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|||||||||| [VIRTUAL] Sarcopenia is Assocaited with Reduced Overall and Disease-Free Survival in Patients Undergoing Esophagectomy for Locally-Advanced Esophageal Cancer () - Oct 9, 2020 - Abstract #ACSCLINCON2020ACS_CLINCON_431;
Sarcopenia is associated with reduced OS and DFS in patients undergoing esophagectomy for LAEC.

|||||||||| Retrospective data, Journal: Letter to the Editor Regarding "Effect of Sarcopenia on Mortality After Percutaneous Vertebral Augmentation Treatment for Osteoporotic Vertebral Compression Fractures in Elderly Patients: A Retrospective Cohort Study". (Pubmed Central) - Oct 8, 2020
Sarcopenia is associated with reduced OS and DFS in patients undergoing esophagectomy for LAEC. No abstract available

|||||||||| Biomarker, Journal: Circulating Biomarkers of Accelerated Sarcopenia in Respiratory Diseases. (Pubmed Central) - Oct 8, 2020
We found a modest-to-significant increase in the plasma markers of inflammation, oxidative stress and muscle damage, which had varying degrees of correlations with Dkk-3, CAF22 and selected micro RNAs (miRs) in respiratory diseases. Taken together, our data show that plasma levels of Dkk-3, CAF22 and selected miRs can be useful tools to assess accelerated sarcopenia phenotype in the elderly with respiratory diseases.

|||||||||| Review, Journal: Nutrition and microRNAs: Novel Insights to Fight Sarcopenia. (Pubmed Central) - Oct 8, 2020
Besides, we explored the role of nutrition as a possible way to counteract the loss of muscle mass and function associated with ageing, with special attention paid to nutrient-dependent miRNAs regulation. This review will provide important information to better understand sarcopenia and, thus, to facilitate research and therapeutic strategies to counteract the pathophysiological effect of ageing.

|||||||||| New trial: Effects of Omega-3 Fatty Acids on Muscle Wasting (clinicaltrials.gov) - Oct 8, 2020
P, N=80, Enrolling by invitation, Sponsor: Karadeniz Technical University

|||||||||| [VIRTUAL] The impact of body composition on long‐term outcomes in patients with colorectal cancer () - Oct 8, 2020 - Abstract #ESCP2020ESCP_225;
This review will provide important information to better understand sarcopenia and, thus, to facilitate research and therapeutic strategies to counteract the pathophysiological effect of ageing. Visceral obesity does not seem to affect long‐term outcomes of patients with CRC, while sarcopenia presents a negative prognostic impact on both OS and CRS.

|||||||||| [VIRTUAL] Sarcopenia to predict overall survival in head and neck cancer patients receiving chemotherapy: A systematic review and meta-analysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1298;
Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| everolimus / Generic mfg.
[VIRTUAL] Prognostic value of sarcopenia in metastatic renal cell carcinoma patients: A systematic review (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1252;
However, other 2 studies found that there were no significant differences in chemotherapy toxicity between sarcopenic and non-sarcopenic patients treated with tyrosine kinase inhibitor and everolimus...Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among pancreatic cancer patients who underwent chemotherapy: A systematic review and meta:analysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1236;
Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| [VIRTUAL] Effect of sarcopenia on short - and long-term outcomes of patients with gastric neuroendocrine tumour after radical surgery: Results from a large, two-institutional series (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1233;
Legal entity responsible for the study: The authors. Funding: Scientific and Technological Innovation Joint Capital Projects of Fujian Province.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among hepatocellular carcinoma patients who underwent chemotherapy: A systematic review and meta-analysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1213;
Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| [VIRTUAL] Assessment of nutritional status of colorectal cancer patients in a tertiary government hospital (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1151;
Legal entity responsible for the study: The authors. Funding: Philippine General Hospital.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among colorectal cancer patients who underwent chemotherapy: A systematic review and meta:analysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1144;
Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| [VIRTUAL] Correlation of muscle strength and quality of life in Indonesian breast cancer patients who underwent chemotherapy (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_1096;
Legal entity responsible for the study: The authors. Funding: Has not received any funding.

|||||||||| [VIRTUAL] Sarcopenia to predict overall survival in head and neck cancer patients receiving chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_933;
This finding can be used by physicians to improve the assessment of risk and benefit of initiating or continuing chemotherapy in these patients. Further study needs to evaluate in better patient selection and adjusting the confounder.

