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21 Companies |
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32 Products |
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32 Products |
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31 Mechanisms of Action |
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0 Trials |
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632 News |
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- | lacosamide / Generic mfg.
Trial completion, Monotherapy: Trial to Assess Long-term Lacosamide (LCM) Monotherapy Use and Safety of LCM Monotherapy and Adjunctive Therapy for Partial-onset Seizures (clinicaltrials.gov) - Dec 12, 2014
P3, N=322, Completed, Sponsor: UCB Pharma
Active, not recruiting --> Completed
- ||| Trial completion: The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS) (clinicaltrials.gov) - Dec 7, 2014
P=N/A, N=409, Completed, Sponsor: Stanford University
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial primary completion date: Cardiac Arrhythmias in Epilepsy: the CARELINK-study (clinicaltrials.gov) - Dec 5, 2014
P=N/A, N=50, Recruiting, Sponsor: Stichting Epilepsie Instellingen Nederland
Active, not recruiting --> Completed Trial primary completion date: Jun 2015 --> Jun 2016
- topiramate / Generic mfg.
Trial primary completion date, Surgery: Preventing Brain Injury in Infants With Congenital Heart Disease (clinicaltrials.gov) - Dec 5, 2014
P1, N=24, Recruiting, Sponsor: University of California, Davis
Trial primary completion date: Jun 2015 --> Jun 2016 Trial primary completion date: Dec 2012 --> Dec 2014
- phenytoin / Generic mfg., levetiracetam / Generic mfg., fosphenytoin / Generic mfg.
Clinical: Antiepileptic Drugs and Vascular Risk Markers (clinicaltrials.gov) - Nov 25, 2014
P=N/A, N=52, Terminated, Sponsor: Thomas Jefferson University
Trial primary completion date: Dec 2012 --> Dec 2014 N=40 --> 52
- Enrollment open: Comparison of the New Fitting Method Cochlear Nucleus Fitting Software (NFS) With the Established Fitting Method Cochlear Nucleus Custom SoundTM Suite (CSS) (clinicaltrials.gov) - Nov 19, 2014
P=N/A, N=48, Recruiting, Sponsor: Cochlear
N=40 --> 52 Not yet recruiting --> Recruiting
- | Enrollment open: HYBERNATUS: Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care (clinicaltrials.gov) - Nov 7, 2014
P3, N=270, Recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting --> Recruiting Suspended --> Recruiting
- || Enrollment change: Acid Suppressing Drug Seizure Epidemiology Study (clinicaltrials.gov) - Nov 5, 2014
P=N/A, N=8500, Active, not recruiting, Sponsor: AstraZeneca
Suspended --> Recruiting N=534 --> 8500
- || esomeprazole / Generic mfg.
Enrollment closed: Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists (clinicaltrials.gov) - Nov 5, 2014
P=N/A, N=11000, Active, not recruiting, Sponsor: AstraZeneca
N=534 --> 8500 Recruiting --> Active, not recruiting
- | Enrollment change, Trial primary completion date: Ketogenic Diet for Refractory Status Epilepticus (clinicaltrials.gov) - Oct 30, 2014
P2, N=20, Recruiting, Sponsor: Johns Hopkins University
Recruiting --> Active, not recruiting N=10 --> 20 | Trial primary completion date: Nov 2014 --> Nov 2016
- |||| Aptiom (eslicarbazepine) / Sumitomo Pharma, BIAL
Trial completion, Trial initiation date: Effects of Eslicarbazepine Acetate (Esl, Bia 2-093) on Cognitive Function in Children With Partial Onset Seizures (clinicaltrials.gov) - Oct 24, 2014
P2, N=123, Completed, Sponsor: Bial - Portela C S.A.
N=10 --> 20 | Trial primary completion date: Nov 2014 --> Nov 2016 Active, not recruiting --> Completed | Initiation date: Nov 2007 --> Aug 2010
- Enrollment change, Trial termination: Neurostimulation to the Vagus Nerve for the Reduction in Frequency of Seizures Associated With Epilepsy (clinicaltrials.gov) - Oct 23, 2014
P=N/A, N=13, Terminated, Sponsor: ElectroCore LLC
Active, not recruiting --> Completed | Initiation date: Nov 2007 --> Aug 2010 N=30 --> 13 | Active, not recruiting --> Terminated; Slow enrollment
- Fycompa (perampanel) / Eisai
Trial primary completion date: A Long-term Extension Study of E2007 in Patients With Refractory Partial Seizures Uncontrolled With Other Anti-Epileptic Drugs (AEDs) (clinicaltrials.gov) - Oct 22, 2014
P2, N=30, Active, not recruiting, Sponsor: Eisai Co., Ltd.
