Sarcopenia
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  • ||||||||||  Journal:  Sarcopenic obesity and its association with respiratory disease incidence and mortality. (Pubmed Central) -  Aug 21, 2021   
    Obesity, sarcopenia and sarcopenic obesity were associated with a higher risk of respiratory disease incidence. However, while obesity was associated with lower, and sarcopenia with higher respiratory mortality risk, no associations between sarcopenic obesity and respiratory mortality were identified.
  • ||||||||||  Clinical, Journal:  Skeletal muscle loss phenotype in cirrhosis: A nationwide analysis of hospitalized patients. (Pubmed Central) -  Aug 21, 2021   
    However, while obesity was associated with lower, and sarcopenia with higher respiratory mortality risk, no associations between sarcopenic obesity and respiratory mortality were identified. Muscle loss contributed to higher mortality, LOS, and direct healthcare costs in hospitalized cirrhotics.
  • ||||||||||  Review, Journal:  Perioperative nutrition: Recommendations from the ESPEN expert group. (Pubmed Central) -  Aug 21, 2021   
    Muscle loss contributed to higher mortality, LOS, and direct healthcare costs in hospitalized cirrhotics. Nutritional assessment of the surgical patient together with the appropriate interventions to restore the energy deficit, avoid weight loss, preserve the gut microbiome and improve functional performance are all necessary components of the nutritional, metabolic and functional conditioning of the surgical patient.
  • ||||||||||  Journal:  Macronutrient composition and sarcopenia in the oldest-old men: The Helsinki Businessmen Study (HBS). (Pubmed Central) -  Aug 21, 2021   
    Nutritional assessment of the surgical patient together with the appropriate interventions to restore the energy deficit, avoid weight loss, preserve the gut microbiome and improve functional performance are all necessary components of the nutritional, metabolic and functional conditioning of the surgical patient. These findings suggest that sufficient energy and protein intakes, but also fat quality may be important along with healthy dietary patterns for prevention of sarcopenia in the oldest-old.
  • ||||||||||  Clinical, Journal:  ESPEN practical guideline: Clinical nutrition in liver disease. (Pubmed Central) -  Aug 21, 2021   
    GLIM criteria and the 7 approaches predicted three-to four-fold mortality, all ensured an accurate diagnosis, and were feasible in clinical settings. This practical guideline gives guidance to health care providers involved in the management of liver disease to offer optimal nutritional care.
  • ||||||||||  Journal:  Micronutrient malnutrition across the life course, sarcopenia and frailty. (Pubmed Central) -  Aug 21, 2021   
    Further research is needed in all these areas. Comprehensive public health and government approaches to ensure access and affordability of good quality foods to populations of all ages, particularly during the ongoing COVID-19 epidemic, are crucial.
  • ||||||||||  iPS cell therapy / University of Minnesota
    Review, Journal:  Myogenic Cell Transplantation in Genetic and Acquired Diseases of Skeletal Muscle. (Pubmed Central) -  Aug 20, 2021   
    As for any cell transplantation procedure, the choice between autologous and heterologous cells is dictated by a number of criteria, such as cell availability, possibility of in vitro expansion to reach the number required, need for genetic correction for many but not necessarily all muscular dystrophies, and immune reaction, mainly to a heterologous, even if HLA-matched cells and, to a minor extent, to the therapeutic gene product, a possible antigen for the patient. Finally, induced pluripotent stem cell derivatives, that have entered clinical experimentation for other diseases, may in the future offer a bank of immune-privileged cells, available for all patients and after a genetic correction for muscular dystrophies and other myopathies.
  • ||||||||||  Clinical, Journal:  Relationship of kidney functions with geriatric syndromes in elderly and old women. (Pubmed Central) -  Aug 20, 2021   
    Undoubtedly, the negative role of severe late stages of CKD in the development of senile asthenia and sarcopenia, at the same time, the relationship of these geriatric syndromes with early pre-dialysis stages of CKD has been insufficiently studied. Therefore, it is of undoubted scientific interest to identify correlations between signs of sarcopenia and frailty in elderly and senile women, depending on renal function, stage of CKD.
