Sclerosis MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	5	10	15	20	25	30	35	40	45	50



Mast cell inhib




Membrane glycoprotein inhib




Mitochondrial permeability transition inhib




Mitochondrial protein stim




NF E2 related factor 2 stim




NOD2 mod




NRF2 activator




Nerve growth factor inhib




Nogo-A protein inhib




Osteoclast inhib




P-glycoprotein inhib




PDE5 inhib




PI3K inhib




PPAR γ agon




Phospholipase A2 inhib




Prostacyclin agon




Proteasome inhib




Protein 30S ribosomal subunit inhib




Protein 50S ribosomal subunit inhib




Relaxin receptor mod




RyR2 receptor mod




S100A9 inhib




SARS-CoV-2 3CL pro inhib




STAT3 inhib




Sclerostin inhib




Sigma-1 receptor agon




TLR mod




Voltage-gated sodium channel inhib




cGMP agon




α2 adrenergic receptor agon




α4 integrin antag



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