Sarcopenia News - LARVOL Sigma

Sarcopenia	Welcome, Profile Billing Logout

«1 2...31 32 33 34 353637 38 39 40 41...401 402 »

|||||||||| Journal: Younger Older Americans and Sarcopenic Obesity: The Moderating Role of Living Alone. (Pubmed Central) - Aug 8, 2024
First, the risk of sarcopenic obesity is higher among younger cohorts of older Americans relative to older cohorts (born before 1931). Second, living alone may not necessarily be considered a worse health condition, particularly for younger female cohorts.

|||||||||| Tyrisa (darapladib) / GSK
Journal: Predictive and therapeutic value of lipoprotein-associated phospholipaseA2 in sarcopenia in chronic obstructive pulmonary disease. (Pubmed Central) - Aug 8, 2024
Lp-PLA2 could be a potential indicator for sarcopenia in COPD. Darapladib, a Lp-PLA2 inhibitor, can alleviate CS-induced skeletal muscle dysfunction and represents a potential therapeutic for sarcopenia in COPD.

|||||||||| Retrospective data, Review, Journal: ASO Author Reflections: Prevalence and Association of Sarcopenia with Mortality in Patients with Head and Neck Cancer-A Systematic Review and Meta-analysis. (Pubmed Central) - Aug 8, 2024
Darapladib, a Lp-PLA2 inhibitor, can alleviate CS-induced skeletal muscle dysfunction and represents a potential therapeutic for sarcopenia in COPD. No abstract available

|||||||||| Retrospective data, Journal: A Nomogram Including Sarcopenia for Predicting Progression-Free Survival in Patients with Localized Papillary Renal Cell Carcinoma: A Retrospective Cohort Study. (Pubmed Central) - Aug 8, 2024
No abstract available A prognostic nomogram, including sarcopenia, SAT, PRAT, tumor diameter, and surgical technique, was constructed to calculate the probability of progression for localized pRCC patients and needs further external validation for clinical use in the future.

|||||||||| Biomarker, Journal: Alterations in Sarcopenia Index are Associated with Inflammation, Gut and Oral Microbiota among Heart Failure, Left Ventricular Assist Device and Heart Transplant Patients. (Pubmed Central) - Aug 7, 2024
SI levels decreased in symptomatic HF and remained decreased long-term after LVAD and HT. In the combined cohort, SI levels covaried with inflammation in a similar fashion and were

|||||||||| Journal: Enhancing the 4M framework: the critical role of malnutrition in immobility among hospitalized patients. (Pubmed Central) - Aug 7, 2024
In the combined cohort, SI levels covaried with inflammation in a similar fashion and were No abstract available

|||||||||| Retrospective data, Journal, Surgery: Sarcopenia measured by tomography as a predictor of morbidity and mortality in thoracic surgery. A retrospective cohort study. (Pubmed Central) - Aug 7, 2024
No abstract available Sarcopenia, defined as low muscle area in the pectoral and erector spinae muscles, is associated with increased morbidity and mortality in patients undergoing thoracic surgery.

|||||||||| Observational data, Journal: Association of high-density lipoprotein cholesterol with sarcopenia in Chinese community-dwelling middle-aged and older adults: Evidence from 4-year longitudinal study from the CHARLS. (Pubmed Central) - Aug 7, 2024
Sarcopenia, defined as low muscle area in the pectoral and erector spinae muscles, is associated with increased morbidity and mortality in patients undergoing thoracic surgery. High HDL-C levels were associated with higher risk of sarcopenia among middle-aged and older Chinese adults, and appropriate control of its high levels informs the management of sarcopenia.

|||||||||| Journal: Association between the thickness or area of the temporal muscle and skeletal muscle mass in bioimpedance analysis. (Pubmed Central) - Aug 7, 2024
High HDL-C levels were associated with higher risk of sarcopenia among middle-aged and older Chinese adults, and appropriate control of its high levels informs the management of sarcopenia. We observed moderate to strong positive correlations between body composition analysis measured by BIA and TMT or TMA, suggesting that TMT or TMA could serve as a reliable surrogate marker for identifying low skeletal muscle mass in cerebrovascular disease.

|||||||||| Review, Journal: Bridging the critically ill acute on chronic liver failure patient through liver transplantation. (Pubmed Central) - Aug 7, 2024
The development of sepsis and prolonged organ support may preclude LT or diminish its chances of success. The current review describes strategies to bridge severe ACLF patients to LT, highlights the minimal evaluation required for listing and the currently suggested contraindications to proceed with LT and addresses different aspects of management during the perioperative and early post-transplant period.

