Sclerosis MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	5	10	15	20	25	30	35	40	45	50



CD20 inhib




IFNα stim




CD20 inhib




IL-6 inhib




Purinergic receptor P1 agon




S1P receptor 1 agon




c-KIT inhib




TGF-β1 inhib




DNA replication inhib




IL-1β inhib




Na+ channel inhib




Progesterone receptor agon




mTOR inhib




Dopamine agon




Glutamate receptor antag




HMG-CoA reductase inhib




IL-6 inhib




Immunosuppressant




Serotonin 2A receptor antag




T-cell activation inhib




TGF-β1 inhib




TNFα inhib




VEGFR inhib




mTOR inhib




Acetylcholine inhib




BAFF inhib




CD20 inhib




Cannabinoid receptor agon




Endothelin A receptor antag




GABA A receptor agon




GCR agon




HIF-1 inhib




IL-10 stim




IL-12 inhib




K+ channel antag




PDGFR inhib




c-KIT inhib




AChE inhib




AMPA receptor antag




Anti-inflammatory agent




Apoptosis stim




CD86 inhib




Cytokine mod




GHR agon




GM-CSF agon




Histamine H3 receptor partial antag




IL-23 inhib




IMPDH inhib




Kainic acid receptor antag




MHC class II gene mod



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