Sarcopenia
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  • ||||||||||  Journal:  Quantitative Imaging of Body Composition. (Pubmed Central) -  Jun 22, 2021   
    Multiple imaging methods have allowed precise estimates of tissue types and provided insights showing the relationship of body composition to varied pathologic conditions. In this review article, we discuss different imaging methods used to quantify body composition and describe important anatomical locations where target tissues can be measured.
  • ||||||||||  Clinical, Journal:  Establishing Reference Values for Lean Muscle Mass in the Pediatric Patient. (Pubmed Central) -  Jun 22, 2021   
    We created gender-specific reference charts for total and height-normalized psoas muscle area in healthy children based on age. These results can be used in future studies to establish the effects of sarcopenia in pediatric patients.
  • ||||||||||  Clinical, Journal:  Sarcopenia as independent risk factor of postpneumonectomy respiratory failure, ARDS and mortality. (Pubmed Central) -  Jun 22, 2021   
    These results can be used in future studies to establish the effects of sarcopenia in pediatric patients. Sarcopenia defined as the sex-related 33rd percentile of fat-excluded TMA at the level of the third lumbar vertebra is the most discriminating parameter to assess short-term-outcome in patients undergoing pneumonectomy.
  • ||||||||||  Clinical, Journal:  Sarcopenia screening in elderly in primary health care: nurse knowledge and practices. (Pubmed Central) -  Jun 22, 2021   
    This reality is reflected in a gap in practice, although some instruments already require the registration of characteristics indicative of sarcopenia, such as the evaluation of the calf circumference. The need to train nurses to perform sarcopenia screening and to implement a promotional and preventive care plan, which will result in improving the quality of life of the elderly assisted in Primary Care, was highlighted.
  • ||||||||||  Clinical, Review, Journal:  Clinical Impact of a Perioperative Exercise Program for Sarcopenia and Overweight/Obesity Gastric Cancer. (Pubmed Central) -  Jun 22, 2021   
    However, whether or not perioperative exercise programs have clinical benefits with regard to long-term oncological outcomes in gastric cancer patients is unclear. To optimize these perioperative exercise programs for gastric cancer patients, it is necessary to clarify the benefits with regard to the long-term oncological outcomes in these patients and establish an optimal perioperative exercise program.
  • ||||||||||  Journal:  Sarcopenia and TIPS: How Best to Measure Muscle Mass. (Pubmed Central) -  Jun 22, 2021   
    A full diagnosis of malnutrition seems more useful than a simple malnutrition screening to predict the incidence of sarcopenia over 5 years. No abstract available
  • ||||||||||  Clinical, Journal:  Poor handgrip strength determined clinically is associated with falls in older women. (Pubmed Central) -  Jun 22, 2021   
    Poor HGS based on clinical criterion is independently associated with higher risk of falls in older women, particularly in those with impaired balance. These results suggest potential prognostic value of FNIH Sarcopenia threshold for risk stratification and referring high-risk individuals to fall prevention programs.
  • ||||||||||  NN1213 / Novo Nordisk
    Trial completion, Enrollment change:  Trial of Oral Glutamine on Mitochondrial Function in CKD (clinicaltrials.gov) -  Jun 22, 2021   
    P2,  N=11, Completed, 
    Grip strength assessment is acceptable to physiotherapy staff and can be rapidly and cost-effectively implemented into hip fracture admission assessment. Recruiting --> Completed | N=20 --> 11
  • ||||||||||  Clinical, Journal:  Sarcopenia index in hospitalized patients with chronic obstructive pulmonary disease exacerbation (Pubmed Central) -  Jun 22, 2021   
    In patients admitted for COPD exacerbation, the sarcopenia index was related to prognostic characteristics, so that lower values were associated with longer duration of hospital admission, more dyspnoea and greater functional impairment. As this is an index associated with muscle mass, its determination may identify patients who could be the subject of a differentiated therapeutic plan.
  • ||||||||||  Clinical, Review, Journal:  Assessment of the Frail Patient With End-Stage Liver Disease: A Practical Overview of Sarcopenia, Physical Function, and Disability. (Pubmed Central) -  Jun 22, 2021   
    However, over the last decade, numerous nonspecific and specific tools have emerged. The current evidence supports the use of a combination of simple, user-friendly, objective measures to first identify frailty in ESLD (notably Clinical Frailty Scale, Liver Frailty Index), followed by a combination of serial tools to assess specifically sarcopenia (i.e., muscle ultrasound), physical function (i.e., chair stands, hand grip strength), functional capacity (i.e., 6-minute walk test), and physical disability (i.e., activities of daily living).
  • ||||||||||  Review, Journal:  Regulation of Skeletal Muscle Satellite Cell Differentiation by Omega-3 Polyunsaturated Fatty Acids: A Critical Review. (Pubmed Central) -  Jun 22, 2021   
    Omega-3 polyunsaturated fatty acids (PUFAs) show promise to reduce inflammation, maintain muscle mass during aging, and increase the functional capacity of the muscle. The aim of this critical review is to highlight the role of omega-3 PUFAs on the myogenic differentiation of SCs and pathways affected during the differentiation process, including mitochondrial function and inflammation from the current body of literature.
  • ||||||||||  Clinical, Journal:  Longitudinal changes in physical and mental health of older adults with chronic hepatitis B infection: Trajectories and predictors. (Pubmed Central) -  Jun 22, 2021   
    Three baseline characteristics were independently associated with a lower likelihood of remaining physically or mentally healthy: sarcopenic obesity (odds ratio [OR] with 95% confidence interval [95% CI] of 7.5 [2.8-20.5] for poor physical health, 3.1 [1.1-8.4] for declining physical health, 4.3 [1.4-13.0] for poor mental health), a higher number of metabolic abnormalities (OR [95% CI] of 3.6 [1.6-8.0] for poor physical health) and depressed mood (OR [95% CI] of 21.7 [5.8-81.0] for poor physical health, 5.3 [1.4-19.9] for declining physical health, 83.1 [19.7-350.2] for poor mental health, 13.6 [2.9-64.8] for declining mental health). In conclusion, in a cohort of elderly patients with CHB, we demonstrated the heterogeneity and nonlinearity of HRQoL changes and their associations with variations in specific extrahepatic organs/systems.
  • ||||||||||  [VIRTUAL] Radiologic Sarcopenia And Nutritional Status In Critically Ill Trauma Patients (Virtual) -  Jun 20, 2021 - Abstract #ASA2021ASA_798;    
    There was no difference in M-Area or P-Area between high risk and low risk nutritional groups. However, there was a trend towards smaller M-Area in the high risk nutritional group which suggests that potentially a larger sample size may identify M-Area as a marker of poor nutrition in critically ill trauma patients.