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86 Companies |
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134 Products |
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134 Products |
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85 Mechanisms of Action |
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5 Trials |
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1881 News |
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- | Rexulti (brexpiprazole) / Lundbeck, Otsuka
Enrollment open, Monotherapy: Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Schizophrenia With Impulsivity (clinicaltrials.gov) - Feb 27, 2015
P3, N=36, Recruiting, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Not yet recruiting --> Recruiting
- Enrollment open, Trial primary completion date: Targeted Vitamin D Treatment of Schizophrenia-Associated Hyperprolinemia (clinicaltrials.gov) - Feb 24, 2015
P2, N=80, Recruiting, Sponsor: New York University School of Medicine
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2017 --> Dec 2017
- Enrollment closed, Enrollment change: Implementation of Illness Management and Recovery in Mental Health Services (clinicaltrials.gov) - Feb 24, 2015
P=N/A, N=40, Active, not recruiting, Sponsor: University Hospital, Akershus
Not yet recruiting --> Recruiting | Trial primary completion date: Aug 2017 --> Dec 2017 Recruiting --> Active, not recruiting | N=130 --> 40
- roluperidone (MIN-101) / Mitsubishi Tanabe, Minerva Neurosciences
Trial completion: Pharmacokinetic Study of MIN-101 in Healthy Subjects (clinicaltrials.gov) - Feb 24, 2015
P1, N=32, Completed, Sponsor: Minerva Neurosciences
Recruiting --> Active, not recruiting | N=130 --> 40 Recruiting --> Completed
- JNJ-39393406 / J&J
Enrollment open: Novel Smoking Cessation Drug for Schizophrenia (clinicaltrials.gov) - Feb 20, 2015
P2, N=60, Recruiting, Sponsor: K.N. Roy Chengappa
Recruiting --> Completed Not yet recruiting --> Recruiting
- Enrollment open, Trial primary completion date: Effects of Systematic Patient Feedback on Therapy Outcome (clinicaltrials.gov) - Feb 20, 2015
P=N/A, N=120, Recruiting, Sponsor: Norwegian University of Science and Technology
Not yet recruiting --> Recruiting Active, not recruiting --> Recruiting | Trial primary completion date: Jun 2014 --> Jun 2016
- valacyclovir / Generic mfg.
Trial primary completion date: To Rescue Cognition With Valaciclovir (clinicaltrials.gov) - Feb 19, 2015
P2, N=24, Recruiting, Sponsor: University Medical Centre Groningen
Active, not recruiting --> Recruiting | Trial primary completion date: Jun 2014 --> Jun 2016 Trial primary completion date: Aug 2014 --> Aug 2015
- Trial primary completion date: Measuring Time Windows in Patients With Schizophrenia and Healthy Controls (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=228, Recruiting, Sponsor: University Hospital, Strasbourg, France
Trial primary completion date: Aug 2014 --> Aug 2015 Trial primary completion date: Dec 2014 --> Dec 2016
- lenrispodun (ITI-214) - Intra / Cellular Therapies
Trial termination: Safety and Tolerability of Multiple Doses of ITI-214 in Healthy Adults and in Adults With Stable Schizophrenia (clinicaltrials.gov) - Feb 19, 2015
P1, N=76, Terminated, Sponsor: Takeda
Trial primary completion date: Dec 2014 --> Dec 2016 Recruiting --> Terminated; Business Decision; No Safety or Efficacy Concerns
- | Lu AF11167 / Lundbeck
Trial completion, Enrollment change: Safety and Tolerability Study of Lu AF11167 After Repeated Dosing in Patients With Schizophrenia (clinicaltrials.gov) - Feb 19, 2015
P1, N=47, Completed, Sponsor: H. Lundbeck A/S
Recruiting --> Terminated; Business Decision; No Safety or Efficacy Concerns Recruiting --> Completed | N=72 --> 47
- Trial completion: rTMS-induced Cumulative Pattern of sBDNF in Chronic Schizophrenia (clinicaltrials.gov) - Feb 19, 2015
P=N/A, N=21, Completed, Sponsor: Jeonbuk Provincial Maeumsarang Hospital
Recruiting --> Completed | N=72 --> 47 Recruiting --> Completed
- | Enrollment change, Trial primary completion date: The Topical Niacin Skin Flush Test in First Episode Psychosis (clinicaltrials.gov) - Feb 12, 2015
P3, N=100, Recruiting, Sponsor: Capital District Health Authority, Canada
Recruiting --> Completed N=200 --> 100 | Trial primary completion date: Dec 2014 --> Jun 2015
- Trial completion, Enrollment change: MEMENTA: Mental Health Care Provision for Adults With Intellectual Disability and a Mental Disorder (clinicaltrials.gov) - Feb 11, 2015
P=N/A, N=371, Completed, Sponsor: Technische Universität Dresden
N=200 --> 100 | Trial primary completion date: Dec 2014 --> Jun 2015 Recruiting --> Completed | N=600 --> 371
- | Enrollment closed: Shared Decision Making for Patients With First-admission Schizophrenia (clinicaltrials.gov) - Feb 10, 2015
P2/3, N=52, Active, not recruiting, Sponsor: Yokohama City University
Recruiting --> Completed | N=600 --> 371 Recruiting --> Active, not recruiting
- Enrollment closed, Trial primary completion date: Oxytocin as Adjunctive Therapy for Schizophrenia (clinicaltrials.gov) - Feb 10, 2015
P2, N=80, Active, not recruiting, Sponsor: IRCCS Centro San Giovanni di Dio Fatebenefratelli
Recruiting --> Active, not recruiting Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Jun 2015
- minocycline / Generic mfg., clozapine / Generic mfg.