  • ||||||||||  Journal:  Associations between dietary patterns at age 71 and the prevalence of sarcopenia 16 years later. (Pubmed Central) -  Aug 20, 2021   
    In this prospective study of elderly men, using a single measure of diet at age 71 as a reflection of habitual dietary habits, healthy dietary patterns tended to protect against the development of sarcopenia over 16 years. In particular, we found indications that increased adherence to a Mediterranean dietary pattern might be advantageous.
  • ||||||||||  Clinical, Journal:  Nutritional condition analysis of the older adult patients with femoral neck fracture. (Pubmed Central) -  Aug 20, 2021   
    When both were presented in the sarcopenic state, the risk of NAFLD was higher, and a concurrence of sarcopenia and obesity showed the highest risk of NAFLD. Malnutrition contributes to the development of femoral neck fracture, according to the BIA analysis, aLM, rather than FM is a protection factor for the older people to get rid of femoral neck fracture.
  • ||||||||||  Clinical, Journal:  Resistance Training Increases Muscle Strength and Muscle Size in Patients With Liver Cirrhosis. (Pubmed Central) -  Aug 20, 2021   
    P=N/A
    In a randomized trial of patients with compensated cirrhosis, we found that 12 weeks of supervised progressive resistance training increased muscle strength and size and had beneficial effects on general performance measures, compared with patients who did not change their daily activity routine (controls). ClinicalTrials.gov no: NCT02343653.
  • ||||||||||  Review, Journal:  Critical appraisal of definitions and diagnostic criteria for sarcopenic obesity based on a systematic review. (Pubmed Central) -  Aug 20, 2021   
    The results of the current work support the need for consensus proposals on: 1) definition of sarcopenic obesity; 2) diagnostic criteria both at the level of potential gold-standards and acceptable surrogates with wide clinical applicability, and with related cut-off values; 3) methodologies to be used in actions 1 and 2. First steps should be aimed at reaching consensus on plausible proposals that would need subsequent validation based on homogeneous studies and databases, possibly based on analyses of existing cohorts, to help define the prevalence of the condition, its clinical and functional relevance as well as most effective prevention and treatment strategies.
  • ||||||||||  Review, Journal:  Exercise and Nutritional Approaches to Combat Cancer-Related Bone and Muscle Loss. (Pubmed Central) -  Aug 20, 2021   
    This review identifies specific components of nutrition and exercise interventions that are promising although require further exploration through studies designed to determine the effect on muscle and bone. A focused research effort is required to elucidate the full potential of exercise and nutrition intervention for people with cancer at risk of bone and muscle loss.
  • ||||||||||  Clinical, Journal:  Is peak expiratory flow an accurate sarcopenia screening tool in older patients referred to respiratory rehabilitation? (Pubmed Central) -  Aug 20, 2021   
    The impact of the adjustment methods, the characteristics of the study population, and the regional thresholds should be taken into consideration while evaluating the results of sarcopenia studies. Considering the EWGSOP-2 criteria as the reference standard, a cut-off of PEF ≤ 200 L/min showed only fair validity for detecting sarcopenia, so it cannot be recommended as a stand-alone screening tool in older rehabilitation patients with COPD.
  • ||||||||||  Clinical, Journal:  Adiposity is inversely associated with strength in older adults with type 2 diabetes mellitus. (Pubmed Central) -  Aug 20, 2021   
    Adiposity, independent of the criteria used, was inversely associated with muscle strength, suggesting that adiposity negatively influences muscle quality in older adults with T2DM. Screening for poor muscle strength and quality has the potential to facilitate early exercise and dietary interventions aimed at preserving muscle function in older adults with T2DM.