Scleroderma, Diffuse
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 02468101214161820
            
                                                                                                      
            
CD20 inhib           
          
            
            
CD20 inhib           
          
            
            
IL-6 inhib           
          
            
            
Bcr-abl tyrosine kinase inhib           
          
            
            
Endothelin A receptor antag           
          
            
            
Immunosuppressant           
          
            
            
PDGFR inhib           
          
            
            
c-KIT inhib           
          
            
            
Apoptosis stim           
          
            
            
GnRH agon           
          
            
            
IFNα 2b stim           
          
            
            
IL-1β inhib           
          
            
            
IL-6 inhib           
          
            
            
IMPDH inhib           
          
            
            
T-cell activation inhib           
          
            
            
TGF-β1 inhib           
          
            
            
TGF-β1 inhib           
          
            
            
TNF inhib           
          
            
            
Acetylcholine inhib           
          
            
            
BAFF inhib           
          
            
            
Bone morphogenetic protein receptor type II mod           
          
            
            
CD20 inhib           
          
            
            
CD86 inhib           
          
            
            
Calcineurin inhib           
          
            
            
Cytokine mod           
          
            
            
Endothelin B receptor antag           
          
            
            
Fyn inhib           
          
            
            
GCR agon           
          
            
            
Glutamate receptor antag           
          
            
            
GnRH agon           
          
            
            
HMG-CoA reductase inhib           
          
            
            
IFNβ inhib           
          
            
            
IL-10 stim           
          
            
            
IL-13 antag           
          
            
            
LPA1 receptor antag           
          
            
            
Na+ channel mod           
          
            
            
Nerve growth factor inhib           
          
            
            
PDE5 inhib           
          
            
            
Prostacyclin agon           
          
            
            
Relaxin receptor mod           
          
            
            
S100A9 inhib           
          
            
            
Serotonin 1D receptor agon           
          
            
            
Substance P release inhib           
          
            
            
TLR8 agon           
          
            
            
cGMP agon           
          
            
            
mTOR inhib           
          
            
            
mTOR inhib