Sarcopenia
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  • ||||||||||  Clinical, Journal:  Deterioration of Brain Neural Tracts in Elderly Women with Sarcopenia. (Pubmed Central) -  Aug 30, 2020   
    The authors found that the neural tracts in elderly women with sarcopenia were extensively deteriorated, and their hand-grip power and memory function were associated with related neural tracts. The DTT seems to be a useful tool for evaluating structural changes in the brains of people with sarcopenia.
  • ||||||||||  Clinical, Review, Journal:  The clinical status and treatment options for osteoarthritis in patients with frailty (Pubmed Central) -  Aug 30, 2020   
    The review provides current information on the prevalence of OA and frailty, their clinical and prognostic significance, and also shows the mutually aggravating role of these two conditions. The difference between non - and medication management of patients with OA and frailty is emphasized.
  • ||||||||||  Review, Journal:  Effects of astaxanthin on the protection of muscle health (Review). (Pubmed Central) -  Aug 30, 2020   
    Mechanistic studies revealed that astaxanthin promotes muscle health by reducing oxidative stress, myoblast apoptosis and proteolytic pathways while promoting mitochondria regeneration and formation of blood vessels. Thus, astaxanthin is a potential therapeutic agent for sarcopenia but its effects in humans require further validation.
  • ||||||||||  Relationship between skeletal muscle index and arteriosclerosis during hemodialysis () -  Aug 30, 2020 - Abstract #JSN2020JSN_759;    
    After adjusting for age, gender, systolic blood pressure, glycoalbumin, history of cardiovascular events, and prealbumin using multivariate analysis, it was shown that SMI and baPWV were significantly associated (β=- 0.13, P=0.03). [Conclusion] It was shown that muscle mass and baPWV were related during the induction period of hemodialysis.
  • ||||||||||  Relationship between sarcopenia and osteoporosis in hemodialysis patients () -  Aug 30, 2020 - Abstract #JSN2020JSN_756;    
    Decreased SMI was associated with age, bone density, grip strength, BMI, %CGR, β2MG in men and history of dialysis, grip strength, BMI, and weight loss in women (p<0.05). Among 51 sarcopenia, an osteoporosis level of YAM 70% or lower was found in 25 men (69.4%) and 12 women (80%).
  • ||||||||||  Relationship between cortisol level during dialysis and dialysis starvation () -  Aug 30, 2020 - Abstract #JSN2020JSN_733;    
    [Discussion] Diabetic starvation mobilizes amino acids to gluconeogenesis and promotes protein catabolism, which may lead to sarcopenia. It is necessary to understand and control related factors to prevent starvation and maintain normal metabolism during the session.
  • ||||||||||  Overview (Room 12 (North 4F G403+G404)) -  Aug 30, 2020 - Abstract #JSN2020JSN_656;    
    Countermeasures against this problem are 1) intervention of dietitians as much as possible in order to accurately carry out diet therapy, 2) selection of subjects and changing priorities depending on the situation even for the same patient. It becomes a point.
  • ||||||||||  Is the target value for blood sugar control the same as for non-DKD? (Room 12 (North 4F G403+G404)) -  Aug 30, 2020 - Abstract #JSN2020JSN_582;    
    In such patients, it is necessary to loosen the blood glucose management target according to the individual patient background, and to evaluate and adjust the drug amount in a timely manner, and set a lower limit of the blood glucose management target to prevent hypoglycemia. This is very important.
  • ||||||||||  From the standpoint that protein restriction should be performed in CKD treatment (Room 12 (North 4F G403+G404)) -  Aug 30, 2020 - Abstract #JSN2020JSN_498;    
    In addition, the kidney disease medical treatment instructor is used to provide dietary instruction at the family doctor and dispensing pharmacy. In this symposium, the importance of protein intake restriction will be summarized from the perspective of Pros.
  • ||||||||||  From the standpoint that protein intake should not be restricted for CKD treatment (Room 12 (North 4F G403+G404)) -  Aug 30, 2020 - Abstract #JSN2020JSN_497;    
    Under these circumstances, not only are the problems of uniformly applying the currently recommended dietary standards pointed out, but there is also the opinion that it is time to reconsider the dietary regimen. In this workshop, from the standpoint that protein intake restriction should not be performed, I would like to discuss the problems caused by protein intake restriction in CKD patients and provide topics that can be the source of discussion.
  • ||||||||||  Frail or sarcopenia and renal rehabilitation after renal transplantation (Room 11 (North 4F G401+G402)) -  Aug 30, 2020 - Abstract #JSN2020JSN_495;    
    Therefore, we are focusing on renal rehabilitation at our institution, assessing exercise tolerance and muscle strength including CPX (cardiopulmonary exercise test) before transplantation, and exercise guidance to increase physical activity immediately after transplantation and vitamin D. Intervention therapy is performed with dietary guidance such as ingestion and certain effects are obtained. However, renal rehabilitation for renal transplant patients such as lack of evidence and maintenance of motivation of patients still has many problems, and future development is expected.