Enrollment open: Minocycline Augmentation to Clozapine (clinicaltrials.gov) - Feb 9, 2015
P4, N=35, Recruiting, Sponsor: Emory University
Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> Jun 2015 Not yet recruiting --> Recruiting
- | ulotaront (SEP-363856) / Sumitomo Pharma, Otsuka
Trial completion: Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia (clinicaltrials.gov) - Feb 9, 2015
P1, N=48, Completed, Sponsor: Sunovion
Not yet recruiting --> Recruiting Active, not recruiting --> Completed
- ||||||| Rexulti (brexpiprazole) / Lundbeck, Otsuka
Trial completion: Brexpiprazole in Patients With Acute Schizophrenia (clinicaltrials.gov) - Feb 6, 2015
P3, N=465, Completed, Sponsor: H. Lundbeck A/S
Active, not recruiting --> Completed Active, not recruiting --> Completed
- quetiapine / Generic mfg.
Enrollment open: The Influence of Vitamin D on Atypical Antipsychotic-induced Weight Gain (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=40, Recruiting, Sponsor: Creighton University
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- |||||| Perseris (risperidone sustained-release 1-month depot) / Indivior, Reckitt Benckiser, HLS Therap
Clinical: Long Term Study of RBP 7000 in the Treatment of Subjects With Schizophrenia (clinicaltrials.gov) - Feb 5, 2015
P3, N=500, Recruiting, Sponsor: Reckitt Benckiser Pharmaceuticals Inc.
Not yet recruiting --> Recruiting Active, not recruiting --> Recruiting
- ||||||| Perseris (risperidone sustained-release 1-month depot) / Indivior, Reckitt Benckiser, HLS Therap
Clinical: Randomized, Double-blind, Placebo Controlled, Multi-center and Tolerability of RBP-7000 in Schizophrenia Patients (clinicaltrials.gov) - Feb 5, 2015
P3, N=259, Completed, Sponsor: Reckitt Benckiser Pharmaceuticals Inc.
Active, not recruiting --> Recruiting Recruiting --> Completed | N=339 --> 259 | Trial primary completion date: Mar 2015 --> Dec 2014
- Trial primary completion date: Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=50, Recruiting, Sponsor: Centre for Addiction and Mental Health
Recruiting --> Completed | N=339 --> 259 | Trial primary completion date: Mar 2015 --> Dec 2014 Trial primary completion date: Dec 2014 --> Sep 2015
- Phase classification: Cerebellar rTMS for the Treatment of Schizophrenic Patients (clinicaltrials.gov) - Feb 5, 2015
P=N/A, N=20, Completed, Sponsor: Beth Israel Deaconess Medical Center
Trial primary completion date: Dec 2014 --> Sep 2015 Phase classification: P1 --> P=N/A
- Trial completion, Trial initiation date: Clinical Estradiol Trial in Women With Schizophrenia (clinicaltrials.gov) - Feb 5, 2015
P2, N=100, Completed, Sponsor: Bayside Health
Phase classification: P1 --> P=N/A Recruiting --> Completed | Initiation date: Jan 2002 --> Jan 2001
- Chantix (varenicline) / Pfizer
Trial primary completion date: Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=40, Recruiting, Sponsor: Centre for Addiction and Mental Health
Recruiting --> Completed | Initiation date: Jan 2002 --> Jan 2001 Trial primary completion date: Dec 2014 --> Aug 2016
- Trial initiation date: Transcranial Direct Current Stimulation Influences on Cognitive Inhibition in Schizophrenia (clinicaltrials.gov) - Feb 3, 2015
P=N/A, N=30, Not yet recruiting, Sponsor: Bar-Ilan University, Israel
Trial primary completion date: Dec 2014 --> Aug 2016 Initiation date: Jul 2014 --> Jan 2015
- ||| l-methylfolate / Generic mfg.