N=30 --> 13 | Active, not recruiting --> Terminated; Slow enrollment Trial primary completion date: Oct 2015 --> Sep 2016
- lacosamide / Generic mfg.
Enrollment status: Study to Investigate Lacosamide as Add-on Therapy in Subjects ?4 Years to <17 Years of Age With Partial Onset Seizures (clinicaltrials.gov) - Oct 21, 2014
P3, N=308, Recruiting, Sponsor: UCB Pharma
Trial primary completion date: Oct 2015 --> Sep 2016 Recruiting --> Recruiting
- Enrollment change: Pediatric Seizure Movement Bed Alarm (clinicaltrials.gov) - Oct 17, 2014
P=N/A, N=200, Enrolling by invitation, Sponsor: Le Bonheur Children's Hospital
Recruiting --> Recruiting N=100 --> 200
- ||| Trial completion: PuLsE 2-Observational Long-Term Effectiveness Follow-Up Study of PuLsE 1 (clinicaltrials.gov) - Oct 17, 2014
P=N/A, N=81, Completed, Sponsor: Cyberonics, Inc.
N=100 --> 200 Active, not recruiting --> Completed
- |||| Fycompa (perampanel) / Eisai, Catalyst Pharma
Trial completion, Enrollment change: 4-Year Open-Label Extension Phase of the Parallel-Group Study of E2007 in Patients With Refractory Partial Seizures (clinicaltrials.gov) - Oct 11, 2014
P2, N=138, Completed, Sponsor: Eisai Inc.
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=108 --> 138
- | New P4 trial, Surgery: Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy (clinicaltrials.gov) - Oct 10, 2014
P4, N=120, Not yet recruiting, Sponsor: University College, London
- Enrollment closed: Stress Management Intervention for Living With Epilepsy (SMILE) (clinicaltrials.gov) - Oct 4, 2014
P2, N=100, Active, not recruiting, Sponsor: Montefiore Medical Center
Active, not recruiting --> Completed | N=108 --> 138 Recruiting --> Active, not recruiting
- ||||| brivaracetam / Generic mfg.
Enrollment closed: Evaluation of Long-term Safety, and Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects With Epilepsy (clinicaltrials.gov) - Oct 2, 2014
P3, N=650, Active, not recruiting, Sponsor: UCB Pharma SA
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting
- New P4 trial: Pre-oxygenation and Measures of Gas Exchanges During Seizures in the Epilepsy Monitoring Unit (clinicaltrials.gov) - Sep 16, 2014
P4, N=5, Suspended, Sponsor: New York University School of Medicine
- Clinical: People Presenting With Neurocysticercosis in North America (clinicaltrials.gov) - Sep 9, 2014
P=N/A, N=200, Recruiting, Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
- New P4 trial: A Taste and Acceptance Study of FruitiVits in Children Aged 4-8 Years Following a Ketogenic Diet. (clinicaltrials.gov) - Sep 4, 2014
P4, N=12, Enrolling by invitation, Sponsor: Vitaflo International, Ltd
- |||| Fycompa (perampanel) / Eisai, Catalyst Pharma
Trial primary completion date: Evaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures (clinicaltrials.gov) - Sep 4, 2014
P3, N=1443, Active, not recruiting, Sponsor: Eisai Inc.
Recruiting --> Active, not recruiting Trial primary completion date: Jul 2014 --> Nov 2014
- Clinical: Comparison of the New Fitting Method Cochlear Nucleus Fitting Software (NFS) With the Established Fitting Method Cochlear Nucleus Custom SoundTM Suite (CSS) (clinicaltrials.gov) - Aug 29, 2014
P=N/A, N=48, Not yet recruiting, Sponsor: Cochlear
- Trial completion, Surgery: Revisiting Survey Investigating Why Patients Are Not Receiving Home Anti-convulsant Medication Prior to Surgery/or Procedure Involving General Anesthesia (clinicaltrials.gov) - Aug 27, 2014
P=N/A, N=300, Completed, Sponsor: Vidya Raman
Trial primary completion date: Jul 2014 --> Nov 2014 Enrolling by invitation --> Completed
- Trial primary completion date: HYBERNATUS: Evaluation of Therapeutic Hypothermia in Convulsive Status EPILEPTICUS in Adults in Intensive Care (clinicaltrials.gov) - Aug 26, 2014
P3, N=270, Suspended, Sponsor: Assistance Publique - Hôpitaux de Paris
Enrolling by invitation --> Completed Trial primary completion date: Apr 2014 --> Apr 2015
- ||||| Fycompa (perampanel) / Eisai
New P4 trial: To Evaluate the Effect of Perampanel on Objective and Subjective Sleep in Subjects With Insomnia and Partial Onset Seizures (clinicaltrials.gov) - Aug 21, 2014
P4, N=62, Not yet recruiting, Sponsor: Eisai Inc.
