 2016 --> Apr 2017 | Trial primary completion date: Jun 2016 --> Apr 2017
- | Trial completion, Trial completion date, Trial primary completion date: VENUS: Septic Gene Expression Using SeptiCyte (clinicaltrials.gov) - Aug 20, 2018
P=N/A, N=379, Completed, Sponsor: Immunexpress
Recruiting --> Completed | N=60 --> 31 | Trial completion date: Jun 2016 --> Apr 2017 | Trial primary completion date: Jun 2016 --> Apr 2017 Active, not recruiting --> Completed | Trial completion date: Aug 2018 --> Dec 2016 | Trial primary completion date: May 2018 --> Aug 2016
- | Trial completion, Enrollment change, Trial primary completion date: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Aug 20, 2018
P=N/A, N=5215, Completed, Sponsor: Mayo Clinic
Active, not recruiting --> Completed | Trial completion date: Aug 2018 --> Dec 2016 | Trial primary completion date: May 2018 --> Aug 2016 Recruiting --> Completed | N=15000 --> 5215 | Trial primary completion date: Mar 2018 --> Dec 2017
- | Trial completion, Enrollment change, Trial completion date, Trial primary completion date: DRIPICCO: Optimal Fluid Management in Adult Severe Malaria (clinicaltrials.gov) - Aug 16, 2018
P=N/A, N=156, Completed, Sponsor: University of Oxford
Recruiting --> Completed | N=15000 --> 5215 | Trial primary completion date: Mar 2018 --> Dec 2017 Recruiting --> Completed | N=120 --> 156 | Trial completion date: Dec 2015 --> Dec 2017 | Trial primary completion date: Dec 2015 --> Dec 2017
- | Trial completion, Trial completion date, Trial primary completion date: SIFT: Speed of Increasing Milk Feeds Trial (clinicaltrials.gov) - Jul 10, 2018
P=N/A, N=2804, Completed, Sponsor: University of Oxford
Recruiting --> Completed | N=120 --> 156 | Trial completion date: Dec 2015 --> Dec 2017 | Trial primary completion date: Dec 2015 --> Dec 2017 Active, not recruiting --> Completed | Trial completion date: Jan 2019 --> May 2018 | Trial primary completion date: Jan 2019 --> May 2018
- | piperacillin sodium/tazobactam sodium / Generic mfg.
Trial completion, Trial completion date, Trial primary completion date: Piperacillin/Tazobactam for Bacteremia With Organisms Producing Chromosomally-Encoded AmpC Beta-Lactamase (clinicaltrials.gov) - Jun 14, 2018
P=N/A, N=1000, Completed, Sponsor: University of Pittsburgh
Active, not recruiting --> Completed | Trial completion date: Jan 2019 --> May 2018 | Trial primary completion date: Jan 2019 --> May 2018 Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017
- | Neo-Synephrine (phenylephrine hydrochloride ophthalmic solution) / Paragon BioTeck, Bausch Health, Akorn
Enrollment change, Trial termination: Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill Patients (clinicaltrials.gov) - Jun 13, 2018
P4, N=17, Terminated, Sponsor: Vanderbilt University Medical Center
Active, not recruiting --> Completed | Trial completion date: Dec 2025 --> Dec 2017 | Trial primary completion date: Dec 2025 --> Dec 2017 N=75 --> 17 | Recruiting --> Terminated; Slow enrollment; Lack of support and equipoise
- | Trial completion date: Effects of Endotoxin in Normal Human Volunteers (clinicaltrials.gov) - Jun 2, 2018
P1, N=198, Completed, Sponsor: National Institutes of Health Clinical Center (CC)
N=75 --> 17 | Recruiting --> Terminated; Slow enrollment; Lack of support and equipoise Trial completion date: Mar 2007 --> May 2018
- | Enrollment change: CREST: Critical Care Excellence in Sepsis and Trauma (clinicaltrials.gov) - Apr 30, 2018
P=N/A, N=26, Completed, Sponsor: Medical University of South Carolina
Trial completion date: Mar 2007 --> May 2018 N=2600 --> 26
- | Trial completion: NOMS: Impact of Sunflower Seed Oil Massage on Neonatal Mortality and Morbidity in Nepal (clinicaltrials.gov) - Apr 23, 2018
P3, N=29260, Completed, Sponsor: Johns Hopkins Bloomberg School of Public Health
N=2600 --> 26 Active, not recruiting --> Completed
- | Trial completion, Trial completion date: Lactated Ringer Versus Albumin in Early Sepsis Therapy (clinicaltrials.gov) - Apr 6, 2018
P3, N=360, Completed, Sponsor: University of Sao Paulo
Active, not recruiting --> Completed Recruiting --> Completed | Trial completion date: Dec 2016 --> Dec 2017
- | Trial completion, Phase classification: Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study (clinicaltrials.gov) - Mar 27, 2018
P, N=20, Completed, Sponsor: Zsolt Molnár, MD, PhD, DEAA
Recruiting --> Completed | Trial completion date: Dec 2016 --> Dec 2017 Recruiting --> Completed | Phase classification: PN/A --> P
- | Trial completion date, Trial termination, Trial primary completion date: The Effect of Erythropietin on Microcircualtory Alteration in Intensive Care Unit Patients With Severe Sepsis (clinicaltrials.gov) - Mar 14, 2018
P=N/A, N=22, Terminated, Sponsor: London Health Sciences Centre
Recruiting --> Completed | Phase classification: PN/A --> P Trial completion date: Sep 2017 --> Mar 2018 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2018; Lack of recruitment
- || Trial completion date, Trial primary completion date: VENUS: Septic Gene Expression Using SeptiCyte (clinicaltrials.gov) - Feb 28, 2018
P=N/A, N=370, Active, not recruiting, Sponsor: Immunexpress
Trial completion date: Sep 2017 --> Mar 2018 | Recruiting --> Terminated | Trial primary completion date: Sep 2017 --> Mar 2018; Lack of recruitment Trial primary completion date: Apr 2017 --> May 2018 | Trial completion date: Jun 2017 --> Aug 2018
- | Trial completion, Enrollment change, Trial completion date: Changes in Exhaled 13CO2/12CO2 Breath Delta Value as an Early Indicator of Infection in ICU Patients (clinicaltrials.gov) - Feb 28, 2018
P2, N=32, Completed, Sponsor: Isomark, LLC
Trial primary completion date: Apr 2017 --> May 2018 | Trial completion date: Jun 2017 --> Aug 2018 Recruiting --> Completed | N=110 --> 32 | Trial completion date: Mar 2018 --> Dec 2017
- ||||||| Trial completion, Trial completion date, Trial primary completion date: Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasis (clinicaltrials.gov) - Feb 26, 2018
P3, N=60, Completed, Sponsor: Pfizer
Recruiting --> Completed | N=110 --> 32 | Trial completion date: Mar 2018 --> Dec 2017 Recruiting --> Completed | Trial completion date: Feb 2018 --> Feb 2018 | Trial primary completion date: Feb 2018 --> Feb 2018
- | vancomycin / Generic mfg.