  • ||||||||||  Does Grip Strength Affect VA Patency? () -  Aug 30, 2020 - Abstract #JSN2020JSN_287;    
    In renal tissue, GLP-1RA administration caused glomerulosclerosis (PAS staining, type IV collagen), interstitial fibrosis (type I collagen). It is considered necessary to examine the relationship between the decrease in VA patency period and the decrease in grip strength.
  • ||||||||||  Diet in Diabetics-Focusing on Carbohydrate and Salt- (Room 2 (North, 3rd floor, G303+G304)) -  Aug 30, 2020 - Abstract #JSN2020JSN_276;    
    The association between overdose of salt and hypertension is widely known, and large-scale studies have shown the hypotensive effect of salt reduction. In this symposium, I would like to talk about diets that focus on carbohydrates and salt among the diets for diabetics.
  • ||||||||||  Changes in abdominal CT iliopsoas index in CKD patients () -  Aug 30, 2020 - Abstract #JSN2020JSN_149;    
    [Conclusion] In elderly CKD patients, muscle mass may decrease even if proper protein intake is performed. In order to prevent and improve sarcopenia, it is necessary to regularly evaluate individual conditions and provide nutritional guidance according to the condition.
  • ||||||||||  Analysis of the effects of indoxyl sulfate on mouse skeletal muscle and exploration of intervention () -  Aug 30, 2020 - Abstract #JSN2020JSN_84;    
    The changes were suppressed by the addition of β2-stimulants [Discussion] Since uremic toxin IS induced exercise tolerance/muscle weight reduction characteristic of sarcopenia in individual mice and decreased cell size/constitutive protein in cultured skeletal muscle cells, uremic toxin independently contributed to the development of sarcopenia in renal failure. There is a possibility that In the future, we will further explore the molecular pathways in which uremic toxin induces skeletal muscle and the pharmacological mechanisms that counteract it.
  • ||||||||||  AGE as a causative factor of sarcopenia/frail in CKD () -  Aug 30, 2020 - Abstract #JSN2020JSN_60;    
    Furthermore, there were decreased capillaries and mitochondrial dysfunction, which were completely improved by the administration of AGE aptamers. These results suggest that AGE may be involved in the development of sarcopenia/frail via endothelial dysfunction and mitochondrial dysfunction.
  • ||||||||||  [VIRTUAL] Significance of sarcopenia in infants with pediatric liver transplantation for biliary atresia (Channel 9) -  Aug 29, 2020 - Abstract #TTS2020TTS_507;    
    In sarcopenic patients, BW-SLV formulas are affected by a high risk of SLV underestimation, thus exposing them to an increased risk of post-LT SFSS. Sarcopenia in infants with BA before LT may be associated with patient survival and serve as a new and effective prognostic marker for growth retardation and postoperative outcomes of LT.
  • ||||||||||  Review, Journal:  The Mediterranean Diet Slows Down the Progression of Aging and Helps to Prevent the Onset of Frailty: A Narrative Review. (Pubmed Central) -  Aug 29, 2020   
    The Mediterranean diet is recognized to be a "healthy food" dietary pattern; high adherence to this dietary pattern is associated with a lower incidence of chronic diseases and lower physical impairment in old age. The aim of our review was to analyze observational studies (cohort and case-control studies) that investigated the effects of following a healthy diet, and especially the effect of adherence to a Mediterranean diet (MD), on the progression of aging and on onset of frailty.
  • ||||||||||  Journal:  Diagnosis of Presarcopenia Using Body Height and Arm Span for Postmenopausal Osteoporosis. (Pubmed Central) -  Aug 29, 2020   
    In the presarcopenia group diagnosed only by Arm span SMI (n=11), the arm span-height difference was significantly higher (p<0.001) and the percentage of young adult mean (YAM) femoral neck-BMD was significantly lower (p=0.013) compared to the normal group diagnosed by both SMI and Arm span-SMI (n=29). These results indicated that Arm span SMI might be useful for the diagnosis of sarcopenia in patients with severe osteoporosis and kyphosis.
  • ||||||||||  Journal:  COVID-19: a major cause of cachexia and sarcopenia? (Pubmed Central) -  Aug 29, 2020   
    These results indicated that Arm span SMI might be useful for the diagnosis of sarcopenia in patients with severe osteoporosis and kyphosis. No abstract available
  • ||||||||||  Clinical, Observational data, Journal:  Tongue thickness in health vs cirrhosis of the liver: Prospective observational study. (Pubmed Central) -  Aug 28, 2020   
    The patients with a CTP score ≥ 10 have significantly reduced tongue thickness as compared to normal individuals and those with less severe liver disease and CTP scores of 5-9. No significant difference in tongue thickness was found between healthy individuals and CTP class A and B patients.