|||||||||| everolimus / Generic mfg.
[VIRTUAL] Prognostic value of sarcopenia in metastatic renal cell carcinoma patients: A systematic review (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_887;
However, other 2 studies found that there were no significant differences in chemotherapy toxicity between sarcopenic and non-sarcopenic patients treated with tyrosine kinase inhibitor and everolimus...There were 5 studies with good quality, 4 studies with moderate quality, and 1 study with poor quality. Further investigation is needed with better methods and outcome that focuses on chemotherapy toxicity and quality of life.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among pancreatic cancer patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_871;
Sarcopenia can give negative impact on chemotherapy toxicities and survival outcomes for pancreatic cancer patients who underwent chemotherapy. Therefore, it is important to diagnose and treat sarcopenia to reduce the chemotherapy toxicity and mortality in pancreatic cancer patients.

|||||||||| [VIRTUAL] Effect of sarcopenia on short and longterm outcomes of patients with gastric neuroendocrine tumour after radical surgery: Results from a large, twoinstitutional series (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_868;
Sarcopenia is an independent risk factor for patients with gMANEC after radical surgery. Scientific and Technological Innovation Joint Capital Projects of Fujian Province.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among hepatocellular carcinoma patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_848;
Sarcopenia can give negative impact on chemotherapy toxicities and survival outcomes for hepatocellular carcinoma patients who underwent chemotherapy. Prospective studies with a uniform definition of sarcopenia and same chemotherapy regimen are still needed.

|||||||||| [VIRTUAL] Assessment of nutritional status of colorectal cancer patients in a tertiary government hospital (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_786;
Thus, a hospital-wide program focusing on early nutritional assessment is recommended for implementation. Philippine General Hospital.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among colorectal cancer patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_779;
Sarcopenia and low muscle mass can give negative impact on chemotherapy toxicities and survival outcomes for colorectal cancer patients who underwent chemotherapy. Prospective studies with a uniform definition of sarcopenia are still needed to update our findings.

|||||||||| [VIRTUAL] Correlation of muscle strength and quality of life in Indonesian breast cancer patients who underwent chemotherapy (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_731;
Overall, nearly all of the domains have good outcomes. Further assessment in patients’ nutritional status and physical activity were needed.

|||||||||| [VIRTUAL] Sarcopenia to predict overall survival in head and neck cancer patients receiving chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_566;
This finding can be used by physicians to improve the assessment of risk and benefit of initiating or continuing chemotherapy in these patients. Further study needs to evaluate in better patient selection and adjusting the confounder.

|||||||||| everolimus / Generic mfg.
[VIRTUAL] Prognostic value of sarcopenia in metastatic renal cell carcinoma patients: A systematic review (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_518;
However, other 2 studies found that there were no significant differences in chemotherapy toxicity between sarcopenic and non-sarcopenic patients treated with tyrosine kinase inhibitor and everolimus...There were 5 studies with good quality, 4 studies with moderate quality, and 1 study with poor quality. Further investigation is needed with better methods and outcome that focuses on chemotherapy toxicity and quality of life.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among pancreatic cancer patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_498;
Sarcopenia can give negative impact on chemotherapy toxicities and survival outcomes for pancreatic cancer patients who underwent chemotherapy. Therefore, it is important to diagnose and treat sarcopenia to reduce the chemotherapy toxicity and mortality in pancreatic cancer patients.

|||||||||| [VIRTUAL] Effect of sarcopenia on short and longterm outcomes of patients with gastric neuroendocrine tumour after radical surgery: Results from a large, twoinstitutional series (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_495;
Sarcopenia is an independent risk factor for patients with gMANEC after radical surgery. Scientific and Technological Innovation Joint Capital Projects of Fujian Province.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among hepatocellular carcinoma patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_475;
Sarcopenia can give negative impact on chemotherapy toxicities and survival outcomes for hepatocellular carcinoma patients who underwent chemotherapy. Prospective studies with a uniform definition of sarcopenia and same chemotherapy regimen are still needed.

|||||||||| [VIRTUAL] Assessment of nutritional status of colorectal cancer patients in a tertiary government hospital (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_412;
Thus, a hospital-wide program focusing on early nutritional assessment is recommended for implementation. Philippine General Hospital.

|||||||||| [VIRTUAL] The impact of sarcopenia on chemotherapy toxicity and survival rate among colorectal cancer patients who underwent chemotherapy: A systematic review and metaanalysis (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_405;
Sarcopenia and low muscle mass can give negative impact on chemotherapy toxicities and survival outcomes for colorectal cancer patients who underwent chemotherapy. Prospective studies with a uniform definition of sarcopenia are still needed to update our findings.