|||||||||| Retrospective data, Review, Journal: The association of alcohol consumption with the risk of sarcopenia: a dose-response meta-analysis. (Pubmed Central) - Aug 7, 2024
The results of this meta-analysis indicate that alcohol consumption is not a risk factor for the development of sarcopenia. Any suggestion of a putative protective effect of alcohol should be treated with caution, particularly in light of the overall lack of relationship reported in the present comprehensive meta-analysis.

|||||||||| Review, Journal: Sarcopenic Obesity and Cardiovascular Disease: An Overlooked but High-Risk Syndrome. (Pubmed Central) - Aug 7, 2024
Although current management revolves around diet for weight loss coupled with resistance training to mitigate further muscle loss, emerging pharmacologic therapies have shown promising results. As the global population ages, diagnosing and managing SO will become imperative to alleviate the cardiovascular burden.

|||||||||| Review, Journal: Urogeriatric thinking using the example of antiandrogen therapy for prostate cancer (Pubmed Central) - Aug 7, 2024
These considerations should be compared with the patient's individual risk profile in order to prevent side effects from negating the effect of the treatment, for example by worsening the patient's self-help status. With regard to androgen deprivation in prostate cancer-which often is used uncritically-it is important to consider possible side effects such as osteoporosis, sarcopenia, anemia, and cognitive impairment in terms of a

|||||||||| Observational data, Journal: The clinical utility of handgrip strength as a malnutrition screening tool in hospitalized older adults: a cross-sectional study in Saudi Arabia. (Pubmed Central) - Aug 7, 2024
Therefore, HGS may not be adequate as a standalone tool to assess nutritional status in hospitalized older adults. Replication of this study using locally reliable and validated HGS cut-off values is warranted to confirm these findings.

|||||||||| Journal: Standardization of body composition parameters between GE Lunar iDXA and Hologic Horizon A and their clinical impact. (Pubmed Central) - Aug 7, 2024
The provided standardization equations address these issues and improve the agreement between devices. Future studies and disease definitions should consider these differences.

|||||||||| Journal, Surgery: Does computed tomography-derived volumometry and densitometry of psoas muscle really correlate with complications in rectal cancer patients after elective surgery? (Pubmed Central) - Aug 7, 2024
Lower rectal resections are burdened with a higher risk of post-operative complications, especially AL. Monitoring of CRP levels remains an important marker in the prediction of AL due to its negative predictive value.

|||||||||| Journal: Detecting sarcopenia in obesity: emerging new approaches. (Pubmed Central) - Aug 7, 2024
Monitoring of CRP levels remains an important marker in the prediction of AL due to its negative predictive value. New consensus tools for sarcopenic obesity diagnosis are likely to improve awareness, understanding, identification and treatment of this under-recognized obesity phenotype.

|||||||||| Journal: Assessing cachexia in obesity: contradiction or perfectly possible? (Pubmed Central) - Aug 7, 2024
Weight loss can occur in anyone with cancer, however its priority for clinical management may be lesser in obese versus low body weight individuals. Sarcopenic obesity is strongly associated with a poor clinical outcome and deserves further research, diagnosis in clinical practice, and new strategies for mitigation.

|||||||||| Trial completion date, Trial primary completion date: Treatment of Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C (clinicaltrials.gov) - Aug 7, 2024
P3, N=96, Active, not recruiting, Sponsor: Dayanand Medical College and Hospital
Sarcopenic obesity is strongly associated with a poor clinical outcome and deserves further research, diagnosis in clinical practice, and new strategies for mitigation. Trial completion date: Oct 2023 --> Oct 2024 | Trial primary completion date: Aug 2023 --> Jan 2024

|||||||||| Trial completion, Trial completion date: Impact of Protein-Enriched Lacto-Vegetarian Soup on Muscle Mass and Muscle Strength Among Older Adults (clinicaltrials.gov) - Aug 7, 2024
P=N/A, N=100, Completed, Sponsor: Buddhist Tzu Chi General Hospital
Trial completion date: Oct 2023 --> Oct 2024 | Trial primary completion date: Aug 2023 --> Jan 2024 Recruiting --> Completed | Trial completion date: Dec 2023 --> Aug 2023

|||||||||| Journal: Cohort profile: the Taiwan Initiative for Geriatric Epidemiological Research - a prospective cohort study on cognition. (Pubmed Central) - Aug 6, 2024
TIGER has published novel and multidisciplinary research on cognitive-related outcomes in older adults, including environmental exposures (indoor and ambient air pollution), multimorbidity, sarcopenia, frailty, biomarkers (brain and retinal images, renal and inflammatory markers), and diet. TIGER's meticulous design, multidisciplinary data, and novel findings elucidate the complex etiology of cognitive impairment and frailty, offering valuable insights into factors that can be used to predict and prevent dementia in the preclinical phase.

