Scleroderma, Localized MOAs - LARVOL Sigma

Scleroderma, Localized

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27 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	1										2										3										4										5										6										7										8										9										10



CD20 inhib




CD20 inhib




Endothelin A receptor antag




IFNα 2b stim




IL-1β inhib




IL-6 inhib




IMPDH inhib




Immunosuppressant




PDGFR inhib




c-KIT inhib




c-KIT inhib




Apoptosis stim




CD20 inhib




CD86 inhib




Cytokine mod




Endothelin B receptor antag




Fyn inhib




GCR agon




IFNβ inhib




IL-10 stim




IL-6 inhib




Nerve growth factor inhib




PDE5 inhib




Prostacyclin agon




T-cell activation inhib




TLR8 agon




TNFα inhib