|||||||||| [VIRTUAL] Correlation of muscle strength and quality of life in Indonesian breast cancer patients who underwent chemotherapy (On-Demand e-Poster Display) - Oct 8, 2020 - Abstract #ESMOAsia2020ESMO_Asia_355;
Overall, nearly all of the domains have good outcomes. Further assessment in patients’ nutritional status and physical activity were needed.

|||||||||| Clinical, Journal: EFFECTS OF WHOLE BODY VIBRATION TRAINING ON THE PHYSICAL FUNCTION OF THE FRAIL ELDERLY: an open, randomised control trial. (Pubmed Central) - Oct 8, 2020
Further assessment in patients’ nutritional status and physical activity were needed. Findings indicate that 16-weeks of low-level WBV-exercise provides easily-accessible, adequate stimulus for the frail elderly to attain improved levels of physical functionality.

|||||||||| Clinical, Journal: Handgrip Strength and Timed Up-and-Go (TUG) Test are Predictors of Short-Term Mortality among Elderly in a Population-Based Cohort in Singapore. (Pubmed Central) - Oct 8, 2020
Findings indicate that 16-weeks of low-level WBV-exercise provides easily-accessible, adequate stimulus for the frail elderly to attain improved levels of physical functionality. Among elderly in a Chinese population, handgrip strength and TUG test were strong and independent predictors of short-term mortality.

|||||||||| Journal: Sarcopenia, Obesity and Sarcopenia Obesity in Comparison: Prevalence, Metabolic Profile, and Key Differences: Results from WCHAT Study. (Pubmed Central) - Oct 8, 2020
The prevalence of S and SO has an aging increase pattern contrary to O. Both S and SO tend to be older, lower educational level, without spouse, smoking, comorbidity of chronic disease, poor nutrition status, depression and cognitive decline compared to H and S looks like to be worse than SO. Besides, the S subjects seem to have more metabolic index changes than SO compared to H. While O subjects have some contrary metabolic index to S subjects.

|||||||||| Clinical, Journal: Sarcopenia among patients after allogeneic hematopoietic stem cell transplantation and the impact of chronic graft-versus-host disease. (Pubmed Central) - Oct 8, 2020
Sarcopenia was found to be common in long term survivors of allo-HSCT independently of the cGVHD diagnosis. Prospective longitudinal studies are needed for a better understanding of factors affecting the development of sarcopenia after allo-HSCT.

|||||||||| Journal: Letter to the Editor: COVID-19 Quarantine in Older People: The Need to Think about Sarcopenia-Related Phenotypes. (Pubmed Central) - Oct 8, 2020
Prospective longitudinal studies are needed for a better understanding of factors affecting the development of sarcopenia after allo-HSCT. No abstract available

|||||||||| [VIRTUAL] Usefulness of Ultrasound Assessment of Sarcopenia in Patients with Rheumatoid Arthritis () - Oct 8, 2020 - Abstract #ACRARHP2020ACR_ARHP_2232;
In addition, it showed significant correlation with both muscle volume and physical function. We suggest muscle US can be used as an assessment tool of sarcopenia in patients with RA and further studies incorporating more patients and longitudinal follow up would be needed.

|||||||||| [VIRTUAL] Association of Frailty with Disability Is Not Attenuated by Lean Body Mass in Women with SLE () - Oct 8, 2020 - Abstract #ACRARHP2020ACR_ARHP_1941;
Sarcopenia was more common among frail than pre-frail and non-frail women with SLE. The association of frailty with disability was not attenuated by multiple covariates, including lean body mass.

|||||||||| prednisone / Generic mfg.
[VIRTUAL] Frailty and Health-Related Quality of Life in Patients with Polymyalgia Rheumatica () - Oct 8, 2020 - Abstract #ACRARHP2020ACR_ARHP_1013;
Frailty was associated with worse physical function and increased fatigue, pain behavior and pain interference, differences that were clinically meaningful and statistically significant. Study limitations include the relatively small, homogenous sample size and missing data regarding sarcopenia.

|||||||||| Clinical, Clinical data, Journal, Adverse events: Limited performance of subjective global assessment compared to computed tomography-determined sarcopenia in predicting adverse clinical outcomes in patients with cirrhosis. (Pubmed Central) - Oct 7, 2020
Sarcopenia was associated with mortality, whereas SGA was not. Sarcopenia by the SMI is a more efficient method to predict adverse outcomes in a timely fashion and has prognostic implications.