|||||||||| Clinical, Retrospective data, Review, Journal: Gut microbial composition is altered in sarcopenia: A systematic review and meta-analysis of clinical studies. (Pubmed Central) - Aug 6, 2024
In conclusion, sarcopenia was found to be associated with reduced richness of GM, and supplementing intestinal bacteria described above may contribute to preventing and treating this muscle disease. The research protocol was registered and approved in PROSPERO (CRD42023412849).

|||||||||| Journal: A sarcopenia screening test predicts mortality among hospitalized cancer patients. (Pubmed Central) - Aug 6, 2024
Age was a predictor of 2-year all-cause mortality among patients aged ?65?years but not among those aged <65?years (OS: 25.6% vs. 100%, p?=?0.04). To summarize, the sarcopenia screening results were found to predict OS and all-cause mortality and may be helpful for patient stratification during in-hospital care.

|||||||||| Retrospective data, Journal: Automated Comprehensive CT Assessment of the Risk of Diabetes and Associated Cardiometabolic Conditions. (Pubmed Central) - Aug 6, 2024

|||||||||| Xifaxan (rifaximin) / Alfa Wassermann, Bausch Health
Review, Journal: Advances in the management of complications from cirrhosis. (Pubmed Central) - Aug 6, 2024
Additionally, non-selective beta blockers, especially carvedilol, can improve portal hypertension and may even have a survival benefit...While lactulose and rifaximin are the preferred treatments for hepatic encephalopathy, many alternative treatment options may be used in refractory cases and even procedural interventions such as shunt embolization may be of benefit...Lastly, the investigation of systemic therapies, in particular immunotherapy, has revolutionized the management of HCC. These topics will be discussed in detail in this review.

|||||||||| Journal, HEOR: Analysis of Risk Factors of Sarcopenia in Patients with Maintenance Hemodialysis and Its Correlation with Emotional Status and Quality of Life. (Pubmed Central) - Aug 6, 2024
Correlation analysis showed that sarcopenia was positively correlated with SAS and SDS scores and negatively correlated with SF-36 total score (p < 0.05). The risk of sarcopenia was higher among MHD patients who were older, male, single, with a longer MHD duration, lower economic status, lower BMI, comorbid diabetes and lower levels of creatinine.

|||||||||| Journal: Skeletal muscle architecture and aging: A comparison of ultrasound techniques and an assessment of intrarater reliability. (Pubmed Central) - Aug 6, 2024
The risk of sarcopenia was higher among MHD patients who were older, male, single, with a longer MHD duration, lower economic status, lower BMI, comorbid diabetes and lower levels of creatinine. Our findings suggest that participant posture during imaging impacts the absolute values and intrarater reliability of ultrasound-determined muscle characteristics in a muscle-specific fashion, and this effect is greater in older compared to younger individuals.

|||||||||| metformin / Generic mfg.
Journal: Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism. (Pubmed Central) - Aug 6, 2024
In this review, we summarize the upto- date studies on the effects of anti-diabetic drugs and some natural compounds on skeletal muscle metabolism, focusing primarily on emerging data from pre-clinical to clinical studies. Given the extensive use of anti-diabetic drugs and the common sarcopenia, a better understanding of energy metabolism in skeletal muscle deserves attention in future studies.

|||||||||| New trial: Sarcopenic Index and Related Factors in Patients With Type 2 Diabetes (clinicaltrials.gov) - Aug 6, 2024
P=N/A, N=839, Completed, Sponsor: Goztepe Prof Dr Suleyman Yalc?n City Hospital

|||||||||| Journal: Body composition is associated with postoperative complications in perihilar cholangiocarcinoma. (Pubmed Central) - Aug 5, 2024
BC is highly associated with severe postoperative complications in patients with pCCA and shows tendency to be associated impaired overall survival. Preoperative assessment of BC and interventions to improve BC might therefore be key to improve outcome in pCCA patients undergoing surgical therapy.

