Salivary Gland Diseases MOAs - LARVOL Sigma

Salivary Gland Diseases

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52 Mechanisms of Action


Phase N/A 1 2 3 4 Products		0	2										4										6										8										10										12										14										16										18										20



c-KIT inhib




Tubulin inhib




CD20 inhib




EGFR inhib




Tubulin inhib




VEGF inhib




AKT inhib




PDGFR inhib




c-KIT inhib




CD20 inhib




HIF-1 inhib




DNA cross linking agent




HER2 inhib




AKT inhib




Acetylcholine inhib




Bcl2 inhib




Bcl2 inhib




Glutamate receptor antag




IL-1β inhib




IMPDH inhib




Immunosuppressant




NMDAR antag




PI3K inhib




Substance P release inhib




TNF inhib




mTOR inhib




Angiogenesis inhib




BAFF inhib




BRAF inhib




CD11a antag




CD20 inhib




CD4 T cell mod




Cadherin mod




FGFR2 inhib




Fyn inhib




GM-CSF agon




GM-CSF agon




HIF-1 inhib




IGF-1R inhib




IL-1β inhib




IL-6 antag




IgE inhib




Lymphotoxin-β inhib




Muscarinic receptor antag




PARP2 inhib




Proteasome inhib




RAF kinase inhib




STAT3 inhib




Serotonin 1D receptor agon




TLR8 agon