Trial completion date, Trial primary completion date: RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates (clinicaltrials.gov) - Feb 6, 2018
P=N/A, N=200, Recruiting, Sponsor: Murdoch Childrens Research Institute
Recruiting --> Completed | Trial completion date: Feb 2018 --> Feb 2018 | Trial primary completion date: Feb 2018 --> Feb 2018 Trial primary completion date: Dec 2017 --> Dec 2018 | Trial completion date: Dec 2017 --> Dec 2018
- || leflunomide / Generic mfg.
Trial primary completion date: An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria (clinicaltrials.gov) - Jan 29, 2018
P2, N=60, Recruiting, Sponsor: Changzheng-Cinkate
Trial primary completion date: Dec 2017 --> Dec 2018 | Trial completion date: Dec 2017 --> Dec 2018 Trial primary completion date: Dec 2017 --> Dec 2018
- | Cubicin (daptomycin) / Merck (MSD)
Trial completion, Monotherapy: Efficacy of Daptomycin Plus Fosfomycin Versus Daptomycin for Treatment of MRSA Bacteremia (clinicaltrials.gov) - Jan 17, 2018
P3, N=167, Completed, Sponsor: Miquel Pujol
Trial primary completion date: Dec 2017 --> Dec 2018 Recruiting --> Completed
- || Mycamine (micafungin) / Astellas
Trial primary completion date: Study of FK463 in the Treatment of Candidemia or Invasive Candidiasis (clinicaltrials.gov) - Jan 10, 2018
P2, N=75, Completed, Sponsor: Astellas Pharma Inc
Recruiting --> Completed Trial primary completion date: Dec 2002 --> Jan 2002
- | Trial primary completion date: The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) (clinicaltrials.gov) - Jan 9, 2018
P=N/A, N=15000, Recruiting, Sponsor: Mayo Clinic
Trial primary completion date: Dec 2002 --> Jan 2002 Trial primary completion date: Dec 2017 --> Mar 2018
- | Trial completion: Epidemiology, Acute Management, and Outcomes of Patients With Sepsis Presenting to a Referral Hospital in Western Kenya (clinicaltrials.gov) - Jan 5, 2018
P=N/A, N=198, Completed, Sponsor: Duke University
Trial primary completion date: Dec 2017 --> Mar 2018 Active, not recruiting --> Completed
- | Trial completion: CENSER: Early Use of Norepinephrine in Septic Shock Resuscitation (clinicaltrials.gov) - Dec 22, 2017
P=N/A, N=310, Completed, Sponsor: Mahidol University
Active, not recruiting --> Completed Recruiting --> Completed
- |||| Trial primary completion date: Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasis (clinicaltrials.gov) - Dec 20, 2017
P3, N=60, Recruiting, Sponsor: Pfizer
Recruiting --> Completed Trial primary completion date: Jun 2019 --> Apr 2018
- | Trial completion: Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT (clinicaltrials.gov) - Dec 18, 2017
P=N/A, N=115, Completed, Sponsor: Sunnybrook Health Sciences Centre
Trial primary completion date: Jun 2019 --> Apr 2018 Recruiting --> Completed
- | Enrollment change, Trial initiation date, Trial primary completion date: Effect of Different Strategies for Titrating a High MAP on Microcirculation (clinicaltrials.gov) - Dec 14, 2017
P4, N=24, Completed, Sponsor: Southeast University, China
Recruiting --> Completed N=20 --> 24 | Initiation date: Sep 2011 --> Mar 2014 | Trial primary completion date: Dec 2014 --> Sep 2016
- | Solu-Cortef (hydrocortisone sodium succinate injection) / Pfizer
Trial completion: ADRENAL: ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (clinicaltrials.gov) - Dec 12, 2017
P4, N=3800, Completed, Sponsor: The George Institute
N=20 --> 24 | Initiation date: Sep 2011 --> Mar 2014 | Trial primary completion date: Dec 2014 --> Sep 2016 Active, not recruiting --> Completed
- ||| Trial completion, Phase classification: EUPHRATES: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock (clinicaltrials.gov) - Dec 5, 2017
P=N/A, N=450, Completed, Sponsor: Spectral Diagnostics (US) Inc.
Active, not recruiting --> Completed Active, not recruiting --> Completed | Phase classification: P3 --> PN/A