- ||||||| lacosamide / Generic mfg.
Trial completion: A Trial to Evaluate the Efficacy and Safety of Adjunctive Therapy With Lacosamide in Adults With Partial-Onset Seizures (clinicaltrials.gov) - Aug 21, 2014
P3, N=548, Completed, Sponsor: UCB Pharma SA
Trial primary completion date: Apr 2014 --> Apr 2015 Active, not recruiting --> Completed
- Trial primary completion date: Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With Glioma (clinicaltrials.gov) - Aug 12, 2014
P=N/A, N=20, Recruiting, Sponsor: University of Alabama at Birmingham
Active, not recruiting --> Completed Trial primary completion date: Jan 2014 --> Jan 2015
- |||| Aptiom (eslicarbazepine) / Sumitomo Dainippon, BIAL
Trial primary completion date, Monotherapy: Eslicarbazepine Acetate Monotherapy Long Term Study (clinicaltrials.gov) - Aug 11, 2014
P3, N=348, Active, not recruiting, Sponsor: Sunovion
Trial primary completion date: Jan 2014 --> Jan 2015 Trial primary completion date: Apr 2014 --> Aug 2015
- ||||||| Vanquix (diazepam auto-injector) / Pfizer
Trial completion: Efficacy and Safety of Diazepam in the Management of Refractory Epilepsy in Selected Patients Who Require Intermittent Medical Intervention for Acute Repetitive Seizures. (clinicaltrials.gov) - Aug 8, 2014
P3, N=234, Completed, Sponsor: Pfizer
Trial primary completion date: Apr 2014 --> Aug 2015 Active, not recruiting --> Completed
- | levetiracetam / Generic mfg., carbamazepine / Generic mfg.
New P4 trial, Monotherapy: The Effects on Cognitive Function of Levetiracetam (Keppra (clinicaltrials.gov) - Aug 5, 2014
P4, N=75, Completed, Sponsor: Yonsei University
- phenytoin / Generic mfg., brivaracetam / Generic mfg.
Trial primary completion date: Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures (clinicaltrials.gov) - Aug 1, 2014
P2, N=50, Recruiting, Sponsor: UCB BIOSCIENCES, Inc.
Active, not recruiting --> Completed Trial primary completion date: Feb 2017 --> Aug 2016
- Enrollment closed, Trial primary completion date: Neurostimulation to the Vagus Nerve for the Reduction in Frequency of Seizures Associated With Epilepsy (clinicaltrials.gov) - Aug 1, 2014
P=N/A, N=30, Active, not recruiting, Sponsor: ElectroCore LLC
Trial primary completion date: Feb 2017 --> Aug 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Jul 2014
- Enrollment closed: Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Chronic-Dose 4-Period Replicate Design (clinicaltrials.gov) - Aug 1, 2014
P4, N=36, Active, not recruiting, Sponsor: University of Cincinnati
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2013 --> Jul 2014 Recruiting --> Active, not recruiting
- || lacosamide / Generic mfg.
Trial primary completion date, Combination therapy: VICTOS: Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat (clinicaltrials.gov) - Jul 25, 2014
P=N/A, N=374, Recruiting, Sponsor: UCB Pharma GmbH
Recruiting --> Active, not recruiting Trial primary completion date: Jan 2015 --> May 2015
- lacosamide / Generic mfg.
Enrollment closed, Trial primary completion date, Monotherapy: Add on Lacosamide Versus High Dose Monotherapy (clinicaltrials.gov) - Jul 23, 2014
P3, N=20, Active, not recruiting, Sponsor: Brigham and Women's Hospital
Trial primary completion date: Jan 2015 --> May 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2013 --> Dec 2014
- || esomeprazole / Generic mfg.
