Sarcopenia
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  • ||||||||||  omega-3 ethylester concentrate / Generic mfg.
    Biomarker, Clinical, Journal:  Resistance Training Alone or Combined With N-3 PUFA-Rich Diet in Older Women: Effects on Muscle Fiber Hypertrophy. (Pubmed Central) -  Dec 28, 2019   
    There was also a significant hypertrophy of fast type IIA muscle fibers in RT-HD only (+23%, p < .05). In conclusion, resistance training combined to an N-3 PUFA-rich healthy diet but not alone triggers local anti-inflammatory and growth responses, favoring skeletal muscle hypertrophy in already recreationally active older women.
  • ||||||||||  Clinical, Journal:  Frailty syndrome in the elderly in elderly with chronic diseases in Primary Care. (Pubmed Central) -  Dec 28, 2019   
    The nursing diagnosis Frailty Syndrome in the Elderly allows a multidimensional view of the elderly. Since one factor can cause health problems in several health fields, nurses must intervene early, plan and implement actions in the short and long term.
  • ||||||||||  Journal:  Skeletal muscle mass and sarcopenia in nonalcoholic fatty liver disease. (Pubmed Central) -  Dec 26, 2019   
    A quick and easy radiological assessment of sarcopenia by measuring psoas density on preoperative CT scan using software universally available in the UK is highly predictive of postoperative morbidity in colorectal cancer patients. No abstract available
  • ||||||||||  Biomarker, Journal:  Noncontrast Chest Computed Tomographic Imaging of Obesity and the Metabolic Syndrome: Part II Noncardiovascular Findings. (Pubmed Central) -  Dec 25, 2019   
    These easily identified imaging biomarkers can have prognostic implications, which include nonalcoholic steatohepatitis, cirrhosis, hypothyroidism, early lung fibrosis with interstitial abnormalities, sarcopenia, and osteoporotic thoracic and lumbar spine vertebral body compression fractures. NCCT examinations of the chest have the opportunity to become an important imaging tool for outcomes research.
  • ||||||||||  Review, Journal:  Sarcopenia and Inflammatory Bowel Disease: A Systematic Review. (Pubmed Central) -  Dec 24, 2019   
    Improved perioperative intervention may diminish this risk. A formal assessment, screening by a dedicated IBD dietician, and preoperative physical therapy may facilitate early intervention.
  • ||||||||||  Journal:  The future of sarcopenia. (Pubmed Central) -  Dec 23, 2019   
    Recruiting --> Completed No abstract available
  • ||||||||||  Journal:  Ultrasound-based detection of glucocorticoid-induced impairments of muscle mass and structure in Cushing's disease. (Pubmed Central) -  Dec 23, 2019   
    No abstract available We provided preliminary evidence that the ultrasound-derived measurements of muscle thickness and echo intensity can be useful to detect and track the changes of muscle mass and structure in patients with steroid myopathy and we suggest that the combined assessment of muscle mass, strength, and performance should be systematically applied in the routine examination of steroid myopathy patients.
  • ||||||||||  Enrollment closed, Trial completion date:  Effects of Mobility Dose on Discharge Disposition in Critically Ill Stroke Patients (clinicaltrials.gov) -  Dec 23, 2019   
    P=N/A,  N=164, Active, not recruiting, 
    We provided preliminary evidence that the ultrasound-derived measurements of muscle thickness and echo intensity can be useful to detect and track the changes of muscle mass and structure in patients with steroid myopathy and we suggest that the combined assessment of muscle mass, strength, and performance should be systematically applied in the routine examination of steroid myopathy patients. Recruiting --> Active, not recruiting | Trial completion date: Dec 2019 --> Jun 2020
  • ||||||||||  Journal:  Sarcopenia and obesity. (Pubmed Central) -  Dec 23, 2019   
    Further research is needed to compare different definitions of sarcopenic/dynapenic obesity to clarify the relationship between obesity and the most important adverse outcomes in the elderly. The next step will be the definition of best possible therapeutic approaches for this condition.
  • ||||||||||  Journal:  The intestinal microbiome and its relevance for functionality in older persons. (Pubmed Central) -  Dec 23, 2019   
    CF, but not sarcopenia, is a robust predictor of severe postoperative complications in patients with colorectal cancer. The intestinal microbiome composition represents a possible determinant of functional performance in older people, and a promising target for antiaging therapeutic interventions.
  • ||||||||||  Clinical, Review, Journal:  Regulatory Mechanisms and Clinical Manifestations of Musculoskeletal Aging. (Pubmed Central) -  Dec 23, 2019   
    Advancements in the understanding of regulatory mechanisms of musculoskeletal aging may promote the development of novel treatments for age-related musculoskeletal disorders. Finally, future research directions for major musculoskeletal tissues including functional interaction between the tissues and their clinical relevance to age-related musculoskeletal disorders are highlighted in the future prospects section.
  • ||||||||||  Clinical, Journal:  Circuit Training Improvements in Korean Women with Sarcopenia. (Pubmed Central) -  Dec 23, 2019   
    On the other hand, the CG showed no significant changes. Circuit exercise training improves muscle mass and strength, body composition, balance, and pulmonary function in women with sarcopenia.
  • ||||||||||  NN1213 / Novo Nordisk
    Trial completion date:  ARMS-II: Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans (clinicaltrials.gov) -  Dec 23, 2019   
    P=N/A,  N=140, Recruiting, 
    Circuit exercise training improves muscle mass and strength, body composition, balance, and pulmonary function in women with sarcopenia. Trial completion date: Mar 2020 --> Mar 2021
  • ||||||||||  SARCOPENIA IN OLDER ADULTS UNDERGOING CARDIAC SURGERY (Posters Hall_Hall A) -  Dec 22, 2019 - Abstract #ACC2020ACC_6111;    
    ACS patients with sarcopenia were significantly worse prognosis than without sarcopenia. Abstract embargoed at this time.
  • ||||||||||  Journal:  Effects of elevated H and P on the contractile mechanics of skeletal muscle fibres from young and old men: implications for muscle fatigue in humans. (Pubmed Central) -  Dec 21, 2019   
    We reveal that the combination of acidosis (H ) and inorganic phosphate (P ) is an important mediator of muscle fatigue in humans by inhibiting the low- to high-force state of the cross-bridge cycle and peak power, but the depressive effects of these ions on cross-bridge function were similar in fibres from young and old men. These findings suggest the age-related loss in muscle power is due primarily to the atrophy of fast fibres, but the age-related increased fatigability cannot be explained by an increased sensitivity of the cross-bridge to H and P .