|||||||||| Review, Journal: The impact of sarcopenia on the efficacy of PD-1 inhibitors in non-small cell lung cancer and potential strategies to overcome resistance. (Pubmed Central) - Aug 5, 2024
Additionally, we present tailored intervention strategies for sarcopenic patients undergoing PD-1 inhibitor therapy, aiming to optimize treatment efficacy and enhance patient quality of life. Nevertheless, further research is warranted to elucidate the mechanisms through which sarcopenia impacts PD-1 inhibitors and to identify more efficacious intervention approaches for improving the effectiveness of PD-1 inhibitor treatment in sarcopenic patients.

|||||||||| Review, Journal: Role of Nonalcoholic Fatty Liver Disease in Periodontitis: A Bidirectional Relationship. (Pubmed Central) - Aug 5, 2024
Lifestyle modifications such as regular exercise, a healthy diet, and proper oral hygiene practices are crucial for preventing and managing these interconnected diseases. Additionally, interdisciplinary collaboration between hepatologists and periodontists is essential for optimizing patient care and improving outcomes in individuals with NAFLD and periodontitis.

|||||||||| Trial completion date, Trial primary completion date: Electrical Stimulation of Human Myocytes in Microgravity (clinicaltrials.gov) - Aug 5, 2024
P=N/A, N=75, Active, not recruiting, Sponsor: AdventHealth Translational Research Institute
Additionally, interdisciplinary collaboration between hepatologists and periodontists is essential for optimizing patient care and improving outcomes in individuals with NAFLD and periodontitis. Trial completion date: Jun 2024 --> Dec 2024 | Trial primary completion date: Jun 2024 --> Dec 2024

||||||||||  Edirol (eldecalcitol) / Roche, Taisho
New P4 trial:  Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia (clinicaltrials.gov) -  Aug 5, 2024
P4, N=450, Recruiting,  Sponsor: Zhejiang Provincial People's Hospital

|||||||||| Cohort profile: Study of MusculoskeletAl health in Renal Transplant patients (SMART) (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1555;

|||||||||| Application of Lower Extremity CT Auto Segmentation and AI-Based Pose Estimation for Sarcopenia Classification. (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1545;

|||||||||| Performance of a Machine Learning Model in the Selection of Articles for Systematic Reviews (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1544;

|||||||||| Do Sarcopenia and Dynapenia Predict Bone Health in Chronic Kidney Disease? (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1543;

|||||||||| Reference Data for Forearm and Leg Muscle Density Assessed by HRpQCT and Relationships with Physical Function (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1542;

|||||||||| Validating the SARC-F screening tool for sarcopenia among people aging with HIV (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1541;

|||||||||| Physical Activity Types and Sarcopenia among Middle-Aged and Older People: A Cross-Sectional Study (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1540;

|||||||||| Lack of Association Between Circulating BMP-7 Level and Sarcopenia in Older Asian Adults (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1539;

|||||||||| Associations Between Muscle Mass and Strength AND Bone Microarchitecture In Caucasian Postmenopausal Women (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1538;

|||||||||| Associations of Obesity Phenotypes with Incident Fall Rates: Results from the Objective Physical Activity and Cardiovascular Health in Older Women (OPACH) (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1536;

|||||||||| A Multi-Task Learning Framework Discovers Potential Drug-Repurposing Targets for Sarcopenia (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1349;

|||||||||| Muscle-Targeted Delivery of Osteocyte-Secreted Factor PGE2 for Sarcopenia Treatment (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1318;

|||||||||| Effect of Cocoa Flavanol Supplementation on Physical Performance Measures: results from the randomized controlled COcoa Supplement and Multivitamin Outcomes Study (COSMOS) (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1233;

|||||||||| The role of Bcl6 in determination of skeletal muscle mass and function (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1227;

|||||||||| Traditional Chinese medicine (TCM) formula Er Zhi Wan (EZW) ameliorates aging-induced muscle and bone loss in aging osteosarcopenic animal model (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1221;

|||||||||| Exploring the novel role of extra-renal Cyp27b1 in age-related muscle loss (Discovery Hall, Exhibit Hall E, 800 Level South) - Aug 5, 2024 - Abstract #ASBMR2024ASBMR_1216;



	Diseases Companies Products Productz Mechanisms of Action Sites