Enrollment change, Trial primary completion date: Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists (clinicaltrials.gov) - Jul 18, 2014
P=N/A, N=11000, Recruiting, Sponsor: AstraZeneca
Recruiting --> Active, not recruiting | Trial primary completion date: Feb 2013 --> Dec 2014 N=1500 --> 11000 | Trial primary completion date: May 2015 --> Aug 2015
- |||| Aptiom (eslicarbazepine) / Sumitomo Pharma, BIAL
Trial completion, Enrollment change: Safety and Efficacy of Eslicarbazepine Acetate as Adjunctive Therapy for Partial Seizures in Elderly Patients (clinicaltrials.gov) - Jul 18, 2014
P4, N=72, Completed, Sponsor: Bial - Portela C S.A.
N=1500 --> 11000 | Trial primary completion date: May 2015 --> Aug 2015 Active, not recruiting --> Completed | N=100 --> 72
- | lacosamide / Generic mfg.
Trial completion, Trial primary completion date: A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures (clinicaltrials.gov) - Jul 18, 2014
P2, N=47, Completed, Sponsor: UCB, Inc.
Active, not recruiting --> Completed | N=100 --> 72 Recruiting --> Completed | Trial primary completion date: Mar 2015 --> Jul 2014
- ||||| Aptiom (eslicarbazepine) / Sumitomo Pharma, BIAL
Enrollment change: Eslicarbazepine Acetate (BIA 2 093) as Therapy for Refractory Partial Seizures in Children (clinicaltrials.gov) - Jul 17, 2014
P3, N=304, Active, not recruiting, Sponsor: Bial - Portela C S.A.
Recruiting --> Completed | Trial primary completion date: Mar 2015 --> Jul 2014 N=252 --> 304
- | lacosamide / Generic mfg.
New P3 trial: Open-label Study to Evaluate the Safety and Tolerability of iv Lacosamide in Japanese Adults With Partial-onset Seizures (clinicaltrials.gov) - Jul 17, 2014
P3, N=10, Recruiting, Sponsor: UCB Japan Co. Ltd.
- phenytoin / Generic mfg., brivaracetam / Generic mfg.
Trial primary completion date: Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures (clinicaltrials.gov) - Jul 15, 2014
P2, N=50, Recruiting, Sponsor: UCB BIOSCIENCES, Inc.
N=252 --> 304 Trial primary completion date: Jun 2015 --> Feb 2017
- |||| zonisamide / Generic mfg.
Trial completion, Head-to-Head: Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug (clinicaltrials.gov) - Jul 14, 2014
P4, N=200, Completed, Sponsor: Eisai Inc.
Trial primary completion date: Jun 2015 --> Feb 2017 Recruiting --> Completed
- levetiracetam / Generic mfg.
Trial primary completion date: A Dose-Escalation, Safety and Feasibility Study of Enteral LVT for Seizure Control in Pediatric CM (clinicaltrials.gov) - Jul 12, 2014
P2, N=0, Recruiting, Sponsor: University of Rochester
Recruiting --> Completed Trial primary completion date: Aug 2014 --> Jun 2015
- Trial primary completion date: Exercise Education for Adults With Seizure Disorders (clinicaltrials.gov) - Jul 4, 2014
P0, N=50, Recruiting, Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
Trial primary completion date: Aug 2014 --> Jun 2015 Trial primary completion date: Jun 2014 --> Jun 2016
- ||||| levetiracetam / Generic mfg.
Enrollment change: A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures) (clinicaltrials.gov) - Jul 1, 2014
P3, N=361, Completed, Sponsor: UCB Japan Co. Ltd.
Trial primary completion date: Jun 2014 --> Jun 2016 N=276 --> 361
- ||||||| levetiracetam / Generic mfg.
Trial completion, Enrollment change: A Double-blind, Placebo-controlled Study of Levetiracetam in Epilepsy Patients With Generalized Tonic-clonic Seizures (Except Partial Seizures Evolving to Secondarily Generalized Seizures) (clinicaltrials.gov) - Jul 1, 2014
P3, N=361, Completed, Sponsor: UCB Japan Co. Ltd.
N=276 --> 361 Active, not recruiting --> Completed | N=276 --> 361
- Biomarker, Enrollment closed: Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC (clinicaltrials.gov) - Jun 27, 2014
P=N/A, N=40, Active, not recruiting, Sponsor: University of Alabama at Birmingham
Active, not recruiting --> Completed | N=276 --> 361 Recruiting --> Active, not recruiting