Trial completion: A Placebo-Controlled Study of Physiologic Effects of L-methylfolate in Schizophrenia Patients (clinicaltrials.gov) - Feb 2, 2015
P=N/A, N=55, Completed, Sponsor: Pamlab, Inc.
Initiation date: Jul 2014 --> Jan 2015 Active, not recruiting --> Completed
- || Arvisol (cannabidiol) / Echo Pharma
Preclinical, Trial primary completion date: CBD-IS: Cannabidiol as a Different Type of an Antipsychotic: Drug Delivery and Interaction Study (clinicaltrials.gov) - Feb 2, 2015
P1, N=74, Recruiting, Sponsor: Central Institute of Mental Health, Mannheim
Active, not recruiting --> Completed Trial primary completion date: Jun 2014 --> Jun 2015
- Enrollment closed, Trial primary completion date: Remediation of Working Memory in Schizophrenia (clinicaltrials.gov) - Jan 30, 2015
P=N/A, N=80, Active, not recruiting, Sponsor: Minneapolis Veterans Affairs Medical Center
Trial primary completion date: Jun 2014 --> Jun 2015 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Apr 2015
- raloxifene hydrochloride / Generic mfg.
Trial completion, Enrollment change, Trial primary completion date: SERM: Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia (clinicaltrials.gov) - Jan 30, 2015
P4, N=54, Completed, Sponsor: The Alfred
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2014 --> Apr 2015 Recruiting --> Completed | N=90 --> 54 | Trial primary completion date: Dec 2015 --> Dec 2014
- | aripiprazole / Generic mfg.
Enrollment change, Trial primary completion date: ATTAIN 267: Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features. (clinicaltrials.gov) - Jan 29, 2015
P3, N=511, Terminated, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting --> Completed | N=90 --> 54 | Trial primary completion date: Dec 2015 --> Dec 2014 N=651 --> 511 | Trial primary completion date: Dec 2014 --> Aug 2014
- ||| Clinical: A Shared Decision-making Training for Inpatients With Schizophrenia (clinicaltrials.gov) - Jan 29, 2015
P=N/A, N=240, Active, not recruiting, Sponsor: Technische Universität München
- ||||||| bitopertin (DISC-1459) / Disc Medicine
Trial completion: A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25305) (clinicaltrials.gov) - Jan 28, 2015
P3, N=604, Completed, Sponsor: Hoffmann-La Roche
N=651 --> 511 | Trial primary completion date: Dec 2014 --> Aug 2014 Active, not recruiting --> Completed
- naratriptan / Generic mfg.
Clinical: Efficacy of a Triptan in the Treatment of Hostility and Aggression Among Convicts With a Psychiatric Treatment Order (clinicaltrials.gov) - Jan 26, 2015
P4, N=8, Terminated, Sponsor: UMC Utrecht
Active, not recruiting --> Completed N=30 --> 8 | Recruiting --> Terminated; Required number of subjects to be included could not be accomplished
- ||| Trial completion, Enrollment change: Parallel Group, Multiple Dose Pharmacokinetics Study of Five Antipsychotic Medications in Psychiatric Participants (clinicaltrials.gov) - Jan 26, 2015
P1, N=305, Completed, Sponsor: Janssen Research & Development, LLC
N=30 --> 8 | Recruiting --> Terminated; Required number of subjects to be included could not be accomplished Active, not recruiting --> Completed | N=235 --> 305
- Trial completion: Acceptance and Efficacy of Live Supervision (clinicaltrials.gov) - Jan 22, 2015
P=N/A, N=42, Completed, Sponsor: Goethe University
Active, not recruiting --> Completed | N=235 --> 305 Active, not recruiting --> Completed
- Enrollment closed, Trial primary completion date: Social Cognitive Training for Psychosis: Treatment Development (clinicaltrials.gov) - Jan 22, 2015
P1, N=40, Active, not recruiting, Sponsor: Yale University
Active, not recruiting --> Completed Not yet recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> May 2015
- Biomarker: Cognitive Remediation Therapy in Schizophrenia: Effects on BDNF Levels (clinicaltrials.gov) - Jan 20, 2015
P=N/A, N=60, Recruiting, Sponsor: Hospital Clinic of Barcelona
- Clinical: Mindfulness Group-based Intervention for Early Psychosis: A Pilot Study (clinicaltrials.gov) - Jan 20, 2015
P=N/A, N=30, Not yet recruiting, Sponsor: Lawson Health Research Institute
- Enrollment open, Trial primary completion date: Resveratrol, Cardiovascular Risk Markers And Cognitive Performance In Patients With Schizophrenia (clinicaltrials.gov) - Jan 15, 2015
P2, N=20, Recruiting, Sponsor: Federal University of Rio Grande do Sul
Not yet recruiting --> Active, not recruiting | Trial primary completion date: Dec 2014 --> May 2015 Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2014 --> Jan 2015
- raloxifene hydrochloride / Generic mfg.