|||||||||| Journal: Bone mineral density correlates with survival after resection of extrahepatic biliary malignancies. (Pubmed Central) - Oct 7, 2020
Preoperative low BMD is closely related to mortality and cancer recurrence after the resection of extrahepatic biliary cancers. BMD screening in patients with cancer should be further highlighted in the oncology field.

|||||||||| Clinical, Journal: Sarcopenia as a predictor of poor surgical and oncologic outcomes after abdominal surgery for digestive tract cancer: A prospective cohort study. (Pubmed Central) - Oct 7, 2020
Sarcopenia could be used as a strong and independent prognostic factor for poor surgical and oncologic outcomes in patients after abdominal surgery for digestive tract cancer. Identification of preoperative sarcopenia in digestive surgery for cancer and targeted approaches may improve its negative outcomes.

|||||||||| Clinical, Journal: Identifying High-Attenuating and Low-Attenuating Muscle Using Computerized Tomography and Exploring Its Impact on Physical Function and Muscle Strength in Obese Critically Ill Patients. (Pubmed Central) - Oct 7, 2020
Greater total high-attenuating psoas CSA moderately correlated with muscle strength. Additional studies using more objective markers of muscle strength validating these findings are needed.

|||||||||| Clinical, Journal: The value of different CT-based methods for diagnosing low muscle mass and predicting mortality in patients with cirrhosis. (Pubmed Central) - Oct 7, 2020
Gender-specific TPMT, SMI and PSMI cut-offs for low muscle mass can identify patients with an increased risk for mortality. Importantly, only TPMT emerged as an independent risk factor for mortality in patients with cirrhosis.

|||||||||| Review, Journal: Hepatic Encephalopathy and Nutrition Influences: A Narrative Review. (Pubmed Central) - Oct 7, 2020
This debilitating condition is associated with increased morbidity and mortality and imposes a significant burden on the caregivers and healthcare system. After providing an overview of HE epidemiology and pathophysiology, this review focuses on the interaction of HE and frailty, nutrition requirements and recommendations in cirrhotic patients with HE, and current dietary and pharmacologic options for HE treatment.

|||||||||| Clinical: Hi Chris, the slide discussed RT reducing fall & fracture ‘risk factors’ I.e sarcopenia & osteoporosis. Later in the pres mentions need for balance & co-ordination training etc as part of programming. 👍 (Twitter) - Oct 7, 2020

|||||||||| #CLSAFindings💡: The impact of different diagnostic criteria on the association of sarcopenia with injurious falls in the CLSA: https://t.co/pGSRDUwXot @mackinprof @PaulDMcNicholas @macgparise @HEI_mcmaster @MIRAMcMaster @MacKinesiology (Twitter) - Oct 7, 2020

|||||||||| Clinical, Journal: Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: A prospective study from UK Biobank. (Pubmed Central) - Oct 7, 2020
After providing an overview of HE epidemiology and pathophysiology, this review focuses on the interaction of HE and frailty, nutrition requirements and recommendations in cirrhotic patients with HE, and current dietary and pharmacologic options for HE treatment. Associations of sarcopenia with adverse outcomes were strongest when sarcopenia was defined as slow gait speed plus low muscle mass, followed by severe sarcopenia, suggesting that this combination of physical capability markers should be still considered in the diagnosis of sarcopenia.

|||||||||| Review, Journal: Mitochondrial Dysfunction in Kidney Disease and Uremic Sarcopenia. (Pubmed Central) - Oct 7, 2020
This review provides an overview of the mitochondrial change in the kidney and skeletal muscle, which is often complicated with sarcopenia and chronic kidney disease (CKD). Furthermore, the pharmacological effects of therapeutics for CKD on mitochondria are explored.

|||||||||| Journal: A low psoas muscle volume is associated with a poor prognosis in penile cancer. (Pubmed Central) - Oct 7, 2020
Furthermore, the pharmacological effects of therapeutics for CKD on mitochondria are explored. Sarcopenia might be a useful prognostic factor in penile cancer patients.

|||||||||| Clinical, Journal: Impact of Sarcopenia on Survival in Patients With Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy. (Pubmed Central) - Oct 7, 2020
Increasing BMI is associated with improved OS. Future, prospective work is needed to define the impact of sarcopenia and other fitness metrics on clinical outcomes among NSCLC patients treated non-invasively with SBRT.



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