Trial primary completion date: SERM: Selective Estrogen Receptor Modulators - A Potential Treatment for Psychotic Symptoms of Schizophrenia (clinicaltrials.gov) - Jan 15, 2015
P4, N=90, Recruiting, Sponsor: The Alfred
Not yet recruiting --> Recruiting | Trial primary completion date: Mar 2014 --> Jan 2015 Trial primary completion date: Dec 2014 --> Dec 2015
- ||||| Rexulti (brexpiprazole) / Lundbeck, Otsuka
Enrollment closed: Brexpiprazole in Patients With Acute Schizophrenia (clinicaltrials.gov) - Jan 15, 2015
P3, N=465, Active, not recruiting, Sponsor: H. Lundbeck A/S
Trial primary completion date: Dec 2014 --> Dec 2015 Recruiting --> Active, not recruiting
- || Trial initiation date: An Non-Interventional Study of Patients With Persistent Symptoms of Schizophrenia (clinicaltrials.gov) - Jan 13, 2015
P=N/A, N=1500, Recruiting, Sponsor: Hoffmann-La Roche
Recruiting --> Active, not recruiting Initiation date: Feb 2011 --> Sep 2012
- Clinical: REACH: Researching the Effectiveness of Acceptance-Based Coping During Hospitalization (clinicaltrials.gov) - Jan 13, 2015
P=N/A, N=60, Not yet recruiting, Sponsor: Butler Hospital
- EVP6308 / Forum Pharmaceuticals
Trial completion: Study to Assess the Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Effects of EVP-6308 and the Potential of EVP-6308 to Affect the PK Properties of the Antipsychotic Regimen in Subjects With Schizophrenia Currently Receiving Stable Treatment With up to 2 Atypical Antipsychotics (clinicaltrials.gov) - Jan 12, 2015
P1, N=40, Completed, Sponsor: FORUM Pharmaceuticals Inc
Initiation date: Feb 2011 --> Sep 2012 Recruiting --> Completed
- ||| Abilify MyCite (aripiprazole tablets embedded with sensor) / Otsuka
Enrollment closed, Enrollment change, Trial primary completion date: Open-label Study to Assess Usability of the Medical Information Device #1 (MIND1) System in Adults With Schizophrenia On Oral Aripiprazole (clinicaltrials.gov) - Jan 9, 2015
P2, N=64, Active, not recruiting, Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.
Recruiting --> Completed Not yet recruiting --> Active, not recruiting | N=32 --> 64 | Trial primary completion date: Dec 2014 --> Jul 2015
- Clinical: Evaluation of the In SHAPE Fitness Intervention for Adults With Serious Mental Illness (clinicaltrials.gov) - Jan 8, 2015
P=N/A, N=133, Completed, Sponsor: Dartmouth-Hitchcock Medical Center
- | APN1125 / CoMentis, Alpharmagen
New P1 trial: Safety, Tolerability, and Pharmacokinetics of Single Doses of APN1125 in Healthy Normal Subjects (clinicaltrials.gov) - Jan 6, 2015
P1, N=50, Recruiting, Sponsor: CoMentis
- Trial completion: Peer Support for Severe Mental Disorders (clinicaltrials.gov) - Jan 5, 2015
P=N/A, N=200, Completed, Sponsor: Universitätsklinikum Hamburg-Eppendorf
Not yet recruiting --> Active, not recruiting | N=32 --> 64 | Trial primary completion date: Dec 2014 --> Jul 2015 Active, not recruiting --> Completed
- ||| Clinical: Padres Efectivos (Parent Activation): Skills Latina Mothers Use to Get Healthcare for Their Children (clinicaltrials.gov) - Jan 2, 2015
P=N/A, N=270, Recruiting, Sponsor: University of North Carolina, Chapel Hill